FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1123, 456 aa
  1>>>pF1KE1123 456 - 456 aa - 456 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.9487+/-0.00111; mu= 14.4354+/- 0.066
 mean_var=79.1151+/-15.354, 0's: 0 Z-trim(103.4): 55  B-trim: 0 in 0/50
 Lambda= 0.144193
 statistics sampled from 7338 (7379) to 7338 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.588), E-opt: 0.2 (0.227), width:  16
 Scan time:  2.670

The best scores are:                                      opt bits E(32554)
CCDS3047.1 RUVBL1 gene_id:8607|Hs108|chr3          ( 456) 2903 614.0  1e-175
CCDS82833.1 RUVBL1 gene_id:8607|Hs108|chr3         ( 315) 2034 433.1  2e-121
CCDS42588.1 RUVBL2 gene_id:10856|Hs108|chr19       ( 463)  747 165.5 1.1e-40


>>CCDS3047.1 RUVBL1 gene_id:8607|Hs108|chr3               (456 aa)
 initn: 2903 init1: 2903 opt: 2903  Z-score: 3268.1  bits: 614.0 E(32554): 1e-175
Smith-Waterman score: 2903; 100.0% identity (100.0% similar) in 456 aa overlap (1-456:1-456)

               10        20        30        40        50        60
pF1KE1 MKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 MKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 MAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 MAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 GLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 QKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 QKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 HDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 HDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVLF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 VDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 VDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 IRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 IRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKIN
              370       380       390       400       410       420

              430       440       450      
pF1KE1 GKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK
       ::::::::::::::::::::::::::::::::::::
CCDS30 GKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK
              430       440       450      

>>CCDS82833.1 RUVBL1 gene_id:8607|Hs108|chr3              (315 aa)
 initn: 2034 init1: 2034 opt: 2034  Z-score: 2293.6  bits: 433.1 E(32554): 2e-121
Smith-Waterman score: 2034; 99.7% identity (100.0% similar) in 314 aa overlap (61-374:1-314)

               40        50        60        70        80        90
pF1KE1 LAKQAASGLVGQENAREACGVIVELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSK
                                     ::::::::::::::::::::::::::::::
CCDS82                               MAGRAVLLAGPPGTGKTALALAIAQELGSK
                                             10        20        30

              100       110       120       130       140       150
pF1KE1 VPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 VPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGY
               40        50        60        70        80        90

              160       170       180       190       200       210
pF1KE1 GKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 GKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYA
              100       110       120       130       140       150

              220       230       240       250       260       270
pF1KE1 TEFDLEAEEYVPLPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TEFDLEAEEYVPLPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTE
              160       170       180       190       200       210

              280       290       300       310       320       330
pF1KE1 ITDKLRGEINKVVNKYIDQGIAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ITDKLRGEINKVVNKYIDQGIAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFA
              220       230       240       250       260       270

              340       350       360       370       380       390
pF1KE1 SNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGINISEEA
       :::::::::::::::::::::::::::::::::::::::::::.                
CCDS82 SNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQVP               
              280       290       300       310                    

              400       410       420       430       440       450
pF1KE1 LNHLGEIGTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQ

>>CCDS42588.1 RUVBL2 gene_id:10856|Hs108|chr19            (463 aa)
 initn: 1229 init1: 483 opt: 747  Z-score: 844.1  bits: 165.5 E(32554): 1.1e-40
Smith-Waterman score: 1267; 43.0% identity (73.9% similar) in 456 aa overlap (2-455:9-451)

                      10        20        30        40        50   
pF1KE1        MKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIV
               :. :....:. .::..:::..:::::..   .::..:.:::  ::.: ::..
CCDS42 MATVTATTKVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVL
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KE1 ELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLM
       :.:.  :.::::::.:: :::::::.:...:: ::  .::  ..:::..: :..:::.: 
CCDS42 EMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALT
               70        80        90       100       110       120

           120       130       140       150       160       170   
pF1KE1 ENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLD
       . :::.::.::::  :. ::::.:.   . . :  : :. ...  . :::..      : 
CCDS42 QAFRRSIGVRIKEETEIIEGEVVEI---QIDRPATGTGSKVGK--LTLKTTEMETIYDLG
              130       140          150       160         170     

           180       190       200       210         220       230 
pF1KE1 PSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEE--YVPLPKGDVHKK
        ...::: :..:.::::: :.  .: ... ::  : : ..:  . .  .:  : :...:.
CCDS42 TKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKR
         180       190       200       210       220       230     

             240       250       260       270       280       290 
pF1KE1 KEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGI
       ::... :.::..:: :.: ::   .:.    :..    :: ...: .::  : .. ..: 
CCDS42 KEVVHTVSLHEIDVINSRTQG---FLA----LFSGDTGEIKSEVREQINAKVAEWREEGK
         240       250              260       270       280        

             300       310       320       330       340       350 
pF1KE1 AELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIP
       ::..:::::.::::::::: :..:.:::::..::..:.:.:::   :::: .  ::::::
CCDS42 AEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGT-SYQSPHGIP
      290       300       310       320       330        340       

             360       370       380       390       400       410 
pF1KE1 LDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLT
       .:::::..:. :  :. .. :::..:: . : ...::.: . : .:: .:.:::..::.:
CCDS42 IDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLIT
       350       360       370       380       390       400       

             420       430       440       450                 
pF1KE1 PANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK           
        :.:. .      .. . ....  :: : . :.. . . :: ..            
CCDS42 AASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFNELKGETMDTS
       410       420       430       440       450       460   




456 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 01:38:38 2016 done: Mon Nov  7 01:38:39 2016
 Total Scan time:  2.670 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]