Result of FASTA (omim) for
pFN21AB6337
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6337, 262 aa
1>>>pF1KB6337 262 - 262 aa - 262 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0588+/-0.00037; mu= 16.0441+/- 0.023
mean_var=69.2820+/-14.150, 0's: 0 Z-trim(113.3): 297 B-trim: 0 in 0/52
Lambda= 0.154086
statistics sampled from 22227 (22542) to 22227 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.264), width: 16
Scan time: 6.610
The best scores are: opt bits E(85289)
NP_006135 (OMIM: 140050) granzyme A precursor [Hom ( 262) 1783 405.4 5.6e-113
NP_002095 (OMIM: 600784) granzyme K precursor [Hom ( 264) 722 169.5 5.6e-42
NP_001919 (OMIM: 134350,613912) complement factor ( 253) 621 147.0 3.1e-35
NP_001304264 (OMIM: 134350,613912) complement fact ( 260) 621 147.0 3.2e-35
NP_004122 (OMIM: 123910) granzyme B isoform 1 prep ( 247) 582 138.4 1.2e-32
NP_219491 (OMIM: 116831) granzyme H isoform 1 prep ( 246) 567 135.0 1.2e-31
NP_001332940 (OMIM: 123910) granzyme B isoform 2 [ ( 235) 565 134.6 1.6e-31
NP_001298111 (OMIM: 606135) kallikrein-14 prepropr ( 267) 559 133.3 4.6e-31
NP_071329 (OMIM: 606135) kallikrein-14 preproprote ( 267) 559 133.3 4.6e-31
NP_009127 (OMIM: 605644) kallikrein-8 isoform 1 pr ( 260) 539 128.8 9.8e-30
NP_653088 (OMIM: 605644) kallikrein-8 isoform 2 pr ( 305) 539 128.9 1.1e-29
NP_001827 (OMIM: 118938) chymase isoform 1 preprop ( 247) 528 126.3 5.1e-29
NP_001639 (OMIM: 176820) prostate-specific antigen ( 261) 507 121.7 1.4e-27
NP_002760 (OMIM: 167800,276000,614044) trypsin-1 p ( 247) 504 121.0 2.1e-27
NP_005308 (OMIM: 600311) granzyme M isoform 1 prep ( 257) 504 121.0 2.1e-27
NP_056411 (OMIM: 605505) kallikrein-13 precursor [ ( 277) 504 121.0 2.3e-27
XP_011514713 (OMIM: 167800,276000,614044) PREDICTE ( 472) 504 121.2 3.4e-27
NP_665901 (OMIM: 605539) kallikrein-12 isoform 2 p ( 248) 499 119.9 4.5e-27
NP_001902 (OMIM: 116830) cathepsin G preproprotein ( 255) 499 119.9 4.6e-27
XP_011534801 (OMIM: 116830) PREDICTED: cathepsin G ( 269) 498 119.7 5.6e-27
NP_001129504 (OMIM: 604434) kallikrein-11 isoform ( 250) 494 118.8 9.7e-27
NP_006844 (OMIM: 604434) kallikrein-11 isoform 1 p ( 250) 494 118.8 9.7e-27
NP_659196 (OMIM: 604434) kallikrein-11 isoform 2 [ ( 282) 494 118.8 1.1e-26
NP_002765 (OMIM: 602652) kallikrein-6 isoform A pr ( 244) 486 117.0 3.3e-26
NP_001012982 (OMIM: 602652) kallikrein-6 isoform A ( 244) 486 117.0 3.3e-26
NP_001264010 (OMIM: 610601) kallikrein-15 isoform ( 255) 485 116.8 3.9e-26
XP_011525387 (OMIM: 610601) PREDICTED: kallikrein- ( 255) 485 116.8 3.9e-26
NP_059979 (OMIM: 610601) kallikrein-15 isoform 4 p ( 256) 485 116.8 4e-26
XP_006723328 (OMIM: 610601) PREDICTED: kallikrein- ( 256) 485 116.8 4e-26
NP_002248 (OMIM: 147910,615953) kallikrein-1 prepr ( 262) 481 115.9 7.5e-26
NP_005542 (OMIM: 147960) kallikrein-2 isoform 1 pr ( 261) 479 115.5 1e-25
NP_004908 (OMIM: 204700,603767) kallikrein-4 isofo ( 254) 477 115.0 1.3e-25
NP_062544 (OMIM: 605539) kallikrein-12 isoform 1 p ( 254) 476 114.8 1.6e-25
XP_011534985 (OMIM: 116831) PREDICTED: granzyme H ( 212) 473 114.1 2.2e-25
NP_036447 (OMIM: 605504) kallikrein-9 precursor [H ( 250) 470 113.5 3.9e-25
NP_001184026 (OMIM: 613578) trypsin-3 isoform 3 pr ( 261) 469 113.2 4.7e-25
NP_002762 (OMIM: 613578) trypsin-3 isoform 2 prepr ( 247) 467 112.8 6.2e-25
NP_001184027 (OMIM: 613578) trypsin-3 isoform 4 pr ( 240) 463 111.9 1.1e-24
NP_031369 (OMIM: 613578) trypsin-3 isoform 1 prepr ( 304) 463 112.0 1.3e-24
XP_011516267 (OMIM: 613578) PREDICTED: trypsin-3 i ( 333) 463 112.0 1.4e-24
NP_002763 (OMIM: 226200,606635) enteropeptidase pr (1019) 466 113.0 2.2e-24
XP_011527961 (OMIM: 226200,606635) PREDICTED: ente (1034) 466 113.0 2.2e-24
XP_011527960 (OMIM: 226200,606635) PREDICTED: ente (1037) 466 113.0 2.2e-24
XP_011527959 (OMIM: 226200,606635) PREDICTED: ente (1049) 466 113.0 2.2e-24
XP_011527956 (OMIM: 226200,606635) PREDICTED: ente (1064) 466 113.0 2.2e-24
XP_011527957 (OMIM: 226200,606635) PREDICTED: ente (1064) 466 113.0 2.2e-24
XP_011527958 (OMIM: 226200,606635) PREDICTED: ente (1064) 466 113.0 2.2e-24
NP_002764 (OMIM: 600823) prostasin preproprotein [ ( 343) 460 111.3 2.3e-24
NP_002761 (OMIM: 167800,601564) trypsin-2 isoform ( 247) 457 110.6 2.9e-24
NP_001182058 (OMIM: 613517,613858) serine protease ( 603) 456 110.6 6.7e-24
>>NP_006135 (OMIM: 140050) granzyme A precursor [Homo sa (262 aa)
initn: 1783 init1: 1783 opt: 1783 Z-score: 2149.4 bits: 405.4 E(85289): 5.6e-113
Smith-Waterman score: 1783; 100.0% identity (100.0% similar) in 262 aa overlap (1-262:1-262)
10 20 30 40 50 60
pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 DRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGP
190 200 210 220 230 240
250 260
pF1KB6 GVYILLSKKHLNWIIMTIKGAV
::::::::::::::::::::::
NP_006 GVYILLSKKHLNWIIMTIKGAV
250 260
>>NP_002095 (OMIM: 600784) granzyme K precursor [Homo sa (264 aa)
initn: 646 init1: 405 opt: 722 Z-score: 874.6 bits: 169.5 E(85289): 5.6e-42
Smith-Waterman score: 722; 45.1% identity (73.8% similar) in 237 aa overlap (25-254:21-254)
10 20 30 40 50
pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVC--EKIIGGNEVTPHSRPYMVLLSLDRKTICAGAL
:: .::::.::.:::::.:. .. . .:.:.:
NP_002 MTKFSSFSLFFLIVGAYMTHVCFNMEIIGGKEVSPHSRPFMASIQYGGHHVCGGVL
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 IAKDWVLTAAHCNL----NKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGD
: .::::::::. .. :.:::::....: .:: . .:: .:. . .:
NP_002 IDPQWVLTAAHCQYRFTKGQSPTVVLGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSND
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 LKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTH-NSASWSDTLREVNITI
. :..: ::.::.: .::. .: ... :: :.:.::: : .: :::::::..:.
NP_002 IMLVKLQTAAKLNKHVKMLHIRSK-TSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 IDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENK
..::.::....:: .: : .:::::. .: .:::.::::.::.:.:::....: : :
NP_002 LSRKLCNSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGHE--
180 190 200 210 220 230
240 250 260
pF1KB6 CGDPRGPGVYILLSKKHLNWIIMTIKGAV
:: ::.: ::.::. .::
NP_002 CGVATKPGIYTLLTKKYQTWIKSNLVPPHTN
240 250 260
>>NP_001919 (OMIM: 134350,613912) complement factor D is (253 aa)
initn: 613 init1: 313 opt: 621 Z-score: 753.5 bits: 147.0 E(85289): 3.1e-35
Smith-Waterman score: 621; 41.3% identity (70.4% similar) in 230 aa overlap (28-254:25-248)
10 20 30 40 50 60
pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIA
.:.:: :. :.::::. ..:. .:.:.:.:
NP_001 MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVA
10 20 30 40 50
70 80 90 100 110
pF1KB6 KDWVLTAAHC---NLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKL
..:::.:::: . . ::.:::::... ::.:... : . :.: .: : . :: :
NP_001 EQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 LQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRK
:::.::: .. : : . :: :::.:.::::: ..... :.:..: . ..::
NP_001 LQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 VCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDP
.:: :.:. . .: ..:: : : ::::.::::.::.: ::..::.. : ::.
NP_001 TCNRRTHH--DGAITERLMCAESNR--RDSCKGDSGGPLVCGGVLEGVVTSG-SRVCGNR
180 190 200 210 220 230
240 250 260
pF1KB6 RGPGVYILLSKKHLNWIIMTIKGAV
. ::.: ... . ::
NP_001 KKPGIYTRVAS-YAAWIDSVLA
240 250
>>NP_001304264 (OMIM: 134350,613912) complement factor D (260 aa)
initn: 613 init1: 313 opt: 621 Z-score: 753.4 bits: 147.0 E(85289): 3.2e-35
Smith-Waterman score: 621; 41.3% identity (70.4% similar) in 230 aa overlap (28-254:32-255)
10 20 30 40 50
pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGA
.:.:: :. :.::::. ..:. .:.:.
NP_001 HSWERLAVLVLLGAAACGEEAWAWAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 LIAKDWVLTAAHC---NLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGD
:.:..:::.:::: . . ::.:::::... ::.:... : . :.: .: : . :
NP_001 LVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 LKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITII
: ::::.::: .. : : . :: :::.:.::::: ..... :.:..: . ..
NP_001 LLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 DRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKC
:: .:: :.:. . .: ..:: : : ::::.::::.::.: ::..::.. : :
NP_001 DRATCNRRTHH--DGAITERLMCAESNR--RDSCKGDSGGPLVCGGVLEGVVTSG-SRVC
190 200 210 220 230
240 250 260
pF1KB6 GDPRGPGVYILLSKKHLNWIIMTIKGAV
:. . ::.: ... . ::
NP_001 GNRKKPGIYTRVAS-YAAWIDSVLA
240 250 260
>>NP_004122 (OMIM: 123910) granzyme B isoform 1 prepropr (247 aa)
initn: 553 init1: 296 opt: 582 Z-score: 706.8 bits: 138.4 E(85289): 1.2e-32
Smith-Waterman score: 582; 42.0% identity (70.8% similar) in 250 aa overlap (14-259:6-245)
10 20 30 40 50
pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSL-DRKTI--CAGA
.....::.:. .::::.:. :::::::. : . :.:.. :.:
NP_004 MQPILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGF
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 LIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKL
:: :.::::::: .. .: ::::.: ..:::.:.. ::. .:.: :.: . .:. :
NP_004 LIRDDFVLTAAHC-WGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIML
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 LQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITII-DR
::: .::: .. : :.::.. .:::: :.:::::.: .. : ::.::..:. ::
NP_004 LQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 KVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGD
: .: :: .. .: . :.:. . . : .::::.::.:. : .:..:.: .: :
NP_004 KCESDLRHY-YDSTIEL---CVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNN--GM
180 190 200 210 220
240 250 260
pF1KB6 PRGPGVYILLSKKHLNWIIMTIKGAV
: : . .:. ..:: :.:
NP_004 P--PRACTKVSS-FVHWIKKTMKRY
230 240
>>NP_219491 (OMIM: 116831) granzyme H isoform 1 prepropr (246 aa)
initn: 512 init1: 242 opt: 567 Z-score: 688.8 bits: 135.0 E(85289): 1.2e-31
Smith-Waterman score: 585; 41.8% identity (69.9% similar) in 249 aa overlap (14-259:6-244)
10 20 30 40 50
pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLS-LDRKTI--CAGA
.....:: : :.::::.:. :::::::.... :..:. :.:
NP_219 MQPFLLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGI
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 LIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKL
:. ::.:::::::. .. .: ::::.: ..: :.:.. ::. .:.: :.: . .:. :
NP_219 LVRKDFVLTAAHCQ-GSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIML
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 LQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRK
::: .::: . : :.::.. .:::: .:.::::: . : . . ::.:: .:.
NP_219 LQLERKAKWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMS-TLATTLQEVLLTVQKDC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 VCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDP
:. : :.. . . .:.:. . . . .::::.::.:. : .:. :.: :: : :
NP_219 QCERLFHGNYSRA---TEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYG--NKKGTP
180 190 200 210 220
240 250 260
pF1KB6 RGPGVYILLSKKHLNWIIMTIKGAV
::::: .:. : :: :.:
NP_219 --PGVYIKVSH-FLPWIKRTMKRL
230 240
>>NP_001332940 (OMIM: 123910) granzyme B isoform 2 [Homo (235 aa)
initn: 540 init1: 296 opt: 565 Z-score: 686.7 bits: 134.6 E(85289): 1.6e-31
Smith-Waterman score: 565; 43.2% identity (70.8% similar) in 236 aa overlap (28-259:8-233)
10 20 30 40 50
pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSL-DRKTI--CAGA
.::::.:. :::::::. : . :.:.. :.:
NP_001 MQTFPSGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGF
10 20 30 40
60 70 80 90 100 110
pF1KB6 LIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKL
:: :.::::::: .. .: ::::.: ..:::.:.. ::. .:.: :.: . .:. :
NP_001 LIRDDFVLTAAHC-WGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIML
50 60 70 80 90
120 130 140 150 160 170
pF1KB6 LQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITII-DR
::: .::: .. : :.::.. .:::: :.:::::.: .. : ::.::..:. ::
NP_001 LQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDR
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB6 KVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGD
: .: :: .. .: . :.:. . . : .::::.::.:. : .:..:.: .: :
NP_001 KCESDLRHY-YDSTIEL---CVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNN--GM
160 170 180 190 200 210
240 250 260
pF1KB6 PRGPGVYILLSKKHLNWIIMTIKGAV
: : . .:. ..:: :.:
NP_001 P--PRACTKVSS-FVHWIKKTMKRY
220 230
>>NP_001298111 (OMIM: 606135) kallikrein-14 preproprotei (267 aa)
initn: 518 init1: 175 opt: 559 Z-score: 678.7 bits: 133.3 E(85289): 4.6e-31
Smith-Waterman score: 559; 37.5% identity (67.6% similar) in 256 aa overlap (7-259:19-265)
10 20 30 40
pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYM--VLL
.: ..:.:.. . .. .:::::. : :.:.. .:
NP_001 MSLRVLGSGTWPSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 SLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCY
. :. .:.:::.. .::.:::::. :: :: :.. : : :.:.. : .. .: :
NP_001 GPRRRFLCGGALLSGQWVITAAHCG-RPILQVALGKHNLRRWEATQQVLRVVRQVTHPNY
70 80 90 100 110
110 120 130 140 150 160
pF1KB6 DPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNS-ASWSDT
. :...:: :::: . :.:.. : ... . ..::: :.:.::: . : . .
NP_001 NSRTHDNDLMLLQLQQPARIGRAVRPIEVTQAC--ASPGTSCRVSGWGTISSPIARYPAS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 LREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGV
:. :::.: .::. ...: .::::: .::.:::.::::.::.:.: ..:.
NP_001 LQCVNINISPDEVCQKAYPRTITP----GMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGL
180 190 200 210 220 230
230 240 250 260
pF1KB6 TSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV
.:.:.: .:. : :::: : : . .:: :..
NP_001 VSWGME-RCALPGYPGVYTNLCK-YRSWIEETMRDK
240 250 260
>>NP_071329 (OMIM: 606135) kallikrein-14 preproprotein [ (267 aa)
initn: 518 init1: 175 opt: 559 Z-score: 678.7 bits: 133.3 E(85289): 4.6e-31
Smith-Waterman score: 559; 37.5% identity (67.6% similar) in 256 aa overlap (7-259:19-265)
10 20 30 40
pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYM--VLL
.: ..:.:.. . .. .:::::. : :.:.. .:
NP_071 MSLRVLGSGTWPSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 SLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCY
. :. .:.:::.. .::.:::::. :: :: :.. : : :.:.. : .. .: :
NP_071 GPRRRFLCGGALLSGQWVITAAHCG-RPILQVALGKHNLRRWEATQQVLRVVRQVTHPNY
70 80 90 100 110
110 120 130 140 150 160
pF1KB6 DPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNS-ASWSDT
. :...:: :::: . :.:.. : ... . ..::: :.:.::: . : . .
NP_071 NSRTHDNDLMLLQLQQPARIGRAVRPIEVTQAC--ASPGTSCRVSGWGTISSPIARYPAS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 LREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGV
:. :::.: .::. ...: .::::: .::.:::.::::.::.:.: ..:.
NP_071 LQCVNINISPDEVCQKAYPRTITP----GMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGL
180 190 200 210 220 230
230 240 250 260
pF1KB6 TSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV
.:.:.: .:. : :::: : : . .:: :..
NP_071 VSWGME-RCALPGYPGVYTNLCK-YRSWIEETMRDK
240 250 260
>>NP_009127 (OMIM: 605644) kallikrein-8 isoform 1 prepro (260 aa)
initn: 354 init1: 206 opt: 539 Z-score: 654.9 bits: 128.8 E(85289): 9.8e-30
Smith-Waterman score: 539; 37.9% identity (65.8% similar) in 240 aa overlap (27-260:31-260)
10 20 30 40 50
pF1KB6 MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAG
.:..::.: :::.:... : .. .:.:
NP_009 MGRPRPRAAKTWMFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 ALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREG---
.:.. .::::::::. : . : :: ::. .. .: . : . .:.:::. . :
NP_009 VLVGGNWVLTAAHCKKPKYT-VRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNH
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 DLKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGR-THNSASWSDTLREVNIT
:: :::: ..:.... : . : . ..:: : :.::: : .. ::: ...
NP_009 DLMLLQLRDQASLGSKVKPISLADHC--TQPGQKCTVSGWGTVTSPRENFPDTLNCAEVK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 IIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLEN
:. .: :.: . : .:::::: .:. :.:.::::.::.:.:...:.::.: .
NP_009 IFPQKKCED----AYPGQITDGMVCAGSSKGA-DTCQGDSGGPLVCDGALQGITSWG-SD
180 190 200 210 220 230
240 250 260
pF1KB6 KCGDPRGPGVYILLSKKHLNWI--IMTIKGAV
:: :::: . . .:.:: :. ::
NP_009 PCGRSDKPGVYTNICR-YLDWIKKIIGSKG
240 250 260
262 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:57:11 2016 done: Sat Nov 5 07:57:12 2016
Total Scan time: 6.610 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]