Result of FASTA (omim) for
pFN21AE0549
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0549, 154 aa
1>>>pF1KE0549 154 - 154 aa - 154 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7039+/-0.000278; mu= 15.9445+/- 0.017
mean_var=67.2768+/-13.259, 0's: 0 Z-trim(119.1): 124 B-trim: 0 in 0/57
Lambda= 0.156366
statistics sampled from 32614 (32744) to 32614 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.384), width: 16
Scan time: 5.290
The best scores are: opt bits E(85289)
NP_003338 (OMIM: 603721) ubiquitin-conjugating enz ( 154) 1056 246.0 1.8e-65
NP_001243284 (OMIM: 603721) ubiquitin-conjugating ( 212) 1006 234.9 5.5e-62
NP_001243285 (OMIM: 603721) ubiquitin-conjugating ( 122) 787 185.3 2.7e-47
XP_016884424 (OMIM: 603721) PREDICTED: ubiquitin-c ( 121) 714 168.8 2.5e-42
NP_004214 (OMIM: 603890) ubiquitin/ISG15-conjugati ( 153) 594 141.8 4.1e-34
NP_003329 (OMIM: 602961) ubiquitin-conjugating enz ( 147) 404 98.9 3.2e-21
NP_003330 (OMIM: 602962) ubiquitin-conjugating enz ( 147) 399 97.8 7e-21
NP_871621 (OMIM: 602963) ubiquitin-conjugating enz ( 148) 393 96.4 1.8e-20
NP_871617 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 391 96.0 2.4e-20
NP_871618 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 391 96.0 2.4e-20
NP_871620 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 391 96.0 2.4e-20
NP_871619 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 391 96.0 2.4e-20
NP_871616 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 391 96.0 2.4e-20
NP_003331 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 391 96.0 2.4e-20
NP_871615 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 391 96.0 2.4e-20
XP_016865309 (OMIM: 602962) PREDICTED: ubiquitin-c ( 173) 389 95.6 3.8e-20
NP_862821 (OMIM: 602962) ubiquitin-conjugating enz ( 118) 387 95.0 3.9e-20
NP_871622 (OMIM: 602963) ubiquitin-conjugating enz ( 149) 387 95.1 4.6e-20
XP_016864073 (OMIM: 602963) PREDICTED: ubiquitin-c ( 118) 381 93.7 1e-19
NP_001287724 (OMIM: 602963) ubiquitin-conjugating ( 118) 381 93.7 1e-19
XP_016872098 (OMIM: 602961) PREDICTED: ubiquitin-c ( 110) 369 90.9 6.2e-19
NP_001191809 (OMIM: 602961) ubiquitin-conjugating ( 109) 368 90.7 7.2e-19
NP_937826 (OMIM: 603890) ubiquitin/ISG15-conjugati ( 87) 348 86.1 1.4e-17
NP_054895 (OMIM: 610538,616435) ubiquitin-conjugat ( 197) 347 86.2 3e-17
NP_001297255 (OMIM: 610538,616435) ubiquitin-conju ( 167) 346 85.9 3.1e-17
NP_003332 (OMIM: 602916) ubiquitin-conjugating enz ( 193) 337 83.9 1.4e-16
XP_005265489 (OMIM: 602163) PREDICTED: ubiquitin-c ( 201) 337 83.9 1.4e-16
NP_689866 (OMIM: 602163) ubiquitin-conjugating enz ( 201) 337 83.9 1.4e-16
NP_001265483 (OMIM: 604151) ubiquitin-conjugating ( 207) 337 83.9 1.5e-16
XP_005246301 (OMIM: 604151) PREDICTED: ubiquitin-c ( 207) 337 83.9 1.5e-16
NP_001265484 (OMIM: 604151) ubiquitin-conjugating ( 207) 337 83.9 1.5e-16
NP_006348 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 337 83.9 1.5e-16
NP_872619 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 337 83.9 1.5e-16
NP_003339 (OMIM: 603679) ubiquitin-conjugating enz ( 152) 333 82.9 2.2e-16
NP_001189405 (OMIM: 602916) ubiquitin-conjugating ( 160) 332 82.7 2.6e-16
NP_872607 (OMIM: 602916) ubiquitin-conjugating enz ( 176) 330 82.3 3.9e-16
NP_003327 (OMIM: 300860,312180) ubiquitin-conjugat ( 152) 308 77.3 1.1e-14
NP_003328 (OMIM: 179095) ubiquitin-conjugating enz ( 152) 303 76.2 2.4e-14
NP_005330 (OMIM: 602846) ubiquitin-conjugating enz ( 200) 296 74.7 8.7e-14
NP_003960 (OMIM: 603173) NEDD8-conjugating enzyme ( 183) 293 74.0 1.3e-13
NP_001269090 (OMIM: 300860,312180) ubiquitin-conju ( 119) 279 70.6 8.5e-13
XP_005265490 (OMIM: 602163) PREDICTED: ubiquitin-c ( 189) 279 70.8 1.2e-12
XP_005265488 (OMIM: 602916) PREDICTED: ubiquitin-c ( 167) 277 70.3 1.5e-12
NP_001104582 (OMIM: 602846) ubiquitin-conjugating ( 157) 273 69.4 2.7e-12
NP_003335 (OMIM: 601082) ubiquitin-conjugating enz ( 183) 264 67.4 1.2e-11
NP_919235 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 256 65.6 3.8e-11
NP_919237 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 256 65.6 3.8e-11
NP_919236 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 256 65.6 3.8e-11
NP_003336 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 256 65.6 3.8e-11
XP_016879129 (OMIM: 601661) PREDICTED: SUMO-conjug ( 158) 256 65.6 3.8e-11
>>NP_003338 (OMIM: 603721) ubiquitin-conjugating enzyme (154 aa)
initn: 1056 init1: 1056 opt: 1056 Z-score: 1296.6 bits: 246.0 E(85289): 1.8e-65
Smith-Waterman score: 1056; 100.0% identity (100.0% similar) in 154 aa overlap (1-154:1-154)
10 20 30 40 50 60
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP
70 80 90 100 110 120
130 140 150
pF1KE0 LRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
::::::::::::::::::::::::::::::::::
NP_003 LRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
130 140 150
>>NP_001243284 (OMIM: 603721) ubiquitin-conjugating enzy (212 aa)
initn: 1003 init1: 1003 opt: 1006 Z-score: 1233.8 bits: 234.9 E(85289): 5.5e-62
Smith-Waterman score: 1006; 94.9% identity (96.8% similar) in 156 aa overlap (1-154:57-212)
10 20
pF1KE0 MAASRRLM--KELEEIRKCGMKNFRNIQVD
.:. :: .:::::::::::::::::::
NP_001 VLGQRRARLLRQVPSALAGKDLAQLQAGATLAGYRRAHGPEELEEIRKCGMKNFRNIQVD
30 40 50 60 70 80
30 40 50 60 70 80
pF1KE0 EANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLP
90 100 110 120 130 140
90 100 110 120 130 140
pF1KE0 VISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYG
150 160 170 180 190 200
150
pF1KE0 EKRPVD
::::::
NP_001 EKRPVD
210
>>NP_001243285 (OMIM: 603721) ubiquitin-conjugating enzy (122 aa)
initn: 787 init1: 787 opt: 787 Z-score: 970.0 bits: 185.3 E(85289): 2.7e-47
Smith-Waterman score: 787; 97.4% identity (99.1% similar) in 116 aa overlap (39-154:7-122)
10 20 30 40 50 60
pF1KE0 KELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKI
.. :::::::::::::::::::::::::::
NP_001 MAASRRLMKDNPPYDKGAFRIEINFPAEYPFKPPKI
10 20 30
70 80 90 100 110 120
pF1KE0 TFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEE
40 50 60 70 80 90
130 140 150
pF1KE0 YSKDRKKFCKNAEEFTKKYGEKRPVD
::::::::::::::::::::::::::
NP_001 YSKDRKKFCKNAEEFTKKYGEKRPVD
100 110 120
>>XP_016884424 (OMIM: 603721) PREDICTED: ubiquitin-conju (121 aa)
initn: 714 init1: 714 opt: 714 Z-score: 881.0 bits: 168.8 E(85289): 2.5e-42
Smith-Waterman score: 714; 100.0% identity (100.0% similar) in 103 aa overlap (1-103:1-103)
10 20 30 40 50 60
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP
:::::::::::::::::::::::::::::::::::::::::::
XP_016 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQETSAFPIMASLRSSLEV
70 80 90 100 110 120
130 140 150
pF1KE0 LRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
XP_016 L
>>NP_004214 (OMIM: 603890) ubiquitin/ISG15-conjugating e (153 aa)
initn: 594 init1: 594 opt: 594 Z-score: 733.4 bits: 141.8 E(85289): 4.1e-34
Smith-Waterman score: 594; 55.3% identity (80.3% similar) in 152 aa overlap (1-152:1-152)
10 20 30 40 50 60
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE
: :: :..::::...: .::.. :.::.:.:..:..::.::: :: ..:.:: :
NP_004 MMASMRVVKELEDLQKKPPPYLRNLSSDDANVLVWHALLLPDQPPYHLKAFNLRISFPPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP
:::::: : : :::::::.::.::.:::.::.::::: ::: ::...: .::: :. ..:
NP_004 YPFKPPMIKFTTKIYHPNVDENGQICLPIISSENWKPCTKTCQVLEALNVLVNRPNIREP
70 80 90 100 110 120
130 140 150
pF1KE0 LRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
:: :::. ... . : ::::::: ..: ::
NP_004 LRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS
130 140 150
>>NP_003329 (OMIM: 602961) ubiquitin-conjugating enzyme (147 aa)
initn: 358 init1: 184 opt: 404 Z-score: 502.0 bits: 98.9 E(85289): 3.2e-21
Smith-Waterman score: 404; 39.0% identity (74.7% similar) in 146 aa overlap (3-147:2-145)
10 20 30 40 50
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPA
: .:..::: .... . : . .:. ::. :. : . :. :.: . ..::.
NP_003 MALKRIQKELSDLQRDPPAHCSAGPVGD-DLFHWQATIMGPPDSAYQGGVFFLTVHFPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 EYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH
.::::::::.: ::::::::. .:..:: .. .. :.:: ...:. :. .:. ::.:.
NP_003 DYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQ-WSPALTVSKVLLSICSLLCDPNPDD
60 70 80 90 100 110
120 130 140 150
pF1KE0 PLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
:: :.:. :..:..:. ..:.:.:.::
NP_003 PLVPDIAQIYKSDKEKYNRHAREWTQKYAM
120 130 140
>>NP_003330 (OMIM: 602962) ubiquitin-conjugating enzyme (147 aa)
initn: 385 init1: 229 opt: 399 Z-score: 495.9 bits: 97.8 E(85289): 7e-21
Smith-Waterman score: 399; 38.4% identity (73.3% similar) in 146 aa overlap (3-147:2-145)
10 20 30 40 50
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPA
: .:. :::... . . : . ... ::. :. :.. ::. :.: . :.::.
NP_003 MALKRIHKELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 EYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH
.:::::::..: :.::::::. .:..:: .. .. :.:: ..:. :. .:. ::.:.
NP_003 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
120 130 140 150
pF1KE0 PLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
:: ..:. :. ::.:. . :.:.:.::
NP_003 PLVPEIARIYKTDREKYNRIAREWTQKYAM
120 130 140
>>NP_871621 (OMIM: 602963) ubiquitin-conjugating enzyme (148 aa)
initn: 381 init1: 229 opt: 393 Z-score: 488.5 bits: 96.4 E(85289): 1.8e-20
Smith-Waterman score: 393; 38.4% identity (71.9% similar) in 146 aa overlap (3-147:2-145)
10 20 30 40 50
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPA
: .:. ::: .. . . : . ... ::. :. :.. ::. :.: . :.::.
NP_871 MALKRINKELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 EYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH
.:::::::..: :.::::::. .:..:: .. .. :.:: ..:. :. .:. ::.:.
NP_871 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
120 130 140 150
pF1KE0 PLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
:: ..:. :. :: :. . :.:.:.::
NP_871 PLVPEIARIYKTDRDKYNRLAREWTEKYAML
120 130 140
>>NP_871617 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 379 init1: 229 opt: 391 Z-score: 486.1 bits: 96.0 E(85289): 2.4e-20
Smith-Waterman score: 391; 37.7% identity (71.9% similar) in 146 aa overlap (3-147:2-145)
10 20 30 40 50
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPA
: .:. ::: .. . . : . ... ::. :. :.. ::. :.: . :.::.
NP_871 MALKRINKELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 EYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH
.:::::::..: :.::::::. .:..:: .. .. :.:: ..:. :. .:. ::.:.
NP_871 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
120 130 140 150
pF1KE0 PLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
:: ..:. :. :: :. . ..:.:.::
NP_871 PLVPEIARIYKTDRDKYNRISREWTQKYAM
120 130 140
>>NP_871618 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 379 init1: 229 opt: 391 Z-score: 486.1 bits: 96.0 E(85289): 2.4e-20
Smith-Waterman score: 391; 37.7% identity (71.9% similar) in 146 aa overlap (3-147:2-145)
10 20 30 40 50
pF1KE0 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIV-PDNPPYDKGAFRIEINFPA
: .:. ::: .. . . : . ... ::. :. :.. ::. :.: . :.::.
NP_871 MALKRINKELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 EYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEH
.:::::::..: :.::::::. .:..:: .. .. :.:: ..:. :. .:. ::.:.
NP_871 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
120 130 140 150
pF1KE0 PLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
:: ..:. :. :: :. . ..:.:.::
NP_871 PLVPEIARIYKTDRDKYNRISREWTQKYAM
120 130 140
154 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:56:09 2016 done: Wed Nov 2 23:56:10 2016
Total Scan time: 5.290 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]