Result of FASTA (omim) for
pFN21AB4740
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4740, 870 aa
1>>>pF1KB4740 870 - 870 aa - 870 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.5577+/-0.000498; mu= -9.3763+/- 0.031
mean_var=318.5155+/-64.991, 0's: 0 Z-trim(118.2): 276 B-trim: 0 in 0/55
Lambda= 0.071864
statistics sampled from 30552 (30841) to 30552 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.362), width: 16
Scan time: 14.120
The best scores are: opt bits E(85289)
XP_016878370 (OMIM: 602308) PREDICTED: NEDD4-like ( 870) 5965 633.1 1.7e-180
NP_008945 (OMIM: 602308) NEDD4-like E3 ubiquitin-p ( 870) 5965 633.1 1.7e-180
XP_016878369 (OMIM: 602308) PREDICTED: NEDD4-like ( 870) 5965 633.1 1.7e-180
NP_001257383 (OMIM: 602308) NEDD4-like E3 ubiquiti ( 870) 5965 633.1 1.7e-180
XP_011521125 (OMIM: 602308) PREDICTED: NEDD4-like ( 870) 5965 633.1 1.7e-180
XP_011521127 (OMIM: 602308) PREDICTED: NEDD4-like ( 870) 5965 633.1 1.7e-180
XP_016878368 (OMIM: 602308) PREDICTED: NEDD4-like ( 870) 5965 633.1 1.7e-180
XP_011521128 (OMIM: 602308) PREDICTED: NEDD4-like ( 754) 5232 557.1 1.1e-157
NP_001257382 (OMIM: 602308) NEDD4-like E3 ubiquiti ( 754) 5232 557.1 1.1e-157
XP_016868485 (OMIM: 602307) PREDICTED: NEDD4-like ( 743) 3345 361.5 8.6e-99
XP_016868484 (OMIM: 602307) PREDICTED: NEDD4-like ( 743) 3345 361.5 8.6e-99
XP_005250818 (OMIM: 602307) PREDICTED: NEDD4-like ( 921) 3345 361.5 1e-98
XP_016868482 (OMIM: 602307) PREDICTED: NEDD4-like ( 921) 3345 361.5 1e-98
XP_005250817 (OMIM: 602307) PREDICTED: NEDD4-like ( 922) 3345 361.5 1e-98
NP_008944 (OMIM: 602307) NEDD4-like E3 ubiquitin-p ( 922) 3345 361.5 1e-98
NP_113671 (OMIM: 606409,613385) E3 ubiquitin-prote ( 862) 3296 356.4 3.3e-97
NP_001311127 (OMIM: 606409,613385) E3 ubiquitin-pr ( 862) 3296 356.4 3.3e-97
XP_016883579 (OMIM: 606409,613385) PREDICTED: E3 u ( 900) 3267 353.4 2.7e-96
NP_001244067 (OMIM: 606409,613385) E3 ubiquitin-pr ( 752) 3143 340.5 1.7e-92
XP_016883580 (OMIM: 606409,613385) PREDICTED: E3 u ( 752) 3143 340.5 1.7e-92
NP_001311126 (OMIM: 606409,613385) E3 ubiquitin-pr ( 903) 3101 336.2 4.2e-91
NP_001244066 (OMIM: 606409,613385) E3 ubiquitin-pr ( 903) 3101 336.2 4.2e-91
XP_016883578 (OMIM: 606409,613385) PREDICTED: E3 u ( 903) 3101 336.2 4.2e-91
XP_011527381 (OMIM: 606409,613385) PREDICTED: E3 u ( 692) 3093 335.3 5.9e-91
XP_005260627 (OMIM: 606409,613385) PREDICTED: E3 u ( 692) 3093 335.3 5.9e-91
NP_955456 (OMIM: 602308) NEDD4-like E3 ubiquitin-p ( 431) 2989 324.4 7e-88
NP_001257384 (OMIM: 602308) NEDD4-like E3 ubiquiti ( 335) 2216 244.2 7.6e-64
XP_016868486 (OMIM: 602307) PREDICTED: NEDD4-like ( 719) 2080 230.3 2.5e-59
XP_011515104 (OMIM: 602307) PREDICTED: NEDD4-like ( 898) 2080 230.3 3e-59
XP_016868483 (OMIM: 602307) PREDICTED: NEDD4-like ( 898) 2080 230.3 3e-59
NP_001316141 (OMIM: 602278) E3 ubiquitin-protein l ( 753) 1501 170.3 3.1e-41
XP_011519929 (OMIM: 602278) PREDICTED: E3 ubiquiti ( 827) 1501 170.3 3.3e-41
XP_011519928 (OMIM: 602278) PREDICTED: E3 ubiquiti ( 849) 1501 170.3 3.4e-41
XP_011519927 (OMIM: 602278) PREDICTED: E3 ubiquiti ( 849) 1501 170.3 3.4e-41
XP_011519926 (OMIM: 602278) PREDICTED: E3 ubiquiti ( 875) 1501 170.3 3.5e-41
NP_006145 (OMIM: 602278) E3 ubiquitin-protein liga ( 900) 1501 170.3 3.6e-41
NP_940682 (OMIM: 602278) E3 ubiquitin-protein liga (1247) 1501 170.4 4.7e-41
NP_001271269 (OMIM: 602278) E3 ubiquitin-protein l (1302) 1501 170.4 4.9e-41
NP_001271268 (OMIM: 602278) E3 ubiquitin-protein l (1303) 1501 170.4 4.9e-41
NP_001271267 (OMIM: 602278) E3 ubiquitin-protein l (1319) 1501 170.4 4.9e-41
NP_001230889 (OMIM: 606384) E3 ubiquitin-protein l ( 911) 1481 168.2 1.5e-40
XP_016881170 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 684) 1477 167.8 1.6e-40
XP_016881169 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 750) 1477 167.8 1.7e-40
XP_006722488 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 772) 1477 167.8 1.8e-40
NP_001138443 (OMIM: 606384) E3 ubiquitin-protein l ( 834) 1477 167.8 1.9e-40
NP_001138442 (OMIM: 606384) E3 ubiquitin-protein l ( 834) 1477 167.8 1.9e-40
XP_016881166 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 838) 1477 167.8 1.9e-40
XP_016881168 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 854) 1477 167.8 1.9e-40
NP_001138437 (OMIM: 606384) E3 ubiquitin-protein l ( 854) 1477 167.8 1.9e-40
NP_001138436 (OMIM: 606384) E3 ubiquitin-protein l ( 854) 1477 167.8 1.9e-40
>>XP_016878370 (OMIM: 602308) PREDICTED: NEDD4-like E3 u (870 aa)
initn: 5965 init1: 5965 opt: 5965 Z-score: 3361.7 bits: 633.1 E(85289): 1.7e-180
Smith-Waterman score: 5965; 100.0% identity (100.0% similar) in 870 aa overlap (1-870:1-870)
10 20 30 40 50 60
pF1KB4 MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
790 800 810 820 830 840
850 860 870
pF1KB4 RLDLPPYKSYEQLREKLLYAIEETEGFGQE
::::::::::::::::::::::::::::::
XP_016 RLDLPPYKSYEQLREKLLYAIEETEGFGQE
850 860 870
>>NP_008945 (OMIM: 602308) NEDD4-like E3 ubiquitin-prote (870 aa)
initn: 5965 init1: 5965 opt: 5965 Z-score: 3361.7 bits: 633.1 E(85289): 1.7e-180
Smith-Waterman score: 5965; 100.0% identity (100.0% similar) in 870 aa overlap (1-870:1-870)
10 20 30 40 50 60
pF1KB4 MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
790 800 810 820 830 840
850 860 870
pF1KB4 RLDLPPYKSYEQLREKLLYAIEETEGFGQE
::::::::::::::::::::::::::::::
NP_008 RLDLPPYKSYEQLREKLLYAIEETEGFGQE
850 860 870
>>XP_016878369 (OMIM: 602308) PREDICTED: NEDD4-like E3 u (870 aa)
initn: 5965 init1: 5965 opt: 5965 Z-score: 3361.7 bits: 633.1 E(85289): 1.7e-180
Smith-Waterman score: 5965; 100.0% identity (100.0% similar) in 870 aa overlap (1-870:1-870)
10 20 30 40 50 60
pF1KB4 MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
790 800 810 820 830 840
850 860 870
pF1KB4 RLDLPPYKSYEQLREKLLYAIEETEGFGQE
::::::::::::::::::::::::::::::
XP_016 RLDLPPYKSYEQLREKLLYAIEETEGFGQE
850 860 870
>>NP_001257383 (OMIM: 602308) NEDD4-like E3 ubiquitin-pr (870 aa)
initn: 5965 init1: 5965 opt: 5965 Z-score: 3361.7 bits: 633.1 E(85289): 1.7e-180
Smith-Waterman score: 5965; 100.0% identity (100.0% similar) in 870 aa overlap (1-870:1-870)
10 20 30 40 50 60
pF1KB4 MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
790 800 810 820 830 840
850 860 870
pF1KB4 RLDLPPYKSYEQLREKLLYAIEETEGFGQE
::::::::::::::::::::::::::::::
NP_001 RLDLPPYKSYEQLREKLLYAIEETEGFGQE
850 860 870
>>XP_011521125 (OMIM: 602308) PREDICTED: NEDD4-like E3 u (870 aa)
initn: 5965 init1: 5965 opt: 5965 Z-score: 3361.7 bits: 633.1 E(85289): 1.7e-180
Smith-Waterman score: 5965; 100.0% identity (100.0% similar) in 870 aa overlap (1-870:1-870)
10 20 30 40 50 60
pF1KB4 MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
790 800 810 820 830 840
850 860 870
pF1KB4 RLDLPPYKSYEQLREKLLYAIEETEGFGQE
::::::::::::::::::::::::::::::
XP_011 RLDLPPYKSYEQLREKLLYAIEETEGFGQE
850 860 870
>>XP_011521127 (OMIM: 602308) PREDICTED: NEDD4-like E3 u (870 aa)
initn: 5965 init1: 5965 opt: 5965 Z-score: 3361.7 bits: 633.1 E(85289): 1.7e-180
Smith-Waterman score: 5965; 100.0% identity (100.0% similar) in 870 aa overlap (1-870:1-870)
10 20 30 40 50 60
pF1KB4 MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
790 800 810 820 830 840
850 860 870
pF1KB4 RLDLPPYKSYEQLREKLLYAIEETEGFGQE
::::::::::::::::::::::::::::::
XP_011 RLDLPPYKSYEQLREKLLYAIEETEGFGQE
850 860 870
>>XP_016878368 (OMIM: 602308) PREDICTED: NEDD4-like E3 u (870 aa)
initn: 5965 init1: 5965 opt: 5965 Z-score: 3361.7 bits: 633.1 E(85289): 1.7e-180
Smith-Waterman score: 5965; 100.0% identity (100.0% similar) in 870 aa overlap (1-870:1-870)
10 20 30 40 50 60
pF1KB4 MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
790 800 810 820 830 840
850 860 870
pF1KB4 RLDLPPYKSYEQLREKLLYAIEETEGFGQE
::::::::::::::::::::::::::::::
XP_016 RLDLPPYKSYEQLREKLLYAIEETEGFGQE
850 860 870
>>XP_011521128 (OMIM: 602308) PREDICTED: NEDD4-like E3 u (754 aa)
initn: 5232 init1: 5232 opt: 5232 Z-score: 2951.9 bits: 557.1 E(85289): 1.1e-157
Smith-Waterman score: 5232; 100.0% identity (100.0% similar) in 754 aa overlap (117-870:1-754)
90 100 110 120 130 140
pF1KB4 SCHTLRNELLGTASVNLSNVLKNNGGKMENMQLTLNLQTENKGSVVSGGELTIFLDGPTV
::::::::::::::::::::::::::::::
XP_011 MQLTLNLQTENKGSVVSGGELTIFLDGPTV
10 20 30
150 160 170 180 190 200
pF1KB4 DLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQPPSTNCFGGRSRTHRHSGASARTTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQPPSTNCFGGRSRTHRHSGASARTTPA
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB4 TGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPN
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB4 PNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPDALPAGWEQRELPNGRVYYVDHNTKTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPDALPAGWEQRELPNGRVYYVDHNTKTT
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB4 TWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRNQLQGAMQHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRNQLQGAMQHF
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB4 SQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRVYYVNHNTRTTQWEDPRTQGMIQEPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRVYYVNHNTRTTQWEDPRTQGMIQEPAL
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB4 PPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQGSPGAYDRSFRWKYHQFRFLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQGSPGAYDRSFRWKYHQFRFLC
340 350 360 370 380 390
510 520 530 540 550 560
pF1KB4 HSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFL
400 410 420 430 440 450
570 580 590 600 610 620
pF1KB4 LSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGF
460 470 480 490 500 510
630 640 650 660 670 680
pF1KB4 TLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEILGKVTTHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEILGKVTTHE
520 530 540 550 560 570
690 700 710 720 730 740
pF1KB4 LKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELE
580 590 600 610 620 630
750 760 770 780 790 800
pF1KB4 LMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPV
640 650 660 670 680 690
810 820 830 840 850 860
pF1KB4 GGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEETEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEETEG
700 710 720 730 740 750
870
pF1KB4 FGQE
::::
XP_011 FGQE
>>NP_001257382 (OMIM: 602308) NEDD4-like E3 ubiquitin-pr (754 aa)
initn: 5232 init1: 5232 opt: 5232 Z-score: 2951.9 bits: 557.1 E(85289): 1.1e-157
Smith-Waterman score: 5232; 100.0% identity (100.0% similar) in 754 aa overlap (117-870:1-754)
90 100 110 120 130 140
pF1KB4 SCHTLRNELLGTASVNLSNVLKNNGGKMENMQLTLNLQTENKGSVVSGGELTIFLDGPTV
::::::::::::::::::::::::::::::
NP_001 MQLTLNLQTENKGSVVSGGELTIFLDGPTV
10 20 30
150 160 170 180 190 200
pF1KB4 DLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQPPSTNCFGGRSRTHRHSGASARTTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQPPSTNCFGGRSRTHRHSGASARTTPA
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB4 TGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPN
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB4 PNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPDALPAGWEQRELPNGRVYYVDHNTKTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPDALPAGWEQRELPNGRVYYVDHNTKTT
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB4 TWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRNQLQGAMQHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRNQLQGAMQHF
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB4 SQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRVYYVNHNTRTTQWEDPRTQGMIQEPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRVYYVNHNTRTTQWEDPRTQGMIQEPAL
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB4 PPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQGSPGAYDRSFRWKYHQFRFLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQGSPGAYDRSFRWKYHQFRFLC
340 350 360 370 380 390
510 520 530 540 550 560
pF1KB4 HSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFL
400 410 420 430 440 450
570 580 590 600 610 620
pF1KB4 LSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGF
460 470 480 490 500 510
630 640 650 660 670 680
pF1KB4 TLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEILGKVTTHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEILGKVTTHE
520 530 540 550 560 570
690 700 710 720 730 740
pF1KB4 LKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELE
580 590 600 610 620 630
750 760 770 780 790 800
pF1KB4 LMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPV
640 650 660 670 680 690
810 820 830 840 850 860
pF1KB4 GGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEETEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEETEG
700 710 720 730 740 750
870
pF1KB4 FGQE
::::
NP_001 FGQE
>>XP_016868485 (OMIM: 602307) PREDICTED: NEDD4-like E3 u (743 aa)
initn: 2834 init1: 2651 opt: 3345 Z-score: 1894.6 bits: 361.5 E(85289): 8.6e-99
Smith-Waterman score: 3345; 66.3% identity (83.2% similar) in 738 aa overlap (144-870:15-743)
120 130 140 150 160 170
pF1KB4 MENMQLTLNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAV
:: : . : ...:.. :: :. .:.
XP_016 MLAVEGTNGIDNHVPTSTLVQNSCCSYVVNGDNTPSSPSQ-VAA
10 20 30 40
180 190 200 210 220
pF1KB4 APENRHQP------PSTNCFGGRSRTHRHS-GASARTTPATGEQSPGARSRHRQPVKNSG
:.: : :. . .:.: . . .::. ::...:.. . . :..
XP_016 RPKNTPAPKPLASEPADDTVNGESSSFAPTDNASVTGTPVVSEENALSPNCTSTTVEDPP
50 60 70 80 90 100
230 240 250 260 270 280
pF1KB4 HSGLANGTVNDEPTTATDPE-EPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPS
. . ... :.: .:. : : . .. : : : ..: :. .. .
XP_016 VQEILTSSENNECIPSTSAELESEARSILEPD------TSNSRSSS-AFEAAKSRQPDGC
110 120 130 140 150
290 300 310 320 330 340
pF1KB4 TSGTQQLPAAAQAPDALPAGWEQRELPNGRVYYVDHNTKTTTWERP--LPPGWEKRTDPR
. ..: . :.. ..::.:::::. :.::.:::::::.::::::: ::::::.:.: :
XP_016 MDPVRQQSGNANT-ETLPSGWEQRKDPHGRTYYVDHNTRTTTWERPQPLPPGWERRVDDR
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB4 GRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDP
: :::::::::::::::: : :::.:::::::::::::::.:.::.::..: ....::
XP_016 RRVYYVDHNTRTTTWQRPTMESVRNFEQWQSQRNQLQGAMQQFNQRYLYSASMLAAENDP
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB4 LGPLPPGWEKRQDN-GRVYYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYF
:::::::::: :. :::.:::::.:::::::::::. .: :: :::..:: ::::::
XP_016 YGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPRTQGLQNEEPLPEGWEIRYTREGVRYF
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB4 VDHNTRTTTFKDPRPGFESGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQ
:::::::::::::: : : :: : ::.:.:::: .::.::.::::::::::.::::
XP_016 VDHNTRTTTFKDPRNGKSSVTKGGPQIAYERGFRWKLAHFRYLCQSNALPSHVKINVSRQ
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB4 TLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYA
::::::::::: .::::::::::.:.::::::::::.:::::::::::::::::::::::
XP_016 TLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYA
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB4 GKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLK
:::::::::::::.::::::.:: ::::::::::.:::::::::.::::::::.:. :.:
XP_016 GKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIK
460 470 480 490 500 510
650 660 670 680 690 700
pF1KB4 DLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKE
:::::: :::::..::..::.::::::.:: :::::::::.:.:: :: .: ::::::.
XP_016 DLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKD
520 530 540 550 560 570
710 720 730 740 750 760
pF1KB4 EYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQK
::: :.:.:::.:::.:::::::::::::.::.::.::::::::.:::::::.:..:::.
XP_016 EYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQR
580 590 600 610 620 630
770 780 790 800 810 820
pF1KB4 STIYRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFC
.:.:::::.::::: :::: ::: ::: :.:::::::::::::.::::::.:::::::::
XP_016 NTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFC
640 650 660 670 680 690
830 840 850 860 870
pF1KB4 IDKVGKETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEETEGFGQE
:.::::.::::::::::::::::::::::::.::::.:::::::::::
XP_016 IEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
700 710 720 730 740
870 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 09:18:06 2016 done: Sat Nov 5 09:18:08 2016
Total Scan time: 14.120 Total Display time: 0.310
Function used was FASTA [36.3.4 Apr, 2011]