Result of FASTA (omim) for
pFN21AE0301
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0301, 509 aa
1>>>pF1KE0301 509 - 509 aa - 509 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7866+/-0.000505; mu= 15.5236+/- 0.031
mean_var=75.6707+/-15.972, 0's: 0 Z-trim(108.8): 134 B-trim: 330 in 1/48
Lambda= 0.147438
statistics sampled from 16815 (16960) to 16815 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.551), E-opt: 0.2 (0.199), width: 16
Scan time: 9.300
The best scores are: opt bits E(85289)
NP_036575 (OMIM: 605730) sperm-associated antigen ( 509) 3251 701.7 1.3e-201
XP_005252702 (OMIM: 605730) PREDICTED: sperm-assoc ( 506) 3101 669.8 5.2e-192
NP_001240783 (OMIM: 605730) sperm-associated antig ( 484) 3006 649.6 6.1e-186
NP_001240784 (OMIM: 605730) sperm-associated antig ( 484) 2960 639.8 5.4e-183
NP_758442 (OMIM: 605730) sperm-associated antigen ( 458) 2793 604.2 2.5e-172
XP_005252703 (OMIM: 605730) PREDICTED: sperm-assoc ( 451) 1467 322.2 2e-87
XP_016866329 (OMIM: 604545) PREDICTED: importin su ( 536) 289 71.7 6.3e-12
XP_016866328 (OMIM: 604545) PREDICTED: importin su ( 539) 289 71.7 6.3e-12
NP_002260 (OMIM: 604545) importin subunit alpha-6 ( 539) 289 71.7 6.3e-12
XP_011534107 (OMIM: 604545) PREDICTED: importin su ( 559) 289 71.7 6.5e-12
XP_016866327 (OMIM: 604545) PREDICTED: importin su ( 559) 289 71.7 6.5e-12
NP_002259 (OMIM: 602970) importin subunit alpha-3 ( 521) 283 70.4 1.5e-11
XP_011511097 (OMIM: 600686) PREDICTED: importin su ( 477) 281 69.9 1.8e-11
XP_005247494 (OMIM: 600686) PREDICTED: importin su ( 538) 281 70.0 2e-11
NP_002255 (OMIM: 600686) importin subunit alpha-5 ( 538) 281 70.0 2e-11
XP_016867704 (OMIM: 614107) PREDICTED: importin su ( 487) 280 69.7 2.2e-11
NP_036448 (OMIM: 610563) importin subunit alpha-7 ( 536) 269 67.4 1.2e-10
XP_005270768 (OMIM: 610563) PREDICTED: importin su ( 566) 269 67.4 1.2e-10
XP_016861854 (OMIM: 600686) PREDICTED: importin su ( 337) 241 61.3 5e-09
XP_016861852 (OMIM: 600686) PREDICTED: importin su ( 337) 241 61.3 5e-09
XP_005247496 (OMIM: 600686) PREDICTED: importin su ( 337) 241 61.3 5e-09
XP_011511099 (OMIM: 600686) PREDICTED: importin su ( 337) 241 61.3 5e-09
XP_016861853 (OMIM: 600686) PREDICTED: importin su ( 337) 241 61.3 5e-09
NP_002257 (OMIM: 600685) importin subunit alpha-1 ( 529) 228 58.7 5e-08
NP_001307540 (OMIM: 600685) importin subunit alpha ( 529) 228 58.7 5e-08
XP_016866330 (OMIM: 604545) PREDICTED: importin su ( 332) 210 54.8 4.8e-07
XP_016867705 (OMIM: 614107) PREDICTED: importin su ( 425) 209 54.6 6.8e-07
XP_016866331 (OMIM: 604545) PREDICTED: importin su ( 327) 207 54.1 7.3e-07
XP_016866332 (OMIM: 604545) PREDICTED: importin su ( 327) 207 54.1 7.3e-07
NP_001139187 (OMIM: 614107) importin subunit alpha ( 516) 209 54.6 8e-07
XP_016867703 (OMIM: 614107) PREDICTED: importin su ( 521) 209 54.6 8.1e-07
XP_016867702 (OMIM: 614107) PREDICTED: importin su ( 521) 209 54.6 8.1e-07
XP_016867701 (OMIM: 614107) PREDICTED: importin su ( 521) 209 54.6 8.1e-07
XP_016867700 (OMIM: 614107) PREDICTED: importin su ( 522) 209 54.6 8.1e-07
XP_016867699 (OMIM: 614107) PREDICTED: importin su ( 537) 209 54.6 8.3e-07
XP_011514517 (OMIM: 614107) PREDICTED: importin su ( 543) 209 54.6 8.4e-07
XP_016867697 (OMIM: 614107) PREDICTED: importin su ( 548) 209 54.6 8.4e-07
XP_016867698 (OMIM: 614107) PREDICTED: importin su ( 544) 193 51.2 8.9e-06
XP_016876050 (OMIM: 601892) PREDICTED: importin su ( 497) 184 49.3 3.1e-05
NP_002258 (OMIM: 601892) importin subunit alpha-4 ( 521) 184 49.3 3.2e-05
XP_016858908 (OMIM: 609803) PREDICTED: ankyrin and ( 898) 183 49.2 6e-05
XP_011508976 (OMIM: 609803) PREDICTED: ankyrin and (1434) 183 49.3 8.9e-05
NP_653309 (OMIM: 609803) ankyrin and armadillo rep (1434) 183 49.3 8.9e-05
XP_016858909 (OMIM: 609803) PREDICTED: ankyrin and ( 738) 150 42.2 0.0065
XP_016871860 (OMIM: 615408,615451) PREDICTED: arma ( 701) 149 41.9 0.0072
XP_011517837 (OMIM: 615408,615451) PREDICTED: arma ( 702) 149 41.9 0.0073
NP_001299618 (OMIM: 615408,615451) armadillo repea ( 736) 149 41.9 0.0076
XP_011517836 (OMIM: 615408,615451) PREDICTED: arma ( 756) 149 42.0 0.0077
XP_011517835 (OMIM: 615408,615451) PREDICTED: arma ( 756) 149 42.0 0.0077
XP_016858907 (OMIM: 609803) PREDICTED: ankyrin and ( 909) 150 42.2 0.0078
>>NP_036575 (OMIM: 605730) sperm-associated antigen 6 is (509 aa)
initn: 3251 init1: 3251 opt: 3251 Z-score: 3740.5 bits: 701.7 E(85289): 1.3e-201
Smith-Waterman score: 3251; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:1-509)
10 20 30 40 50 60
pF1KE0 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC
430 440 450 460 470 480
490 500
pF1KE0 YPEEIVRYYSPGYSDTLLQRVDSYQPLNN
:::::::::::::::::::::::::::::
NP_036 YPEEIVRYYSPGYSDTLLQRVDSYQPLNN
490 500
>>XP_005252702 (OMIM: 605730) PREDICTED: sperm-associate (506 aa)
initn: 3773 init1: 3101 opt: 3101 Z-score: 3568.2 bits: 669.8 E(85289): 5.2e-192
Smith-Waterman score: 3101; 99.2% identity (99.4% similar) in 491 aa overlap (1-491:1-491)
10 20 30 40 50 60
pF1KE0 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC
430 440 450 460 470 480
490 500
pF1KE0 YPEEIVRYYSPGYSDTLLQRVDSYQPLNN
:::::: . :
XP_005 YPEEIVSKFFPELQVCALFRKFMRTP
490 500
>>NP_001240783 (OMIM: 605730) sperm-associated antigen 6 (484 aa)
initn: 3006 init1: 3006 opt: 3006 Z-score: 3459.2 bits: 649.6 E(85289): 6.1e-186
Smith-Waterman score: 3006; 100.0% identity (100.0% similar) in 470 aa overlap (40-509:15-484)
10 20 30 40 50 60
pF1KE0 FEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLA
::::::::::::::::::::::::::::::
NP_001 MHSLTMDLWIPNGQAGVMSLLRTLLLDVVPTIQQTAALALGRLA
10 20 30 40
70 80 90 100 110 120
pF1KE0 NYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 LVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIAAS
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 ALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE0 AEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNT
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE0 RLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPE
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE0 HARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPFLYDAPPNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPFLYDAPPNIL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE0 KHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSCYPEEIVRYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSCYPEEIVRYY
410 420 430 440 450 460
490 500
pF1KE0 SPGYSDTLLQRVDSYQPLNN
::::::::::::::::::::
NP_001 SPGYSDTLLQRVDSYQPLNN
470 480
>>NP_001240784 (OMIM: 605730) sperm-associated antigen 6 (484 aa)
initn: 3632 init1: 2960 opt: 2960 Z-score: 3406.4 bits: 639.8 E(85289): 5.4e-183
Smith-Waterman score: 2960; 99.1% identity (99.4% similar) in 469 aa overlap (23-491:1-469)
10 20 30 40 50 60
pF1KE0 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT
::::::::::::::::::::::::::::::::::::::
NP_001 MVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT
10 20 30
70 80 90 100 110 120
pF1KE0 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE0 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE0 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE0 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE0 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE0 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC
400 410 420 430 440 450
490 500
pF1KE0 YPEEIVRYYSPGYSDTLLQRVDSYQPLNN
:::::: . :
NP_001 YPEEIVSKFFPELQVCALFRKFMRTP
460 470 480
>>NP_758442 (OMIM: 605730) sperm-associated antigen 6 is (458 aa)
initn: 2793 init1: 2793 opt: 2793 Z-score: 3214.7 bits: 604.2 E(85289): 2.5e-172
Smith-Waterman score: 2793; 100.0% identity (100.0% similar) in 440 aa overlap (1-440:1-440)
10 20 30 40 50 60
pF1KE0 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC
::::::::::::::::::::
NP_758 LYDAPPNILKHVVGQFSKVLFPWIFRYTSAEGGQLSTT
430 440 450
>>XP_005252703 (OMIM: 605730) PREDICTED: sperm-associate (451 aa)
initn: 1467 init1: 1467 opt: 1467 Z-score: 1690.5 bits: 322.2 E(85289): 2e-87
Smith-Waterman score: 2765; 88.6% identity (88.6% similar) in 509 aa overlap (1-509:1-451)
10 20 30 40 50 60
pF1KE0 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHS
::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLK--------------
190 200 210 220
250 260 270 280 290 300
pF1KE0 VDLAEMVVEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKHTPELSQLVVNAGGVAAVID
::::::::::::::::
XP_005 --------------------------------------------LSQLVVNAGGVAAVID
230 240
310 320 330 340 350 360
pF1KE0 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CIGSCKGNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWAL
250 260 270 280 290 300
370 380 390 400 410 420
pF1KE0 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQIGRHTPEHARAVAVTNTLPVLLSLYMSTESSEDLQVKSKKAIKNILQKCTYLPALEPF
310 320 330 340 350 360
430 440 450 460 470 480
pF1KE0 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINSC
370 380 390 400 410 420
490 500
pF1KE0 YPEEIVRYYSPGYSDTLLQRVDSYQPLNN
:::::::::::::::::::::::::::::
XP_005 YPEEIVRYYSPGYSDTLLQRVDSYQPLNN
430 440 450
>>XP_016866329 (OMIM: 604545) PREDICTED: importin subuni (536 aa)
initn: 333 init1: 169 opt: 289 Z-score: 335.2 bits: 71.7 E(85289): 6.3e-12
Smith-Waterman score: 289; 25.0% identity (58.7% similar) in 264 aa overlap (41-300:167-428)
20 30 40 50 60 70
pF1KE0 EQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLAN
:.. .. :: . .:. :. ::: .:.
XP_016 ENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAG
140 150 160 170 180 190
80 90 100 110 120
pF1KE0 YNDDLAEAVVKCDILPQLVYSLAEQNRFYK-KAAAFVLRAV--GKHSPQLAQAIVDCGAL
: . . :..:.::: :. :...::. . :...: . ::. : . . : :
XP_016 DNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPC--L
200 210 220 230 240 250
130 140 150 160 170 180
pF1KE0 DTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIA
..: : . :: : . ::: :.. . :::.:.:. :: ... . . :
XP_016 NVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPA
260 270 280 290 300 310
190 200 210 220 230 240
pF1KE0 ASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMV
:...:. . .:.... .:. : ... .: ..... ..:... . . :
XP_016 LRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAV
320 330 340 350 360 370
250 260 270 280 290 300
pF1KE0 VEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKH-TPELSQLVVNAGGVAAVIDCIGSCK
..:.::::.. :. . ..:.:. : . .. ::: . .: : . . :
XP_016 IDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMD
380 390 400 410 420 430
310 320 330 340 350 360
pF1KE0 GNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQIGRH
XP_016 SKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQSHENQEIYQKA
440 450 460 470 480 490
>>XP_016866328 (OMIM: 604545) PREDICTED: importin subuni (539 aa)
initn: 262 init1: 169 opt: 289 Z-score: 335.1 bits: 71.7 E(85289): 6.3e-12
Smith-Waterman score: 289; 25.0% identity (58.7% similar) in 264 aa overlap (41-300:170-431)
20 30 40 50 60 70
pF1KE0 EQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLAN
:.. .. :: . .:. :. ::: .:.
XP_016 ENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAG
140 150 160 170 180 190
80 90 100 110 120
pF1KE0 YNDDLAEAVVKCDILPQLVYSLAEQNRFYK-KAAAFVLRAV--GKHSPQLAQAIVDCGAL
: . . :..:.::: :. :...::. . :...: . ::. : . . : :
XP_016 DNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPC--L
200 210 220 230 240 250
130 140 150 160 170 180
pF1KE0 DTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIA
..: : . :: : . ::: :.. . :::.:.:. :: ... . . :
XP_016 NVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPA
260 270 280 290 300 310
190 200 210 220 230 240
pF1KE0 ASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMV
:...:. . .:.... .:. : ... .: ..... ..:... . . :
XP_016 LRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAV
320 330 340 350 360 370
250 260 270 280 290 300
pF1KE0 VEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKH-TPELSQLVVNAGGVAAVIDCIGSCK
..:.::::.. :. . ..:.:. : . .. ::: . .: : . . :
XP_016 IDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMD
380 390 400 410 420 430
310 320 330 340 350 360
pF1KE0 GNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQIGRH
XP_016 SKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQSHENQEIYQKA
440 450 460 470 480 490
>>NP_002260 (OMIM: 604545) importin subunit alpha-6 [Hom (539 aa)
initn: 262 init1: 169 opt: 289 Z-score: 335.1 bits: 71.7 E(85289): 6.3e-12
Smith-Waterman score: 289; 25.0% identity (58.7% similar) in 264 aa overlap (41-300:170-431)
20 30 40 50 60 70
pF1KE0 EQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLAN
:.. .. :: . .:. :. ::: .:.
NP_002 ENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAG
140 150 160 170 180 190
80 90 100 110 120
pF1KE0 YNDDLAEAVVKCDILPQLVYSLAEQNRFYK-KAAAFVLRAV--GKHSPQLAQAIVDCGAL
: . . :..:.::: :. :...::. . :...: . ::. : . . : :
NP_002 DNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPC--L
200 210 220 230 240 250
130 140 150 160 170 180
pF1KE0 DTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIA
..: : . :: : . ::: :.. . :::.:.:. :: ... . . :
NP_002 NVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPA
260 270 280 290 300 310
190 200 210 220 230 240
pF1KE0 ASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMV
:...:. . .:.... .:. : ... .: ..... ..:... . . :
NP_002 LRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAV
320 330 340 350 360 370
250 260 270 280 290 300
pF1KE0 VEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKH-TPELSQLVVNAGGVAAVIDCIGSCK
..:.::::.. :. . ..:.:. : . .. ::: . .: : . . :
NP_002 IDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMD
380 390 400 410 420 430
310 320 330 340 350 360
pF1KE0 GNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQIGRH
NP_002 SKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQSHENQEIYQKA
440 450 460 470 480 490
>>XP_011534107 (OMIM: 604545) PREDICTED: importin subuni (559 aa)
initn: 333 init1: 169 opt: 289 Z-score: 334.9 bits: 71.7 E(85289): 6.5e-12
Smith-Waterman score: 289; 25.0% identity (58.7% similar) in 264 aa overlap (41-300:190-451)
20 30 40 50 60 70
pF1KE0 EQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRTLLLDVVPTIQQTAALALGRLAN
:.. .. :: . .:. :. ::: .:.
XP_011 ENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAG
160 170 180 190 200 210
80 90 100 110 120
pF1KE0 YNDDLAEAVVKCDILPQLVYSLAEQNRFYK-KAAAFVLRAV--GKHSPQLAQAIVDCGAL
: . . :..:.::: :. :...::. . :...: . ::. : . . : :
XP_011 DNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPC--L
220 230 240 250 260 270
130 140 150 160 170 180
pF1KE0 DTLVICLEDFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEPEIALKRIA
..: : . :: : . ::: :.. . :::.:.:. :: ... . . :
XP_011 NVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPA
280 290 300 310 320 330
190 200 210 220 230 240
pF1KE0 ASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMV
:...:. . .:.... .:. : ... .: ..... ..:... . . :
XP_011 LRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAV
340 350 360 370 380 390
250 260 270 280 290 300
pF1KE0 VEAEIFPVVLTCLKDKDEYVKKNASTLIREIAKH-TPELSQLVVNAGGVAAVIDCIGSCK
..:.::::.. :. . ..:.:. : . .. ::: . .: : . . :
XP_011 IDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMD
400 410 420 430 440 450
310 320 330 340 350 360
pF1KE0 GNTRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSVCLSEEPEDHIKAAAAWALGQIGRH
XP_011 SKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQSHENQEIYQKA
460 470 480 490 500 510
509 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:26:39 2016 done: Thu Nov 3 17:26:40 2016
Total Scan time: 9.300 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]