Result of FASTA (omim) for
pFN21AA0054
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0054, 1942 aa
1>>>pF1KA0054 1942 - 1942 aa - 1942 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.1806+/-0.000502; mu= -6.6964+/- 0.031
mean_var=459.1821+/-96.596, 0's: 0 Z-trim(120.0): 83 B-trim: 333 in 2/57
Lambda= 0.059852
statistics sampled from 34560 (34647) to 34560 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.406), width: 16
Scan time: 20.810
The best scores are: opt bits E(85289)
NP_055692 (OMIM: 606699) probable helicase with zi (1942) 13193 1155.8 0
NP_001317376 (OMIM: 606699) probable helicase with (1943) 13181 1154.8 0
XP_016880966 (OMIM: 606699) PREDICTED: probable he (1707) 11618 1019.7 0
XP_016880967 (OMIM: 606699) PREDICTED: probable he (1551) 10564 928.7 0
XP_005257945 (OMIM: 606699) PREDICTED: probable he (1969) 10050 884.4 0
XP_006722279 (OMIM: 606699) PREDICTED: probable he (1578) 10038 883.3 0
XP_006722278 (OMIM: 606699) PREDICTED: probable he (1735) 10038 883.3 0
XP_011523846 (OMIM: 606699) PREDICTED: probable he (1970) 10038 883.4 0
XP_006722277 (OMIM: 606699) PREDICTED: probable he (1970) 10038 883.4 0
NP_001032412 (OMIM: 611265) helicase with zinc fin (2649) 1101 111.8 9.8e-23
NP_208384 (OMIM: 611265) helicase with zinc finger (2080) 769 83.0 3.5e-14
XP_016856808 (OMIM: 610742) PREDICTED: putative he ( 936) 352 46.7 0.0014
>>NP_055692 (OMIM: 606699) probable helicase with zinc f (1942 aa)
initn: 13193 init1: 13193 opt: 13193 Z-score: 6173.9 bits: 1155.8 E(85289): 0
Smith-Waterman score: 13193; 100.0% identity (100.0% similar) in 1942 aa overlap (1-1942:1-1942)
10 20 30 40 50 60
pF1KA0 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 KQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 CEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LPPVLIIGPYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LPPVLIIGPYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 QARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 LDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 HVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHGI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 TFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQNDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQNDH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 FQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVYG
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 GNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPVT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 IGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPES
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 RPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTLL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 NQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHRP
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA0 QSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALDRIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALDRIH
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA0 GSVALETLRQQQARFQQWSEHHAFLSQGSVPYPHHHHPHLQHLPQPPLGLHQPPVRADWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GSVALETLRQQQARFQQWSEHHAFLSQGSVPYPHHHHPHLQHLPQPPLGLHQPPVRADWK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA0 LTSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LTSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVPS
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA0 PPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAPD
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA0 GAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSSS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA0 SLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFSS
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA0 PESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSVL
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KA0 QHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDPL
1870 1880 1890 1900 1910 1920
1930 1940
pF1KA0 SLFQELSLGSSSGSNGFYSYFK
::::::::::::::::::::::
NP_055 SLFQELSLGSSSGSNGFYSYFK
1930 1940
>>NP_001317376 (OMIM: 606699) probable helicase with zin (1943 aa)
initn: 8663 init1: 8663 opt: 13181 Z-score: 6168.3 bits: 1154.8 E(85289): 0
Smith-Waterman score: 13181; 99.9% identity (99.9% similar) in 1943 aa overlap (1-1942:1-1943)
10 20 30 40 50 60
pF1KA0 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 KVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 KQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 CEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQ
610 620 630 640 650 660
670 680 690 700 710
pF1KA0 LPPVLIIGPYGTGKTFTLAQAVKHILQQQET-RILICTHSNSAADLYIKDYLHPYVEAGN
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_001 LPPVLIIGPYGTGKTFTLAQAVKHILQQQETSRILICTHSNSAADLYIKDYLHPYVEAGN
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 PQARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLC
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 QLDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERN
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 LHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYP
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 LTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQ
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA0 VFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDS
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA0 TEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHG
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA0 ITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQND
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA0 HFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVY
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA0 GGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPV
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA0 TIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPE
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA0 SRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTL
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KA0 LNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHR
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KA0 PQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALDRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALDRI
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KA0 HGSVALETLRQQQARFQQWSEHHAFLSQGSVPYPHHHHPHLQHLPQPPLGLHQPPVRADW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGSVALETLRQQQARFQQWSEHHAFLSQGSVPYPHHHHPHLQHLPQPPLGLHQPPVRADW
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KA0 KLTSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLTSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVP
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KA0 SPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAP
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KA0 DGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSS
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KA0 SSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFS
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KA0 SPESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSV
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900 1910
pF1KA0 LQHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDP
1870 1880 1890 1900 1910 1920
1920 1930 1940
pF1KA0 LSLFQELSLGSSSGSNGFYSYFK
:::::::::::::::::::::::
NP_001 LSLFQELSLGSSSGSNGFYSYFK
1930 1940
>>XP_016880966 (OMIM: 606699) PREDICTED: probable helica (1707 aa)
initn: 11618 init1: 11618 opt: 11618 Z-score: 5439.6 bits: 1019.7 E(85289): 0
Smith-Waterman score: 11618; 99.9% identity (100.0% similar) in 1707 aa overlap (236-1942:1-1707)
210 220 230 240 250 260
pF1KA0 EELAEWQKRYASRLIKLKQQNENKQLSGSYMETLIEKWMNSLSPEKVLSECIEGVKVEHN
::::::::::::::::::::::::::::::
XP_016 METLIEKWMNSLSPEKVLSECIEGVKVEHN
10 20 30
270 280 290 300 310 320
pF1KA0 PDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLYDAHRPHFSIIAISAGDSTTQVSQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLYDAHRPHFSIIAISAGDSTTQVSQEV
40 50 60 70 80 90
330 340 350 360 370 380
pF1KA0 PENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGTFRQTIVFDFGLEPVLMQRVMIDAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGTFRQTIVFDFGLEPVLMQRVMIDAAS
100 110 120 130 140 150
390 400 410 420 430 440
pF1KA0 TEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNETTDLEKSLLIRYQIPLSADQLFTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNETTDLEKSLLIRYQIPLSADQLFTQS
160 170 180 190 200 210
450 460 470 480 490 500
pF1KA0 VLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNLKVQLQILASFMLTGVSGGAKYAQNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNLKVQLQILASFMLTGVSGGAKYAQNG
220 230 240 250 260 270
510 520 530 540 550 560
pF1KA0 QLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKE
280 290 300 310 320 330
570 580 590 600 610 620
pF1KA0 YIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPDISMTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPDISMTPT
340 350 360 370 380 390
630 640 650 660 670 680
pF1KA0 IPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHI
400 410 420 430 440 450
690 700 710 720 730 740
pF1KA0 LQQQETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQQQETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYC
460 470 480 490 500 510
750 760 770 780 790 800
pF1KA0 LISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETI
520 530 540 550 560 570
810 820 830 840 850 860
pF1KA0 MPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCEN
580 590 600 610 620 630
870 880 890 900 910 920
pF1KA0 YRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPLTFFTARGEDVQEKNSTAFYNNAEVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPLTFFTARGEDVQEKNSTAFYNNAEVF
640 650 660 670 680 690
930 940 950 960 970 980
pF1KA0 EVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQG
700 710 720 730 740 750
990 1000 1010 1020 1030 1040
pF1KA0 KQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLV
760 770 780 790 800 810
1050 1060 1070 1080 1090 1100
pF1KA0 AVVGDPIALCSIGRCRKFWERFIALCHENSSLHGITFEQIKAQLEALELKKTYVLNPLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVVGDPIALCSIGRCRKFWERFIALCHENSSLHGITFEQIKAQLEALELKKTYVLNPLAP
820 830 840 850 860 870
1110 1120 1130 1140 1150 1160
pF1KA0 EFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQNDHFQNDGIVQPNPSVLIGNPIRAYTPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQNDHFQNDGIVQPNPSVLIGNPIRAYTPP
880 890 900 910 920 930
1170 1180 1190 1200 1210 1220
pF1KA0 PPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVYGGNVVMSVPLPVPWTGYQGRFAVDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVYGGNVVMSVPLPVPWTGYQGRFAVDPR
940 950 960 970 980 990
1230 1240 1250 1260 1270 1280
pF1KA0 IITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPVTIGQPQNQHQEKDQHEQNRNGKSDTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPVTIGQPQNQHQEKDQHEQNRNGKSDTN
1000 1010 1020 1030 1040 1050
1290 1300 1310 1320 1330 1340
pF1KA0 NSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPESRPSVVYPSTKFPRKDNLNPRHINLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPESRPSVVYPSTKFPRKDNLNPRHINLP
1060 1070 1080 1090 1100 1110
1350 1360 1370 1380 1390 1400
pF1KA0 LPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTLLNQQQNNLPEQPNQIPPQPNQVVQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTLLNQQQNNLPEQPNQIPPQPNQVVQQQ
1120 1130 1140 1150 1160 1170
1410 1420 1430 1440 1450 1460
pF1KA0 SQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHRPQSPPAEAVIPEQQPPPMLQEGHSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHRPQSPPAEAVIPEQQPPPMLQEGHSPL
1180 1190 1200 1210 1220 1230
1470 1480 1490 1500 1510 1520
pF1KA0 RAIAQPGPILPSHLNSFIDENPSGLPIGEALDRIHGSVALETLRQQQARFQQWSEHHAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAIAQPGPILPSHLNSFIDENPSGLPIGEALDRIHGSVALETLRQQQARFQQWSEHHAFL
1240 1250 1260 1270 1280 1290
1530 1540 1550 1560 1570 1580
pF1KA0 SQGSVPYPHHHHPHLQHLPQPPLGLHQPPVRADWKLTSSAEDEVETTYSRFQDLIRELSH
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQGSAPYPHHHHPHLQHLPQPPLGLHQPPVRADWKLTSSAEDEVETTYSRFQDLIRELSH
1300 1310 1320 1330 1340 1350
1590 1600 1610 1620 1630 1640
pF1KA0 RDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVPSPPSSTDHSSHFSNFNDNSRDIEVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVPSPPSSTDHSSHFSNFNDNSRDIEVAS
1360 1370 1380 1390 1400 1410
1650 1660 1670 1680 1690 1700
pF1KA0 NPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAPDGAWTFANLQQNHLMGPGFPYGLPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAPDGAWTFANLQQNHLMGPGFPYGLPPL
1420 1430 1440 1450 1460 1470
1710 1720 1730 1740 1750 1760
pF1KA0 PHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSSSSLPSLEEYEPRGPGRPLYQRRISSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSSSSLPSLEEYEPRGPGRPLYQRRISSS
1480 1490 1500 1510 1520 1530
1770 1780 1790 1800 1810 1820
pF1KA0 SVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFSSPESWVNTTSSTPYQNIPCNGSSRTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFSSPESWVNTTSSTPYQNIPCNGSSRTA
1540 1550 1560 1570 1580 1590
1830 1840 1850 1860 1870 1880
pF1KA0 QPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSVLQHLGQFPPLMPNKQIAESANSSSPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSVLQHLGQFPPLMPNKQIAESANSSSPQ
1600 1610 1620 1630 1640 1650
1890 1900 1910 1920 1930 1940
pF1KA0 SSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDPLSLFQELSLGSSSGSNGFYSYFK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDPLSLFQELSLGSSSGSNGFYSYFK
1660 1670 1680 1690 1700
>>XP_016880967 (OMIM: 606699) PREDICTED: probable helica (1551 aa)
initn: 8658 init1: 8658 opt: 10564 Z-score: 4948.3 bits: 928.7 E(85289): 0
Smith-Waterman score: 10564; 99.9% identity (99.9% similar) in 1551 aa overlap (393-1942:1-1551)
370 380 390 400 410 420
pF1KA0 QTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNETT
::::::::::::::::::::::::::::::
XP_016 MHAKQQLVTTAKRWDSSSKTIIDFEPNETT
10 20 30
430 440 450 460 470 480
pF1KA0 DLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNLKV
40 50 60 70 80 90
490 500 510 520 530 540
pF1KA0 QLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVPKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVPKQ
100 110 120 130 140 150
550 560 570 580 590 600
pF1KA0 KLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPLCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPLCE
160 170 180 190 200 210
610 620 630 640 650 660
pF1KA0 MHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQLP
220 230 240 250 260 270
670 680 690 700 710 720
pF1KA0 PVLIIGPYGTGKTFTLAQAVKHILQQQET-RILICTHSNSAADLYIKDYLHPYVEAGNPQ
::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
XP_016 PVLIIGPYGTGKTFTLAQAVKHILQQQETSRILICTHSNSAADLYIKDYLHPYVEAGNPQ
280 290 300 310 320 330
730 740 750 760 770 780
pF1KA0 ARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQL
340 350 360 370 380 390
790 800 810 820 830 840
pF1KA0 DLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLH
400 410 420 430 440 450
850 860 870 880 890 900
pF1KA0 VSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPLT
460 470 480 490 500 510
910 920 930 940 950 960
pF1KA0 FFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVF
520 530 540 550 560 570
970 980 990 1000 1010 1020
pF1KA0 RIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTE
580 590 600 610 620 630
1030 1040 1050 1060 1070 1080
pF1KA0 DLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHGIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHGIT
640 650 660 670 680 690
1090 1100 1110 1120 1130 1140
pF1KA0 FEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQNDHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQNDHF
700 710 720 730 740 750
1150 1160 1170 1180 1190 1200
pF1KA0 QNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVYGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVYGG
760 770 780 790 800 810
1210 1220 1230 1240 1250 1260
pF1KA0 NVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPVTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPVTI
820 830 840 850 860 870
1270 1280 1290 1300 1310 1320
pF1KA0 GQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPESR
880 890 900 910 920 930
1330 1340 1350 1360 1370 1380
pF1KA0 PSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTLLN
940 950 960 970 980 990
1390 1400 1410 1420 1430 1440
pF1KA0 QQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHRPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHRPQ
1000 1010 1020 1030 1040 1050
1450 1460 1470 1480 1490 1500
pF1KA0 SPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALDRIHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALDRIHG
1060 1070 1080 1090 1100 1110
1510 1520 1530 1540 1550 1560
pF1KA0 SVALETLRQQQARFQQWSEHHAFLSQGSVPYPHHHHPHLQHLPQPPLGLHQPPVRADWKL
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_016 SVALETLRQQQARFQQWSEHHAFLSQGSAPYPHHHHPHLQHLPQPPLGLHQPPVRADWKL
1120 1130 1140 1150 1160 1170
1570 1580 1590 1600 1610 1620
pF1KA0 TSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVPSP
1180 1190 1200 1210 1220 1230
1630 1640 1650 1660 1670 1680
pF1KA0 PSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAPDG
1240 1250 1260 1270 1280 1290
1690 1700 1710 1720 1730 1740
pF1KA0 AWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSSSS
1300 1310 1320 1330 1340 1350
1750 1760 1770 1780 1790 1800
pF1KA0 LPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFSSP
1360 1370 1380 1390 1400 1410
1810 1820 1830 1840 1850 1860
pF1KA0 ESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSVLQ
1420 1430 1440 1450 1460 1470
1870 1880 1890 1900 1910 1920
pF1KA0 HLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDPLS
1480 1490 1500 1510 1520 1530
1930 1940
pF1KA0 LFQELSLGSSSGSNGFYSYFK
:::::::::::::::::::::
XP_016 LFQELSLGSSSGSNGFYSYFK
1540 1550
>>XP_005257945 (OMIM: 606699) PREDICTED: probable helica (1969 aa)
initn: 13168 init1: 10045 opt: 10050 Z-score: 4707.0 bits: 884.4 E(85289): 0
Smith-Waterman score: 13118; 98.5% identity (98.6% similar) in 1969 aa overlap (1-1942:1-1969)
10 20 30 40 50 60
pF1KA0 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
370 380 390 400 410 420
430 440 450 460 470
pF1KA0 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISK---
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_005 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISNTSG
430 440 450 460 470 480
480 490 500 510
pF1KA0 ------------------------FNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKL
::::::::::::::::::::::::::::::::::::
XP_005 ASTSRILLQDTTNVTRGFSCCSKLFNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKL
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 TETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSR
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 ECCEELNLRPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECCEELNLRPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQ
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 WDEQLDPRLNAKQKEAVLAITTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQETRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WDEQLDPRLNAKQKEAVLAITTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQETRI
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 LICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAHST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAHST
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA0 FQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALATQ
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA0 NTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAII
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 NYTSELFYEGKLMASGKQPAHKDFYPLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NYTSELFYEGKLMASGKQPAHKDFYPLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEE
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 LRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFL
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KA0 STVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIA
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KA0 LCSIGRCRKFWERFIALCHENSSLHGITFEQIKAQLEALELKKTYVLNPLAPEFIPRALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCSIGRCRKFWERFIALCHENSSLHGITFEQIKAQLEALELKKTYVLNPLAPEFIPRALR
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KA0 LQHSGSTNKQQQSPPKGKSLHHTQNDHFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQHSGSTNKQQQSPPKGKSLHHTQNDHFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPN
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220 1230
pF1KA0 LGKSPSPVQRIDPHTGTSILYVPAVYGGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGKSPSPVQRIDPHTGTSILYVPAVYGGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAM
1210 1220 1230 1240 1250 1260
1240 1250 1260 1270 1280 1290
pF1KA0 AYNMNLLQTHGRGSPIPYGLGHHPPVTIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AYNMNLLQTHGRGSPIPYGLGHHPPVTIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINK
1270 1280 1290 1300 1310 1320
1300 1310 1320 1330 1340 1350
pF1KA0 IRTPEKKPTEPKQVDLESNPQNRSPESRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRTPEKKPTEPKQVDLESNPQNRSPESRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQY
1330 1340 1350 1360 1370 1380
1360 1370 1380 1390 1400 1410
pF1KA0 AIPNRHFHPLPQLPRPPFPIPQQHTLLNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIPNRHFHPLPQLPRPPFPIPQQHTLLNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQ
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KA0 QPPPQLSPAYQAGPNNAFFNSAVAHRPQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPPPQLSPAYQAGPNNAFFNSAVAHRPQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGP
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KA0 ILPSHLNSFIDENPSGLPIGEALDRIHGSVALETLRQQQARFQQWSEHHAFLSQGSVPYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
XP_005 ILPSHLNSFIDENPSGLPIGEALDRIHGSVALETLRQQQARFQQWSEHHAFLSQGSAPYP
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KA0 HHHHPHLQHLPQPPLGLHQPPVRADWKLTSSAEDEVETTYSRFQDLIRELSHRDQSETRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HHHHPHLQHLPQPPLGLHQPPVRADWKLTSSAEDEVETTYSRFQDLIRELSHRDQSETRE
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KA0 LAEMPPPQSRLLQYRQVQSRSPPAVPSPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAEMPPPQSRLLQYRQVQSRSPPAVPSPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRL
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KA0 PPQIFNSPFSLPSEHLAPPPLKYLAPDGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPQIFNSPFSLPSEHLAPPPLKYLAPDGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNP
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KA0 FVQIQNHQHAIGQEPFHPLSSRTVSSSSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FVQIQNHQHAIGQEPFHPLSSRTVSSSSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEE
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KA0 VSTPQDSLAQCKELQDHSNQSSFNFSSPESWVNTTSSTPYQNIPCNGSSRTAQPRELIAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSTPQDSLAQCKELQDHSNQSSFNFSSPESWVNTTSSTPYQNIPCNGSSRTAQPRELIAP
1810 1820 1830 1840 1850 1860
1840 1850 1860 1870 1880 1890
pF1KA0 PKTVKPPEDQLKSENLEVSSSFNYSVLQHLGQFPPLMPNKQIAESANSSSPQSSAGGKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKTVKPPEDQLKSENLEVSSSFNYSVLQHLGQFPPLMPNKQIAESANSSSPQSSAGGKPA
1870 1880 1890 1900 1910 1920
1900 1910 1920 1930 1940
pF1KA0 MSYASALRAPPKPRPPPEQAKKSSDPLSLFQELSLGSSSGSNGFYSYFK
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSYASALRAPPKPRPPPEQAKKSSDPLSLFQELSLGSSSGSNGFYSYFK
1930 1940 1950 1960
>>XP_006722279 (OMIM: 606699) PREDICTED: probable helica (1578 aa)
initn: 9169 init1: 8658 opt: 10038 Z-score: 4702.7 bits: 883.3 E(85289): 0
Smith-Waterman score: 10494; 98.1% identity (98.2% similar) in 1578 aa overlap (393-1942:1-1578)
370 380 390 400 410 420
pF1KA0 QTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNETT
::::::::::::::::::::::::::::::
XP_006 MHAKQQLVTTAKRWDSSSKTIIDFEPNETT
10 20 30
430 440 450 460 470
pF1KA0 DLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISK-----
::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_006 DLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISNTSGAS
40 50 60 70 80 90
480 490 500 510
pF1KA0 ----------------------FNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTE
::::::::::::::::::::::::::::::::::::::
XP_006 TSRILLQDTTNVTRGFSCCSKLFNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTE
100 110 120 130 140 150
520 530 540 550 560 570
pF1KA0 TLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSREC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSREC
160 170 180 190 200 210
580 590 600 610 620 630
pF1KA0 CEELNLRPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CEELNLRPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWD
220 230 240 250 260 270
640 650 660 670 680 690
pF1KA0 EQLDPRLNAKQKEAVLAITTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQET-RIL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_006 EQLDPRLNAKQKEAVLAITTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQETSRIL
280 290 300 310 320 330
700 710 720 730 740 750
pF1KA0 ICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTF
340 350 360 370 380 390
760 770 780 790 800 810
pF1KA0 QMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALATQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALATQN
400 410 420 430 440 450
820 830 840 850 860 870
pF1KA0 TRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIIN
460 470 480 490 500 510
880 890 900 910 920 930
pF1KA0 YTSELFYEGKLMASGKQPAHKDFYPLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YTSELFYEGKLMASGKQPAHKDFYPLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEEL
520 530 540 550 560 570
940 950 960 970 980 990
pF1KA0 RRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLS
580 590 600 610 620 630
1000 1010 1020 1030 1040 1050
pF1KA0 TVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIAL
640 650 660 670 680 690
1060 1070 1080 1090 1100 1110
pF1KA0 CSIGRCRKFWERFIALCHENSSLHGITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CSIGRCRKFWERFIALCHENSSLHGITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRL
700 710 720 730 740 750
1120 1130 1140 1150 1160 1170
pF1KA0 QHSGSTNKQQQSPPKGKSLHHTQNDHFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QHSGSTNKQQQSPPKGKSLHHTQNDHFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNL
760 770 780 790 800 810
1180 1190 1200 1210 1220 1230
pF1KA0 GKSPSPVQRIDPHTGTSILYVPAVYGGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKSPSPVQRIDPHTGTSILYVPAVYGGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMA
820 830 840 850 860 870
1240 1250 1260 1270 1280 1290
pF1KA0 YNMNLLQTHGRGSPIPYGLGHHPPVTIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YNMNLLQTHGRGSPIPYGLGHHPPVTIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKI
880 890 900 910 920 930
1300 1310 1320 1330 1340 1350
pF1KA0 RTPEKKPTEPKQVDLESNPQNRSPESRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTPEKKPTEPKQVDLESNPQNRSPESRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYA
940 950 960 970 980 990
1360 1370 1380 1390 1400 1410
pF1KA0 IPNRHFHPLPQLPRPPFPIPQQHTLLNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IPNRHFHPLPQLPRPPFPIPQQHTLLNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQ
1000 1010 1020 1030 1040 1050
1420 1430 1440 1450 1460 1470
pF1KA0 PPPQLSPAYQAGPNNAFFNSAVAHRPQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPPQLSPAYQAGPNNAFFNSAVAHRPQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPI
1060 1070 1080 1090 1100 1110
1480 1490 1500 1510 1520 1530
pF1KA0 LPSHLNSFIDENPSGLPIGEALDRIHGSVALETLRQQQARFQQWSEHHAFLSQGSVPYPH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_006 LPSHLNSFIDENPSGLPIGEALDRIHGSVALETLRQQQARFQQWSEHHAFLSQGSAPYPH
1120 1130 1140 1150 1160 1170
1540 1550 1560 1570 1580 1590
pF1KA0 HHHPHLQHLPQPPLGLHQPPVRADWKLTSSAEDEVETTYSRFQDLIRELSHRDQSETREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HHHPHLQHLPQPPLGLHQPPVRADWKLTSSAEDEVETTYSRFQDLIRELSHRDQSETREL
1180 1190 1200 1210 1220 1230
1600 1610 1620 1630 1640 1650
pF1KA0 AEMPPPQSRLLQYRQVQSRSPPAVPSPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEMPPPQSRLLQYRQVQSRSPPAVPSPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLP
1240 1250 1260 1270 1280 1290
1660 1670 1680 1690 1700 1710
pF1KA0 PQIFNSPFSLPSEHLAPPPLKYLAPDGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQIFNSPFSLPSEHLAPPPLKYLAPDGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPF
1300 1310 1320 1330 1340 1350
1720 1730 1740 1750 1760 1770
pF1KA0 VQIQNHQHAIGQEPFHPLSSRTVSSSSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VQIQNHQHAIGQEPFHPLSSRTVSSSSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEV
1360 1370 1380 1390 1400 1410
1780 1790 1800 1810 1820 1830
pF1KA0 STPQDSLAQCKELQDHSNQSSFNFSSPESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STPQDSLAQCKELQDHSNQSSFNFSSPESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPP
1420 1430 1440 1450 1460 1470
1840 1850 1860 1870 1880 1890
pF1KA0 KTVKPPEDQLKSENLEVSSSFNYSVLQHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KTVKPPEDQLKSENLEVSSSFNYSVLQHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAM
1480 1490 1500 1510 1520 1530
1900 1910 1920 1930 1940
pF1KA0 SYASALRAPPKPRPPPEQAKKSSDPLSLFQELSLGSSSGSNGFYSYFK
::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SYASALRAPPKPRPPPEQAKKSSDPLSLFQELSLGSSSGSNGFYSYFK
1540 1550 1560 1570
>>XP_006722278 (OMIM: 606699) PREDICTED: probable helica (1735 aa)
initn: 10211 init1: 8658 opt: 10038 Z-score: 4702.2 bits: 883.3 E(85289): 0
Smith-Waterman score: 11536; 98.3% identity (98.4% similar) in 1735 aa overlap (236-1942:1-1735)
210 220 230 240 250 260
pF1KA0 EELAEWQKRYASRLIKLKQQNENKQLSGSYMETLIEKWMNSLSPEKVLSECIEGVKVEHN
::::::::::::::::::::::::::::::
XP_006 METLIEKWMNSLSPEKVLSECIEGVKVEHN
10 20 30
270 280 290 300 310 320
pF1KA0 PDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLYDAHRPHFSIIAISAGDSTTQVSQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLYDAHRPHFSIIAISAGDSTTQVSQEV
40 50 60 70 80 90
330 340 350 360 370 380
pF1KA0 PENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGTFRQTIVFDFGLEPVLMQRVMIDAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGTFRQTIVFDFGLEPVLMQRVMIDAAS
100 110 120 130 140 150
390 400 410 420 430 440
pF1KA0 TEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNETTDLEKSLLIRYQIPLSADQLFTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNETTDLEKSLLIRYQIPLSADQLFTQS
160 170 180 190 200 210
450 460 470
pF1KA0 VLDKSLTKSNYQSRLHDLLYIEEIAQYKEISK---------------------------F
:::::::::::::::::::::::::::::::. :
XP_006 VLDKSLTKSNYQSRLHDLLYIEEIAQYKEISNTSGASTSRILLQDTTNVTRGFSCCSKLF
220 230 240 250 260 270
480 490 500 510 520 530
pF1KA0 NLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLP
280 290 300 310 320 330
540 550 560 570 580 590
pF1KA0 VPKQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPKQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRL
340 350 360 370 380 390
600 610 620 630 640 650
pF1KA0 PLCEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLCEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLA
400 410 420 430 440 450
660 670 680 690 700 710
pF1KA0 IQLPPVLIIGPYGTGKTFTLAQAVKHILQQQET-RILICTHSNSAADLYIKDYLHPYVEA
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_006 IQLPPVLIIGPYGTGKTFTLAQAVKHILQQQETSRILICTHSNSAADLYIKDYLHPYVEA
460 470 480 490 500 510
720 730 740 750 760 770
pF1KA0 GNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQY
520 530 540 550 560 570
780 790 800 810 820 830
pF1KA0 LCQLDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LCQLDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARE
580 590 600 610 620 630
840 850 860 870 880 890
pF1KA0 RNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDF
640 650 660 670 680 690
900 910 920 930 940 950
pF1KA0 YPLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YPLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYA
700 710 720 730 740 750
960 970 980 990 1000 1010
pF1KA0 DQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLE
760 770 780 790 800 810
1020 1030 1040 1050 1060 1070
pF1KA0 DSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL
820 830 840 850 860 870
1080 1090 1100 1110 1120 1130
pF1KA0 HGITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HGITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQ
880 890 900 910 920 930
1140 1150 1160 1170 1180 1190
pF1KA0 NDHFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NDHFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPA
940 950 960 970 980 990
1200 1210 1220 1230 1240 1250
pF1KA0 VYGGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VYGGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHP
1000 1010 1020 1030 1040 1050
1260 1270 1280 1290 1300 1310
pF1KA0 PVTIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVTIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRS
1060 1070 1080 1090 1100 1110
1320 1330 1340 1350 1360 1370
pF1KA0 PESRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PESRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQH
1120 1130 1140 1150 1160 1170
1380 1390 1400 1410 1420 1430
pF1KA0 TLLNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLLNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVA
1180 1190 1200 1210 1220 1230
1440 1450 1460 1470 1480 1490
pF1KA0 HRPQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HRPQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALD
1240 1250 1260 1270 1280 1290
1500 1510 1520 1530 1540 1550
pF1KA0 RIHGSVALETLRQQQARFQQWSEHHAFLSQGSVPYPHHHHPHLQHLPQPPLGLHQPPVRA
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_006 RIHGSVALETLRQQQARFQQWSEHHAFLSQGSAPYPHHHHPHLQHLPQPPLGLHQPPVRA
1300 1310 1320 1330 1340 1350
1560 1570 1580 1590 1600 1610
pF1KA0 DWKLTSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DWKLTSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPA
1360 1370 1380 1390 1400 1410
1620 1630 1640 1650 1660 1670
pF1KA0 VPSPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPSPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYL
1420 1430 1440 1450 1460 1470
1680 1690 1700 1710 1720 1730
pF1KA0 APDGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APDGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTV
1480 1490 1500 1510 1520 1530
1740 1750 1760 1770 1780 1790
pF1KA0 SSSSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSSSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFN
1540 1550 1560 1570 1580 1590
1800 1810 1820 1830 1840 1850
pF1KA0 FSSPESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSSPESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNY
1600 1610 1620 1630 1640 1650
1860 1870 1880 1890 1900 1910
pF1KA0 SVLQHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVLQHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSS
1660 1670 1680 1690 1700 1710
1920 1930 1940
pF1KA0 DPLSLFQELSLGSSSGSNGFYSYFK
:::::::::::::::::::::::::
XP_006 DPLSLFQELSLGSSSGSNGFYSYFK
1720 1730
>>XP_011523846 (OMIM: 606699) PREDICTED: probable helica (1970 aa)
initn: 11781 init1: 8658 opt: 10038 Z-score: 4701.4 bits: 883.4 E(85289): 0
Smith-Waterman score: 13106; 98.5% identity (98.6% similar) in 1970 aa overlap (1-1942:1-1970)
10 20 30 40 50 60
pF1KA0 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
370 380 390 400 410 420
430 440 450 460 470
pF1KA0 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISK---
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_011 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISNTSG
430 440 450 460 470 480
480 490 500 510
pF1KA0 ------------------------FNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKL
::::::::::::::::::::::::::::::::::::
XP_011 ASTSRILLQDTTNVTRGFSCCSKLFNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKL
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 TETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSR
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 ECCEELNLRPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECCEELNLRPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQ
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 WDEQLDPRLNAKQKEAVLAITTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQET-R
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_011 WDEQLDPRLNAKQKEAVLAITTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQETSR
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 ILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAHS
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA0 TFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALAT
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA0 QNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAI
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 INYTSELFYEGKLMASGKQPAHKDFYPLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INYTSELFYEGKLMASGKQPAHKDFYPLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVE
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 ELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLF
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KA0 LSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPI
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KA0 ALCSIGRCRKFWERFIALCHENSSLHGITFEQIKAQLEALELKKTYVLNPLAPEFIPRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALCSIGRCRKFWERFIALCHENSSLHGITFEQIKAQLEALELKKTYVLNPLAPEFIPRAL
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KA0 RLQHSGSTNKQQQSPPKGKSLHHTQNDHFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLQHSGSTNKQQQSPPKGKSLHHTQNDHFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHP
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220 1230
pF1KA0 NLGKSPSPVQRIDPHTGTSILYVPAVYGGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLGKSPSPVQRIDPHTGTSILYVPAVYGGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAA
1210 1220 1230 1240 1250 1260
1240 1250 1260 1270 1280 1290
pF1KA0 MAYNMNLLQTHGRGSPIPYGLGHHPPVTIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAYNMNLLQTHGRGSPIPYGLGHHPPVTIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEIN
1270 1280 1290 1300 1310 1320
1300 1310 1320 1330 1340 1350
pF1KA0 KIRTPEKKPTEPKQVDLESNPQNRSPESRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIRTPEKKPTEPKQVDLESNPQNRSPESRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQ
1330 1340 1350 1360 1370 1380
1360 1370 1380 1390 1400 1410
pF1KA0 YAIPNRHFHPLPQLPRPPFPIPQQHTLLNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YAIPNRHFHPLPQLPRPPFPIPQQHTLLNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQP
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KA0 QQPPPQLSPAYQAGPNNAFFNSAVAHRPQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQPPPQLSPAYQAGPNNAFFNSAVAHRPQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPG
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KA0 PILPSHLNSFIDENPSGLPIGEALDRIHGSVALETLRQQQARFQQWSEHHAFLSQGSVPY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
XP_011 PILPSHLNSFIDENPSGLPIGEALDRIHGSVALETLRQQQARFQQWSEHHAFLSQGSAPY
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KA0 PHHHHPHLQHLPQPPLGLHQPPVRADWKLTSSAEDEVETTYSRFQDLIRELSHRDQSETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHHHHPHLQHLPQPPLGLHQPPVRADWKLTSSAEDEVETTYSRFQDLIRELSHRDQSETR
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KA0 ELAEMPPPQSRLLQYRQVQSRSPPAVPSPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELAEMPPPQSRLLQYRQVQSRSPPAVPSPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQR
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KA0 LPPQIFNSPFSLPSEHLAPPPLKYLAPDGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPQIFNSPFSLPSEHLAPPPLKYLAPDGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQN
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KA0 PFVQIQNHQHAIGQEPFHPLSSRTVSSSSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFVQIQNHQHAIGQEPFHPLSSRTVSSSSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSE
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KA0 EVSTPQDSLAQCKELQDHSNQSSFNFSSPESWVNTTSSTPYQNIPCNGSSRTAQPRELIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVSTPQDSLAQCKELQDHSNQSSFNFSSPESWVNTTSSTPYQNIPCNGSSRTAQPRELIA
1810 1820 1830 1840 1850 1860
1840 1850 1860 1870 1880 1890
pF1KA0 PPKTVKPPEDQLKSENLEVSSSFNYSVLQHLGQFPPLMPNKQIAESANSSSPQSSAGGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPKTVKPPEDQLKSENLEVSSSFNYSVLQHLGQFPPLMPNKQIAESANSSSPQSSAGGKP
1870 1880 1890 1900 1910 1920
1900 1910 1920 1930 1940
pF1KA0 AMSYASALRAPPKPRPPPEQAKKSSDPLSLFQELSLGSSSGSNGFYSYFK
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMSYASALRAPPKPRPPPEQAKKSSDPLSLFQELSLGSSSGSNGFYSYFK
1930 1940 1950 1960 1970
>>XP_006722277 (OMIM: 606699) PREDICTED: probable helica (1970 aa)
initn: 11781 init1: 8658 opt: 10038 Z-score: 4701.4 bits: 883.4 E(85289): 0
Smith-Waterman score: 13106; 98.5% identity (98.6% similar) in 1970 aa overlap (1-1942:1-1970)
10 20 30 40 50 60
pF1KA0 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
370 380 390 400 410 420
430 440 450 460 470
pF1KA0 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISK---
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_006 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISNTSG
430 440 450 460 470 480
480 490 500 510
pF1KA0 ------------------------FNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKL
::::::::::::::::::::::::::::::::::::
XP_006 ASTSRILLQDTTNVTRGFSCCSKLFNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKL
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 TETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSR
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 ECCEELNLRPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ECCEELNLRPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQ
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 WDEQLDPRLNAKQKEAVLAITTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQET-R
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_006 WDEQLDPRLNAKQKEAVLAITTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQETSR
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 ILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAHS
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA0 TFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALAT
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA0 QNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAI
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 INYTSELFYEGKLMASGKQPAHKDFYPLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 INYTSELFYEGKLMASGKQPAHKDFYPLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVE
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 ELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLF
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KA0 LSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPI
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KA0 ALCSIGRCRKFWERFIALCHENSSLHGITFEQIKAQLEALELKKTYVLNPLAPEFIPRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALCSIGRCRKFWERFIALCHENSSLHGITFEQIKAQLEALELKKTYVLNPLAPEFIPRAL
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KA0 RLQHSGSTNKQQQSPPKGKSLHHTQNDHFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLQHSGSTNKQQQSPPKGKSLHHTQNDHFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHP
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220 1230
pF1KA0 NLGKSPSPVQRIDPHTGTSILYVPAVYGGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLGKSPSPVQRIDPHTGTSILYVPAVYGGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAA
1210 1220 1230 1240 1250 1260
1240 1250 1260 1270 1280 1290
pF1KA0 MAYNMNLLQTHGRGSPIPYGLGHHPPVTIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAYNMNLLQTHGRGSPIPYGLGHHPPVTIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEIN
1270 1280 1290 1300 1310 1320
1300 1310 1320 1330 1340 1350
pF1KA0 KIRTPEKKPTEPKQVDLESNPQNRSPESRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KIRTPEKKPTEPKQVDLESNPQNRSPESRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQ
1330 1340 1350 1360 1370 1380
1360 1370 1380 1390 1400 1410
pF1KA0 YAIPNRHFHPLPQLPRPPFPIPQQHTLLNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YAIPNRHFHPLPQLPRPPFPIPQQHTLLNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQP
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KA0 QQPPPQLSPAYQAGPNNAFFNSAVAHRPQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQPPPQLSPAYQAGPNNAFFNSAVAHRPQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPG
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KA0 PILPSHLNSFIDENPSGLPIGEALDRIHGSVALETLRQQQARFQQWSEHHAFLSQGSVPY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
XP_006 PILPSHLNSFIDENPSGLPIGEALDRIHGSVALETLRQQQARFQQWSEHHAFLSQGSAPY
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KA0 PHHHHPHLQHLPQPPLGLHQPPVRADWKLTSSAEDEVETTYSRFQDLIRELSHRDQSETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PHHHHPHLQHLPQPPLGLHQPPVRADWKLTSSAEDEVETTYSRFQDLIRELSHRDQSETR
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KA0 ELAEMPPPQSRLLQYRQVQSRSPPAVPSPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELAEMPPPQSRLLQYRQVQSRSPPAVPSPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQR
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KA0 LPPQIFNSPFSLPSEHLAPPPLKYLAPDGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPPQIFNSPFSLPSEHLAPPPLKYLAPDGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQN
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KA0 PFVQIQNHQHAIGQEPFHPLSSRTVSSSSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PFVQIQNHQHAIGQEPFHPLSSRTVSSSSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSE
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KA0 EVSTPQDSLAQCKELQDHSNQSSFNFSSPESWVNTTSSTPYQNIPCNGSSRTAQPRELIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVSTPQDSLAQCKELQDHSNQSSFNFSSPESWVNTTSSTPYQNIPCNGSSRTAQPRELIA
1810 1820 1830 1840 1850 1860
1840 1850 1860 1870 1880 1890
pF1KA0 PPKTVKPPEDQLKSENLEVSSSFNYSVLQHLGQFPPLMPNKQIAESANSSSPQSSAGGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPKTVKPPEDQLKSENLEVSSSFNYSVLQHLGQFPPLMPNKQIAESANSSSPQSSAGGKP
1870 1880 1890 1900 1910 1920
1900 1910 1920 1930 1940
pF1KA0 AMSYASALRAPPKPRPPPEQAKKSSDPLSLFQELSLGSSSGSNGFYSYFK
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AMSYASALRAPPKPRPPPEQAKKSSDPLSLFQELSLGSSSGSNGFYSYFK
1930 1940 1950 1960 1970
>>NP_001032412 (OMIM: 611265) helicase with zinc finger (2649 aa)
initn: 1199 init1: 406 opt: 1101 Z-score: 529.1 bits: 111.8 E(85289): 9.8e-23
Smith-Waterman score: 1683; 33.8% identity (61.8% similar) in 940 aa overlap (166-1086:76-952)
140 150 160 170 180 190
pF1KA0 KTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEEYTLCKRFLEQGICRY
:. : :: :.. .. :: . .:.:
NP_001 LVTCHSQEAFENHCASSEHAQMVAFDQALPWEHRSPPPGLS---KFELCPK---PDLCEY
50 60 70 80 90
200 210 220 230 240 250
pF1KA0 GAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLIEKWMNSLSPEKVLSE
: ::.::: .:: :: .: .. ..:. : .. :.: :. ... : : ::.:
NP_001 GDACTKAHSAQELQEWVRR--TQAVELRGQAAWQDGLVPYQERLLAEYQRSSSEVLVLAE
100 110 120 130 140 150
260 270 280 290 300 310
pF1KA0 CIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLYDAHRPHFSIIAISAG
..::.: : : .. .:.. .::::. . : .:::: . ::..: .
NP_001 TLDGVRVTCNQPLMYQAQERKTQYSWTFAVHSEEP--LLHVALLKQEPGADFSLVAPGLP
160 170 180 190 200 210
320 330 340 350 360 370
pF1KA0 DSTTQVSQE---VPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGTFRQTIVFDFGLE
. . : :: . . ..::. .. ::::.: .::::: .
NP_001 PGRLYARGERFRVPSSTAD---------------FQVGVRVQAASFGTFEQWVVFDFGRR
220 230 240 250 260
380 390 400 410 420 430
pF1KA0 PVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPN-ETTDLEKSLLIR
:::.:.. .. .. . . .:: .... .. :. : : . .:. .
NP_001 PVLLQKLGLQLGQGRRPGPCRNLALGHPEEMERWHTGNRHVV---PGVERTAEQTALMAK
270 280 290 300 310
440 450 460 470 480 490
pF1KA0 YQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNLKVQLQILASFM
:. : : .. .:: . .. .::..:.:..:: :: :: . ..:..:. :. . ....
NP_001 YKGPALALEFNRSSVASGPISPTNYRQRMHQFLYEEEAAQQQLVAKLTLRGQVFLKTALQ
320 330 340 350 360 370
500 510 520 530 540 550
pF1KA0 LTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTK
... .: : :... . .: :: : :. :... . ::: .
NP_001 TPALN--MLFAPPGALYAEVPVPSSLMPDTDQGFLLGRAVSTALVAPVP--------APD
380 390 400 410 420
560 570 580 590 600
pF1KA0 EKVYEATIEEK--TKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPLCEMHYALDR
. :.:. .:.. ... ..: : .:: :.:.:. .:.:::.. . . : :.:
NP_001 NTVFEVRLERRASSEQALWLLLPARCCLALGLQPEARLVLEVQFQIDPMTFRLWHQAVDT
430 440 450 460 470 480
610 620 630 640 650 660
pF1KA0 IKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITT--PL-AIQLPPVLI
. .. .. ::. : ..: : :. : : ::. :: :. : . ..::.::
NP_001 LPEEQLVVPDLP-TCALP----RPWSVPPLRRGNRKQELAVALIAGWGPGDGRRVPPLLI
490 500 510 520 530 540
670 680 690 700 710 720
pF1KA0 IGPYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLR
::.:::::.:::.: ..... ::..:::::.:::::.::..:.: .: .:.:.: :::
NP_001 YGPFGTGKTYTLAMASLEVIRRPETKVLICTHTNSAADIYIREYFHSHVSGGHPEATPLR
550 560 570 580 590 600
730 740 750 760 770 780
pF1KA0 VYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPG
:.. .: .. . ::. ::: ... ...:. : . .. .:::::.: ::: .: . :
NP_001 VMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTT--TSQAR-ELRVPVG
610 620 630 640 650
790 800 810 820 830 840
pF1KA0 FFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLD
::.:::.::::: .:::.. ::: :...::.::::::::..: ..: :: : . .::
NP_001 FFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLH
660 670 680 690 700 710
850 860 870 880 890
pF1KA0 RLYEHYPAEF-----PCRILLCENYRSHEAIINYTSELFYEGK---LMASGKQPAHKDFY
::. : : :... :::: .::... :. :: .: . : :: : : :
NP_001 RLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHY
720 730 740 750 760 770
900 910 920 930 940 950
pF1KA0 PLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYAD
:: : . : .. . ... : ::. .:::.:.: :: :: .. : ::. ..
NP_001 PLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVS-HGA
780 790 800 810 820 830
960 970 980 990 1000 1010
pF1KA0 QVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLED
:: .: :::.. :..:.: . :.::::. :::: :::. .: .
NP_001 QVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTV---HTCQSLLSPGALAPE----
840 850 860 870 880 890
1020 1030 1040 1050 1060 1070
pF1KA0 STEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL-
:... ..:::..::::: ..:::: .::::.: : :.:: :: : : :.
NP_001 --------FFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVC
900 910 920 930 940
1080 1090 1100 1110 1120 1130
pF1KA0 -HGITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHT
.:...::..
NP_001 PEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGD
950 960 970 980 990 1000
>--
initn: 409 init1: 155 opt: 391 Z-score: 197.8 bits: 50.5 E(85289): 0.00028
Smith-Waterman score: 400; 26.7% identity (51.4% similar) in 619 aa overlap (546-1077:2047-2633)
520 530 540 550 560 570
pF1KA0 TLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKEYIFLR-LSRE
::: .. : . ..:.. .. :
NP_001 APTASPRPGPSSLGPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMGME
2020 2030 2040 2050 2060 2070
580 590 600 610 620
pF1KA0 CCEELNLRPDCDTQVELQFQLNRLPLCEMHYALDRIKDNGVLFPDISMTPTIPWS-----
: ::: ::: . .:: . . :. ... . : .:.. .:
NP_001 KVPEEVLRPGTLFTVELLPK--QLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVI
2080 2090 2100 2110 2120 2130
630 640 650 660 670
pF1KA0 PNRQWDEQLD--P----RLNAKQKEAVLAITTPLAIQLPPVLIIGPYGTGKT-------F
:.: ..: : .:: .:. :: :.. : ..: :: ::::: :
NP_001 PSRFLERQTYNIPGGRHKLNPSQNVAVRE-----ALEKPFTVIQGPPGTGKTIVGLHIVF
2140 2150 2160 2170 2180
680 690 700 710
pF1KA0 TLAQAVKHILQ-----QQETR-----ILICTHSNSAAD----LYIKDY-LHP---YVEAG
. .. .. .: . : : :: : ::...: : .. . :.: : : .
NP_001 WFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQA
2190 2200 2210 2220 2230 2240
720 730 740 750
pF1KA0 NPQARPL-RVYFR------------NRWVKTV---HPVVHQYCLISSAHSTF-------Q
. . :. :: : :. .... : . . :: ..: .
NP_001 EASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGE
2250 2260 2270 2280 2290 2300
760 770 780 790
pF1KA0 MPQKEDIL---------------KHRVVVVTLN--TSQYLCQLDLEPGFFTHILLDEAAQ
. ..::.. .:.:.. : . .: : ::.. .::.:::..
NP_001 LFSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVR-----QILVDEAGM
2310 2320 2330 2340 2350 2360
800 810 820 830 840 850
pF1KA0 AMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDR-LYEHYPAEFP
: : ::..::. : ..:: ::: :: : : .: : .:: ::: :.:.: .
NP_001 ATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNE--RLQNLG---LDRSLFERYHEDAH
2370 2380 2390 2400 2410
860 870 880 890 900
pF1KA0 CRILLCENYRSHEAIINYTSELFYEGKLMA-SG-KQP------AHKDFYPLTFFTARGED
.: .:: ::.: . : ::..:: . .: ..: : :. :. : ..:..
NP_001 ---MLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHE
2420 2430 2440 2450 2460 2470
910 920 930 940 950 960
pF1KA0 VQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGK-LDDGSIGVVTPYADQVFRIRAELR
. :: :. .. : .: .: .. :. .. .:.:.::: :. .: ::
NP_001 RSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALR
2480 2490 2500 2510 2520 2530
970 980 990 1000 1010 1020
pF1KA0 KKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFL
.. .. : : . . ::...: ...::::: : : :. . . ::.
NP_001 REGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKF--------LGFV
2540 2550 2560 2570 2580
1030 1040 1050 1060 1070 1080
pF1KA0 SNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHGITFEQIKAQ
. . .:.:.:::: . ..:: . : :: .:. .. .:. ...:
NP_001 VDPNQVNVAVTRAQEGLCLIGDHLLL----RCCPLWRSLLDFCEAQQTLVPAGQVRVCRR
2590 2600 2610 2620 2630 2640
1090 1100 1110 1120 1130 1140
pF1KA0 LEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQNDHFQNDGIVQ
NP_001 PTMPS
1942 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 17:57:42 2016 done: Wed Nov 2 17:57:45 2016
Total Scan time: 20.810 Total Display time: 1.170
Function used was FASTA [36.3.4 Apr, 2011]