Result of FASTA (omim) for
pFN21AB5769
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5769, 750 aa
1>>>pF1KB5769 750 - 750 aa - 750 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.7150+/-0.000348; mu= -0.5515+/- 0.022
mean_var=218.5081+/-45.009, 0's: 0 Z-trim(122.1): 366 B-trim: 350 in 1/52
Lambda= 0.086764
statistics sampled from 39336 (39727) to 39336 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.466), width: 16
Scan time: 12.190
The best scores are: opt bits E(85289)
NP_001306779 (OMIM: 610576) rho GTPase-activating ( 821) 5135 655.8 2e-187
NP_001306781 (OMIM: 610576) rho GTPase-activating ( 566) 3875 498.0 4.3e-140
XP_016875289 (OMIM: 610576) PREDICTED: rho GTPase- ( 566) 3875 498.0 4.3e-140
XP_005269140 (OMIM: 610576) PREDICTED: rho GTPase- ( 566) 3875 498.0 4.3e-140
NP_001073626 (OMIM: 610576) rho GTPase-activating ( 640) 3056 395.6 3.5e-109
XP_011536961 (OMIM: 610576) PREDICTED: rho GTPase- ( 640) 3056 395.6 3.5e-109
XP_011536958 (OMIM: 610576) PREDICTED: rho GTPase- ( 731) 3056 395.6 3.9e-109
NP_115885 (OMIM: 610576) rho GTPase-activating pro ( 731) 3056 395.6 3.9e-109
XP_005269141 (OMIM: 610576) PREDICTED: rho GTPase- ( 535) 2921 378.6 3.6e-104
XP_005269142 (OMIM: 610576) PREDICTED: rho GTPase- ( 535) 2921 378.6 3.6e-104
XP_011536959 (OMIM: 610576) PREDICTED: rho GTPase- ( 719) 2921 378.7 4.7e-104
NP_001306780 (OMIM: 610576) rho GTPase-activating ( 420) 2825 366.5 1.2e-100
XP_011536960 (OMIM: 610576) PREDICTED: rho GTPase- ( 700) 2043 268.8 5.5e-71
XP_016875291 (OMIM: 610576) PREDICTED: rho GTPase- ( 516) 1954 257.6 9.7e-68
XP_016875290 (OMIM: 610576) PREDICTED: rho GTPase- ( 547) 1954 257.6 1e-67
NP_001073625 (OMIM: 610576) rho GTPase-activating ( 547) 1954 257.6 1e-67
XP_016875292 (OMIM: 610576) PREDICTED: rho GTPase- ( 456) 1796 237.8 7.8e-62
XP_016875293 (OMIM: 610576) PREDICTED: rho GTPase- ( 425) 1332 179.7 2.2e-44
XP_011522773 (OMIM: 610591) PREDICTED: rho GTPase- ( 865) 740 105.7 8.3e-22
XP_011522776 (OMIM: 610591) PREDICTED: rho GTPase- ( 581) 732 104.6 1.2e-21
XP_011522774 (OMIM: 610591) PREDICTED: rho GTPase- ( 722) 732 104.7 1.4e-21
XP_016879800 (OMIM: 610591) PREDICTED: rho GTPase- ( 922) 732 104.7 1.8e-21
XP_011522770 (OMIM: 610591) PREDICTED: rho GTPase- ( 922) 732 104.7 1.8e-21
XP_011522771 (OMIM: 610591) PREDICTED: rho GTPase- ( 900) 722 103.5 4.1e-21
NP_954976 (OMIM: 610591) rho GTPase-activating pro ( 548) 463 70.9 1.5e-11
XP_005257185 (OMIM: 610591) PREDICTED: rho GTPase- ( 667) 463 71.0 1.8e-11
XP_016879801 (OMIM: 610591) PREDICTED: rho GTPase- ( 689) 463 71.0 1.9e-11
XP_006721810 (OMIM: 610591) PREDICTED: rho GTPase- ( 867) 463 71.0 2.3e-11
NP_001269219 (OMIM: 610591) rho GTPase-activating ( 889) 463 71.0 2.3e-11
XP_006721808 (OMIM: 610591) PREDICTED: rho GTPase- ( 889) 463 71.0 2.3e-11
XP_011509785 (OMIM: 610578) PREDICTED: rho GTPase- ( 397) 445 68.6 5.6e-11
XP_016859989 (OMIM: 610578) PREDICTED: rho GTPase- ( 432) 445 68.6 6e-11
XP_011509781 (OMIM: 610578) PREDICTED: rho GTPase- ( 475) 445 68.7 6.5e-11
NP_060930 (OMIM: 610578) rho GTPase-activating pro ( 475) 445 68.7 6.5e-11
XP_016859988 (OMIM: 610578) PREDICTED: rho GTPase- ( 475) 445 68.7 6.5e-11
XP_011509784 (OMIM: 610578) PREDICTED: rho GTPase- ( 416) 427 66.4 2.8e-10
XP_011509783 (OMIM: 610578) PREDICTED: rho GTPase- ( 435) 427 66.4 2.9e-10
XP_011509786 (OMIM: 610578) PREDICTED: rho GTPase- ( 342) 418 65.2 5.2e-10
XP_016880032 (OMIM: 600365) PREDICTED: active brea ( 660) 407 64.0 2.3e-09
XP_016880031 (OMIM: 600365) PREDICTED: active brea ( 663) 407 64.0 2.3e-09
XP_011522117 (OMIM: 600365) PREDICTED: active brea ( 832) 407 64.0 2.8e-09
XP_011522116 (OMIM: 600365) PREDICTED: active brea ( 832) 407 64.0 2.8e-09
XP_011522115 (OMIM: 600365) PREDICTED: active brea ( 841) 407 64.0 2.9e-09
XP_011522114 (OMIM: 600365) PREDICTED: active brea ( 865) 407 64.0 2.9e-09
XP_011522112 (OMIM: 600365) PREDICTED: active brea ( 878) 407 64.0 3e-09
XP_011522772 (OMIM: 610591) PREDICTED: rho GTPase- ( 870) 406 63.9 3.2e-09
XP_016880029 (OMIM: 600365) PREDICTED: active brea (1104) 407 64.1 3.6e-09
XP_016880028 (OMIM: 600365) PREDICTED: active brea (1137) 407 64.1 3.7e-09
XP_016872443 (OMIM: 610577) PREDICTED: rho GTPase- ( 742) 390 61.9 1.1e-08
NP_001257627 (OMIM: 610577) rho GTPase-activating ( 769) 390 61.9 1.2e-08
>>NP_001306779 (OMIM: 610576) rho GTPase-activating prot (821 aa)
initn: 5135 init1: 5135 opt: 5135 Z-score: 3486.0 bits: 655.8 E(85289): 2e-187
Smith-Waterman score: 5135; 99.9% identity (100.0% similar) in 750 aa overlap (1-750:72-821)
10 20 30
pF1KB5 MLSSRWWPSSWGILGLGPRSPPRGSQLCAL
::::::::::::::::::::::::::::::
NP_001 EEWPDSHHYPGPTPAPESSDGPHKVTVLATMLSSRWWPSSWGILGLGPRSPPRGSQLCAL
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB5 YAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYMIEESIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYMIEESIPS
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB5 QSPTTVIPGQLLWTPGPKLFHGSLEELSQALPSRAQASSEQPPPLPRKMCRSVSTDNLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSPTTVIPGQLLWTPGPKLFHGSLEELSQALPSRAQASSEQPPPLPRKMCRSVSTDNLSP
170 180 190 200 210 220
160 170 180 190 200 210
pF1KB5 SFLKPFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPAC
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLLKPFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPAC
230 240 250 260 270 280
220 230 240 250 260 270
pF1KB5 PLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVL
290 300 310 320 330 340
280 290 300 310 320 330
pF1KB5 QPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLN
350 360 370 380 390 400
340 350 360 370 380 390
pF1KB5 MTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAAL
410 420 430 440 450 460
400 410 420 430 440 450
pF1KB5 AHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTG
470 480 490 500 510 520
460 470 480 490 500 510
pF1KB5 RDQGSGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDQGSGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQN
530 540 550 560 570 580
520 530 540 550 560 570
pF1KB5 RVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRG
590 600 610 620 630 640
580 590 600 610 620 630
pF1KB5 LDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVV
650 660 670 680 690 700
640 650 660 670 680 690
pF1KB5 TGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLE
710 720 730 740 750 760
700 710 720 730 740 750
pF1KB5 HLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
770 780 790 800 810 820
>>NP_001306781 (OMIM: 610576) rho GTPase-activating prot (566 aa)
initn: 3875 init1: 3875 opt: 3875 Z-score: 2636.1 bits: 498.0 E(85289): 4.3e-140
Smith-Waterman score: 3875; 100.0% identity (100.0% similar) in 566 aa overlap (185-750:1-566)
160 170 180 190 200 210
pF1KB5 PFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
::::::::::::::::::::::::::::::
NP_001 MSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
10 20 30
220 230 240 250 260 270
pF1KB5 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB5 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
100 110 120 130 140 150
340 350 360 370 380 390
pF1KB5 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
160 170 180 190 200 210
400 410 420 430 440 450
pF1KB5 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
220 230 240 250 260 270
460 470 480 490 500 510
pF1KB5 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
280 290 300 310 320 330
520 530 540 550 560 570
pF1KB5 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
340 350 360 370 380 390
580 590 600 610 620 630
pF1KB5 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
400 410 420 430 440 450
640 650 660 670 680 690
pF1KB5 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
460 470 480 490 500 510
700 710 720 730 740 750
pF1KB5 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
520 530 540 550 560
>>XP_016875289 (OMIM: 610576) PREDICTED: rho GTPase-acti (566 aa)
initn: 3875 init1: 3875 opt: 3875 Z-score: 2636.1 bits: 498.0 E(85289): 4.3e-140
Smith-Waterman score: 3875; 100.0% identity (100.0% similar) in 566 aa overlap (185-750:1-566)
160 170 180 190 200 210
pF1KB5 PFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
::::::::::::::::::::::::::::::
XP_016 MSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
10 20 30
220 230 240 250 260 270
pF1KB5 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB5 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
100 110 120 130 140 150
340 350 360 370 380 390
pF1KB5 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
160 170 180 190 200 210
400 410 420 430 440 450
pF1KB5 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
220 230 240 250 260 270
460 470 480 490 500 510
pF1KB5 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
280 290 300 310 320 330
520 530 540 550 560 570
pF1KB5 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
340 350 360 370 380 390
580 590 600 610 620 630
pF1KB5 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
400 410 420 430 440 450
640 650 660 670 680 690
pF1KB5 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
460 470 480 490 500 510
700 710 720 730 740 750
pF1KB5 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
520 530 540 550 560
>>XP_005269140 (OMIM: 610576) PREDICTED: rho GTPase-acti (566 aa)
initn: 3875 init1: 3875 opt: 3875 Z-score: 2636.1 bits: 498.0 E(85289): 4.3e-140
Smith-Waterman score: 3875; 100.0% identity (100.0% similar) in 566 aa overlap (185-750:1-566)
160 170 180 190 200 210
pF1KB5 PFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
::::::::::::::::::::::::::::::
XP_005 MSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
10 20 30
220 230 240 250 260 270
pF1KB5 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB5 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
100 110 120 130 140 150
340 350 360 370 380 390
pF1KB5 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
160 170 180 190 200 210
400 410 420 430 440 450
pF1KB5 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
220 230 240 250 260 270
460 470 480 490 500 510
pF1KB5 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
280 290 300 310 320 330
520 530 540 550 560 570
pF1KB5 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
340 350 360 370 380 390
580 590 600 610 620 630
pF1KB5 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
400 410 420 430 440 450
640 650 660 670 680 690
pF1KB5 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
460 470 480 490 500 510
700 710 720 730 740 750
pF1KB5 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
520 530 540 550 560
>>NP_001073626 (OMIM: 610576) rho GTPase-activating prot (640 aa)
initn: 3050 init1: 3050 opt: 3056 Z-score: 2081.2 bits: 395.6 E(85289): 3.5e-109
Smith-Waterman score: 4331; 97.0% identity (97.1% similar) in 658 aa overlap (1-658:1-639)
10 20 30 40 50 60
pF1KB5 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSFLKPFQEGPSGRSLSQEDLPSEASASTAG
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
NP_001 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 TELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGSGPAELSAGEDE
::::::::::::::::: ::::::::::::::::::::::::
NP_001 TELRAWHRALRTVIERL-------------------DRENPLELRLSGSGPAELSAGEDE
430 440 450 460
490 500 510 520 530 540
pF1KB5 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB5 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB5 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALG
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB5 SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP
>>XP_011536961 (OMIM: 610576) PREDICTED: rho GTPase-acti (640 aa)
initn: 3050 init1: 3050 opt: 3056 Z-score: 2081.2 bits: 395.6 E(85289): 3.5e-109
Smith-Waterman score: 4331; 97.0% identity (97.1% similar) in 658 aa overlap (1-658:1-639)
10 20 30 40 50 60
pF1KB5 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSFLKPFQEGPSGRSLSQEDLPSEASASTAG
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
XP_011 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 TELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGSGPAELSAGEDE
::::::::::::::::: ::::::::::::::::::::::::
XP_011 TELRAWHRALRTVIERL-------------------DRENPLELRLSGSGPAELSAGEDE
430 440 450 460
490 500 510 520 530 540
pF1KB5 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB5 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB5 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALG
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB5 SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP
>>XP_011536958 (OMIM: 610576) PREDICTED: rho GTPase-acti (731 aa)
initn: 3050 init1: 3050 opt: 3056 Z-score: 2080.4 bits: 395.6 E(85289): 3.9e-109
Smith-Waterman score: 4953; 97.3% identity (97.5% similar) in 750 aa overlap (1-750:1-731)
10 20 30 40 50 60
pF1KB5 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSFLKPFQEGPSGRSLSQEDLPSEASASTAG
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
XP_011 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 TELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGSGPAELSAGEDE
::::::::::::::::: ::::::::::::::::::::::::
XP_011 TELRAWHRALRTVIERL-------------------DRENPLELRLSGSGPAELSAGEDE
430 440 450 460
490 500 510 520 530 540
pF1KB5 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB5 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB5 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALAL
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB5 SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP
650 660 670 680 690 700
730 740 750
pF1KB5 EQETSDPAAHALYPGQLVQLMLTNFTSLFP
::::::::::::::::::::::::::::::
XP_011 EQETSDPAAHALYPGQLVQLMLTNFTSLFP
710 720 730
>>NP_115885 (OMIM: 610576) rho GTPase-activating protein (731 aa)
initn: 3050 init1: 3050 opt: 3056 Z-score: 2080.4 bits: 395.6 E(85289): 3.9e-109
Smith-Waterman score: 4953; 97.3% identity (97.5% similar) in 750 aa overlap (1-750:1-731)
10 20 30 40 50 60
pF1KB5 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSFLKPFQEGPSGRSLSQEDLPSEASASTAG
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
NP_115 LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 TELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGSGPAELSAGEDE
::::::::::::::::: ::::::::::::::::::::::::
NP_115 TELRAWHRALRTVIERL-------------------DRENPLELRLSGSGPAELSAGEDE
430 440 450 460
490 500 510 520 530 540
pF1KB5 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 EEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVF
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB5 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVT
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB5 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALAL
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB5 SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRP
650 660 670 680 690 700
730 740 750
pF1KB5 EQETSDPAAHALYPGQLVQLMLTNFTSLFP
::::::::::::::::::::::::::::::
NP_115 EQETSDPAAHALYPGQLVQLMLTNFTSLFP
710 720 730
>>XP_005269141 (OMIM: 610576) PREDICTED: rho GTPase-acti (535 aa)
initn: 2897 init1: 2897 opt: 2921 Z-score: 1991.1 bits: 378.6 E(85289): 3.6e-104
Smith-Waterman score: 3589; 94.5% identity (94.5% similar) in 566 aa overlap (185-750:1-535)
160 170 180 190 200 210
pF1KB5 PFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
::::::::::::::::::::::::::::::
XP_005 MSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
10 20 30
220 230 240 250 260 270
pF1KB5 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB5 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
:::::::::::::::: :::::::::::::
XP_005 KGFRSDTGTPEPLDPQ-------------------------------EVEKSGLLNMTKI
100 110
340 350 360 370 380 390
pF1KB5 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
120 130 140 150 160 170
400 410 420 430 440 450
pF1KB5 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
180 190 200 210 220 230
460 470 480 490 500 510
pF1KB5 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
240 250 260 270 280 290
520 530 540 550 560 570
pF1KB5 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
300 310 320 330 340 350
580 590 600 610 620 630
pF1KB5 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
360 370 380 390 400 410
640 650 660 670 680 690
pF1KB5 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
420 430 440 450 460 470
700 710 720 730 740 750
pF1KB5 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
480 490 500 510 520 530
>>XP_005269142 (OMIM: 610576) PREDICTED: rho GTPase-acti (535 aa)
initn: 2897 init1: 2897 opt: 2921 Z-score: 1991.1 bits: 378.6 E(85289): 3.6e-104
Smith-Waterman score: 3589; 94.5% identity (94.5% similar) in 566 aa overlap (185-750:1-535)
160 170 180 190 200 210
pF1KB5 PFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
::::::::::::::::::::::::::::::
XP_005 MSEPPVYCNLVDLRRCPRSPPPGPACPLLQ
10 20 30
220 230 240 250 260 270
pF1KB5 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQA
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB5 KGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKI
:::::::::::::::: :::::::::::::
XP_005 KGFRSDTGTPEPLDPQ-------------------------------EVEKSGLLNMTKI
100 110
340 350 360 370 380 390
pF1KB5 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGR
120 130 140 150 160 170
400 410 420 430 440 450
pF1KB5 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQG
180 190 200 210 220 230
460 470 480 490 500 510
pF1KB5 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRN
240 250 260 270 280 290
520 530 540 550 560 570
pF1KB5 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVD
300 310 320 330 340 350
580 590 600 610 620 630
pF1KB5 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGAL
360 370 380 390 400 410
640 650 660 670 680 690
pF1KB5 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCR
420 430 440 450 460 470
700 710 720 730 740 750
pF1KB5 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP
480 490 500 510 520 530
750 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:36:43 2016 done: Sat Nov 5 07:36:44 2016
Total Scan time: 12.190 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]