Result of FASTA (omim) for
pFN21AB6855
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6855, 178 aa
1>>>pF1KB6855 178 - 178 aa - 178 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9349+/-0.000309; mu= 15.4834+/- 0.019
mean_var=77.9847+/-15.235, 0's: 0 Z-trim(117.0): 62 B-trim: 23 in 1/53
Lambda= 0.145234
statistics sampled from 28653 (28715) to 28653 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.725), E-opt: 0.2 (0.337), width: 16
Scan time: 4.670
The best scores are: opt bits E(85289)
NP_000563 (OMIM: 124092,180300,609423,614395) inte ( 178) 1187 257.5 8.5e-69
NP_061194 (OMIM: 605619) interleukin-20 precursor ( 176) 213 53.4 2.3e-07
XP_005273209 (OMIM: 605619) PREDICTED: interleukin ( 261) 213 53.5 3e-07
NP_060872 (OMIM: 605679) interleukin-26 precursor ( 171) 189 48.3 7.3e-06
XP_011507403 (OMIM: 604136) PREDICTED: interleukin ( 179) 142 38.5 0.007
XP_016855610 (OMIM: 604136) PREDICTED: interleukin ( 179) 142 38.5 0.007
NP_006841 (OMIM: 604136) interleukin-24 isoform 1 ( 206) 142 38.6 0.0077
NP_001172085 (OMIM: 604136) interleukin-24 isoform ( 207) 142 38.6 0.0077
>>NP_000563 (OMIM: 124092,180300,609423,614395) interleu (178 aa)
initn: 1187 init1: 1187 opt: 1187 Z-score: 1356.1 bits: 257.5 E(85289): 8.5e-69
Smith-Waterman score: 1187; 100.0% identity (100.0% similar) in 178 aa overlap (1-178:1-178)
10 20 30 40 50 60
pF1KB6 MHSSALLCCLVLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMKDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MHSSALLCCLVLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMKDQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGENLKTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGENLKTLR
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 LRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTMKIRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTMKIRN
130 140 150 160 170
>>NP_061194 (OMIM: 605619) interleukin-20 precursor [Hom (176 aa)
initn: 168 init1: 78 opt: 213 Z-score: 253.3 bits: 53.4 E(85289): 2.3e-07
Smith-Waterman score: 213; 27.0% identity (64.2% similar) in 159 aa overlap (19-169:20-173)
10 20 30 40 50
pF1KB6 MHSSALLCCLVLLTGVRASPGQGTQSEN--SCTHFPGNLPNMLRDLRDAFSRVKTFFQM
.:. : .. : ::. . . :...:..::... :
NP_061 MKASSLAFSLLSAAFYLLWTPSTGLKTLNLGSCV-----IATNLQEIRNGFSEIRGSVQA
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 KD-QLDNLLLKESL-LEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGEN
:: ..: .:... :.: : : : .....::..:. . .. : ...::...
NP_061 KDGNIDIRILRRTESLQDTKPANRCCLLRHLLRLYLDRVFKNYQTPDHYTLRKISSLANS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 LKTLRLRLRRCHRFLPC---ENKSKAVEQVKNAFNKLQEKG-IYKAMSEFDIFINYIEAY
. :.. :: :: . : :. : :. . :.::. .. . ::..:.::.....:
NP_061 FLTIKKDLRLCHAHMTCHCGEEAMKKYSQILSHFEKLEPQAAVVKALGELDILLQWMEET
120 130 140 150 160 170
pF1KB6 MTMKIRN
NP_061 E
>>XP_005273209 (OMIM: 605619) PREDICTED: interleukin-20 (261 aa)
initn: 154 init1: 78 opt: 213 Z-score: 251.1 bits: 53.5 E(85289): 3e-07
Smith-Waterman score: 213; 27.0% identity (64.2% similar) in 159 aa overlap (19-169:105-258)
10 20 30 40
pF1KB6 MHSSALLCCLVLLTGVRASPGQGTQSEN--SCTHFPGNLPNMLRDLRD
.:. : .. : ::. . . :...:.
XP_005 LLLWSPDFRPKMKASSLAFSLLSAAFYLLWTPSTGLKTLNLGSCV-----IATNLQEIRN
80 90 100 110 120
50 60 70 80 90 100
pF1KB6 AFSRVKTFFQMKD-QLDNLLLKESL-LEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPD
.::... : :: ..: .:... :.: : : : .....::..:. . .. :
XP_005 GFSEIRGSVQAKDGNIDIRILRRTESLQDTKPANRCCLLRHLLRLYLDRVFKNYQTPDHY
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB6 IKAHVNSLGENLKTLRLRLRRCHRFLPC---ENKSKAVEQVKNAFNKLQEKG-IYKAMSE
...::.... :.. :: :: . : :. : :. . :.::. .. . ::..:
XP_005 TLRKISSLANSFLTIKKDLRLCHAHMTCHCGEEAMKKYSQILSHFEKLEPQAAVVKALGE
190 200 210 220 230 240
170
pF1KB6 FDIFINYIEAYMTMKIRN
.::.....:
XP_005 LDILLQWMEETE
250 260
>>NP_060872 (OMIM: 605679) interleukin-26 precursor [Hom (171 aa)
initn: 92 init1: 78 opt: 189 Z-score: 226.2 bits: 48.3 E(85289): 7.3e-06
Smith-Waterman score: 189; 26.0% identity (60.4% similar) in 169 aa overlap (6-172:6-167)
10 20 30 40 50
pF1KB6 MHSSALLCCLVLLTGVRASPGQGTQSENSCTHFP-GNLPNMLRDLRDAFSRVKTFFQMKD
.: : .::. . . .. :: . . .: :.: . . : . .:. . .:
NP_060 MLVNFILRCGLLLVTLSLAIAKHKQSSFTKSCYPRGTLSQAVDALYIKAAWLKATIP-ED
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 QLDNL-LLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGENLKT
.. :. :::.. ..: . .:: ....:..:.:. : . : : :....
NP_060 RIKNIRLLKKKTKKQF--MKNCQFQEQLLSFFMEDVFGQLQLQGCKKIRFV----EDFHS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 LRLRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTMKIRN
:: .: .: . :.. ..: : .. .::::::.::.::....:. .
NP_060 LRQKLSHCISCASSAREMKSITRMKRIFYRIGNKGIYKAISELDILLSWIKKLLESSQ
120 130 140 150 160 170
>>XP_011507403 (OMIM: 604136) PREDICTED: interleukin-24 (179 aa)
initn: 87 init1: 46 opt: 142 Z-score: 172.8 bits: 38.5 E(85289): 0.007
Smith-Waterman score: 142; 21.9% identity (59.6% similar) in 178 aa overlap (6-174:5-179)
10 20 30 40 50
pF1KB6 MHSSALLCCL--VLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMK
.: :: .:: ..: .:: . . . . : .: . : .:: :: .: .
XP_011 MQMVVLPCLGFTLLLWSQVSGAQGQEFHFGPCQVKGVVP---QKLWEAFWAVKDTMQAQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 DQLDNL-LLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKA--HVNSLGEN
:.. . ::.. .:.. . .: . ...:::. :. . .:. .... ..:..:
XP_011 DNITSARLLQQEVLQNVSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 LKTLRLRLRRCHR---FLPCENKSKAVEQVKNAFNKLQ-EKGIYKAMSEFDIFINYIEAY
. . .:. .. : .. . . ::..:. : .. ::..: ::...... .
XP_011 FVLIVSQLQPSQENEMFSIRDSAHRRFLLFRRAFKQLDVEAALTKALGEVDILLTWMQKF
120 130 140 150 160 170
pF1KB6 MTMKIRN
. .
XP_011 YKL
>>XP_016855610 (OMIM: 604136) PREDICTED: interleukin-24 (179 aa)
initn: 87 init1: 46 opt: 142 Z-score: 172.8 bits: 38.5 E(85289): 0.007
Smith-Waterman score: 142; 21.9% identity (59.6% similar) in 178 aa overlap (6-174:5-179)
10 20 30 40 50
pF1KB6 MHSSALLCCL--VLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMK
.: :: .:: ..: .:: . . . . : .: . : .:: :: .: .
XP_016 MQMVVLPCLGFTLLLWSQVSGAQGQEFHFGPCQVKGVVP---QKLWEAFWAVKDTMQAQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 DQLDNL-LLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKA--HVNSLGEN
:.. . ::.. .:.. . .: . ...:::. :. . .:. .... ..:..:
XP_016 DNITSARLLQQEVLQNVSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 LKTLRLRLRRCHR---FLPCENKSKAVEQVKNAFNKLQ-EKGIYKAMSEFDIFINYIEAY
. . .:. .. : .. . . ::..:. : .. ::..: ::...... .
XP_016 FVLIVSQLQPSQENEMFSIRDSAHRRFLLFRRAFKQLDVEAALTKALGEVDILLTWMQKF
120 130 140 150 160 170
pF1KB6 MTMKIRN
. .
XP_016 YKL
>>NP_006841 (OMIM: 604136) interleukin-24 isoform 1 prec (206 aa)
initn: 87 init1: 46 opt: 142 Z-score: 172.0 bits: 38.6 E(85289): 0.0077
Smith-Waterman score: 142; 21.9% identity (59.6% similar) in 178 aa overlap (6-174:32-206)
10 20 30
pF1KB6 MHSSALLCCL--VLLTGVRASPGQGTQSENSCTHF
.: :: .:: ..: .:: . . . .
NP_006 NFQQRLQSLWTLARPFCPPLLATASQMQMVVLPCLGFTLLLWSQVSGAQGQEFHFGPCQV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 PGNLPNMLRDLRDAFSRVKTFFQMKDQLDNL-LLKESLLEDFKGYLGCQALSEMIQFYLE
: .: . : .:: :: .: .:.. . ::.. .:.. . .: . ...:::.
NP_006 KGVVP---QKLWEAFWAVKDTMQAQDNITSARLLQQEVLQNVSDAESCYLVHTLLEFYLK
70 80 90 100 110
100 110 120 130 140
pF1KB6 EVMPQAENQDPDIKA--HVNSLGENLKTLRLRLRRCHR---FLPCENKSKAVEQVKNAFN
:. . .:. .... ..:..:. . .:. .. : .. . . ::.
NP_006 TVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEMFSIRDSAHRRFLLFRRAFK
120 130 140 150 160 170
150 160 170
pF1KB6 KLQ-EKGIYKAMSEFDIFINYIEAYMTMKIRN
.:. : .. ::..: ::...... .. .
NP_006 QLDVEAALTKALGEVDILLTWMQKFYKL
180 190 200
>>NP_001172085 (OMIM: 604136) interleukin-24 isoform 3 p (207 aa)
initn: 87 init1: 46 opt: 142 Z-score: 172.0 bits: 38.6 E(85289): 0.0077
Smith-Waterman score: 142; 21.9% identity (59.6% similar) in 178 aa overlap (6-174:33-207)
10 20 30
pF1KB6 MHSSALLCCL--VLLTGVRASPGQGTQSENSCTHF
.: :: .:: ..: .:: . . . .
NP_001 FQQRLQSLWTLASRPFCPPLLATASQMQMVVLPCLGFTLLLWSQVSGAQGQEFHFGPCQV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 PGNLPNMLRDLRDAFSRVKTFFQMKDQLDNL-LLKESLLEDFKGYLGCQALSEMIQFYLE
: .: . : .:: :: .: .:.. . ::.. .:.. . .: . ...:::.
NP_001 KGVVP---QKLWEAFWAVKDTMQAQDNITSARLLQQEVLQNVSDAESCYLVHTLLEFYLK
70 80 90 100 110
100 110 120 130 140
pF1KB6 EVMPQAENQDPDIKA--HVNSLGENLKTLRLRLRRCHR---FLPCENKSKAVEQVKNAFN
:. . .:. .... ..:..:. . .:. .. : .. . . ::.
NP_001 TVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEMFSIRDSAHRRFLLFRRAFK
120 130 140 150 160 170
150 160 170
pF1KB6 KLQ-EKGIYKAMSEFDIFINYIEAYMTMKIRN
.:. : .. ::..: ::...... .. .
NP_001 QLDVEAALTKALGEVDILLTWMQKFYKL
180 190 200
178 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 20:11:11 2016 done: Sat Nov 5 20:11:12 2016
Total Scan time: 4.670 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]