Result of FASTA (ccds) for
pFN21AB3085
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3085, 211 aa
1>>>pF1KB3085 211 - 211 aa - 211 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8355+/-0.000731; mu= 17.5946+/- 0.044
mean_var=73.4865+/-14.410, 0's: 0 Z-trim(110.4): 45 B-trim: 0 in 0/51
Lambda= 0.149613
statistics sampled from 11538 (11583) to 11538 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.356), width: 16
Scan time: 2.160
The best scores are: opt bits E(32554)
CCDS3295.1 CLDN1 gene_id:9076|Hs108|chr3 ( 211) 1419 314.7 2.7e-86
CCDS11096.1 CLDN7 gene_id:1366|Hs108|chr17 ( 211) 925 208.0 3.4e-54
CCDS44125.1 CLDN19 gene_id:149461|Hs108|chr1 ( 211) 887 199.8 1e-51
CCDS471.1 CLDN19 gene_id:149461|Hs108|chr1 ( 224) 881 198.6 2.6e-51
CCDS5559.1 CLDN3 gene_id:1365|Hs108|chr7 ( 220) 734 166.8 9.1e-42
CCDS5560.1 CLDN4 gene_id:1364|Hs108|chr7 ( 209) 729 165.7 1.9e-41
CCDS10487.1 CLDN9 gene_id:9080|Hs108|chr16 ( 217) 727 165.3 2.6e-41
CCDS10488.1 CLDN6 gene_id:9074|Hs108|chr16 ( 220) 685 156.3 1.4e-38
CCDS13763.2 CLDN5 gene_id:7122|Hs108|chr22 ( 303) 684 156.2 2e-38
CCDS13645.1 CLDN14 gene_id:23562|Hs108|chr21 ( 239) 649 148.5 3.2e-36
CCDS54081.1 CLDN7 gene_id:1366|Hs108|chr17 ( 145) 619 141.8 2e-34
CCDS53306.1 CLDN19 gene_id:149461|Hs108|chr1 ( 218) 608 139.6 1.4e-33
CCDS13586.1 CLDN17 gene_id:26285|Hs108|chr21 ( 224) 602 138.3 3.5e-33
CCDS13587.1 CLDN8 gene_id:9073|Hs108|chr21 ( 225) 588 135.3 2.8e-32
CCDS14524.1 CLDN2 gene_id:9075|Hs108|chrX ( 230) 529 122.6 2e-28
CCDS5249.1 CLDN20 gene_id:49861|Hs108|chr6 ( 219) 493 114.8 4.1e-26
CCDS9476.1 CLDN10 gene_id:9071|Hs108|chr13 ( 228) 490 114.2 6.7e-26
CCDS5717.1 CLDN15 gene_id:24146|Hs108|chr7 ( 228) 479 111.8 3.5e-25
CCDS9475.1 CLDN10 gene_id:9071|Hs108|chr13 ( 226) 449 105.3 3.1e-23
CCDS54824.1 CLDN24 gene_id:100132463|Hs108|chr4 ( 220) 446 104.7 4.7e-23
CCDS43286.1 CLDN22 gene_id:53842|Hs108|chr4 ( 220) 424 99.9 1.3e-21
CCDS44736.1 CLDN25 gene_id:644672|Hs108|chr11 ( 229) 382 90.9 7e-19
CCDS3213.1 CLDN11 gene_id:5010|Hs108|chr3 ( 207) 379 90.2 1e-18
CCDS33862.1 CLDN18 gene_id:51208|Hs108|chr3 ( 261) 355 85.1 4.3e-17
CCDS3095.1 CLDN18 gene_id:51208|Hs108|chr3 ( 261) 355 85.1 4.3e-17
CCDS3296.1 CLDN16 gene_id:10686|Hs108|chr3 ( 305) 280 69.0 3.6e-12
>>CCDS3295.1 CLDN1 gene_id:9076|Hs108|chr3 (211 aa)
initn: 1419 init1: 1419 opt: 1419 Z-score: 1662.7 bits: 314.7 E(32554): 2.7e-86
Smith-Waterman score: 1419; 100.0% identity (100.0% similar) in 211 aa overlap (1-211:1-211)
10 20 30 40 50 60
pF1KB3 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA
130 140 150 160 170 180
190 200 210
pF1KB3 LLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV
:::::::::::::::::::::::::::::::
CCDS32 LLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV
190 200 210
>>CCDS11096.1 CLDN7 gene_id:1366|Hs108|chr17 (211 aa)
initn: 910 init1: 910 opt: 925 Z-score: 1086.4 bits: 208.0 E(32554): 3.4e-54
Smith-Waterman score: 925; 60.6% identity (86.4% similar) in 213 aa overlap (1-211:1-211)
10 20 30 40 50 60
pF1KB3 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG
:::.::::::: .:.:::.: .. ::.:::.. :::::::.::::::.::::.::.::::
CCDS11 MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV
...::..::.: ::..::::::::::...:: .:.::::.:::: .: ::.:.: :.:.
CCDS11 MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA
:: ::..:::: ::: .:::..:: .::.:. :.: .:::: :.: :::...: .::::
CCDS11 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA
130 140 150 160 170 180
190 200 210
pF1KB3 LLCCSCP--RKTTSYPTPRPYPKPAPSSGKDYV
:: :::: .. ..: .:: ::: .:.:.::
CCDS11 LLSCSCPGNESKAGYRVPRSYPKS--NSSKEYV
190 200 210
>>CCDS44125.1 CLDN19 gene_id:149461|Hs108|chr1 (211 aa)
initn: 876 init1: 876 opt: 887 Z-score: 1042.1 bits: 199.8 E(32554): 1e-51
Smith-Waterman score: 887; 57.1% identity (85.4% similar) in 212 aa overlap (1-211:1-211)
10 20 30 40 50 60
pF1KB3 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG
:::.::::::..::. ::.: :.:::::::. ::::: :.:: ..::::::::.:::::
CCDS44 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV
:.:::..:::: :.. .:..::::::..::: .:. ...::::: . ... . : :.:.
CCDS44 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA
:::.:.:::: :.:..::.. ..:::..: :::::::::: :::.:::.:.: .:::.
CCDS44 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS
130 140 150 160 170 180
190 200 210
pF1KB3 LLCCSCPRKTTSYPTPRPYPKPAPSSG-KDYV
.:::.::. .:.:: .:.::.. ..::
CCDS44 FLCCTCPEPERPNSSPQPY-RPGPSAAAREYV
190 200 210
>>CCDS471.1 CLDN19 gene_id:149461|Hs108|chr1 (224 aa)
initn: 864 init1: 864 opt: 881 Z-score: 1034.7 bits: 198.6 E(32554): 2.6e-51
Smith-Waterman score: 881; 57.8% identity (85.4% similar) in 206 aa overlap (1-206:1-205)
10 20 30 40 50 60
pF1KB3 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG
:::.::::::..::. ::.: :.:::::::. ::::: :.:: ..::::::::.:::::
CCDS47 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV
:.:::..:::: :.. .:..::::::..::: .:. ...::::: . ... . : :.:.
CCDS47 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA
:::.:.:::: :.:..::.. ..:::..: :::::::::: :::.:::.:.: .:::.
CCDS47 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS
130 140 150 160 170 180
190 200 210
pF1KB3 LLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV
.:::.::. .:.:: .:.::.
CCDS47 FLCCTCPEPERPNSSPQPY-RPGPSAAAREPVVKLPASAKGPLGV
190 200 210 220
>>CCDS5559.1 CLDN3 gene_id:1365|Hs108|chr7 (220 aa)
initn: 745 init1: 467 opt: 734 Z-score: 863.3 bits: 166.8 E(32554): 9.1e-42
Smith-Waterman score: 735; 50.2% identity (77.2% similar) in 219 aa overlap (5-211:4-220)
10 20 30 40 50 60
pF1KB3 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG
::.. : :: :::.:.:: :::.::. .. :.::.:.: ..:::::.:: ::::
CCDS55 MSMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTG
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV
:.::::.:::: : . :::.:::.::.:::......:: :: .: .:..:: . : ....
CCDS55 QMQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTA-KAKITI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA
..:..::::.: :: ..: .: :...::.:..: . :.: .:..:::::.: :::::
CCDS55 VAGVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGA
120 130 140 150 160 170
190 200 210
pF1KB3 LLCCSCP---RKTTS----YPTPRPYPKPAPSSG-----KDYV
::::::: .: :. : .:: :. : : ::::
CCDS55 LLCCSCPPREKKYTATKVVYSAPRS-TGPGASLGTGYDRKDYV
180 190 200 210 220
>>CCDS5560.1 CLDN4 gene_id:1364|Hs108|chr7 (209 aa)
initn: 822 init1: 488 opt: 729 Z-score: 857.8 bits: 165.7 E(32554): 1.9e-41
Smith-Waterman score: 729; 46.0% identity (80.6% similar) in 211 aa overlap (1-211:1-209)
10 20 30 40 50 60
pF1KB3 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG
::. :::..:. :: :::..... :::.::. .. :.::::.:...:::::.:: ::::
CCDS55 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV
:.::::.:::: : . :::.:::....:...........:: :: .:::: : : . .
CCDS55 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLED-ESAKAKTMI
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA
..:..:::::: ..: ..: .. :.:.::.:.. . . :.: .:..::::..: ::::.
CCDS55 VAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGG
120 130 140 150 160 170
190 200 210
pF1KB3 LLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV
::::.:: .: . : : .....::
CCDS55 LLCCNCPPRTDK-PYSAKYSAARSAAASNYV
180 190 200
>>CCDS10487.1 CLDN9 gene_id:9080|Hs108|chr16 (217 aa)
initn: 475 init1: 475 opt: 727 Z-score: 855.3 bits: 165.3 E(32554): 2.6e-41
Smith-Waterman score: 727; 49.1% identity (77.1% similar) in 218 aa overlap (1-211:1-217)
10 20 30 40 50 60
pF1KB3 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG
::..::.:::. :: :::.:..:: ::: :.. .. :..::.::...:::::::: ::::
CCDS10 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV
:.::::.:::: : . :::.::: :...::......:: .: .: :.:: : : :...
CCDS10 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVED-EGAKARIVL
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA
.:.:.::::. .:. . : .. :.:.::.:.. . :.: .:. :::::.: .:::.
CCDS10 TAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGG
120 130 140 150 160 170
190 200 210
pF1KB3 LLCCSCPRKTTSYPT-PR-PYPKPAPS--SG---KDYV
::::.:: . : :: : :. : :: .:::
CCDS10 LLCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV
180 190 200 210
>>CCDS10488.1 CLDN6 gene_id:9074|Hs108|chr16 (220 aa)
initn: 462 init1: 441 opt: 685 Z-score: 806.2 bits: 156.3 E(32554): 1.4e-38
Smith-Waterman score: 685; 44.0% identity (78.3% similar) in 207 aa overlap (1-205:1-206)
10 20 30 40 50 60
pF1KB3 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG
::.::.:.:: .:..:::....:: :::.:.. .. :..::.::...:::::::: ::::
CCDS10 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV
:.::::.:::: : . :::.::: :...:.......: .: :: :.:. . .: :...
CCDS10 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKD-SKARLVL
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA
.: .:...:. :. . : .. :...::.:.. . :.: .:. ::::..: ::::.
CCDS10 TSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGG
120 130 140 150 160 170
190 200 210
pF1KB3 LLCCSCPRKTTSYPTPRP--YPKPAPSSGKDYV
::::.:: .. :. : ::.
CCDS10 LLCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV
180 190 200 210 220
>>CCDS13763.2 CLDN5 gene_id:7122|Hs108|chr22 (303 aa)
initn: 662 init1: 397 opt: 684 Z-score: 803.2 bits: 156.2 E(32554): 2e-38
Smith-Waterman score: 684; 45.3% identity (74.3% similar) in 214 aa overlap (1-210:86-297)
10 20 30
pF1KB3 MANAGLQLLGFILAFLGWIGAIVSTALPQW
:..:.:..::..: ..:: : :.. .::.:
CCDS13 GAKAPGPAQGAAQHGLGGSAGLRVRVSPLAMGSAALEILGLVLCLVGWGGLILACGLPMW
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB3 RIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCKVFDSLLNLSSTLQATRALMVVGILL
.. .. ::::::. ..::::::: ::::..::::.::.: ::. .::.::: : ..::
CCDS13 QVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLL
120 130 140 150 160 170
100 110 120 130 140 150
pF1KB3 GVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAIFLLAGLAILVATAWYGNRIVQEFYD
. .:.::. .: .: :. . : :.:. ::...:. :: :: :..: .:.::::
CCDS13 AFVALFVTLAGAQCTTCVAPGPA-KARVALTGGVLYLFCGLLALVPLCWFANIVVREFYD
180 190 200 210 220 230
160 170 180 190 200
pF1KB3 PMTPVNARYEFGQALFTGWAAASLCLLGGALLCCS---CP-RKTTSYPTPRPYPKPAPSS
: .::. .::.: ::. ::::..: ..:: ::::. : : :.:. :. :..
CCDS13 PSVPVSQKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPR-RPTA
240 250 260 270 280 290
210
pF1KB3 GKDYV
::
CCDS13 TGDYDKKNYV
300
>>CCDS13645.1 CLDN14 gene_id:23562|Hs108|chr21 (239 aa)
initn: 660 init1: 386 opt: 649 Z-score: 763.7 bits: 148.5 E(32554): 3.2e-36
Smith-Waterman score: 653; 44.8% identity (72.4% similar) in 221 aa overlap (1-209:1-219)
10 20 30 40 50 60
pF1KB3 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG
::....:::::.:.::: .:....: ::.:: ...: ::.:: .. .:::: :: .:::
CCDS13 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV
::... ::: : . :::.:::::.. ::. :: :..:::: .: . . : .:.
CCDS13 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPA-KTTFAI
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA
.::..:.:::: .::..: : .::.::.:. : . ..:.::::. :. ..:: :.::.
CCDS13 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT
120 130 140 150 160 170
190 200 210
pF1KB3 LLCCSC------------PRKTTSYPTPRPYPKPAPSSGKDYV
::: :: :: ::. . : .: :.. ::
CCDS13 LLCLSCQDEAPYRPYQAPPRATTTTANTAPAYQP-PAAYKDNRAPSVTSATHSGYRLNDY
180 190 200 210 220 230
CCDS13 V
211 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:50:02 2016 done: Sat Nov 5 04:50:02 2016
Total Scan time: 2.160 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]