Result of FASTA (omim) for
pFN21AB8711
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8711, 482 aa
1>>>pF1KB8711 482 - 482 aa - 482 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8662+/-0.000396; mu= 11.1185+/- 0.025
mean_var=110.0626+/-21.551, 0's: 0 Z-trim(114.9): 57 B-trim: 34 in 3/50
Lambda= 0.122252
statistics sampled from 24893 (24950) to 24893 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.293), width: 16
Scan time: 8.530
The best scores are: opt bits E(85289)
NP_001263407 (OMIM: 147625) islet cell autoantigen ( 482) 3204 576.1 7.6e-164
XP_016867610 (OMIM: 147625) PREDICTED: islet cell ( 482) 3204 576.1 7.6e-164
XP_016867609 (OMIM: 147625) PREDICTED: islet cell ( 482) 3204 576.1 7.6e-164
XP_016867608 (OMIM: 147625) PREDICTED: islet cell ( 482) 3204 576.1 7.6e-164
XP_005249792 (OMIM: 147625) PREDICTED: islet cell ( 482) 3204 576.1 7.6e-164
NP_004959 (OMIM: 147625) islet cell autoantigen 1 ( 483) 3192 574.0 3.3e-163
XP_016867606 (OMIM: 147625) PREDICTED: islet cell ( 483) 3192 574.0 3.3e-163
NP_001129492 (OMIM: 147625) islet cell autoantigen ( 483) 3192 574.0 3.3e-163
XP_016867607 (OMIM: 147625) PREDICTED: islet cell ( 483) 3192 574.0 3.3e-163
NP_071682 (OMIM: 147625) islet cell autoantigen 1 ( 483) 3192 574.0 3.3e-163
XP_016867614 (OMIM: 147625) PREDICTED: islet cell ( 409) 2623 473.6 4.6e-133
XP_016867611 (OMIM: 147625) PREDICTED: islet cell ( 409) 2623 473.6 4.6e-133
XP_016867613 (OMIM: 147625) PREDICTED: islet cell ( 409) 2623 473.6 4.6e-133
XP_016867612 (OMIM: 147625) PREDICTED: islet cell ( 409) 2623 473.6 4.6e-133
XP_011513653 (OMIM: 147625) PREDICTED: islet cell ( 511) 2015 366.4 1.1e-100
XP_011513654 (OMIM: 147625) PREDICTED: islet cell ( 511) 2015 366.4 1.1e-100
XP_016867605 (OMIM: 147625) PREDICTED: islet cell ( 511) 2015 366.4 1.1e-100
XP_011513655 (OMIM: 147625) PREDICTED: islet cell ( 511) 2015 366.4 1.1e-100
XP_011513652 (OMIM: 147625) PREDICTED: islet cell ( 511) 2015 366.4 1.1e-100
XP_011513649 (OMIM: 147625) PREDICTED: islet cell ( 512) 2003 364.3 4.6e-100
XP_011513650 (OMIM: 147625) PREDICTED: islet cell ( 512) 2003 364.3 4.6e-100
XP_011513651 (OMIM: 147625) PREDICTED: islet cell ( 512) 2003 364.3 4.6e-100
XP_011513647 (OMIM: 147625) PREDICTED: islet cell ( 512) 2003 364.3 4.6e-100
XP_011513648 (OMIM: 147625) PREDICTED: islet cell ( 512) 2003 364.3 4.6e-100
XP_011513656 (OMIM: 147625) PREDICTED: islet cell ( 438) 1434 263.9 6.6e-70
XP_011513659 (OMIM: 147625) PREDICTED: islet cell ( 286) 1201 222.7 1.1e-57
XP_011513657 (OMIM: 147625) PREDICTED: islet cell ( 303) 1201 222.7 1.1e-57
XP_011513658 (OMIM: 147625) PREDICTED: islet cell ( 303) 1201 222.7 1.1e-57
>>NP_001263407 (OMIM: 147625) islet cell autoantigen 1 i (482 aa)
initn: 3204 init1: 3204 opt: 3204 Z-score: 3062.6 bits: 576.1 E(85289): 7.6e-164
Smith-Waterman score: 3204; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:1-482)
10 20 30 40 50 60
pF1KB8 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
430 440 450 460 470 480
pF1KB8 NA
::
NP_001 NA
>>XP_016867610 (OMIM: 147625) PREDICTED: islet cell auto (482 aa)
initn: 3204 init1: 3204 opt: 3204 Z-score: 3062.6 bits: 576.1 E(85289): 7.6e-164
Smith-Waterman score: 3204; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:1-482)
10 20 30 40 50 60
pF1KB8 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
430 440 450 460 470 480
pF1KB8 NA
::
XP_016 NA
>>XP_016867609 (OMIM: 147625) PREDICTED: islet cell auto (482 aa)
initn: 3204 init1: 3204 opt: 3204 Z-score: 3062.6 bits: 576.1 E(85289): 7.6e-164
Smith-Waterman score: 3204; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:1-482)
10 20 30 40 50 60
pF1KB8 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
430 440 450 460 470 480
pF1KB8 NA
::
XP_016 NA
>>XP_016867608 (OMIM: 147625) PREDICTED: islet cell auto (482 aa)
initn: 3204 init1: 3204 opt: 3204 Z-score: 3062.6 bits: 576.1 E(85289): 7.6e-164
Smith-Waterman score: 3204; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:1-482)
10 20 30 40 50 60
pF1KB8 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
430 440 450 460 470 480
pF1KB8 NA
::
XP_016 NA
>>XP_005249792 (OMIM: 147625) PREDICTED: islet cell auto (482 aa)
initn: 3204 init1: 3204 opt: 3204 Z-score: 3062.6 bits: 576.1 E(85289): 7.6e-164
Smith-Waterman score: 3204; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:1-482)
10 20 30 40 50 60
pF1KB8 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
430 440 450 460 470 480
pF1KB8 NA
::
XP_005 NA
>>NP_004959 (OMIM: 147625) islet cell autoantigen 1 isof (483 aa)
initn: 3190 init1: 3155 opt: 3192 Z-score: 3051.1 bits: 574.0 E(85289): 3.3e-163
Smith-Waterman score: 3192; 99.8% identity (99.8% similar) in 483 aa overlap (1-482:1-483)
10 20 30 40 50
pF1KB8 MSGHKC-YPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
430 440 450 460 470 480
480
pF1KB8 LNA
:::
NP_004 LNA
>>XP_016867606 (OMIM: 147625) PREDICTED: islet cell auto (483 aa)
initn: 3190 init1: 3155 opt: 3192 Z-score: 3051.1 bits: 574.0 E(85289): 3.3e-163
Smith-Waterman score: 3192; 99.8% identity (99.8% similar) in 483 aa overlap (1-482:1-483)
10 20 30 40 50
pF1KB8 MSGHKC-YPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
430 440 450 460 470 480
480
pF1KB8 LNA
:::
XP_016 LNA
>>NP_001129492 (OMIM: 147625) islet cell autoantigen 1 i (483 aa)
initn: 3190 init1: 3155 opt: 3192 Z-score: 3051.1 bits: 574.0 E(85289): 3.3e-163
Smith-Waterman score: 3192; 99.8% identity (99.8% similar) in 483 aa overlap (1-482:1-483)
10 20 30 40 50
pF1KB8 MSGHKC-YPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
430 440 450 460 470 480
480
pF1KB8 LNA
:::
NP_001 LNA
>>XP_016867607 (OMIM: 147625) PREDICTED: islet cell auto (483 aa)
initn: 3190 init1: 3155 opt: 3192 Z-score: 3051.1 bits: 574.0 E(85289): 3.3e-163
Smith-Waterman score: 3192; 99.8% identity (99.8% similar) in 483 aa overlap (1-482:1-483)
10 20 30 40 50
pF1KB8 MSGHKC-YPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
430 440 450 460 470 480
480
pF1KB8 LNA
:::
XP_016 LNA
>>NP_071682 (OMIM: 147625) islet cell autoantigen 1 isof (483 aa)
initn: 3190 init1: 3155 opt: 3192 Z-score: 3051.1 bits: 574.0 E(85289): 3.3e-163
Smith-Waterman score: 3192; 99.8% identity (99.8% similar) in 483 aa overlap (1-482:1-483)
10 20 30 40 50
pF1KB8 MSGHKC-YPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
430 440 450 460 470 480
480
pF1KB8 LNA
:::
NP_071 LNA
482 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 21:34:30 2016 done: Sat Nov 5 21:34:31 2016
Total Scan time: 8.530 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]