Result of FASTA (ccds) for
pFN21AE0042
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0042, 511 aa
1>>>pF1KE0042 511 - 511 aa - 511 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4057+/-0.000741; mu= 14.1701+/- 0.045
mean_var=96.5402+/-19.207, 0's: 0 Z-trim(110.9): 31 B-trim: 9 in 2/51
Lambda= 0.130533
statistics sampled from 11945 (11975) to 11945 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.368), width: 16
Scan time: 2.940
The best scores are: opt bits E(32554)
CCDS58130.1 PRDM11 gene_id:56981|Hs108|chr11 ( 477) 3264 624.7 6.8e-179
CCDS73277.1 PRDM11 gene_id:56981|Hs108|chr11 (1177) 3116 597.1 3.6e-170
CCDS43307.1 PRDM9 gene_id:56979|Hs108|chr5 ( 894) 535 111.0 5.9e-24
CCDS45557.1 PRDM7 gene_id:11105|Hs108|chr16 ( 492) 531 110.1 6e-24
CCDS42932.1 PRDM15 gene_id:63977|Hs108|chr21 (1178) 349 76.0 2.6e-13
CCDS63370.1 PRDM15 gene_id:63977|Hs108|chr21 (1198) 349 76.0 2.6e-13
CCDS5054.2 PRDM1 gene_id:639|Hs108|chr6 ( 825) 317 69.9 1.3e-11
CCDS9115.1 PRDM4 gene_id:11108|Hs108|chr12 ( 801) 303 67.2 7.6e-11
>>CCDS58130.1 PRDM11 gene_id:56981|Hs108|chr11 (477 aa)
initn: 3264 init1: 3264 opt: 3264 Z-score: 3325.1 bits: 624.7 E(32554): 6.8e-179
Smith-Waterman score: 3264; 100.0% identity (100.0% similar) in 477 aa overlap (35-511:1-477)
10 20 30 40 50 60
pF1KE0 AEPIASLMIVECRACLRCSPLFLYQREKDRMTENMKECLAQTNAAVGDMVTVVKTEVCSP
::::::::::::::::::::::::::::::
CCDS58 MTENMKECLAQTNAAVGDMVTVVKTEVCSP
10 20 30
70 80 90 100 110 120
pF1KE0 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE0 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE0 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE0 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE0 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE0 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP
400 410 420 430 440 450
490 500 510
pF1KE0 EFSDPAGKLVWMRLLSEGRVRSGLCGG
:::::::::::::::::::::::::::
CCDS58 EFSDPAGKLVWMRLLSEGRVRSGLCGG
460 470
>>CCDS73277.1 PRDM11 gene_id:56981|Hs108|chr11 (1177 aa)
initn: 3116 init1: 3116 opt: 3116 Z-score: 3168.6 bits: 597.1 E(32554): 3.6e-170
Smith-Waterman score: 3116; 100.0% identity (100.0% similar) in 456 aa overlap (35-490:1-456)
10 20 30 40 50 60
pF1KE0 AEPIASLMIVECRACLRCSPLFLYQREKDRMTENMKECLAQTNAAVGDMVTVVKTEVCSP
::::::::::::::::::::::::::::::
CCDS73 MTENMKECLAQTNAAVGDMVTVVKTEVCSP
10 20 30
70 80 90 100 110 120
pF1KE0 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNH
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQIS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE0 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 TQDKSAGFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFR
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE0 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGP
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE0 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 IHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLV
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE0 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 IRKVPKYQDDAYSQCATTMTHGVQNIGQTQGEGDWKVPQGVSKEPGQLEDEEEEPSSFKA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE0 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 DSPAEASLASDPHELPTTSFCPNCIRLKKKVRELQAELDMLKSGKLPEPPVLPPQVLELP
400 410 420 430 440 450
490 500 510
pF1KE0 EFSDPAGKLVWMRLLSEGRVRSGLCGG
::::::
CCDS73 EFSDPAASESMVSGPAIMEDDDQEVDSADESVSNDMMTATDEPSKMSSATGRRIRRFKQE
460 470 480 490 500 510
>>CCDS43307.1 PRDM9 gene_id:56979|Hs108|chr5 (894 aa)
initn: 530 init1: 283 opt: 535 Z-score: 543.6 bits: 111.0 E(32554): 5.9e-24
Smith-Waterman score: 535; 44.0% identity (75.0% similar) in 168 aa overlap (103-267:198-365)
80 90 100 110 120 130
pF1KE0 PCSRRPDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNHGPPVFVSD
:. :. .:: ::..:.: : ::::.::.:
CCDS43 KLELRKKETERKMYSLRERKGHAYKEVSEPQDDDYLYCEMCQNFFIDSCAAHGPPTFVKD
170 180 190 200 210 220
140 150 160 170 180 190
pF1KE0 TPVPVGIPDRAALTIPQGMEVVKDTSGESDVRCVNEV--IPKGHIFGPYEGQISTQDKSA
. : : :.:.::..: :... . .. . ::. .: : ::::::.:. ....:
CCDS43 SAVDKGHPNRSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAA
230 240 250 260 270 280
200 210 220 230 240
pF1KE0 GF-FSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFRACRDI
. .::::. : :. .::.:.. ::::::: .:...::::.:::. ..:..:.:: :
CCDS43 NNGYSWLITKGRNCYEYVDGKDKSWANWMRYVNCARDDEEQNLVAFQYHRQIFYRTCRVI
290 300 310 320 330 340
250 260 270 280 290 300
pF1KE0 RPGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGPIHLSV
::: : :::...: ..:
CCDS43 RPGCELLVWYGDEYGQELGIKWGSKWKKELMAGREPKPEIHPCPSCCLAFSSQKFLSQHV
350 360 370 380 390 400
>>CCDS45557.1 PRDM7 gene_id:11105|Hs108|chr16 (492 aa)
initn: 519 init1: 272 opt: 531 Z-score: 543.4 bits: 110.1 E(32554): 6e-24
Smith-Waterman score: 531; 39.6% identity (71.1% similar) in 197 aa overlap (76-267:172-365)
50 60 70 80 90 100
pF1KE0 TNAAVGDMVTVVKTEVCSPLRDQEYGQPCSRRPDSSAMEVEPKKLKGK--RDLIVPKSFQ
:: .. . .. ::. ... : :
CCDS45 TSDSEQAQKPVSPPGEASTSGQHSRLKLELRRKETEGKMYSLRERKGHAYKEISEP---Q
150 160 170 180 190
110 120 130 140 150 160
pF1KE0 QVDFWFCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPQGMEVVKDTSGESDV
. :. .:: ::..:.: : ::::.::.:. : : :.:.::..: :... . .. .
CCDS45 DDDYLYCEMCQNFFIDSCAAHGPPTFVKDSAVDKGHPNRSALSLPPGLRIGPSGIPQAGL
200 210 220 230 240 250
170 180 190 200 210 220
pF1KE0 RCVNEV--IPKGHIFGPYEGQISTQDKSAGF-FSWLIVDKNNRYKSIDGSDETKANWMRY
::. .: : ::::::.:. ....:. .::::. : :. .::.:...::::::
CCDS45 GVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLITKGRNCYEYVDGKDKSSANWMRY
260 270 280 290 300 310
230 240 250 260 270 280
pF1KE0 VVISREEREQNLLAFQHSERIYFRACRDIRPGEWLRVWYSEDYMKRLHSMSQETIHRNLA
: .:...::::.:::. ..:..:.:: :::: : :: ...: ..:
CCDS45 VNCARDDEEQNLVAFQYHRQIFYRTCRVIRPGCELLVWSGDEYGQELGIRSSIEPAESLG
320 330 340 350 360 370
290 300 310 320 330 340
pF1KE0 RGEKRLQREKSEQVLDNPEDLRGPIHLSVLRQGKSPYKRGFDEGDVHPQAKKKKIDLIFK
CCDS45 QAVNCWSGMGMSMARNWASSGAASGRKSSWQGENQSQRSIHVPHAVWPFQVKNFSVNMWN
380 390 400 410 420 430
>>CCDS42932.1 PRDM15 gene_id:63977|Hs108|chr21 (1178 aa)
initn: 305 init1: 220 opt: 349 Z-score: 352.5 bits: 76.0 E(32554): 2.6e-13
Smith-Waterman score: 349; 31.2% identity (59.5% similar) in 205 aa overlap (76-267:4-203)
50 60 70 80 90 100
pF1KE0 TNAAVGDMVTVVKTEVCSPLRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPK-SFQ-
::: .:. :... . .: .::
CCDS42 MPRRRPPASGAAQFPERIATRSPDPIPLCTFQR
10 20 30
110 120 130 140 150
pF1KE0 QVD-----------FWFCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPQGME
::. : .::.:..: .:::. :: :.:.:. : .:: ..: ..:
CCDS42 QVSEMAEDGSEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVL----SRARSSLPPNLE
40 50 60 70 80
160 170 180 190 200 210
pF1KE0 VVKDTSGESDVRCVNEVIPKGHIFGPYEGQISTQDKSAGFFSWLIVDKNNRYKSIDGSDE
. . .: : ..... . . :::.:.. .. .. . : . .:... .: :.:
CCDS42 IRRLEDGAEGVFAITQLVKRTQ-FGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNE
90 100 110 120 130 140
220 230 240 250 260 270
pF1KE0 TKANWMRYVVISREEREQNLLAFQHSERIYFRACRDIRPGEWLRVWYSEDYMKRLHSMSQ
::: : . : ..::: :.::. .:: . ::: :: :::::. : :..
CCDS42 DDCNWMMLVRPAAEAEHQNLTAYQHGSDVYFTTSRDIPPGTELRVWYAAFYAKKMDKPML
150 160 170 180 190 200
280 290 300 310 320 330
pF1KE0 ETIHRNLARGEKRLQREKSEQVLDNPEDLRGPIHLSVLRQGKSPYKRGFDEGDVHPQAKK
CCDS42 KQAGSGVHAAGTPENSAPVESEPSQWACKVCSATFLELQLLNEHLLGHLEQAKSLPPGSQ
210 220 230 240 250 260
>>CCDS63370.1 PRDM15 gene_id:63977|Hs108|chr21 (1198 aa)
initn: 305 init1: 220 opt: 349 Z-score: 352.4 bits: 76.0 E(32554): 2.6e-13
Smith-Waterman score: 349; 31.2% identity (59.5% similar) in 205 aa overlap (76-267:4-203)
50 60 70 80 90 100
pF1KE0 TNAAVGDMVTVVKTEVCSPLRDQEYGQPCSRRPDSSAMEVEPKKLKGKRDLIVPK-SFQ-
::: .:. :... . .: .::
CCDS63 MPRRRPPASGAAQFPERIATRSPDPIPLCTFQR
10 20 30
110 120 130 140 150
pF1KE0 QVD-----------FWFCESCQEYFVDECPNHGPPVFVSDTPVPVGIPDRAALTIPQGME
::. : .::.:..: .:::. :: :.:.:. : .:: ..: ..:
CCDS63 QVSEMAEDGSEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVL----SRARSSLPPNLE
40 50 60 70 80
160 170 180 190 200 210
pF1KE0 VVKDTSGESDVRCVNEVIPKGHIFGPYEGQISTQDKSAGFFSWLIVDKNNRYKSIDGSDE
. . .: : ..... . . :::.:.. .. .. . : . .:... .: :.:
CCDS63 IRRLEDGAEGVFAITQLVKRTQ-FGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNE
90 100 110 120 130 140
220 230 240 250 260 270
pF1KE0 TKANWMRYVVISREEREQNLLAFQHSERIYFRACRDIRPGEWLRVWYSEDYMKRLHSMSQ
::: : . : ..::: :.::. .:: . ::: :: :::::. : :..
CCDS63 DDCNWMMLVRPAAEAEHQNLTAYQHGSDVYFTTSRDIPPGTELRVWYAAFYAKKMDKPML
150 160 170 180 190 200
280 290 300 310 320 330
pF1KE0 ETIHRNLARGEKRLQREKSEQVLDNPEDLRGPIHLSVLRQGKSPYKRGFDEGDVHPQAKK
CCDS63 KQAGSGVHAAGTPENSAPVESEPSQWACKVCSATFLELQLLNEHLLGHLEQAKSLPPGSQ
210 220 230 240 250 260
>>CCDS5054.2 PRDM1 gene_id:639|Hs108|chr6 (825 aa)
initn: 295 init1: 211 opt: 317 Z-score: 322.2 bits: 69.9 E(32554): 1.3e-11
Smith-Waterman score: 317; 30.3% identity (58.8% similar) in 238 aa overlap (109-336:54-281)
80 90 100 110 120 130
pF1KE0 DSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNHGPPVFVSDTPVPVG
: :.: :.:.. : :. . :
CCDS50 VRFQGLAEGTKGTMKMDMEDADMTLWTEAEFEEKCT-YIVNDHPW--------DSGADGG
30 40 50 60 70
140 150 160 170 180 190
pF1KE0 IPDRAALTIPQGMEVVKDTSGESDVRCVN-EVIPKGHIFGPYEGQISTQD---KSAG--F
.: ..:... :..: . .. : :::: ::: :.: :.: :.:. .
CCDS50 TSVQAEASLPRNLLFKYATNSEEVIGVMSKEYIPKGTRFGPLIGEIYTNDTVPKNANRKY
80 90 100 110 120 130
200 210 220 230 240 250
pF1KE0 FSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFRACRDIRPG
: : : .... .. ::: .: :.:::::: .. ::::: : :.. ::: . . : .
CCDS50 F-WRIYSRGELHHFIDGFNEEKSNWMRYVNPAHSPREQNLAACQNGMNIYFYTIKPIPAN
140 150 160 170 180 190
260 270 280 290 300
pF1KE0 EWLRVWYSEDYMKRLH-SMSQETIHRNLARGEKRLQREKSEQVLDNPEDL--RGPIHLSV
. : ::: .:. .::: . : ::.. .. :.. ..:. :... : .
CCDS50 QELLVWYCRDFAERLHYPYPGELTMMNLTQTQSSLKQPSTEKNELCPKNVPKREYSVKEI
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE0 LRQGKSPYK-RGFDEGDVHPQAKKKKIDLIFKDVLEASLESAKVEAHQLALSTSLVIRKV
:. ..: : . . .... : ...: .:
CCDS50 LKLDSNPSKGKDLYRSNISPLTSEKDLDDFRRRGSPEMPFYPRVVYPIRAPLPEDFLKAS
260 270 280 290 300 310
>>CCDS9115.1 PRDM4 gene_id:11108|Hs108|chr12 (801 aa)
initn: 261 init1: 159 opt: 303 Z-score: 308.2 bits: 67.2 E(32554): 7.6e-11
Smith-Waterman score: 303; 32.4% identity (59.7% similar) in 176 aa overlap (108-276:376-545)
80 90 100 110 120 130
pF1KE0 PDSSAMEVEPKKLKGKRDLIVPKSFQQVDFWFCESCQEYFVDECPNHGPPVFVSDTPVPV
: : :.. . ..::.::: .:: :::
CCDS91 SSDSLSFVSPSLQMEDSNSNKENMATLFTIW-CTLCDRAYPSDCPEHGPVTFVPDTP---
350 360 370 380 390 400
140 150 160 170 180 190
pF1KE0 GIPDRAALTIPQGMEVVKDTSGESDVRCVNEVIPKGHIFGPYEGQISTQ-------DKSA
: .:: :..:. . . .. : ..:.:: ::: :: : . ::..
CCDS91 -IESRARLSLPKQLVLRQSIVGAEVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAV
410 420 430 440 450 460
200 210 220 230 240 250
pF1KE0 GFFSWLIVDKNNRYKSIDGSDETKANWMRYVVISREEREQNLLAFQHSERIYFRACRDIR
. . : : .. : .::.. ::: .: .:...::::.:. :. .:.: . .::
CCDS91 NHI-WKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIP
470 480 490 500 510
260 270 280 290 300 310
pF1KE0 PGEWLRVWYSEDYMKRLHSMSQETIHRNLARGEKRLQREKSEQVLDNPEDLRGPIHLSVL
: . : .::.:: ... . .:
CCDS91 PENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQGHSGS
520 530 540 550 560 570
511 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 06:24:50 2016 done: Fri Nov 4 06:24:50 2016
Total Scan time: 2.940 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]