Result of FASTA (ccds) for
pFN21AB8899
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8899, 233 aa
1>>>pF1KB8899 233 - 233 aa - 233 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3032+/-0.000715; mu= 10.1907+/- 0.043
mean_var=104.3497+/-22.032, 0's: 0 Z-trim(112.1): 169 B-trim: 736 in 2/52
Lambda= 0.125553
statistics sampled from 12766 (12952) to 12766 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.398), width: 16
Scan time: 2.050
The best scores are: opt bits E(32554)
CCDS5407.1 HOXA6 gene_id:3203|Hs108|chr7 ( 233) 1616 302.5 1.5e-82
CCDS11531.1 HOXB6 gene_id:3216|Hs108|chr17 ( 224) 589 116.5 1.4e-26
CCDS41792.1 HOXC6 gene_id:3223|Hs108|chr12 ( 153) 513 102.6 1.5e-22
CCDS8871.1 HOXC6 gene_id:3223|Hs108|chr12 ( 235) 513 102.7 2.1e-22
CCDS5406.1 HOXA5 gene_id:3202|Hs108|chr7 ( 270) 462 93.6 1.4e-19
CCDS11532.1 HOXB7 gene_id:3217|Hs108|chr17 ( 217) 455 92.2 2.9e-19
CCDS2269.1 HOXD4 gene_id:3233|Hs108|chr2 ( 255) 445 90.5 1.1e-18
CCDS11530.1 HOXB5 gene_id:3215|Hs108|chr17 ( 269) 435 88.7 4.2e-18
CCDS5408.1 HOXA7 gene_id:3204|Hs108|chr7 ( 230) 428 87.3 8.9e-18
CCDS8873.1 HOXC4 gene_id:3221|Hs108|chr12 ( 264) 422 86.3 2.1e-17
CCDS11529.1 HOXB4 gene_id:3214|Hs108|chr17 ( 251) 421 86.1 2.3e-17
CCDS5405.1 HOXA4 gene_id:3201|Hs108|chr7 ( 320) 418 85.6 4.1e-17
CCDS8872.1 HOXC5 gene_id:3222|Hs108|chr12 ( 222) 413 84.6 5.7e-17
CCDS8870.1 HOXC8 gene_id:3224|Hs108|chr12 ( 242) 408 83.7 1.1e-16
CCDS2268.1 HOXD8 gene_id:3234|Hs108|chr2 ( 290) 388 80.2 1.6e-15
CCDS11533.1 HOXB8 gene_id:3218|Hs108|chr17 ( 243) 381 78.8 3.4e-15
CCDS56148.1 HOXD8 gene_id:3234|Hs108|chr2 ( 289) 380 78.7 4.4e-15
CCDS56149.1 HOXD8 gene_id:3234|Hs108|chr2 ( 106) 358 74.4 3.2e-14
CCDS2267.2 HOXD9 gene_id:3235|Hs108|chr2 ( 352) 338 71.2 1e-12
CCDS8869.1 HOXC9 gene_id:3225|Hs108|chr12 ( 260) 309 65.8 3e-11
CCDS5403.1 HOXA2 gene_id:3199|Hs108|chr7 ( 376) 306 65.4 5.9e-11
CCDS5409.1 HOXA9 gene_id:3205|Hs108|chr7 ( 272) 301 64.4 8.5e-11
CCDS5404.1 HOXA3 gene_id:3200|Hs108|chr7 ( 443) 304 65.1 8.6e-11
>>CCDS5407.1 HOXA6 gene_id:3203|Hs108|chr7 (233 aa)
initn: 1616 init1: 1616 opt: 1616 Z-score: 1595.5 bits: 302.5 E(32554): 1.5e-82
Smith-Waterman score: 1616; 100.0% identity (100.0% similar) in 233 aa overlap (1-233:1-233)
10 20 30 40 50 60
pF1KB8 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 KALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYL
130 140 150 160 170 180
190 200 210 220 230
pF1KB8 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE
190 200 210 220 230
>>CCDS11531.1 HOXB6 gene_id:3216|Hs108|chr17 (224 aa)
initn: 780 init1: 551 opt: 589 Z-score: 590.4 bits: 116.5 E(32554): 1.4e-26
Smith-Waterman score: 815; 57.2% identity (75.8% similar) in 236 aa overlap (1-233:1-224)
10 20 30 40 50
pF1KB8 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGY-DALRPFPASYGASSLPDKTYTSPCFYQ
::::::: ::: .: :::.:::::::::..:: : :: .:: :: . :: ... .:
CCDS11 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKGFATSSYYP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 QSNSVLACNRASY-EYG-ASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSS
... . .::. .:: : :: .:. :. . ::. .: : : :: . : : .
CCDS11 PAGG--GYGRAAPCDYGPAPAFYREKE-SACALSGADEQ--PP----FHPEPR-KSDCA-
70 80 90 100
120 130 140 150 160 170
pF1KB8 GQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFN
: :.. : ..: ..:::::::::::: .. .: :::::::::::::::::::::.:
CCDS11 -QDKSVFGETEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYN
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB8 RYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE
::::::::::::.:::::::::::::::::::::::.::....: :.:. : : .:
CCDS11 RYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQAE
170 180 190 200 210 220
>>CCDS41792.1 HOXC6 gene_id:3223|Hs108|chr12 (153 aa)
initn: 521 init1: 488 opt: 513 Z-score: 518.4 bits: 102.6 E(32554): 1.5e-22
Smith-Waterman score: 513; 67.2% identity (81.0% similar) in 116 aa overlap (114-229:21-133)
90 100 110 120 130 140
pF1KB8 DLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRM
: :: ::.. :.: . .:::::::
CCDS41 MLSNCRQNTLGHNTQTSIAQDFSSEQGRT---APQDQKASIQIYPWMQRM
10 20 30 40
150 160 170 180 190 200
pF1KB8 NSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWF
:: .:. ::. ::::: :.::::::::::::::::::::::::::::::::::::::::
CCDS41 NSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWF
50 60 70 80 90 100
210 220 230
pF1KB8 QNRRMKWKKENKLINSTQPSGEDSEAKAGE
::::::::::..: .. . .: . :
CCDS41 QNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETEEEKQKE
110 120 130 140 150
>>CCDS8871.1 HOXC6 gene_id:3223|Hs108|chr12 (235 aa)
initn: 714 init1: 488 opt: 513 Z-score: 515.7 bits: 102.7 E(32554): 2.1e-22
Smith-Waterman score: 696; 49.8% identity (71.6% similar) in 229 aa overlap (1-229:1-215)
10 20 30 40 50 60
pF1KB8 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQ
:.:::.::.. : .::: : .. : ...:: .: : ..:::. .. :..: . :
CCDS88 MNSYFTNPSLSCHLAGGQD-VLPNVALNSTAYDPVRHF-STYGAAVAQNRIYSTPFYSPQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 SNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQG
: :.. .:. :.::.. ::..::. . . .: : . : : : :: ::
CCDS88 ENVVFSSSRGPYDYGSNSFYQEKDMLS-----NCRQNTLGHNTQTSIAQ----DFSSEQG
60 70 80 90 100
130 140 150 160 170 180
pF1KB8 KALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYL
.. . :.: . .::::::::: .:. ::. ::::: :.:::::::::::::::::
CCDS88 RTAPQ---DQKASIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYL
110 120 130 140 150 160
190 200 210 220 230
pF1KB8 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE
:::::::::::::::::::::::::::::::::..: .. . .: . :
CCDS88 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKRE
170 180 190 200 210 220
CCDS88 ETEEEKQKE
230
>>CCDS5406.1 HOXA5 gene_id:3202|Hs108|chr7 (270 aa)
initn: 492 init1: 444 opt: 462 Z-score: 464.9 bits: 93.6 E(32554): 1.4e-19
Smith-Waterman score: 462; 45.3% identity (66.1% similar) in 192 aa overlap (36-216:71-256)
10 20 30 40 50 60
pF1KB8 VNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLP-DKTYTSPCFYQQSNSV
: . :: ::. : . :..: .: .
CCDS54 HSGRYGYGYNGMDLSVGRSGSGHFGSGERARSYAAS--ASAAPAEPRYSQPATSTHSPQP
50 60 70 80 90
70 80 90 100 110
pF1KB8 --LACNRASYEYGASCFYSDKDL----SGASP-SGS---GKQRGPGDYLHFSPEQQYKPD
: :. .. :.. .. :. :::: .:: ....: : : .. :
CCDS54 DPLPCSAVAPSPGSDSHHGGKNSLSNSSGASADAGSTHISSREGVGTA---SGAEEDAP-
100 110 120 130 140 150
120 130 140 150 160 170
pF1KB8 SSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEF
.:: :..: . . .::::.... . : .:.:.: .:::::::::::::
CCDS54 ASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEF
160 170 180 190 200 210
180 190 200 210 220 230
pF1KB8 HFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE
:::::::::::::::.::::.:::::::::::::::::.:::
CCDS54 HFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP
220 230 240 250 260 270
>>CCDS11532.1 HOXB7 gene_id:3217|Hs108|chr17 (217 aa)
initn: 439 init1: 392 opt: 455 Z-score: 459.4 bits: 92.2 E(32554): 2.9e-19
Smith-Waterman score: 456; 43.3% identity (62.3% similar) in 215 aa overlap (40-233:12-215)
10 20 30 40 50 60
pF1KB8 FPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQSNSVLACNR
..: ::: ..... : .:.. ..: :
CCDS11 MSSLYYANTLFSKYPASS---SVFATGAFPEQTSCAFASNP
10 20 30
70 80 90 100 110
pF1KB8 ASYEYGASCFYS-DKDLSGASPSGSGK--QRGPGDY------------LHFSP-EQQYK-
:::. : ...: :.:.: : . : : .: .: ::. .
CCDS11 QRPGYGAGSGASFAASMQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSG
40 50 60 70 80 90
120 130 140 150 160
pF1KB8 --P-DSSSGQG-KALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTL
: ::... : : .: . . .::::. :. .::::::::::::
CCDS11 VCPGDSAKAAGAKEQRDSDLAAESNFRIYPWMRSS--------GTDRKRGRQTYTRYQTL
100 110 120 130 140 150
170 180 190 200 210 220
pF1KB8 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE
:::::::.:::::::::::::..:::::::::::::::::::::::: . . . .:
CCDS11 ELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKENKTAGPGTTGQDRAE
160 170 180 190 200 210
230
pF1KB8 AKAGE
:. :
CCDS11 AEEEEEE
>>CCDS2269.1 HOXD4 gene_id:3233|Hs108|chr2 (255 aa)
initn: 449 init1: 366 opt: 445 Z-score: 448.6 bits: 90.5 E(32554): 1.1e-18
Smith-Waterman score: 447; 39.1% identity (54.8% similar) in 248 aa overlap (1-231:3-230)
10 20 30 40 50
pF1KB8 MSSYFVN-----PTFPGSLPSGQDSFLG-QLPLYQAGYDALRPFPASYGASSLPDKTY
::::.:: : :: : ..:: : : .: .. ::. : :
CCDS22 MVMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGG--------GAQGADFQPPGLY
10 20 30 40 50
60 70 80 90 100
pF1KB8 TSPCFYQQSNSVLACNRASYEYGASCFYSDKDLS----GASPSGSGKQRG-PGDYLHFSP
: : .: .:.: . : : :.: : . . ::. :
CCDS22 PRPDFGEQP------------FGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPP
60 70 80 90 100
110 120 130 140 150 160
pF1KB8 EQQYKP----DSSSGQGKALHDEGADRKYTSPVYPWMQRM--NSCAGAVYGSHGRRGRQT
: . : . :. : . :::::... :: :.. .:.: .
CCDS22 APPPAPLPGARAYSQSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTA
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB8 YTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQ
::: :.::::::::::::::::::::::..:::.:::::::::::::::::..:: :.
CCDS22 YTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKG
170 180 190 200 210 220
230
pF1KB8 PSGEDSEAKAGE
:. .: ...
CCDS22 RSSSSSSSSSCSSSVAPSQHLQPMAKDHHTDLTTL
230 240 250
>>CCDS11530.1 HOXB5 gene_id:3215|Hs108|chr17 (269 aa)
initn: 477 init1: 389 opt: 435 Z-score: 438.5 bits: 88.7 E(32554): 4.2e-18
Smith-Waterman score: 442; 42.1% identity (65.0% similar) in 197 aa overlap (42-216:66-255)
20 30 40 50 60
pF1KB8 GSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPC----FYQQSNSVLAC
.:: . .... .: : : ..: :
CCDS11 DPAAMHTGSYGYNYNGMDLSVNRSSASSSHFGAVGESSRAFPAPAQEPRFRQAASS---C
40 50 60 70 80 90
70 80 90 100 110
pF1KB8 NRASYEYGASCFYSDKDLSGASPSGSG---KQRGPGDYLHFS----------PE----QQ
. .: : . : .. : ::.::.:. . . .. .:. :: :
CCDS11 SLSSPE-SLPC--TNGDSHGAKPSASSPSDQATSASSSANFTEIDEASASSEPEEAASQL
100 110 120 130 140
120 130 140 150 160
pF1KB8 YKPDSSSGQGKALHDEGADRKYTSP-VYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLE
.:. . .: . . : . .: ..:::.... . . : :.:.: .::::::::
CCDS11 SSPSLARAQPEPMATSTAAPEGQTPQIFPWMRKLH-ISHDMTGPDGKRARTAYTRYQTLE
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB8 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA
::::::::::::::::::::.::::.:::::::::::::::::.:::
CCDS11 LEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSLATAGSAFQ
210 220 230 240 250 260
230
pF1KB8 KAGE
CCDS11 P
>>CCDS5408.1 HOXA7 gene_id:3204|Hs108|chr7 (230 aa)
initn: 462 init1: 389 opt: 428 Z-score: 432.6 bits: 87.3 E(32554): 8.9e-18
Smith-Waterman score: 441; 44.9% identity (60.2% similar) in 216 aa overlap (2-215:3-190)
10 20 30 40 50
pF1KB8 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQA-GYDALRPFPASYGASSLPDKTYTSPCFY
:::.:: : .. .: . : . : . . .. : ..:::.. . : : .:
CCDS54 MSSSYYVNALF-SKYTAGASLFQNAEPTSCSFAPNSQR---SGYGAGAGAFAS-TVPGLY
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 QQSNSVLACNRAS-YEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSS
. .. . :: : :: : : : .: : :: .. : :
CCDS54 NVNSPLYQSPFASGYGLGA-------DAYGNLPCASYDQNIPGLCSDLAKGACDKTD---
60 70 80 90 100
120 130 140 150 160 170
pF1KB8 GQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFN
.: ::: .:. .. .::::. : .:::::::::::::::::::::
CCDS54 -EG-ALHG-AAEANFR--IYPWMRSS--------GPDRKRGRQTYTRYQTLELEKEFHFN
110 120 130 140 150
180 190 200 210 220 230
pF1KB8 RYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE
::::::::::::.:::::::::::::::::::::::.:
CCDS54 RYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEGPTAAAAPEGAVPSAAATAA
160 170 180 190 200 210
CCDS54 ADKADEEDDDEEEEDEEE
220 230
>>CCDS8873.1 HOXC4 gene_id:3221|Hs108|chr12 (264 aa)
initn: 403 init1: 334 opt: 422 Z-score: 425.9 bits: 86.3 E(32554): 2.1e-17
Smith-Waterman score: 444; 38.8% identity (60.4% similar) in 240 aa overlap (1-224:8-229)
10 20 30 40
pF1KB8 MSSYFVNPTFPGSLPSGQDSFLGQL-PLY-----QAGYDALRP--FPASYGAS
:.: ...: :: .:.:.. . : : ..:.. . .:
CCDS88 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRP
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 SLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSG-SGKQRGPGDYLH
: :.. :. . .:: :. :. . .:. : :. :: . .:
CCDS88 SYPERQYSCTSLQGPGNS-----RGHGPAQAGHHHPEKSQSLCEPAPLSGASASP-----
70 80 90 100 110
110 120 130 140 150 160
pF1KB8 FSPEQQYKPDSSSGQGKALHDEGADRKYTSP-VYPWMQRMN-SCAGAVY-GSHGRRGRQT
:: : . : : : .: : .: :::::.... : .. : :.. .:.: .
CCDS88 -SPA----PPACS-QPAPDHPSSAASK--QPIVYPWMKKIHVSTVNPNYNGGEPKRSRTA
120 130 140 150 160
170 180 190 200 210
pF1KB8 YTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLIN---
::: :.::::::::.:::::::::::::..:::.:::::::::::::::::...: :
CCDS88 YTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKV
170 180 190 200 210 220
220 230
pF1KB8 -STQPSGEDSEAKAGE
:. :.:
CCDS88 RSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL
230 240 250 260
233 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 20:00:06 2016 done: Sat Nov 5 20:00:06 2016
Total Scan time: 2.050 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]