Result of FASTA (omim) for
pFN21AE1305
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1305, 1360 aa
1>>>pF1KE1305 1360 - 1360 aa - 1360 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7175+/-0.000417; mu= 13.1214+/- 0.026
mean_var=162.5707+/-33.262, 0's: 0 Z-trim(116.1): 52 B-trim: 337 in 2/54
Lambda= 0.100590
statistics sampled from 26940 (26990) to 26940 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.316), width: 16
Scan time: 13.580
The best scores are: opt bits E(85289)
NP_000170 (OMIM: 276300,600678,608089,614350) DNA (1360) 9062 1328.4 0
XP_011531100 (OMIM: 276300,600678,608089,614350) P (1299) 8500 1246.8 0
XP_011531101 (OMIM: 276300,600678,608089,614350) P (1261) 8387 1230.4 0
NP_001268421 (OMIM: 276300,600678,608089,614350) D (1230) 7615 1118.4 0
NP_001268422 (OMIM: 276300,600678,608089,614350) D (1058) 7032 1033.7 0
NP_001268423 (OMIM: 276300,600678,608089,614350) D (1058) 7032 1033.7 0
NP_002430 (OMIM: 600887,608089,617100) DNA mismatc (1137) 601 100.5 7.4e-20
NP_001245210 (OMIM: 120435,158320,276300,609309) D ( 868) 590 98.8 1.8e-19
XP_011531169 (OMIM: 120435,158320,276300,609309) P ( 924) 590 98.8 1.9e-19
NP_000242 (OMIM: 120435,158320,276300,609309) DNA ( 934) 590 98.8 1.9e-19
XP_005264389 (OMIM: 120435,158320,276300,609309) P ( 974) 590 98.8 2e-19
NP_002431 (OMIM: 602105) mutS protein homolog 4 [H ( 936) 408 72.4 1.7e-11
NP_002432 (OMIM: 603382) mutS protein homolog 5 is ( 834) 393 70.2 7.1e-11
NP_751898 (OMIM: 603382) mutS protein homolog 5 is ( 834) 393 70.2 7.1e-11
NP_751897 (OMIM: 603382) mutS protein homolog 5 is ( 835) 381 68.5 2.4e-10
NP_079535 (OMIM: 603382) mutS protein homolog 5 is ( 822) 334 61.6 2.7e-08
NP_015627 (OMIM: 194190,602952) histone-lysine N-m ( 629) 265 51.5 2.2e-05
XP_005248062 (OMIM: 194190,602952) PREDICTED: hist ( 647) 265 51.5 2.3e-05
NP_579889 (OMIM: 194190,602952) histone-lysine N-m ( 647) 265 51.5 2.3e-05
XP_006713977 (OMIM: 194190,602952) PREDICTED: hist ( 647) 265 51.5 2.3e-05
NP_060248 (OMIM: 607083) histone-lysine N-methyltr ( 645) 262 51.1 3.1e-05
XP_005248059 (OMIM: 194190,602952) PREDICTED: hist (1296) 265 51.8 3.9e-05
NP_579890 (OMIM: 194190,602952) histone-lysine N-m (1365) 265 51.8 4.1e-05
XP_011511859 (OMIM: 194190,602952) PREDICTED: hist (1365) 265 51.8 4.1e-05
XP_005248058 (OMIM: 194190,602952) PREDICTED: hist (1365) 265 51.8 4.1e-05
NP_579877 (OMIM: 194190,602952) histone-lysine N-m (1365) 265 51.8 4.1e-05
NP_001035889 (OMIM: 194190,602952) histone-lysine (1365) 265 51.8 4.1e-05
NP_579878 (OMIM: 194190,602952) histone-lysine N-m (1365) 265 51.8 4.1e-05
NP_075447 (OMIM: 607083) histone-lysine N-methyltr (1437) 262 51.4 5.7e-05
>>NP_000170 (OMIM: 276300,600678,608089,614350) DNA mism (1360 aa)
initn: 9062 init1: 9062 opt: 9062 Z-score: 7112.3 bits: 1328.4 E(85289): 0
Smith-Waterman score: 9062; 100.0% identity (100.0% similar) in 1360 aa overlap (1-1360:1-1360)
10 20 30 40 50 60
pF1KE1 MSRQSTLYSFFPKSPALSDANKASARASREGGRAAAAPGASPSPGGDAAWSEAGPGPRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSRQSTLYSFFPKSPALSDANKASARASREGGRAAAAPGASPSPGGDAAWSEAGPGPRPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ARSASPPKAKNLNGGLRRSVAPAAPTSCDFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ARSASPPKAKNLNGGLRRSVAPAAPTSCDFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 REKGKSVRVHVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGHFYSAKPEILRAMQRAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 REKGKSVRVHVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGHFYSAKPEILRAMQRAD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EALNKDKIKRLELAVCDEPSEPEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQGSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EALNKDKIKRLELAVCDEPSEPEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQGSRR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 KRMVTGNGSLKRKSSRKETPSATKQATSISSETKNTLRAFSAPQNSESQAHVSGGGDDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KRMVTGNGSLKRKSSRKETPSATKQATSISSETKNTLRAFSAPQNSESQAHVSGGGDDSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 RPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLNSCTPGMRKWWQIKSQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLNSCTPGMRKWWQIKSQN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 FDLVICYKVGKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEIAFGRYSDSLVQKGYKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FDLVICYKVGKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEIAFGRYSDSLVQKGYKV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 ARVEQTETPEMMEARCRKMAHISKYDRVVRREICRIITKGTQTYSVLEGDPSENYSKYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ARVEQTETPEMMEARCRKMAHISKYDRVVRREICRIITKGTQTYSVLEGDPSENYSKYLL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 SLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 LSKETKTILKSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSKETKTILKSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 GMTSESDSIGLTPGEKSELALSALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GMTSESDSIGLTPGEKSELALSALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 RSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 PLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE1 RAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE1 RFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE1 RIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLIN
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE1 AEERRDVSLKDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AEERRDVSLKDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVIL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE1 LPEDTPPFLELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LPEDTPPFLELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE1 STLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 STLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE1 LMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE1 AVRLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AVRLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKA
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360
pF1KE1 REFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL
::::::::::::::::::::::::::::::::::::::::
NP_000 REFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL
1330 1340 1350 1360
>>XP_011531100 (OMIM: 276300,600678,608089,614350) PREDI (1299 aa)
initn: 8483 init1: 8483 opt: 8500 Z-score: 6671.8 bits: 1246.8 E(85289): 0
Smith-Waterman score: 8500; 99.3% identity (99.5% similar) in 1286 aa overlap (75-1360:14-1299)
50 60 70 80 90 100
pF1KE1 GGDAAWSEAGPGPRPLARSASPPKAKNLNGGLRRSVAPAAPTSCDFSPGDLVWAKMEGYP
:.:. : : :::::::::::::::::
XP_011 MPAGGRTGRVRWCGVRKEVPRPARRYCDFSPGDLVWAKMEGYP
10 20 30 40
110 120 130 140 150 160
pF1KE1 WWPCLVYNHPFDGTFIREKGKSVRVHVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WWPCLVYNHPFDGTFIREKGKSVRVHVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGH
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE1 FYSAKPEILRAMQRADEALNKDKIKRLELAVCDEPSEPEEEEEMEVGTTYVTDKSEEDNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYSAKPEILRAMQRADEALNKDKIKRLELAVCDEPSEPEEEEEMEVGTTYVTDKSEEDNE
110 120 130 140 150 160
230 240 250 260 270 280
pF1KE1 IESEEEVQPKTQGSRRSSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IESEEEVQPKTQGSRRSSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGD
170 180 190 200 210 220
290 300 310 320 330 340
pF1KE1 SESEGLNSPVKVARKRKRMVTGNGSLKRKSSRKETPSATKQATSISSETKNTLRAFSAPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SESEGLNSPVKVARKRKRMVTGNGSLKRKSSRKETPSATKQATSISSETKNTLRAFSAPQ
230 240 250 260 270 280
350 360 370 380 390 400
pF1KE1 NSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLN
290 300 310 320 330 340
410 420 430 440 450 460
pF1KE1 SCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEI
350 360 370 380 390 400
470 480 490 500 510 520
pF1KE1 AFGRYSDSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRREICRIITKGTQTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFGRYSDSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRREICRIITKGTQTY
410 420 430 440 450 460
530 540 550 560 570 580
pF1KE1 SVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRT
470 480 490 500 510 520
590 600 610 620 630 640
pF1KE1 LVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFR
530 540 550 560 570 580
650 660 670 680 690 700
pF1KE1 EKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLKKCLIDQELLSMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLKKCLIDQELLSMA
590 600 610 620 630 640
710 720 730 740 750 760
pF1KE1 NFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDT
650 660 670 680 690 700
770 780 790 800 810 820
pF1KE1 CHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSK
710 720 730 740 750 760
830 840 850 860 870 880
pF1KE1 IHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKS
770 780 790 800 810 820
890 900 910 920 930 940
pF1KE1 KILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADI
830 840 850 860 870 880
950 960 970 980 990 1000
pF1KE1 RENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCK
890 900 910 920 930 940
1010 1020 1030 1040 1050 1060
pF1KE1 RYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLA
950 960 970 980 990 1000
1070 1080 1090 1100 1110 1120
pF1KE1 NYSRGGDGPMCRPVILLPEDTPPFLELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYSRGGDGPMCRPVILLPEDTPPFLELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQEN
1010 1020 1030 1040 1050 1060
1130 1140 1150 1160 1170 1180
pF1KE1 GKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIM
1070 1080 1090 1100 1110 1120
1190 1200 1210 1220 1230 1240
pF1KE1 SGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTL
1130 1140 1150 1160 1170 1180
1250 1260 1270 1280 1290 1300
pF1KE1 FSTHYHSLVEDYSQNVAVRLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSTHYHSLVEDYSQNVAVRLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAAR
1190 1200 1210 1220 1230 1240
1310 1320 1330 1340 1350 1360
pF1KE1 LANLPEEVIQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LANLPEEVIQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL
1250 1260 1270 1280 1290
>>XP_011531101 (OMIM: 276300,600678,608089,614350) PREDI (1261 aa)
initn: 8387 init1: 8387 opt: 8387 Z-score: 6583.3 bits: 1230.4 E(85289): 0
Smith-Waterman score: 8387; 100.0% identity (100.0% similar) in 1261 aa overlap (100-1360:1-1261)
70 80 90 100 110 120
pF1KE1 KNLNGGLRRSVAPAAPTSCDFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFIREKGKSVRV
::::::::::::::::::::::::::::::
XP_011 MEGYPWWPCLVYNHPFDGTFIREKGKSVRV
10 20 30
130 140 150 160 170 180
pF1KE1 HVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGHFYSAKPEILRAMQRADEALNKDKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGHFYSAKPEILRAMQRADEALNKDKIK
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE1 RLELAVCDEPSEPEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQGSRRSSRQIKKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLELAVCDEPSEPEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQGSRRSSRQIKKRR
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE1 VISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKRKRMVTGNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKRKRMVTGNGS
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE1 LKRKSSRKETPSATKQATSISSETKNTLRAFSAPQNSESQAHVSGGGDDSSRPTVWYHET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKRKSSRKETPSATKQATSISSETKNTLRAFSAPQNSESQAHVSGGGDDSSRPTVWYHET
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE1 LEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLNSCTPGMRKWWQIKSQNFDLVICYKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLNSCTPGMRKWWQIKSQNFDLVICYKV
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE1 GKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETP
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE1 EMMEARCRKMAHISKYDRVVRREICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMMEARCRKMAHISKYDRVVRREICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDS
400 410 420 430 440 450
550 560 570 580 590 600
pF1KE1 SGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTIL
460 470 480 490 500 510
610 620 630 640 650 660
pF1KE1 KSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSI
520 530 540 550 560 570
670 680 690 700 710 720
pF1KE1 GLTPGEKSELALSALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLTPGEKSELALSALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKA
580 590 600 610 620 630
730 740 750 760 770 780
pF1KE1 YQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAIN
640 650 660 670 680 690
790 800 810 820 830 840
pF1KE1 DRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETT
700 710 720 730 740 750
850 860 870 880 890 900
pF1KE1 YSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVEL
760 770 780 790 800 810
910 920 930 940 950 960
pF1KE1 NRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVY
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KE1 WGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSL
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KE1 KDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFL
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KE1 ELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGL
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KE1 LAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHATAHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHATAHSL
1060 1070 1080 1090 1100 1110
1210 1220 1230 1240 1250 1260
pF1KE1 VLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMAC
1120 1130 1140 1150 1160 1170
1270 1280 1290 1300 1310 1320
pF1KE1 MVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQS
1180 1190 1200 1210 1220 1230
1330 1340 1350 1360
pF1KE1 LRLFREVCLASERSTVDAEAVHKLLTLIKEL
:::::::::::::::::::::::::::::::
XP_011 LRLFREVCLASERSTVDAEAVHKLLTLIKEL
1240 1250 1260
>>NP_001268421 (OMIM: 276300,600678,608089,614350) DNA m (1230 aa)
initn: 7615 init1: 7615 opt: 7615 Z-score: 5978.0 bits: 1118.4 E(85289): 0
Smith-Waterman score: 7874; 90.4% identity (90.4% similar) in 1360 aa overlap (1-1360:1-1230)
10 20 30 40 50 60
pF1KE1 MSRQSTLYSFFPKSPALSDANKASARASREGGRAAAAPGASPSPGGDAAWSEAGPGPRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSRQSTLYSFFPKSPALSDANKASARASREGGRAAAAPGASPSPGGDAAWSEAGPGPRPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ARSASPPKAKNLNGGLRRSVAPAAPTSCDFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFI
::::::::::::::::::::
NP_001 ARSASPPKAKNLNGGLRRSV----------------------------------------
70 80
130 140 150 160 170 180
pF1KE1 REKGKSVRVHVQFFDDSPTRGWVSKRLLKPYTGSKSKEAQKGGHFYSAKPEILRAMQRAD
NP_001 ------------------------------------------------------------
190 200 210 220 230 240
pF1KE1 EALNKDKIKRLELAVCDEPSEPEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQGSRR
::::::::::::::::::::::::::::::
NP_001 ------------------------------GTTYVTDKSEEDNEIESEEEVQPKTQGSRR
90 100 110
250 260 270 280 290 300
pF1KE1 SSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKR
120 130 140 150 160 170
310 320 330 340 350 360
pF1KE1 KRMVTGNGSLKRKSSRKETPSATKQATSISSETKNTLRAFSAPQNSESQAHVSGGGDDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRMVTGNGSLKRKSSRKETPSATKQATSISSETKNTLRAFSAPQNSESQAHVSGGGDDSS
180 190 200 210 220 230
370 380 390 400 410 420
pF1KE1 RPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLNSCTPGMRKWWQIKSQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLYVPEDFLNSCTPGMRKWWQIKSQN
240 250 260 270 280 290
430 440 450 460 470 480
pF1KE1 FDLVICYKVGKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEIAFGRYSDSLVQKGYKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDLVICYKVGKFYELYHMDALIGVSELGLVFMKGNWAHSGFPEIAFGRYSDSLVQKGYKV
300 310 320 330 340 350
490 500 510 520 530 540
pF1KE1 ARVEQTETPEMMEARCRKMAHISKYDRVVRREICRIITKGTQTYSVLEGDPSENYSKYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARVEQTETPEMMEARCRKMAHISKYDRVVRREICRIITKGTQTYSVLEGDPSENYSKYLL
360 370 380 390 400 410
550 560 570 580 590 600
pF1KE1 SLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGN
420 430 440 450 460 470
610 620 630 640 650 660
pF1KE1 LSKETKTILKSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSKETKTILKSSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLK
480 490 500 510 520 530
670 680 690 700 710 720
pF1KE1 GMTSESDSIGLTPGEKSELALSALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMTSESDSIGLTPGEKSELALSALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTT
540 550 560 570 580 590
730 740 750 760 770 780
pF1KE1 RSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCA
600 610 620 630 640 650
790 800 810 820 830 840
pF1KE1 PLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLCNHYAINDRLDAIEDLMVVPDKISEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDS
660 670 680 690 700 710
850 860 870 880 890 900
pF1KE1 RAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAIMYEETTYSKKKIIDFLSALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEG
720 730 740 750 760 770
910 920 930 940 950 960
pF1KE1 RFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRN
780 790 800 810 820 830
970 980 990 1000 1010 1020
pF1KE1 RIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLIN
840 850 860 870 880 890
1030 1040 1050 1060 1070 1080
pF1KE1 AEERRDVSLKDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEERRDVSLKDCMRRLFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVIL
900 910 920 930 940 950
1090 1100 1110 1120 1130 1140
pF1KE1 LPEDTPPFLELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPEDTPPFLELKGSRHPCITKTFFGDDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGK
960 970 980 990 1000 1010
1150 1160 1170 1180 1190 1200
pF1KE1 STLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASI
1020 1030 1040 1050 1060 1070
1210 1220 1230 1240 1250 1260
pF1KE1 LMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNV
1080 1090 1100 1110 1120 1130
1270 1280 1290 1300 1310 1320
pF1KE1 AVRLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVRLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKA
1140 1150 1160 1170 1180 1190
1330 1340 1350 1360
pF1KE1 REFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL
::::::::::::::::::::::::::::::::::::::::
NP_001 REFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL
1200 1210 1220 1230
>>NP_001268422 (OMIM: 276300,600678,608089,614350) DNA m (1058 aa)
initn: 7032 init1: 7032 opt: 7032 Z-score: 5521.7 bits: 1033.7 E(85289): 0
Smith-Waterman score: 7032; 100.0% identity (100.0% similar) in 1058 aa overlap (303-1360:1-1058)
280 290 300 310 320 330
pF1KE1 GSSDEISSGVGDSESEGLNSPVKVARKRKRMVTGNGSLKRKSSRKETPSATKQATSISSE
::::::::::::::::::::::::::::::
NP_001 MVTGNGSLKRKSSRKETPSATKQATSISSE
10 20 30
340 350 360 370 380 390
pF1KE1 TKNTLRAFSAPQNSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKNTLRAFSAPQNSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFD
40 50 60 70 80 90
400 410 420 430 440 450
pF1KE1 ASTLYVPEDFLNSCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLVFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASTLYVPEDFLNSCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLVFM
100 110 120 130 140 150
460 470 480 490 500 510
pF1KE1 KGNWAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGNWAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRRE
160 170 180 190 200 210
520 530 540 550 560 570
pF1KE1 ICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQ
220 230 240 250 260 270
580 590 600 610 620 630
pF1KE1 FSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASK
280 290 300 310 320 330
640 650 660 670 680 690
pF1KE1 TLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLK
340 350 360 370 380 390
700 710 720 730 740 750
pF1KE1 KCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNG
400 410 420 430 440 450
760 770 780 790 800 810
pF1KE1 STEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELL
460 470 480 490 500 510
820 830 840 850 860 870
pF1KE1 KKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKII
520 530 540 550 560 570
880 890 900 910 920 930
pF1KE1 GIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAG
580 590 600 610 620 630
940 950 960 970 980 990
pF1KE1 FDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPE
640 650 660 670 680 690
1000 1010 1020 1030 1040 1050
pF1KE1 EYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVE
700 710 720 730 740 750
1060 1070 1080 1090 1100 1110
pF1KE1 CIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELKGSRHPCITKTFFGDDFIPND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELKGSRHPCITKTFFGDDFIPND
760 770 780 790 800 810
1120 1130 1140 1150 1160 1170
pF1KE1 ILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDR
820 830 840 850 860 870
1180 1190 1200 1210 1220 1230
pF1KE1 VFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVV
880 890 900 910 920 930
1240 1250 1260 1270 1280 1290
pF1KE1 KELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVENECEDPSQETITFLYKFIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVENECEDPSQETITFLYKFIKG
940 950 960 970 980 990
1300 1310 1320 1330 1340 1350
pF1KE1 ACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAEAVHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAEAVHK
1000 1010 1020 1030 1040 1050
1360
pF1KE1 LLTLIKEL
::::::::
NP_001 LLTLIKEL
>>NP_001268423 (OMIM: 276300,600678,608089,614350) DNA m (1058 aa)
initn: 7032 init1: 7032 opt: 7032 Z-score: 5521.7 bits: 1033.7 E(85289): 0
Smith-Waterman score: 7032; 100.0% identity (100.0% similar) in 1058 aa overlap (303-1360:1-1058)
280 290 300 310 320 330
pF1KE1 GSSDEISSGVGDSESEGLNSPVKVARKRKRMVTGNGSLKRKSSRKETPSATKQATSISSE
::::::::::::::::::::::::::::::
NP_001 MVTGNGSLKRKSSRKETPSATKQATSISSE
10 20 30
340 350 360 370 380 390
pF1KE1 TKNTLRAFSAPQNSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKNTLRAFSAPQNSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFD
40 50 60 70 80 90
400 410 420 430 440 450
pF1KE1 ASTLYVPEDFLNSCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLVFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASTLYVPEDFLNSCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLVFM
100 110 120 130 140 150
460 470 480 490 500 510
pF1KE1 KGNWAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGNWAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRRE
160 170 180 190 200 210
520 530 540 550 560 570
pF1KE1 ICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQ
220 230 240 250 260 270
580 590 600 610 620 630
pF1KE1 FSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASK
280 290 300 310 320 330
640 650 660 670 680 690
pF1KE1 TLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLK
340 350 360 370 380 390
700 710 720 730 740 750
pF1KE1 KCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTNG
400 410 420 430 440 450
760 770 780 790 800 810
pF1KE1 STEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVVELL
460 470 480 490 500 510
820 830 840 850 860 870
pF1KE1 KKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLSALEGFKVMCKII
520 530 540 550 560 570
880 890 900 910 920 930
pF1KE1 GIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAG
580 590 600 610 620 630
940 950 960 970 980 990
pF1KE1 FDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPE
640 650 660 670 680 690
1000 1010 1020 1030 1040 1050
pF1KE1 EYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLKDCMRRLFYNFDKNYKDWQSAVE
700 710 720 730 740 750
1060 1070 1080 1090 1100 1110
pF1KE1 CIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELKGSRHPCITKTFFGDDFIPND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELKGSRHPCITKTFFGDDFIPND
760 770 780 790 800 810
1120 1130 1140 1150 1160 1170
pF1KE1 ILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDR
820 830 840 850 860 870
1180 1190 1200 1210 1220 1230
pF1KE1 VFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVV
880 890 900 910 920 930
1240 1250 1260 1270 1280 1290
pF1KE1 KELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVENECEDPSQETITFLYKFIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVENECEDPSQETITFLYKFIKG
940 950 960 970 980 990
1300 1310 1320 1330 1340 1350
pF1KE1 ACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAEAVHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAEAVHK
1000 1010 1020 1030 1040 1050
1360
pF1KE1 LLTLIKEL
::::::::
NP_001 LLTLIKEL
>>NP_002430 (OMIM: 600887,608089,617100) DNA mismatch re (1137 aa)
initn: 816 init1: 427 opt: 601 Z-score: 477.5 bits: 100.5 E(85289): 7.4e-20
Smith-Waterman score: 1053; 26.9% identity (58.9% similar) in 1121 aa overlap (248-1331:85-1101)
220 230 240 250 260 270
pF1KE1 KSEEDNEIESEEEVQPKTQGSRRSSRQIKKRRVISDSESDIGGSDVEFKPDTKEEGSSDE
:: :.: : . : ..::.::
NP_002 AAAAAAAAPPAPPAPAFPPQLPPHIATEIDRRKKRPLEND-GPVKKKVKKVQQKEGGSDL
60 70 80 90 100 110
280 290 300 310 320 330
pF1KE1 ISSGVGDSESEGLNSPVKVARKRKRMVTGNGSLKRKSSRKETPSATKQATSISSETKNTL
:: .:: : : : :. . . .::. . :.. :. :.. .
NP_002 GMSG--NSE------PKKCLRTRN-VSKSLEKLKEFCCDSALPQSRVQTESLQERFAVLP
120 130 140 150 160
340 350 360 370 380 390
pF1KE1 RAFSAPQNSESQAHVSGGGDDSSRPTVWYHETLEWLKEEKRRDEHRRRPDHPDFDASTLY
. . . : .:. . ...::.: :: :.. . .: ... ..
NP_002 KCTDFDDISLLHAKNAVSSEDSKRQINQKDTTLFDLSQFGSSNT-----SHENLQKTASK
170 180 190 200 210
400 410 420 430 440 450
pF1KE1 VPEDFLNSC-TPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSELGLV-FMKGN
. .: :: .. ..:.:. : :.: . : :... :: :.. ::.. . :
NP_002 SANKRSKSIYTPLELQYIEMKQQHKDAVLCVECGYKYRFFGEDAEIAARELNIYCHLDHN
220 230 240 250 260 270
460 470 480 490 500
pF1KE1 WAHSGFPEIAFGRYSDSLVQKGYKVARVEQTETPEMM---EARC----RKMAHISKYDRV
. ...: . . :: :::::. :.:::: . . : ::.. . . .
NP_002 FMTASIPTHRLFVHVRRLVAKGYKVGVVKQTETAALKAIGDNRSSLFSRKLTALYTKSTL
280 290 300 310 320 330
510 520 530 540 550 560
pF1KE1 VRREICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRA---YGVCFVDTSL
. ... .: : .. .: : ... ..::: ..:..:. . .. :. :. .
NP_002 IGEDVNPLI-KLDDAVNVDEI-MTDTSTSYLLCISENKENVRDKKKGNIFIGIVGVQPAT
340 350 360 370 380 390
570 580 590 600 610 620
pF1KE1 GKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIP--
:. . .:.:. :...: .. ::..:. .. ::..:..... . : :.:. :
NP_002 GEVVFDSFQDSASRSELETRMSSLQPVELLLPSA-LSEQTEALIHRATSVSVQDDRIRVE
400 410 420 430 440 450
630 640 650 660 670 680
pF1KE1 --GSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELAL
. ... :...... : : : : . . :...:. ..: :: ..
NP_002 RMDNIYFEYSHAFQAVTE---FYAK--DTVDIKGSQIISGI------VNL---EKP--VI
460 470 480 490 500
690 700 710 720 730 740
pF1KE1 SALGGCVFYLKKCLIDQELLSMANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLN
.:.. . :::. ... : . ::.. ... .. :.....::
NP_002 CSLAAIIKYLKEFNLEKMLSKPENFKQ-----------------LSSKMEFMTINGTTLR
510 520 530 540
750 760 770 780 790 800
pF1KE1 NLEIFLNGTNGSTEGTLLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVV
::::. : :. .:.:.:: .: .: ::.: ::.:. :: . :: ::::. ...
NP_002 NLEILQNQTDMKTKGSLLWVLDHTKTSFGRRKLKKWVTQPLLKLREINARLDAVSEVLHS
550 560 570 580 590 600
810 820 830 840 850 860
pF1KE1 PDKI-SEVVELLKKLPDLERLLSKIHNVGSPLKSQNHPDSRAIMYEETTYSKKKIIDFLS
... ... . :.::::.:: : .:.. . ..:. .. .: : :. .: .
NP_002 ESSVFGQIENHLRKLPDIERGLCSIYH--KKCSTQEF-----FLIVKTLYHLKS--EFQA
610 620 630 640 650
870 880 890 900 910 920
pF1KE1 ALEGFKVMCKIIGIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFDHEK
:. : . ..: .:. :: :. .:.: .... .. :.
NP_002 -------------IIPAVNSHIQSDLLRTVI-LE-------IPELLSPVEHYLKILN-EQ
660 670 680 690
930 940 950 960 970
pF1KE1 ARKTGLITPKAGFDSDYDQALADIRENE-QSLLE----YLEKQRNRIGCRTIVYWGIGRN
: :.: : : . : : :..: :.... .:.. :. . . : .. .
NP_002 AAKVGDKTEL--FKDLSDFPLIKKRKDEIQGVIDEIRMHLQEIRKILKNPSAQYVTVSGQ
700 710 720 730 740 750
980 990 1000 1010 1020 1030
pF1KE1 RYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLKDCMRR
....:: .: .. .: .. .. :. .:. . : . : . .. :. . :: .
NP_002 EFMIEI-KNSAVSCIPTDWVKVGSTKAVSRFHSPFI---VENYRHLNQLREQLVLDCSAE
760 770 780 790 800
1040 1050 1060 1070 1080 1090
pF1KE1 ---LFYNFDKNYKDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELK
.. .:...:.. .::. .:..: .. ::. .. :: .:::.. :. . .:
NP_002 WLDFLEKFSEHYHSLCKAVHHLATVDCIFSLAKVAKQGD--YCRPTV--QEERK--IVIK
810 820 830 840 850 860
1100 1110 1120 1130 1140 1150
pF1KE1 GSRHPCITKTFFG--DDFIPNDILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLL
..::: : ...: :...::. .. :. :. ...:::::::::. ..:..:.
NP_002 NGRHPVID-VLLGEQDQYVPNNTDLS-EDSER------VMIITGPNMGGKSSYIKQVALI
870 880 890 900 910
1160 1170 1180 1190 1200 1210
pF1KE1 AVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHATAHSLV
..:::.: ::::: . .: .:::.::.: :..:.:::. ::..:: :. .::..:::
NP_002 TIMAQIGSYVPAEEATIGIVDGIFTRMGAADNIYKGQSTFMEELTDTAEIIRKATSQSLV
920 930 940 950 960 970
1220 1230 1240 1250 1260
pF1KE1 LVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVE---DYSQNVAVRLGHM
..:::::::.: :: ::: :... . . .: ::: ::: . : .::..:. ::
NP_002 ILDELGRGTSTHDGIAIAYATLEYFIRDVKSLTLFVTHYPPVCELEKNYSHQVGNY--HM
980 990 1000 1010 1020 1030
1270 1280 1290 1300 1310 1320
pF1KE1 ACMV-ENECE-DPSQ-----ETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKA
. .: :.: . ::. . .::::.. .: .:::.:.:.::..: :...:. .:.
NP_002 GFLVSEDESKLDPGAAEQVPDFVTFLYQITRGIAARSYGLNVAKLADVPGEILKKAAHKS
1040 1050 1060 1070 1080 1090
1330 1340 1350 1360
pF1KE1 REFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL
.:.: . .. :
NP_002 KELEGLINTKRKRLKYFAKLWTMHNAQDLQKWTEEFNMEETQTSLLH
1100 1110 1120 1130
>>NP_001245210 (OMIM: 120435,158320,276300,609309) DNA m (868 aa)
initn: 678 init1: 428 opt: 590 Z-score: 470.5 bits: 98.8 E(85289): 1.8e-19
Smith-Waterman score: 833; 27.8% identity (57.7% similar) in 823 aa overlap (521-1325:63-787)
500 510 520 530 540 550
pF1KE1 MMEARCRKMAHISKYDRVVRREICRIITKGTQTYSVLEGDPSENYSKYLLSLKEKEEDSS
.: ..: :. . . : ....: . :..
NP_001 RVEVYKNRAGNKASKENDWYLAYKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQ
40 50 60 70 80 90
560 570 580 590 600 610
pF1KE1 GHTRAYGVCFVDTSLGKFFIGQFSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILK
: :: .::. :. . .: :. . : ...:. . : . .. :. . .
NP_001 ---RQVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETAGDM-----
100 110 120 130 140
620 630 640 650 660 670
pF1KE1 SSLSCSLQEGLIPGSQFWDASKTLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIG
..: .:.: : .. :. . . . .. : ..::: .:. . .
NP_001 GKLRQIIQRGGILITERKKADFSTKDIYQD--------------LNRLLKGKKGEQMNSA
150 160 170 180 190
680 690 700 710 720
pF1KE1 LTPGEKSELALSALGGCVFYLKKCLIDQELLSM-ANFEEYIPLDSDTVSTTRSGAIFTKA
. : ....:.:.:.. . .: :::: .:: .. : :.
NP_001 VLPEMENQVAVSSLSAVIKFL-------ELLSDDSNFGQFELTTFD----------FS--
200 210 220 230
730 740 750 760 770 780
pF1KE1 YQRMVLDAVTLNNLEIFLNGTNGSTEGT--LLERVDTCHTPFGKRLLKQWLCAPLCNHYA
: : :: ... :..: .:. .: :. : .. :.:: :.::..::. :: ..
NP_001 -QYMKLDIAAVRALNLF-QGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNR
240 250 260 270 280
790 800 810 820 830
pF1KE1 INDRLDAIEDLMVVPDKISEVVE--LLKKLPDLERLLSKIHNVGSPLKS--------QNH
:..::. .: . : .. .... ::...:::.:: .:.. .. :.. ..
NP_001 IEERLNLVEAF-VEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQL
290 300 310 320 330 340
840 850 860 870 880 890
pF1KE1 PDS-RAIMYEETTYSKKKIIDFLSALEGFKV-MCKIIGIMEEVADGFKSKILKQVISLQT
:. .:. .: ..: . :.. : .. . :. ..: . : . :: . .
NP_001 PNVIQALEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLD------MDQVENHEF
350 360 370 380 390 400
900 910 920 930 940 950
pF1KE1 KNPEGRFPDLTVELNRWDTAFDHEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYL
. :.:. :: . : :: .. ::. :. : : . .:. . .. . :
NP_001 LVKPSFDPNLS-ELR--EIMNDLEKKMQSTLIS--AARDLGLDPG-KQIKLDSSAQFGYY
410 420 430 440 450
960 970 980 990 1000 1010
pF1KE1 EKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKL
:. :. . :: .::.: .. :. : . :. :.
NP_001 F----RVTCKE---EKVLRNN------KNFSTVDIQ-----KNGVKFTNSKLTSLNEEYT
460 470 480 490
1020 1030 1040 1050 1060 1070
pF1KE1 ANLINAEERRDVSLKDCMRRLFYNFDKNY-KDWQSAVECIAVLDVLLCLANYSRGGDGPM
: . :: .:. .:. . :....: . :. . .: ::... .:. : :. :.
NP_001 KNKTEYEEAQDAIVKEIV-----NISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPY
500 510 520 530 540 550
1080 1090 1100 1110 1120 1130
pF1KE1 CRPVILLPEDTPPFLELKGSRHPCITKTFFGDD--FIPNDILIGCEEEEQENGKAYCVLV
::.:: : . ::.::: :. :. :::::. . :. : . ..
NP_001 VRPAIL--EKGQGRIILKASRHACVE---VQDEIAFIPNDVYF-------EKDKQMFHII
560 570 580 590 600
1140 1150 1160 1170 1180 1190
pF1KE1 TGPNMGGKSTLMRQAGLLAVMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFV
:::::::::: .::.:....:::.::.:: : ... .: ...:.::.: ..: :::..
NP_001 TGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMA
610 620 630 640 650 660
1200 1210 1220 1230 1240 1250
pF1KE1 ELSETASILMHATAHSLVLVDELGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSL
:. :::::: :: ::...:::::::.:.:: ..: :. . .: : .:.::.: :
NP_001 EMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHEL
670 680 690 700 710 720
1260 1270 1280 1290 1300 1310
pF1KE1 VEDYSQNVAVRLGHMACMVENECEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEV
. .: .: :.. .. ..::.:.::. ::.: .:.:...:.:::.:..:
NP_001 TALANQIPTVNNLHVTALT-------TEETLTMLYQVKKGVCDQSFGIHVAELANFPKHV
730 740 750 760 770
1320 1330 1340 1350 1360
pF1KE1 IQKGHRKAREFEKMNQSLRLFREVCLASERSTVDAEAVHKLLTLIKEL
:. ...:: :.:.
NP_001 IECAKQKALELEEFQYIGESQGYDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMS
780 790 800 810 820 830
>>XP_011531169 (OMIM: 120435,158320,276300,609309) PREDI (924 aa)
initn: 678 init1: 428 opt: 590 Z-score: 470.1 bits: 98.8 E(85289): 1.9e-19
Smith-Waterman score: 835; 26.8% identity (56.9% similar) in 921 aa overlap (430-1325:40-853)
400 410 420 430 440 450
pF1KE1 EDFLNSCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSEL----GLVFMKGN
: :: . :::... :. :.. . :
XP_011 QLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKTQGVIKYMGP
10 20 30 40 50 60
460 470 480 490 500 510
pF1KE1 WAHSGFPEIAFGRYS-DSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRREIC
. ... ....... .:.: : ..: ..:. . : . :: . .
XP_011 AGAKNLQSVVLSKMNFESFV-KDLLLVRQYRVEV-----YKNRAGNKASKENDWY---LA
70 80 90 100 110 120
520 530 540 550 560 570
pF1KE1 RIITKG--TQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQ
. : .: ..: :. . . : ....: . :.. : :: .::. :. . .
XP_011 YKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQ---RQVGVGYVDSIQRKLGLCE
130 140 150 160 170
580 590 600 610 620 630
pF1KE1 FSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASK
: :. . : ...:. . : . .. :. . . ..: .:.: : .. :.
XP_011 FPDNDQFSNLEALLIQIGPKECVLPGGETAGDM-----GKLRQIIQRGGILITERKKADF
180 190 200 210 220 230
640 650 660 670 680 690
pF1KE1 TLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLK
. . . .. : ..::: .:. . .. : ....:.:.:.. . .:
XP_011 STKDIYQD--------------LNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFL-
240 250 260 270
700 710 720 730 740 750
pF1KE1 KCLIDQELLSM-ANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTN
:::: .:: .. : :. : : :: ... :..: .:.
XP_011 ------ELLSDDSNFGQFELTTFD----------FS---QYMKLDIAAVRALNLF-QGSV
280 290 300 310
760 770 780 790 800
pF1KE1 GSTEGT--LLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVV
.: :. : .. :.:: :.::..::. :: .. :..::. .: . : .. ...
XP_011 EDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAF-VEDAELRQTL
320 330 340 350 360 370
810 820 830 840 850
pF1KE1 E--LLKKLPDLERLLSKIHNVGSPLKS--------QNHPDS-RAIMYEETTYSKKKIIDF
. ::...:::.:: .:.. .. :.. .. :. .:. .: ..: . :
XP_011 QEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVF
380 390 400 410 420 430
860 870 880 890 900 910
pF1KE1 LSALEGFKV-MCKIIGIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFD
.. : .. . :. ..: . : . :: . . . :.:. :: . :
XP_011 VTPLTDLRSDFSKFQEMIETTLD------MDQVENHEFLVKPSFDPNLS-ELR--EIMND
440 450 460 470 480
920 930 940 950 960 970
pF1KE1 HEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRY
:: .. ::. :. : : . .:. . .. . : :. :. . ::
XP_011 LEKKMQSTLIS--AARDLGLDPG-KQIKLDSSAQFGYYF----RVTCKE---EKVLRNN-
490 500 510 520 530
980 990 1000 1010 1020 1030
pF1KE1 QLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLKDCMRRLF
.::.: .. :. : . :. :. : . :: .:. .:. .
XP_011 -----KNFSTVDIQ-----KNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKE-----I
540 550 560 570 580
1040 1050 1060 1070 1080 1090
pF1KE1 YNFDKNY-KDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELKGSRH
:....: . :. . .: ::... .:. : :. :. ::.:: : . ::.:::
XP_011 VNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAIL--EKGQGRIILKASRH
590 600 610 620 630
1100 1110 1120 1130 1140 1150
pF1KE1 PCITKTFFGDD--FIPNDILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMA
:. :. :::::. . :. : . ..:::::::::: .::.:....::
XP_011 ACVE---VQDEIAFIPNDVYF-------EKDKQMFHIITGPNMGGKSTYIRQTGVIVLMA
640 650 660 670 680
1160 1170 1180 1190 1200 1210
pF1KE1 QMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDE
:.::.:: : ... .: ...:.::.: ..: :::..:. :::::: :: ::...::
XP_011 QIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDE
690 700 710 720 730 740
1220 1230 1240 1250 1260 1270
pF1KE1 LGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVENE
:::::.:.:: ..: :. . .: : .:.::.: :. .: .: :.. ..
XP_011 LGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALT---
750 760 770 780 790 800
1280 1290 1300 1310 1320 1330
pF1KE1 CEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQSLRLFR
..::.:.::. ::.: .:.:...:.:::.:..::. ...:: :.:.
XP_011 ----TEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEEFQYIGESQG
810 820 830 840 850 860
1340 1350 1360
pF1KE1 EVCLASERSTVDAEAVHKLLTLIKEL
XP_011 YDIMEPAAKKCYLERENLRVTEPKDQCLILLTWKRKLRGGKRSACSRPERQNQGSATPSA
870 880 890 900 910 920
>>NP_000242 (OMIM: 120435,158320,276300,609309) DNA mism (934 aa)
initn: 678 init1: 428 opt: 590 Z-score: 470.0 bits: 98.8 E(85289): 1.9e-19
Smith-Waterman score: 835; 26.8% identity (56.9% similar) in 921 aa overlap (430-1325:40-853)
400 410 420 430 440 450
pF1KE1 EDFLNSCTPGMRKWWQIKSQNFDLVICYKVGKFYELYHMDALIGVSEL----GLVFMKGN
: :: . :::... :. :.. . :
NP_000 QLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKTQGVIKYMGP
10 20 30 40 50 60
460 470 480 490 500 510
pF1KE1 WAHSGFPEIAFGRYS-DSLVQKGYKVARVEQTETPEMMEARCRKMAHISKYDRVVRREIC
. ... ....... .:.: : ..: ..:. . : . :: . .
NP_000 AGAKNLQSVVLSKMNFESFV-KDLLLVRQYRVEV-----YKNRAGNKASKENDWY---LA
70 80 90 100 110 120
520 530 540 550 560 570
pF1KE1 RIITKG--TQTYSVLEGDPSENYSKYLLSLKEKEEDSSGHTRAYGVCFVDTSLGKFFIGQ
. : .: ..: :. . . : ....: . :.. : :: .::. :. . .
NP_000 YKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQ---RQVGVGYVDSIQRKLGLCE
130 140 150 160 170
580 590 600 610 620 630
pF1KE1 FSDDRHCSRFRTLVAHYPPVQVLFEKGNLSKETKTILKSSLSCSLQEGLIPGSQFWDASK
: :. . : ...:. . : . .. :. . . ..: .:.: : .. :.
NP_000 FPDNDQFSNLEALLIQIGPKECVLPGGETAGDM-----GKLRQIIQRGGILITERKKADF
180 190 200 210 220 230
640 650 660 670 680 690
pF1KE1 TLRTLLEEEYFREKLSDGIGVMLPQVLKGMTSESDSIGLTPGEKSELALSALGGCVFYLK
. . . .. : ..::: .:. . .. : ....:.:.:.. . .:
NP_000 STKDIYQD--------------LNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFL-
240 250 260 270
700 710 720 730 740 750
pF1KE1 KCLIDQELLSM-ANFEEYIPLDSDTVSTTRSGAIFTKAYQRMVLDAVTLNNLEIFLNGTN
:::: .:: .. : :. : : :: ... :..: .:.
NP_000 ------ELLSDDSNFGQFELTTFD----------FS---QYMKLDIAAVRALNLF-QGSV
280 290 300 310
760 770 780 790 800
pF1KE1 GSTEGT--LLERVDTCHTPFGKRLLKQWLCAPLCNHYAINDRLDAIEDLMVVPDKISEVV
.: :. : .. :.:: :.::..::. :: .. :..::. .: . : .. ...
NP_000 EDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAF-VEDAELRQTL
320 330 340 350 360 370
810 820 830 840 850
pF1KE1 E--LLKKLPDLERLLSKIHNVGSPLKS--------QNHPDS-RAIMYEETTYSKKKIIDF
. ::...:::.:: .:.. .. :.. .. :. .:. .: ..: . :
NP_000 QEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVF
380 390 400 410 420 430
860 870 880 890 900 910
pF1KE1 LSALEGFKV-MCKIIGIMEEVADGFKSKILKQVISLQTKNPEGRFPDLTVELNRWDTAFD
.. : .. . :. ..: . : . :: . . . :.:. :: . :
NP_000 VTPLTDLRSDFSKFQEMIETTLD------MDQVENHEFLVKPSFDPNLS-ELR--EIMND
440 450 460 470 480
920 930 940 950 960 970
pF1KE1 HEKARKTGLITPKAGFDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRY
:: .. ::. :. : : . .:. . .. . : :. :. . ::
NP_000 LEKKMQSTLIS--AARDLGLDPG-KQIKLDSSAQFGYYF----RVTCKE---EKVLRNN-
490 500 510 520 530
980 990 1000 1010 1020 1030
pF1KE1 QLEIPENFTTRNLPEEYELKSTKKGCKRYWTKTIEKKLANLINAEERRDVSLKDCMRRLF
.::.: .. :. : . :. :. : . :: .:. .:. .
NP_000 -----KNFSTVDIQ-----KNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKE-----I
540 550 560 570 580
1040 1050 1060 1070 1080 1090
pF1KE1 YNFDKNY-KDWQSAVECIAVLDVLLCLANYSRGGDGPMCRPVILLPEDTPPFLELKGSRH
:....: . :. . .: ::... .:. : :. :. ::.:: : . ::.:::
NP_000 VNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAIL--EKGQGRIILKASRH
590 600 610 620 630
1100 1110 1120 1130 1140 1150
pF1KE1 PCITKTFFGDD--FIPNDILIGCEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLAVMA
:. :. :::::. . :. : . ..:::::::::: .::.:....::
NP_000 ACVE---VQDEIAFIPNDVYF-------EKDKQMFHIITGPNMGGKSTYIRQTGVIVLMA
640 650 660 670 680
1160 1170 1180 1190 1200 1210
pF1KE1 QMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVLVDE
:.::.:: : ... .: ...:.::.: ..: :::..:. :::::: :: ::...::
NP_000 QIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDE
690 700 710 720 730 740
1220 1230 1240 1250 1260 1270
pF1KE1 LGRGTATFDGTAIANAVVKELAETIKCRTLFSTHYHSLVEDYSQNVAVRLGHMACMVENE
:::::.:.:: ..: :. . .: : .:.::.: :. .: .: :.. ..
NP_000 LGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALT---
750 760 770 780 790 800
1280 1290 1300 1310 1320 1330
pF1KE1 CEDPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQKGHRKAREFEKMNQSLRLFR
..::.:.::. ::.: .:.:...:.:::.:..::. ...:: :.:.
NP_000 ----TEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEEFQYIGESQG
810 820 830 840 850 860
1340 1350 1360
pF1KE1 EVCLASERSTVDAEAVHKLLTLIKEL
NP_000 YDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMSEENITIKLKQLKAEVIAKNNSF
870 880 890 900 910 920
1360 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:29:50 2016 done: Mon Nov 7 02:29:52 2016
Total Scan time: 13.580 Total Display time: 0.470
Function used was FASTA [36.3.4 Apr, 2011]