Result of FASTA (omim) for
pFN21AE6110
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6110, 161 aa
1>>>pF1KE6110 161 - 161 aa - 161 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7600+/-0.000377; mu= 17.2700+/- 0.024
mean_var=119.3105+/-22.573, 0's: 0 Z-trim(116.2): 212 B-trim: 33 in 1/57
Lambda= 0.117418
statistics sampled from 26922 (27179) to 26922 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.319), width: 16
Scan time: 4.690
The best scores are: opt bits E(85289)
NP_003271 (OMIM: 191040,611879,613243) troponin C, ( 161) 1058 189.3 2.2e-48
NP_003270 (OMIM: 191039) troponin C, skeletal musc ( 160) 673 124.1 9.5e-29
XP_011527333 (OMIM: 191039) PREDICTED: troponin C, ( 145) 650 120.2 1.3e-27
NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149) 512 96.8 1.5e-20
NP_008819 (OMIM: 114180,614916,616247) calmodulin ( 149) 512 96.8 1.5e-20
NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149) 512 96.8 1.5e-20
NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149) 512 96.8 1.5e-20
XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150) 512 96.8 1.5e-20
NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197) 512 97.0 1.7e-20
NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149) 488 92.7 2.5e-19
NP_001292555 (OMIM: 114182,616249) calmodulin isof ( 113) 400 77.7 6.5e-15
NP_001316854 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 400 77.7 6.5e-15
NP_001316855 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 400 77.7 6.5e-15
NP_001316850 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 400 77.7 6.5e-15
NP_001316853 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 400 77.7 6.5e-15
NP_001316852 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 400 77.7 6.5e-15
NP_001292554 (OMIM: 114182,616249) calmodulin isof ( 113) 400 77.7 6.5e-15
NP_004057 (OMIM: 603187) centrin-1 [Homo sapiens] ( 172) 375 73.7 1.6e-13
NP_004335 (OMIM: 300006) centrin-2 [Homo sapiens] ( 172) 365 72.0 5e-13
NP_001317242 (OMIM: 610171) calmodulin-like protei ( 164) 352 69.8 2.3e-12
NP_619650 (OMIM: 610171) calmodulin-like protein 6 ( 181) 352 69.8 2.4e-12
XP_005244786 (OMIM: 610171) PREDICTED: calmodulin- ( 203) 352 69.9 2.5e-12
NP_004267 (OMIM: 605563) calcium-binding protein 1 ( 167) 324 65.0 6.1e-11
NP_112482 (OMIM: 605563) calcium-binding protein 1 ( 227) 324 65.2 7.2e-11
NP_001028849 (OMIM: 605563) calcium-binding protei ( 370) 324 65.5 9.5e-11
NP_059118 (OMIM: 605183) calmodulin-like protein 5 ( 146) 309 62.4 3.3e-10
XP_016875728 (OMIM: 605563) PREDICTED: calcium-bin ( 202) 302 61.4 9e-10
NP_002466 (OMIM: 609930) myosin light chain 6B [Ho ( 208) 302 61.4 9.1e-10
NP_001186558 (OMIM: 609930) myosin light chain 6B ( 208) 302 61.4 9.1e-10
XP_016875727 (OMIM: 605563) PREDICTED: calcium-bin ( 262) 302 61.6 1e-09
XP_016875724 (OMIM: 605563) PREDICTED: calcium-bin ( 405) 302 61.9 1.3e-09
XP_011543485 (OMIM: 608965,610427) PREDICTED: calc ( 170) 292 59.6 2.6e-09
NP_001287824 (OMIM: 608965,610427) calcium-binding ( 170) 292 59.6 2.6e-09
NP_001287825 (OMIM: 608965,610427) calcium-binding ( 170) 292 59.6 2.6e-09
XP_016873514 (OMIM: 608965,610427) PREDICTED: calc ( 170) 292 59.6 2.6e-09
NP_660201 (OMIM: 608965,610427) calcium-binding pr ( 275) 292 59.9 3.4e-09
XP_011543483 (OMIM: 608965,610427) PREDICTED: calc ( 295) 292 60.0 3.6e-09
NP_066299 (OMIM: 609931) myosin light polypeptide ( 151) 276 56.8 1.6e-08
NP_524147 (OMIM: 609931) myosin light polypeptide ( 151) 276 56.8 1.6e-08
NP_000249 (OMIM: 160790,608751) myosin light chain ( 195) 270 56.0 3.8e-08
NP_524144 (OMIM: 160780) myosin light chain 1/3, s ( 194) 266 55.3 6e-08
NP_004356 (OMIM: 602907) centrin-3 isoform 2 [Homo ( 167) 257 53.7 1.6e-07
NP_524146 (OMIM: 160780) myosin light chain 1/3, s ( 150) 249 52.3 3.8e-07
NP_006088 (OMIM: 609905) myosin regulatory light p ( 172) 239 50.6 1.3e-06
XP_005257448 (OMIM: 160770) PREDICTED: myosin ligh ( 197) 239 50.7 1.4e-06
NP_001002841 (OMIM: 160770) myosin light chain 4 [ ( 197) 239 50.7 1.4e-06
NP_002467 (OMIM: 160770) myosin light chain 4 [Hom ( 197) 239 50.7 1.4e-06
NP_001138416 (OMIM: 609211) myosin regulatory ligh ( 172) 228 48.8 4.9e-06
NP_291024 (OMIM: 609211) myosin regulatory light c ( 172) 228 48.8 4.9e-06
NP_001138417 (OMIM: 609211) myosin regulatory ligh ( 172) 228 48.8 4.9e-06
>>NP_003271 (OMIM: 191040,611879,613243) troponin C, slo (161 aa)
initn: 1058 init1: 1058 opt: 1058 Z-score: 989.6 bits: 189.3 E(85289): 2.2e-48
Smith-Waterman score: 1058; 100.0% identity (100.0% similar) in 161 aa overlap (1-161:1-161)
10 20 30 40 50 60
pF1KE6 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 IDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIM
70 80 90 100 110 120
130 140 150 160
pF1KE6 LQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE
:::::::::::::::::::::::::::::::::::::::::
NP_003 LQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE
130 140 150 160
>>NP_003270 (OMIM: 191039) troponin C, skeletal muscle [ (160 aa)
initn: 849 init1: 610 opt: 673 Z-score: 637.1 bits: 124.1 E(85289): 9.5e-29
Smith-Waterman score: 673; 64.8% identity (84.0% similar) in 162 aa overlap (1-161:1-160)
10 20 30 40 50
pF1KE6 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGC-ISTKELGKVMRMLGQNPTPEELQE
: : : :.::. :::::::.: :. : ::.:::: :::::::.:: :::.
NP_003 MTDQQAEARSYLSEEMIAEFKAAFDMF--DADGGGDISVKELGTVMRMLGQTPTKEELDA
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 MIDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKI
.:.:::::::::.::.:::::::: ::.:.::::::::.. ::.::.::::::: .::
NP_003 IIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAECFRIFDRNADGYIDPEELAE
60 70 80 90 100 110
120 130 140 150 160
pF1KE6 MLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE
...:.:: .:...:: ::::::::::::::.::::..:.::.
NP_003 IFRASGEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMMEGVQ
120 130 140 150 160
>>XP_011527333 (OMIM: 191039) PREDICTED: troponin C, ske (145 aa)
initn: 834 init1: 610 opt: 650 Z-score: 616.5 bits: 120.2 E(85289): 1.3e-27
Smith-Waterman score: 650; 68.8% identity (88.9% similar) in 144 aa overlap (19-161:4-145)
10 20 30 40 50
pF1KE6 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGC-ISTKELGKVMRMLGQNPTPEELQE
:::::::.: :. : ::.:::: :::::::.:: :::.
XP_011 MIAEFKAAFDMF--DADGGGDISVKELGTVMRMLGQTPTKEELDA
10 20 30 40
60 70 80 90 100 110
pF1KE6 MIDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKI
.:.:::::::::.::.:::::::: ::.:.::::::::.. ::.::.::::::: .::
XP_011 IIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAECFRIFDRNADGYIDPEELAE
50 60 70 80 90 100
120 130 140 150 160
pF1KE6 MLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE
...:.:: .:...:: ::::::::::::::.::::..:.::.
XP_011 IFRASGEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMMEGVQ
110 120 130 140
>>NP_005175 (OMIM: 114183) calmodulin isoform 1 [Homo sa (149 aa)
initn: 521 init1: 267 opt: 512 Z-score: 490.0 bits: 96.8 E(85289): 1.5e-20
Smith-Waterman score: 512; 52.0% identity (80.4% similar) in 148 aa overlap (10-157:3-146)
10 20 30 40 50 60
pF1KE6 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEM
.:::::: ::: ::..: . :: :.::::: ::: :::::: :::.:
NP_005 MADQLTEEQIAEFKEAFSLFDKDG-DGTITTKELGTVMRSLGQNPTEAELQDM
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 IDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIM
:.::: ::.::.:: :::.::.: ::: . ::::. . ::.:::...:::. ::. .
NP_005 INEVDADGNGTIDFPEFLTMMARKMKDTD---SEEEIREAFRVFDKDGNGYISAAELRHV
60 70 80 90 100
130 140 150 160
pF1KE6 LQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE
. :: .:.....:.....: ..::...:.::...:
NP_005 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
110 120 130 140
>>NP_008819 (OMIM: 114180,614916,616247) calmodulin [Hom (149 aa)
initn: 521 init1: 267 opt: 512 Z-score: 490.0 bits: 96.8 E(85289): 1.5e-20
Smith-Waterman score: 512; 52.0% identity (80.4% similar) in 148 aa overlap (10-157:3-146)
10 20 30 40 50 60
pF1KE6 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEM
.:::::: ::: ::..: . :: :.::::: ::: :::::: :::.:
NP_008 MADQLTEEQIAEFKEAFSLFDKDG-DGTITTKELGTVMRSLGQNPTEAELQDM
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 IDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIM
:.::: ::.::.:: :::.::.: ::: . ::::. . ::.:::...:::. ::. .
NP_008 INEVDADGNGTIDFPEFLTMMARKMKDTD---SEEEIREAFRVFDKDGNGYISAAELRHV
60 70 80 90 100
130 140 150 160
pF1KE6 LQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE
. :: .:.....:.....: ..::...:.::...:
NP_008 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
110 120 130 140
>>NP_001316851 (OMIM: 114183) calmodulin isoform 1 [Homo (149 aa)
initn: 521 init1: 267 opt: 512 Z-score: 490.0 bits: 96.8 E(85289): 1.5e-20
Smith-Waterman score: 512; 52.0% identity (80.4% similar) in 148 aa overlap (10-157:3-146)
10 20 30 40 50 60
pF1KE6 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEM
.:::::: ::: ::..: . :: :.::::: ::: :::::: :::.:
NP_001 MADQLTEEQIAEFKEAFSLFDKDG-DGTITTKELGTVMRSLGQNPTEAELQDM
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 IDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIM
:.::: ::.::.:: :::.::.: ::: . ::::. . ::.:::...:::. ::. .
NP_001 INEVDADGNGTIDFPEFLTMMARKMKDTD---SEEEIREAFRVFDKDGNGYISAAELRHV
60 70 80 90 100
130 140 150 160
pF1KE6 LQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE
. :: .:.....:.....: ..::...:.::...:
NP_001 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
110 120 130 140
>>NP_001734 (OMIM: 114182,616249) calmodulin isoform 2 [ (149 aa)
initn: 521 init1: 267 opt: 512 Z-score: 490.0 bits: 96.8 E(85289): 1.5e-20
Smith-Waterman score: 512; 52.0% identity (80.4% similar) in 148 aa overlap (10-157:3-146)
10 20 30 40 50 60
pF1KE6 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEM
.:::::: ::: ::..: . :: :.::::: ::: :::::: :::.:
NP_001 MADQLTEEQIAEFKEAFSLFDKDG-DGTITTKELGTVMRSLGQNPTEAELQDM
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 IDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIM
:.::: ::.::.:: :::.::.: ::: . ::::. . ::.:::...:::. ::. .
NP_001 INEVDADGNGTIDFPEFLTMMARKMKDTD---SEEEIREAFRVFDKDGNGYISAAELRHV
60 70 80 90 100
130 140 150 160
pF1KE6 LQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE
. :: .:.....:.....: ..::...:.::...:
NP_001 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
110 120 130 140
>>XP_006720321 (OMIM: 114180,614916,616247) PREDICTED: c (150 aa)
initn: 521 init1: 267 opt: 512 Z-score: 490.0 bits: 96.8 E(85289): 1.5e-20
Smith-Waterman score: 512; 52.0% identity (80.4% similar) in 148 aa overlap (10-157:4-147)
10 20 30 40 50 60
pF1KE6 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEM
.:::::: ::: ::..: . :: :.::::: ::: :::::: :::.:
XP_006 MQADQLTEEQIAEFKEAFSLFDKDG-DGTITTKELGTVMRSLGQNPTEAELQDM
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 IDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIM
:.::: ::.::.:: :::.::.: ::: . ::::. . ::.:::...:::. ::. .
XP_006 INEVDADGNGTIDFPEFLTMMARKMKDTD---SEEEIREAFRVFDKDGNGYISAAELRHV
60 70 80 90 100 110
130 140 150 160
pF1KE6 LQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE
. :: .:.....:.....: ..::...:.::...:
XP_006 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
120 130 140 150
>>NP_001292553 (OMIM: 114182,616249) calmodulin isoform (197 aa)
initn: 521 init1: 267 opt: 512 Z-score: 488.8 bits: 97.0 E(85289): 1.7e-20
Smith-Waterman score: 512; 52.0% identity (80.4% similar) in 148 aa overlap (10-157:51-194)
10 20 30
pF1KE6 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTK
.:::::: ::: ::..: . :: :.::
NP_001 CVVASRKPVALAAWLALYIASHFAQQPCKADQLTEEQIAEFKEAFSLFDKDG-DGTITTK
30 40 50 60 70
40 50 60 70 80 90
pF1KE6 ELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSD
::: ::: :::::: :::.::.::: ::.::.:: :::.::.: ::: . ::::. .
NP_001 ELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTD---SEEEIRE
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE6 LFRMFDKNADGYIDLDELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKG
::.:::...:::. ::. .. :: .:.....:.....: ..::...:.::...:
NP_001 AFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA
140 150 160 170 180 190
160
pF1KE6 VE
NP_001 K
>>NP_005176 (OMIM: 114184) calmodulin-like protein 3 [Ho (149 aa)
initn: 496 init1: 264 opt: 488 Z-score: 468.1 bits: 92.7 E(85289): 2.5e-19
Smith-Waterman score: 488; 47.3% identity (80.4% similar) in 148 aa overlap (10-157:3-146)
10 20 30 40 50 60
pF1KE6 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEM
.:::::: .::: ::..: . ::::.:.::: ::: :::::: ::..:
NP_005 MADQLTEEQVTEFKEAFSLFDKDG-DGCITTRELGTVMRSLGQNPTEAELRDM
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 IDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIM
..:.:.::.::::: ::: ::.: ::: . .:::. . ::.:::...:... ::. .
NP_005 MSEIDRDGNGTVDFPEFLGMMARKMKDTD---NEEEIREAFRVFDKDGNGFVSAAELRHV
60 70 80 90 100
130 140 150 160
pF1KE6 LQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE
. :: .......:... .: ..::...:.::.. .
NP_005 MTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVLVSK
110 120 130 140
161 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 09:32:01 2016 done: Tue Nov 8 09:32:01 2016
Total Scan time: 4.690 Total Display time: -0.040
Function used was FASTA [36.3.4 Apr, 2011]