Result of FASTA (omim) for
pFN21AB5930
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5930, 538 aa
1>>>pF1KB5930 538 - 538 aa - 538 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2713+/-0.000309; mu= 15.5550+/- 0.019
mean_var=126.8461+/-25.945, 0's: 0 Z-trim(120.5): 84 B-trim: 979 in 2/59
Lambda= 0.113877
statistics sampled from 35677 (35782) to 35677 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.42), width: 16
Scan time: 10.780
The best scores are: opt bits E(85289)
NP_851564 (OMIM: 147050,605383,615207) interleukin ( 538) 3838 641.7 1.6e-183
NP_068570 (OMIM: 147050,605383,615207) interleukin ( 538) 3838 641.7 1.6e-183
XP_016878746 (OMIM: 147050,605383,615207) PREDICTE ( 538) 3838 641.7 1.6e-183
XP_011544159 (OMIM: 147050,605383,615207) PREDICTE ( 560) 3838 641.8 1.7e-183
NP_851565 (OMIM: 147050,605383,615207) interleukin ( 560) 3838 641.8 1.7e-183
XP_011544160 (OMIM: 147050,605383,615207) PREDICTE ( 414) 2636 444.2 3.8e-124
NP_001333152 (OMIM: 146710) interleukin-2 receptor ( 551) 324 64.4 1e-09
NP_001333151 (OMIM: 146710) interleukin-2 receptor ( 551) 324 64.4 1e-09
NP_000869 (OMIM: 146710) interleukin-2 receptor su ( 551) 324 64.4 1e-09
XP_016885533 (OMIM: 300007) PREDICTED: interleukin ( 567) 229 48.8 5.2e-05
XP_016884984 (OMIM: 300007) PREDICTED: interleukin ( 567) 229 48.8 5.2e-05
XP_016884991 (OMIM: 300007) PREDICTED: interleukin ( 386) 226 48.2 5.5e-05
XP_016885540 (OMIM: 300007) PREDICTED: interleukin ( 386) 226 48.2 5.5e-05
XP_011543951 (OMIM: 300007) PREDICTED: interleukin ( 500) 226 48.3 6.6e-05
XP_016885536 (OMIM: 300007) PREDICTED: interleukin ( 500) 226 48.3 6.6e-05
XP_016884988 (OMIM: 300007) PREDICTED: interleukin ( 500) 226 48.3 6.6e-05
XP_016884987 (OMIM: 300007) PREDICTED: interleukin ( 500) 226 48.3 6.6e-05
XP_016885537 (OMIM: 300007) PREDICTED: interleukin ( 500) 226 48.3 6.6e-05
XP_016885535 (OMIM: 300007) PREDICTED: interleukin ( 500) 226 48.3 6.6e-05
XP_011529456 (OMIM: 300007) PREDICTED: interleukin ( 500) 226 48.3 6.6e-05
XP_016884986 (OMIM: 300007) PREDICTED: interleukin ( 500) 226 48.3 6.6e-05
NP_002177 (OMIM: 300007) interleukin-9 receptor is ( 521) 226 48.3 6.8e-05
XP_011543948 (OMIM: 300007) PREDICTED: interleukin ( 560) 226 48.3 7.2e-05
XP_011529454 (OMIM: 300007) PREDICTED: interleukin ( 560) 226 48.3 7.2e-05
XP_011529453 (OMIM: 300007) PREDICTED: interleukin ( 568) 226 48.3 7.3e-05
XP_011543947 (OMIM: 300007) PREDICTED: interleukin ( 568) 226 48.3 7.3e-05
NP_000112 (OMIM: 133100,133171) erythropoietin rec ( 508) 223 47.8 9.5e-05
XP_016878700 (OMIM: 147050,147781,609423) PREDICTE ( 304) 214 46.1 0.00018
NP_000386 (OMIM: 138981,614370) cytokine receptor ( 897) 201 44.4 0.0017
XP_005261397 (OMIM: 138981,614370) PREDICTED: cyto ( 903) 201 44.4 0.0017
NP_002176 (OMIM: 146661,608971) interleukin-7 rece ( 459) 184 41.4 0.0075
NP_001244336 (OMIM: 147050,147781,609423) interleu ( 810) 187 42.1 0.008
XP_011544129 (OMIM: 147050,147781,609423) PREDICTE ( 825) 187 42.1 0.0081
XP_011544128 (OMIM: 147050,147781,609423) PREDICTE ( 825) 187 42.1 0.0081
NP_000409 (OMIM: 147050,147781,609423) interleukin ( 825) 187 42.1 0.0081
XP_011544127 (OMIM: 147050,147781,609423) PREDICTE ( 825) 187 42.1 0.0081
NP_001244335 (OMIM: 147050,147781,609423) interleu ( 825) 187 42.1 0.0081
>>NP_851564 (OMIM: 147050,605383,615207) interleukin-21 (538 aa)
initn: 3838 init1: 3838 opt: 3838 Z-score: 3415.7 bits: 641.7 E(85289): 1.6e-183
Smith-Waterman score: 3838; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538)
10 20 30 40 50 60
pF1KB5 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS
430 440 450 460 470 480
490 500 510 520 530
pF1KB5 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
490 500 510 520 530
>>NP_068570 (OMIM: 147050,605383,615207) interleukin-21 (538 aa)
initn: 3838 init1: 3838 opt: 3838 Z-score: 3415.7 bits: 641.7 E(85289): 1.6e-183
Smith-Waterman score: 3838; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538)
10 20 30 40 50 60
pF1KB5 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS
430 440 450 460 470 480
490 500 510 520 530
pF1KB5 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
490 500 510 520 530
>>XP_016878746 (OMIM: 147050,605383,615207) PREDICTED: i (538 aa)
initn: 3838 init1: 3838 opt: 3838 Z-score: 3415.7 bits: 641.7 E(85289): 1.6e-183
Smith-Waterman score: 3838; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538)
10 20 30 40 50 60
pF1KB5 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS
430 440 450 460 470 480
490 500 510 520 530
pF1KB5 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
490 500 510 520 530
>>XP_011544159 (OMIM: 147050,605383,615207) PREDICTED: i (560 aa)
initn: 3838 init1: 3838 opt: 3838 Z-score: 3415.5 bits: 641.8 E(85289): 1.7e-183
Smith-Waterman score: 3838; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:23-560)
10 20 30
pF1KB5 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILE
::::::::::::::::::::::::::::::::::::::
XP_011 MSCRCIFLMKHGERVGWPVGVSMPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 MWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB5 TDQSGNYSQECGSFLLAESIKPAPPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDQSGNYSQECGSFLLAESIKPAPPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYEL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB5 QYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB5 DPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFM
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 PLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPA
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 ELVESDGVPKPSFWPTAQNSGGSAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELVESDGVPKPSFWPTAQNSGGSAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDG
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB5 YPALDLDAGLEPSPGLEDPLLDAGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPALDLDAGLEPSPGLEDPLLDAGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGED
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB5 WAGGLPWGGRSPGGVSESEAGSPLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WAGGLPWGGRSPGGVSESEAGSPLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRS
490 500 510 520 530 540
520 530
pF1KB5 YLRQWVVIPPPLSSPGPQAS
::::::::::::::::::::
XP_011 YLRQWVVIPPPLSSPGPQAS
550 560
>>NP_851565 (OMIM: 147050,605383,615207) interleukin-21 (560 aa)
initn: 3838 init1: 3838 opt: 3838 Z-score: 3415.5 bits: 641.8 E(85289): 1.7e-183
Smith-Waterman score: 3838; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:23-560)
10 20 30
pF1KB5 MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILE
::::::::::::::::::::::::::::::::::::::
NP_851 MSCRCIFLMKHGERVGWPVGVSMPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 MWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 MWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB5 TDQSGNYSQECGSFLLAESIKPAPPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 TDQSGNYSQECGSFLLAESIKPAPPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYEL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB5 QYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 QYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB5 DPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 DPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFM
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 PLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 PLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPA
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 ELVESDGVPKPSFWPTAQNSGGSAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 ELVESDGVPKPSFWPTAQNSGGSAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDG
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB5 YPALDLDAGLEPSPGLEDPLLDAGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 YPALDLDAGLEPSPGLEDPLLDAGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGED
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB5 WAGGLPWGGRSPGGVSESEAGSPLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 WAGGLPWGGRSPGGVSESEAGSPLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRS
490 500 510 520 530 540
520 530
pF1KB5 YLRQWVVIPPPLSSPGPQAS
::::::::::::::::::::
NP_851 YLRQWVVIPPPLSSPGPQAS
550 560
>>XP_011544160 (OMIM: 147050,605383,615207) PREDICTED: i (414 aa)
initn: 2635 init1: 2635 opt: 2636 Z-score: 2349.9 bits: 444.2 E(85289): 3.8e-124
Smith-Waterman score: 2636; 99.2% identity (99.5% similar) in 373 aa overlap (167-538:42-414)
140 150 160 170 180 190
pF1KB5 SWRSDYEDPAFYMLKGKLQYELQYRNRGDPWA-VSPRRKLISVDSRSVSLLPLEFRKDSS
: .::::::::::::::::::::::::::
XP_011 MYSTSWPTTFSVSTSQTSLATTPRSVAAFSWLRASPRRKLISVDSRSVSLLPLEFRKDSS
20 30 40 50 60 70
200 210 220 230 240 250
pF1KB5 YELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFWSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFWSL
80 90 100 110 120 130
260 270 280 290 300 310
pF1KB5 KTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLE
140 150 160 170 180 190
320 330 340 350 360 370
pF1KB5 VYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGGSAYSEERDRPYGLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGGSAYSEERDRPYGLVS
200 210 220 230 240 250
380 390 400 410 420 430
pF1KB5 IDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLDAGTTVLSCGCVSAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLDAGTTVLSCGCVSAGS
260 270 280 290 300 310
440 450 460 470 480 490
pF1KB5 PGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGSPLAGLDMDTFDSGFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGSPLAGLDMDTFDSGFV
320 330 340 350 360 370
500 510 520 530
pF1KB5 GSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
:::::::::::::::::::::::::::::::::::::::::::
XP_011 GSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
380 390 400 410
>>NP_001333152 (OMIM: 146710) interleukin-2 receptor sub (551 aa)
initn: 245 init1: 120 opt: 324 Z-score: 295.5 bits: 64.4 E(85289): 1e-09
Smith-Waterman score: 357; 25.1% identity (50.6% similar) in 514 aa overlap (5-471:8-478)
10 20 30 40
pF1KB5 MPRGWAAPLLLLLLQ--GGW------GCPDLVCYTDYLQTVICILEMWN----LHPS
: :::.::: .: : ...:. . .. :. :. :. .
NP_001 MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCV---WSQDGALQDT
10 20 30 40 50
50 60 70 80 90
pF1KB5 TLTL-TWQDQYEELKDEATSCSLHRSAHNATHATYTCHM-----DVFHFMADDIFSVNIT
. . .: :. . .: : ...:...:.. : .. . :: .. .
NP_001 SCQVHAWPDR----RRWNQTCELL----PVSQASWACNLILGAPDSQKLTTVDIVTLRVL
60 70 80 90 100
100 110 120 130 140 150
pF1KB5 DQSGNY--SQECGSFLLAESIKPAPPFNVTVTF--SGQYNISWRSDYEDPAFYMLKGKLQ
. : . .: :... :... :. . . ::::. . : .... .:.
NP_001 CREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQ---ASHYFERHLE
110 120 130 140 150 160
160 170 180 190 200 210
pF1KB5 YELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWS
.: . . : : .: :... ... . . :..::.:::. :. : :::
NP_001 FEARTLSPGHTWEEAP---LLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFT--TWS
170 180 190 200 210 220
220 230 240 250 260
pF1KB5 EWSDPVIFQTQSEELKEG---WNPHLLLLLLLVIVFIPAFWSL----KTHPLWRLWKKIW
::.:. :.:. : . : :::. : .. :: . : .: : : ::.
NP_001 PWSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGP-W--LKKVL
230 240 250 260 270
270 280 290 300 310 320
pF1KB5 A--VPSPERFFMPLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLEVYSCHPPRSPA
.:.: .:: : . .:: .::...:: .::. : .::. : :::
NP_001 KCNTPDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEI-SPLEVL---------
280 290 300 310 320
330 340 350 360 370 380
pF1KB5 KRLQLTELQEPAELVESDGVPKPSFWPTAQNSGGSAYSEERDRPYGLVSI-DTVTVLDAE
.: ..:.: :...: ::.:. . .:. : : .. : . . :.. . .
NP_001 ERDKVTQL-----LLQQDKVPEPA----SLSSNHSLTSCFTNQGYFFFHLPDALEIEACQ
330 340 350 360 370
390 400 410 420 430
pF1KB5 GPCTW-PCSCEDD-----GYPALDLDAGLEPSPGLED-----PLLDAGTTVLSCGCVSAG
:. : : :: : :. . :.: : .: : : ..: . ...
NP_001 VYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCTFPSRD-DLLLFSPSLLGGP
380 390 400 410 420 430
440 450 460 470 480 490
pF1KB5 SPGLGGPLGSLL--DRLKPPLAD--GEDWAGGLPWGGRSPGGVSESEAGSPLAGLDMDTF
:: .: :: .:. : : . .:: : : .::
NP_001 SPPSTAPGGSGAGEERMPPSLQERVPRDW-DPQPLGPPTPGVPDLVDFQPPPELVLREAG
440 450 460 470 480 490
500 510 520 530
pF1KB5 DSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
NP_001 EEVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAYLSLQELQGQDPTHLV
500 510 520 530 540 550
>>NP_001333151 (OMIM: 146710) interleukin-2 receptor sub (551 aa)
initn: 245 init1: 120 opt: 324 Z-score: 295.5 bits: 64.4 E(85289): 1e-09
Smith-Waterman score: 357; 25.1% identity (50.6% similar) in 514 aa overlap (5-471:8-478)
10 20 30 40
pF1KB5 MPRGWAAPLLLLLLQ--GGW------GCPDLVCYTDYLQTVICILEMWN----LHPS
: :::.::: .: : ...:. . .. :. :. :. .
NP_001 MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCV---WSQDGALQDT
10 20 30 40 50
50 60 70 80 90
pF1KB5 TLTL-TWQDQYEELKDEATSCSLHRSAHNATHATYTCHM-----DVFHFMADDIFSVNIT
. . .: :. . .: : ...:...:.. : .. . :: .. .
NP_001 SCQVHAWPDR----RRWNQTCELL----PVSQASWACNLILGAPDSQKLTTVDIVTLRVL
60 70 80 90 100
100 110 120 130 140 150
pF1KB5 DQSGNY--SQECGSFLLAESIKPAPPFNVTVTF--SGQYNISWRSDYEDPAFYMLKGKLQ
. : . .: :... :... :. . . ::::. . : .... .:.
NP_001 CREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQ---ASHYFERHLE
110 120 130 140 150 160
160 170 180 190 200 210
pF1KB5 YELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWS
.: . . : : .: :... ... . . :..::.:::. :. : :::
NP_001 FEARTLSPGHTWEEAP---LLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFT--TWS
170 180 190 200 210 220
220 230 240 250 260
pF1KB5 EWSDPVIFQTQSEELKEG---WNPHLLLLLLLVIVFIPAFWSL----KTHPLWRLWKKIW
::.:. :.:. : . : :::. : .. :: . : .: : : ::.
NP_001 PWSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGP-W--LKKVL
230 240 250 260 270
270 280 290 300 310 320
pF1KB5 A--VPSPERFFMPLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLEVYSCHPPRSPA
.:.: .:: : . .:: .::...:: .::. : .::. : :::
NP_001 KCNTPDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEI-SPLEVL---------
280 290 300 310 320
330 340 350 360 370 380
pF1KB5 KRLQLTELQEPAELVESDGVPKPSFWPTAQNSGGSAYSEERDRPYGLVSI-DTVTVLDAE
.: ..:.: :...: ::.:. . .:. : : .. : . . :.. . .
NP_001 ERDKVTQL-----LLQQDKVPEPA----SLSSNHSLTSCFTNQGYFFFHLPDALEIEACQ
330 340 350 360 370
390 400 410 420 430
pF1KB5 GPCTW-PCSCEDD-----GYPALDLDAGLEPSPGLED-----PLLDAGTTVLSCGCVSAG
:. : : :: : :. . :.: : .: : : ..: . ...
NP_001 VYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCTFPSRD-DLLLFSPSLLGGP
380 390 400 410 420 430
440 450 460 470 480 490
pF1KB5 SPGLGGPLGSLL--DRLKPPLAD--GEDWAGGLPWGGRSPGGVSESEAGSPLAGLDMDTF
:: .: :: .:. : : . .:: : : .::
NP_001 SPPSTAPGGSGAGEERMPPSLQERVPRDW-DPQPLGPPTPGVPDLVDFQPPPELVLREAG
440 450 460 470 480 490
500 510 520 530
pF1KB5 DSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
NP_001 EEVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAYLSLQELQGQDPTHLV
500 510 520 530 540 550
>>NP_000869 (OMIM: 146710) interleukin-2 receptor subuni (551 aa)
initn: 245 init1: 120 opt: 324 Z-score: 295.5 bits: 64.4 E(85289): 1e-09
Smith-Waterman score: 357; 25.1% identity (50.6% similar) in 514 aa overlap (5-471:8-478)
10 20 30 40
pF1KB5 MPRGWAAPLLLLLLQ--GGW------GCPDLVCYTDYLQTVICILEMWN----LHPS
: :::.::: .: : ...:. . .. :. :. :. .
NP_000 MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCV---WSQDGALQDT
10 20 30 40 50
50 60 70 80 90
pF1KB5 TLTL-TWQDQYEELKDEATSCSLHRSAHNATHATYTCHM-----DVFHFMADDIFSVNIT
. . .: :. . .: : ...:...:.. : .. . :: .. .
NP_000 SCQVHAWPDR----RRWNQTCELL----PVSQASWACNLILGAPDSQKLTTVDIVTLRVL
60 70 80 90 100
100 110 120 130 140 150
pF1KB5 DQSGNY--SQECGSFLLAESIKPAPPFNVTVTF--SGQYNISWRSDYEDPAFYMLKGKLQ
. : . .: :... :... :. . . ::::. . : .... .:.
NP_000 CREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQ---ASHYFERHLE
110 120 130 140 150 160
160 170 180 190 200 210
pF1KB5 YELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWS
.: . . : : .: :... ... . . :..::.:::. :. : :::
NP_000 FEARTLSPGHTWEEAP---LLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFT--TWS
170 180 190 200 210 220
220 230 240 250 260
pF1KB5 EWSDPVIFQTQSEELKEG---WNPHLLLLLLLVIVFIPAFWSL----KTHPLWRLWKKIW
::.:. :.:. : . : :::. : .. :: . : .: : : ::.
NP_000 PWSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGP-W--LKKVL
230 240 250 260 270
270 280 290 300 310 320
pF1KB5 A--VPSPERFFMPLYKGCSGDFKKWVGAPFTGSSLELGPWSPEVPSTLEVYSCHPPRSPA
.:.: .:: : . .:: .::...:: .::. : .::. : :::
NP_000 KCNTPDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEI-SPLEVL---------
280 290 300 310 320
330 340 350 360 370 380
pF1KB5 KRLQLTELQEPAELVESDGVPKPSFWPTAQNSGGSAYSEERDRPYGLVSI-DTVTVLDAE
.: ..:.: :...: ::.:. . .:. : : .. : . . :.. . .
NP_000 ERDKVTQL-----LLQQDKVPEPA----SLSSNHSLTSCFTNQGYFFFHLPDALEIEACQ
330 340 350 360 370
390 400 410 420 430
pF1KB5 GPCTW-PCSCEDD-----GYPALDLDAGLEPSPGLED-----PLLDAGTTVLSCGCVSAG
:. : : :: : :. . :.: : .: : : ..: . ...
NP_000 VYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCTFPSRD-DLLLFSPSLLGGP
380 390 400 410 420 430
440 450 460 470 480 490
pF1KB5 SPGLGGPLGSLL--DRLKPPLAD--GEDWAGGLPWGGRSPGGVSESEAGSPLAGLDMDTF
:: .: :: .:. : : . .:: : : .::
NP_000 SPPSTAPGGSGAGEERMPPSLQERVPRDW-DPQPLGPPTPGVPDLVDFQPPPELVLREAG
440 450 460 470 480 490
500 510 520 530
pF1KB5 DSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS
NP_000 EEVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAYLSLQELQGQDPTHLV
500 510 520 530 540 550
>>XP_016885533 (OMIM: 300007) PREDICTED: interleukin-9 r (567 aa)
initn: 195 init1: 108 opt: 229 Z-score: 211.0 bits: 48.8 E(85289): 5.2e-05
Smith-Waterman score: 293; 27.1% identity (51.9% similar) in 362 aa overlap (112-438:186-527)
90 100 110 120 130 140
pF1KB5 HMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFS-GQYNISWRS
.: . .: :: .. ..: :. ..:
XP_016 EAVLVPSDNFTITFHHCMSGREQVSLVDPEYLPRRHVKLDPPSDLQSNISSGHCILTWSI
160 170 180 190 200 210
150 160 170 180 190
pF1KB5 DYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLE-FRKDSSY---
. ::. . :.::: .... . : .. : ... .:. : :: :. : ..
XP_016 S---PALEPMTTLLSYELAFKKQEEAWEAQHRDHIV-----GVTWLILEAFELDPGFIHE
220 230 240 250 260
200 210 220 230 240
pF1KB5 -ELQVRAGPMPGS-----SYQGTWSEWSDPVIFQTQSEE--LKEGWN-PHLLLLLLLVIV
.:.:. . . . : : :::::.:: ::. ... : :. : :. . ...
XP_016 ARLRVQMATLEDDVVEEERYTGQWSEWSQPVCFQAPQRQGPLIPPWGWPGNTLVAVSIFL
270 280 290 300 310 320
250 260 270 280 290 300
pF1KB5 FI--PAFWSLKTHPLWRLWKKIW--AVPSPERFFMPLYKGCSGDFKKWVGAPFTGSSLEL
.. :.. .: : :. :.:. :::: ::.:::. .:.:. :.:: .: :
XP_016 LLTGPTYLLFKLSP--RV-KRIFYQNVPSPAMFFQPLYSVHNGNFQTWMGAHGAGVLLSQ
330 340 350 360 370 380
310 320 330 340 350
pF1KB5 -------GPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQE------PAELVESDGVPKPS
: : : . . .: : : : : . : : :: :..: : .:
XP_016 DCAGTPQGALEPCVQEATALLTCGPAR-PWKSVALEEEQEGPGTRLPGNLSSEDVLPAGC
390 400 410 420 430 440
360 370 380 390 400
pF1KB5 FWPTAQNSGGSAYSEERDRPYGLVSIDTVTVLDAEGP--CTWPCSCEDDGYPALDLDAG-
.:. :: ..: .. .:. . :.:: . : ....: :: .:
XP_016 TEWRVQTL---AYLPQED--WAPTSLTRPAPPDSEGSRSSSSSSSSNNNNYCALGCYGGW
450 460 470 480 490
410 420 430 440 450 460
pF1KB5 -LEPSPGLEDPLLDAGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWG
: :: . .. .:.:: .: ::
XP_016 HLSALPG--NTQSSGPIPALACG-LSCDHQGLETQQGVAWVLAGHCQRPGLHEDLQGMLL
500 510 520 530 540 550
470 480 490 500 510 520
pF1KB5 GRSPGGVSESEAGSPLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVI
XP_016 PSVLSKARSWTF
560
538 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 15:37:24 2016 done: Sat Nov 5 15:37:25 2016
Total Scan time: 10.780 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]