Result of FASTA (omim) for
pFN21AB7984
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7984, 324 aa
1>>>pF1KB7984 324 - 324 aa - 324 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.1899+/-0.000325; mu= 4.6254+/- 0.021
mean_var=194.1521+/-40.140, 0's: 0 Z-trim(121.6): 289 B-trim: 125 in 2/55
Lambda= 0.092046
statistics sampled from 38187 (38504) to 38187 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.451), width: 16
Scan time: 8.890
The best scores are: opt bits E(85289)
NP_000316 (OMIM: 137600,180500,180550,601542,60422 ( 324) 2186 302.0 1.1e-81
NP_001191326 (OMIM: 137600,180500,180550,601542,60 ( 317) 1744 243.3 4.9e-64
NP_700475 (OMIM: 137600,180500,180550,601542,60422 ( 317) 1744 243.3 4.9e-64
NP_001191327 (OMIM: 137600,180500,180550,601542,60 ( 317) 1744 243.3 4.9e-64
NP_001191328 (OMIM: 137600,180500,180550,601542,60 ( 271) 1731 241.6 1.4e-63
NP_700476 (OMIM: 137600,180500,180550,601542,60422 ( 271) 1731 241.6 1.4e-63
XP_011530329 (OMIM: 137600,180500,180550,601542,60 ( 271) 1731 241.6 1.4e-63
NP_002644 (OMIM: 119800,186550,602149) pituitary h ( 314) 1220 173.8 4.3e-43
NP_005020 (OMIM: 107250,602669,610623) pituitary h ( 302) 1008 145.6 1.2e-34
NP_620689 (OMIM: 300004,300215,300382,300419,30835 ( 562) 387 63.3 1.3e-09
NP_008913 (OMIM: 601527,613456) ALX homeobox prote ( 326) 382 62.5 1.4e-09
XP_011537084 (OMIM: 601527,613456) PREDICTED: ALX ( 231) 377 61.7 1.7e-09
NP_006483 (OMIM: 136760,606014) homeobox protein a ( 343) 353 58.7 2.1e-08
NP_115485 (OMIM: 604529) homeobox protein orthoped ( 325) 351 58.4 2.4e-08
NP_001128726 (OMIM: 167410,268220) paired box prot ( 505) 354 58.9 2.5e-08
NP_039236 (OMIM: 167410,268220) paired box protein ( 518) 354 58.9 2.6e-08
NP_002575 (OMIM: 167410,268220) paired box protein ( 520) 354 58.9 2.6e-08
NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346) 346 57.7 4e-08
NP_068745 (OMIM: 605420,609597,613451,615529) home ( 411) 347 57.9 4.2e-08
NP_852126 (OMIM: 122880,148820,193500,268220,60659 ( 403) 324 54.9 3.4e-07
NP_852125 (OMIM: 122880,148820,193500,268220,60659 ( 407) 324 54.9 3.4e-07
NP_852122 (OMIM: 122880,148820,193500,268220,60659 ( 479) 323 54.8 4.2e-07
NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483) 323 54.8 4.3e-07
NP_852123 (OMIM: 122880,148820,193500,268220,60659 ( 484) 323 54.8 4.3e-07
NP_852124 (OMIM: 122880,148820,193500,268220,60659 ( 505) 323 54.8 4.4e-07
NP_703149 (OMIM: 300154) homeobox protein ESX1 [Ho ( 406) 316 53.8 7.1e-07
NP_001257453 (OMIM: 600037,610125,613986) homeobox ( 289) 309 52.8 1.1e-06
NP_758840 (OMIM: 600037,610125,613986) homeobox pr ( 289) 309 52.8 1.1e-06
NP_001257452 (OMIM: 600037,610125,613986) homeobox ( 289) 309 52.8 1.1e-06
XP_006711451 (OMIM: 167420,202650) PREDICTED: pair ( 198) 303 51.8 1.4e-06
NP_073207 (OMIM: 167420,202650) paired mesoderm ho ( 245) 303 51.9 1.6e-06
NP_008833 (OMIM: 167420,202650) paired mesoderm ho ( 217) 300 51.5 1.9e-06
NP_068374 (OMIM: 600037,610125,613986) homeobox pr ( 297) 300 51.6 2.5e-06
NP_001257454 (OMIM: 600037,610125,613986) homeobox ( 297) 300 51.6 2.5e-06
NP_003915 (OMIM: 209880,603851,613013) paired meso ( 314) 296 51.1 3.7e-06
NP_057391 (OMIM: 604675) paired mesoderm homeobox ( 253) 294 50.7 3.8e-06
NP_671725 (OMIM: 607410) diencephalon/mesencephalo ( 382) 295 51.0 4.7e-06
XP_011538970 (OMIM: 607410) PREDICTED: diencephalo ( 377) 294 50.9 5.1e-06
NP_757379 (OMIM: 607410) diencephalon/mesencephalo ( 377) 294 50.9 5.1e-06
XP_016855778 (OMIM: 607410) PREDICTED: diencephalo ( 377) 294 50.9 5.1e-06
NP_001263380 (OMIM: 606701) dorsal root ganglia ho ( 263) 291 50.3 5.1e-06
XP_016883326 (OMIM: 122000,148300,605020,614195) P ( 280) 288 50.0 7.1e-06
NP_878314 (OMIM: 142993,610092,610093) visual syst ( 361) 290 50.3 7.2e-06
NP_001243201 (OMIM: 122000,148300,605020,614195) v ( 301) 288 50.0 7.5e-06
XP_016870292 (OMIM: 604675) PREDICTED: paired meso ( 193) 284 49.3 7.8e-06
NP_055403 (OMIM: 122000,148300,605020,614195) visu ( 365) 288 50.0 8.7e-06
NP_055377 (OMIM: 600036) homeobox protein OTX1 [Ho ( 354) 285 49.6 1.1e-05
NP_001186699 (OMIM: 600036) homeobox protein OTX1 ( 354) 285 49.6 1.1e-05
NP_001297089 (OMIM: 106210,120430,136520,148190,16 ( 286) 283 49.3 1.1e-05
NP_001297090 (OMIM: 106210,120430,136520,148190,16 ( 286) 283 49.3 1.1e-05
>>NP_000316 (OMIM: 137600,180500,180550,601542,604229) p (324 aa)
initn: 2186 init1: 2186 opt: 2186 Z-score: 1587.7 bits: 302.0 E(85289): 1.1e-81
Smith-Waterman score: 2186; 100.0% identity (100.0% similar) in 324 aa overlap (1-324:1-324)
10 20 30 40 50 60
pF1KB7 MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 DTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 TREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 YSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSS
250 260 270 280 290 300
310 320
pF1KB7 FGYASVQNPASNLSACQYAVDRPV
::::::::::::::::::::::::
NP_000 FGYASVQNPASNLSACQYAVDRPV
310 320
>>NP_001191326 (OMIM: 137600,180500,180550,601542,604229 (317 aa)
initn: 1742 init1: 1742 opt: 1744 Z-score: 1270.7 bits: 243.3 E(85289): 4.9e-64
Smith-Waterman score: 1744; 93.9% identity (95.7% similar) in 279 aa overlap (48-324:39-317)
20 30 40 50 60 70
pF1KB7 KLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTIS--DTSSPEAAEKDKSQQ
:: . : :. . . . : : :::::::
NP_001 VSACVQLGVQPAAVECLFSKDSEIKKVEFTDSPESRKEAASSKFFPRQHPGANEKDKSQQ
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB7 GKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB7 VRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSAS
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB7 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB7 SSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSA
250 260 270 280 290 300
320
pF1KB7 CQYAVDRPV
:::::::::
NP_001 CQYAVDRPV
310
>>NP_700475 (OMIM: 137600,180500,180550,601542,604229) p (317 aa)
initn: 1742 init1: 1742 opt: 1744 Z-score: 1270.7 bits: 243.3 E(85289): 4.9e-64
Smith-Waterman score: 1744; 93.9% identity (95.7% similar) in 279 aa overlap (48-324:39-317)
20 30 40 50 60 70
pF1KB7 KLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTIS--DTSSPEAAEKDKSQQ
:: . : :. . . . : : :::::::
NP_700 VSACVQLGVQPAAVECLFSKDSEIKKVEFTDSPESRKEAASSKFFPRQHPGANEKDKSQQ
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB7 GKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_700 GKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB7 VRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_700 VRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSAS
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB7 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_700 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB7 SSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_700 SSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSA
250 260 270 280 290 300
320
pF1KB7 CQYAVDRPV
:::::::::
NP_700 CQYAVDRPV
310
>>NP_001191327 (OMIM: 137600,180500,180550,601542,604229 (317 aa)
initn: 1742 init1: 1742 opt: 1744 Z-score: 1270.7 bits: 243.3 E(85289): 4.9e-64
Smith-Waterman score: 1744; 93.9% identity (95.7% similar) in 279 aa overlap (48-324:39-317)
20 30 40 50 60 70
pF1KB7 KLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTIS--DTSSPEAAEKDKSQQ
:: . : :. . . . : : :::::::
NP_001 VSACVQLGVQPAAVECLFSKDSEIKKVEFTDSPESRKEAASSKFFPRQHPGANEKDKSQQ
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB7 GKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB7 VRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSAS
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB7 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB7 SSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSA
250 260 270 280 290 300
320
pF1KB7 CQYAVDRPV
:::::::::
NP_001 CQYAVDRPV
310
>>NP_001191328 (OMIM: 137600,180500,180550,601542,604229 (271 aa)
initn: 1731 init1: 1731 opt: 1731 Z-score: 1262.3 bits: 241.6 E(85289): 1.4e-63
Smith-Waterman score: 1731; 100.0% identity (100.0% similar) in 256 aa overlap (69-324:16-271)
40 50 60 70 80 90
pF1KB7 LAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTH
::::::::::::::::::::::::::::::
NP_001 METNCRKLVSACVQLEKDKSQQGKNEDVGAEDPSKKKRQRRQRTH
10 20 30 40
100 110 120 130 140 150
pF1KB7 FTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAEL
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB7 CKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMF
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB7 SPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY
170 180 190 200 210 220
280 290 300 310 320
pF1KB7 VYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
230 240 250 260 270
>>NP_700476 (OMIM: 137600,180500,180550,601542,604229) p (271 aa)
initn: 1731 init1: 1731 opt: 1731 Z-score: 1262.3 bits: 241.6 E(85289): 1.4e-63
Smith-Waterman score: 1731; 100.0% identity (100.0% similar) in 256 aa overlap (69-324:16-271)
40 50 60 70 80 90
pF1KB7 LAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTH
::::::::::::::::::::::::::::::
NP_700 METNCRKLVSACVQLEKDKSQQGKNEDVGAEDPSKKKRQRRQRTH
10 20 30 40
100 110 120 130 140 150
pF1KB7 FTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_700 FTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAEL
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB7 CKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_700 CKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMF
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB7 SPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_700 SPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY
170 180 190 200 210 220
280 290 300 310 320
pF1KB7 VYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
::::::::::::::::::::::::::::::::::::::::::::::
NP_700 VYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
230 240 250 260 270
>>XP_011530329 (OMIM: 137600,180500,180550,601542,604229 (271 aa)
initn: 1731 init1: 1731 opt: 1731 Z-score: 1262.3 bits: 241.6 E(85289): 1.4e-63
Smith-Waterman score: 1731; 100.0% identity (100.0% similar) in 256 aa overlap (69-324:16-271)
40 50 60 70 80 90
pF1KB7 LAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTH
::::::::::::::::::::::::::::::
XP_011 METNCRKLVSACVQLEKDKSQQGKNEDVGAEDPSKKKRQRRQRTH
10 20 30 40
100 110 120 130 140 150
pF1KB7 FTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAEL
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB7 CKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMF
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB7 SPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY
170 180 190 200 210 220
280 290 300 310 320
pF1KB7 VYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
230 240 250 260 270
>>NP_002644 (OMIM: 119800,186550,602149) pituitary homeo (314 aa)
initn: 1148 init1: 595 opt: 1220 Z-score: 894.7 bits: 173.8 E(85289): 4.3e-43
Smith-Waterman score: 1228; 62.1% identity (78.2% similar) in 330 aa overlap (1-318:1-312)
10 20 30 40 50
pF1KB7 MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLA-PGQPRSLDSSKHRLEVHTI
:. .:: . ::. : . :. .. : :: :..:: . :: ..
NP_002 MDAFKGGMSLERLPEGLRPPPPP------PHDMGPAFHLARPADPR------EPLE-NSA
10 20 30 40
60 70 80 90 100 110
pF1KB7 SDTSSPEAAEKDKSQQGKN-EDVGA--------EDPSKKKRQRRQRTHFTSQQLQELEAT
:..:. : ::... . :. :: :: .::.:::.:::::::::::::::::::
NP_002 SESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEAT
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 FQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGL
:::::::::: :::::::::::: ::::::::::::::::::::: .:::.:. :::.::
NP_002 FQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGL
110 120 130 140 150 160
180 190 200 210 220
pF1KB7 MQPYDDMYP-GYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSM
.:::.:.: ::::::::::.:. : :::::: :::::. ::::::::: :.:::::.:
NP_002 VQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMS--PLSSQSMFSAPSSISSMTM
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB7 SSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY-VYRDTCNSSL
::: :.:: :.:.:. :::.:::.. :::::. ::::. :. :: ::::::::::
NP_002 PSSMGPGAVPGMPNSG---LNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSL
230 240 250 260 270 280
290 300 310 320
pF1KB7 ASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
::::::.::::::::...:.:::.:.::::
NP_002 ASLRLKSKQHSSFGYGGLQGPASGLNACQYNS
290 300 310
>>NP_005020 (OMIM: 107250,602669,610623) pituitary homeo (302 aa)
initn: 1012 init1: 712 opt: 1008 Z-score: 742.7 bits: 145.6 E(85289): 1.2e-34
Smith-Waterman score: 1013; 56.9% identity (77.6% similar) in 304 aa overlap (47-324:6-302)
20 30 40 50 60 70
pF1KB7 TKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQG
:. .. : . ..::...:. ... .:
NP_005 MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGCKG
10 20 30
80 90 100 110 120
pF1KB7 K----NEDVGA-------EDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEI
. .: ..: :: : ::.::::::::::::::::::::::::::::::::::
NP_005 QEHSDSEKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEI
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 AVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNN
:::::::::::::::::::::::::::.:::::::..:. ..::. ::...::::::.:
NP_005 AVWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 WAAKGLTSASLSTKSFPF-FNSMNVNPLSSQSMFSPPNSIS-SMSMSSSMVPSAVTGVPG
: :.: . :..:.::: :::.::.::.:: .::::.::. :: :.. .:..: : ::
NP_005 WPPKAL-APPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPG-PG
160 170 180 190 200 210
250 260 270 280 290
pF1KB7 SSLNSLNNLNNLSSPSLN-SAVPTPA--CPYAPP--------TPPYVYRDTCNSSLASLR
. :..:.. . :.: .:: . : :::: . :::::: :::::::::
NP_005 A----LQGLGG-GPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLR
220 230 240 250 260
300 310 320
pF1KB7 LKAKQHSSFGYASVQNP--ASNLSACQYAVDRPV
::::::.::.: .:..: :.::: :::::.:::
NP_005 LKAKQHASFSYPAVHGPPPAANLSPCQYAVERPV
270 280 290 300
>>NP_620689 (OMIM: 300004,300215,300382,300419,308350,30 (562 aa)
initn: 340 init1: 288 opt: 387 Z-score: 293.4 bits: 63.3 E(85289): 1.3e-09
Smith-Waterman score: 387; 35.4% identity (61.0% similar) in 254 aa overlap (65-300:299-544)
40 50 60 70 80 90
pF1KB7 MASVLAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQGKNEDVGA--EDPSKKKRQ
:: :: .... ..:. :. :..:
NP_620 AATGAVAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQ
270 280 290 300 310 320
100 110 120 130 140 150
pF1KB7 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER
:: :: ::: ::.::: .::...:::. ::::.:. .::::::.:::.::::::::::.
NP_620 RRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREK
330 340 350 360 370 380
160 170 180 190 200
pF1KB7 NQQAELCKNGF---GP-QFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKS-FPFFNSM
:. :. :: . . ..:: : : .. .. :.:. .. . :: :.
NP_620 AG-AQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFP---SL
390 400 410 420 430 440
210 220 230 240 250 260
pF1KB7 NVNPLSSQSMFSPPNSISSMSMSSSMV------PSAVTGVPGSSLNSLNNLNNLSSPSLN
: .: :. :: : . ...:. . :. .. . : .... :.. :. .
NP_620 PPPP-GSASL--PP-SGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAAL
450 460 470 480 490 500
270 280 290 300 310
pF1KB7 SAVPTPACPYAPPT-----PPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSAC
:::: : . : . : ::.:.::::::.:..
NP_620 LRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKE
510 520 530 540 550 560
320
pF1KB7 QYAVDRPV
NP_620 VC
324 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 10:22:25 2016 done: Sat Nov 5 10:22:27 2016
Total Scan time: 8.890 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]