Result of FASTA (omim) for
pFN21AB7759
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7759, 447 aa
1>>>pF1KB7759 447 - 447 aa - 447 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2402+/-0.000294; mu= 15.2623+/- 0.019
mean_var=117.0786+/-23.933, 0's: 0 Z-trim(120.3): 413 B-trim: 1961 in 1/55
Lambda= 0.118532
statistics sampled from 35061 (35476) to 35061 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.764), E-opt: 0.2 (0.416), width: 16
Scan time: 8.990
The best scores are: opt bits E(85289)
XP_005252763 (OMIM: 602423) PREDICTED: oxysterols ( 447) 3026 528.0 1.9e-149
XP_005252762 (OMIM: 602423) PREDICTED: oxysterols ( 447) 3026 528.0 1.9e-149
XP_011518107 (OMIM: 602423) PREDICTED: oxysterols ( 447) 3026 528.0 1.9e-149
XP_006718176 (OMIM: 602423) PREDICTED: oxysterols ( 447) 3026 528.0 1.9e-149
XP_005252764 (OMIM: 602423) PREDICTED: oxysterols ( 447) 3026 528.0 1.9e-149
XP_006718175 (OMIM: 602423) PREDICTED: oxysterols ( 447) 3026 528.0 1.9e-149
NP_005684 (OMIM: 602423) oxysterols receptor LXR-a ( 447) 3026 528.0 1.9e-149
NP_001238864 (OMIM: 602423) oxysterols receptor LX ( 453) 2913 508.7 1.2e-143
NP_001238863 (OMIM: 602423) oxysterols receptor LX ( 453) 2913 508.7 1.2e-143
XP_016872547 (OMIM: 602423) PREDICTED: oxysterols ( 402) 2711 474.1 2.9e-133
XP_005252767 (OMIM: 602423) PREDICTED: oxysterols ( 402) 2711 474.1 2.9e-133
XP_005252766 (OMIM: 602423) PREDICTED: oxysterols ( 402) 2711 474.1 2.9e-133
XP_006718178 (OMIM: 602423) PREDICTED: oxysterols ( 402) 2711 474.1 2.9e-133
NP_001123574 (OMIM: 602423) oxysterols receptor LX ( 402) 2711 474.1 2.9e-133
XP_006718179 (OMIM: 602423) PREDICTED: oxysterols ( 402) 2711 474.1 2.9e-133
XP_016872545 (OMIM: 602423) PREDICTED: oxysterols ( 332) 2182 383.6 4.2e-106
XP_016872546 (OMIM: 602423) PREDICTED: oxysterols ( 323) 2174 382.2 1.1e-105
XP_011518109 (OMIM: 602423) PREDICTED: oxysterols ( 313) 1824 322.4 1.1e-87
XP_005252773 (OMIM: 602423) PREDICTED: oxysterols ( 313) 1824 322.4 1.1e-87
XP_005252772 (OMIM: 602423) PREDICTED: oxysterols ( 358) 1824 322.4 1.2e-87
NP_001123573 (OMIM: 602423) oxysterols receptor LX ( 387) 1646 292.0 1.8e-78
XP_005252770 (OMIM: 602423) PREDICTED: oxysterols ( 387) 1646 292.0 1.8e-78
XP_011518110 (OMIM: 602423) PREDICTED: oxysterols ( 235) 1534 272.7 7.4e-73
XP_011518108 (OMIM: 602423) PREDICTED: oxysterols ( 342) 1331 238.1 2.8e-62
NP_009052 (OMIM: 600380) oxysterols receptor LXR-b ( 461) 1233 221.4 3.8e-57
NP_001243576 (OMIM: 600380) oxysterols receptor LX ( 364) 1228 220.5 5.8e-57
XP_005252775 (OMIM: 602423) PREDICTED: oxysterols ( 253) 985 178.8 1.4e-44
NP_005114 (OMIM: 603826,617049) bile acid receptor ( 472) 915 167.1 9.1e-41
NP_001193921 (OMIM: 603826,617049) bile acid recep ( 482) 915 167.1 9.3e-41
NP_001193908 (OMIM: 603826,617049) bile acid recep ( 476) 897 164.0 7.8e-40
NP_001193906 (OMIM: 603826,617049) bile acid recep ( 476) 897 164.0 7.8e-40
XP_011537342 (OMIM: 603826,617049) PREDICTED: bile ( 476) 897 164.0 7.8e-40
NP_001193922 (OMIM: 603826,617049) bile acid recep ( 486) 897 164.0 7.9e-40
XP_016862602 (OMIM: 145650,188570,190160,274300) P ( 430) 747 138.3 3.8e-32
XP_011532355 (OMIM: 145650,188570,190160,274300) P ( 430) 747 138.3 3.8e-32
XP_016862603 (OMIM: 145650,188570,190160,274300) P ( 430) 747 138.3 3.8e-32
XP_016862604 (OMIM: 145650,188570,190160,274300) P ( 430) 747 138.3 3.8e-32
XP_016862601 (OMIM: 145650,188570,190160,274300) P ( 461) 747 138.3 4e-32
XP_011532353 (OMIM: 145650,188570,190160,274300) P ( 461) 747 138.3 4e-32
XP_016862597 (OMIM: 145650,188570,190160,274300) P ( 461) 747 138.3 4e-32
XP_016862598 (OMIM: 145650,188570,190160,274300) P ( 461) 747 138.3 4e-32
XP_016862600 (OMIM: 145650,188570,190160,274300) P ( 461) 747 138.3 4e-32
XP_011532349 (OMIM: 145650,188570,190160,274300) P ( 461) 747 138.3 4e-32
XP_011532350 (OMIM: 145650,188570,190160,274300) P ( 461) 747 138.3 4e-32
NP_000452 (OMIM: 145650,188570,190160,274300) thyr ( 461) 747 138.3 4e-32
XP_011532351 (OMIM: 145650,188570,190160,274300) P ( 461) 747 138.3 4e-32
NP_001239563 (OMIM: 145650,188570,190160,274300) t ( 461) 747 138.3 4e-32
XP_005265480 (OMIM: 145650,188570,190160,274300) P ( 461) 747 138.3 4e-32
NP_001121648 (OMIM: 145650,188570,190160,274300) t ( 461) 747 138.3 4e-32
XP_011532352 (OMIM: 145650,188570,190160,274300) P ( 461) 747 138.3 4e-32
>>XP_005252763 (OMIM: 602423) PREDICTED: oxysterols rece (447 aa)
initn: 3026 init1: 3026 opt: 3026 Z-score: 2804.1 bits: 528.0 E(85289): 1.9e-149
Smith-Waterman score: 3026; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447)
10 20 30 40 50 60
pF1KB7 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 AEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 FFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 APDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 AISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSV
370 380 390 400 410 420
430 440
pF1KB7 HSEQVFALRLQDKKLPPLLSEIWDVHE
:::::::::::::::::::::::::::
XP_005 HSEQVFALRLQDKKLPPLLSEIWDVHE
430 440
>>XP_005252762 (OMIM: 602423) PREDICTED: oxysterols rece (447 aa)
initn: 3026 init1: 3026 opt: 3026 Z-score: 2804.1 bits: 528.0 E(85289): 1.9e-149
Smith-Waterman score: 3026; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447)
10 20 30 40 50 60
pF1KB7 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 AEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 FFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 APDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 AISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSV
370 380 390 400 410 420
430 440
pF1KB7 HSEQVFALRLQDKKLPPLLSEIWDVHE
:::::::::::::::::::::::::::
XP_005 HSEQVFALRLQDKKLPPLLSEIWDVHE
430 440
>>XP_011518107 (OMIM: 602423) PREDICTED: oxysterols rece (447 aa)
initn: 3026 init1: 3026 opt: 3026 Z-score: 2804.1 bits: 528.0 E(85289): 1.9e-149
Smith-Waterman score: 3026; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447)
10 20 30 40 50 60
pF1KB7 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 AEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 FFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 APDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 AISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSV
370 380 390 400 410 420
430 440
pF1KB7 HSEQVFALRLQDKKLPPLLSEIWDVHE
:::::::::::::::::::::::::::
XP_011 HSEQVFALRLQDKKLPPLLSEIWDVHE
430 440
>>XP_006718176 (OMIM: 602423) PREDICTED: oxysterols rece (447 aa)
initn: 3026 init1: 3026 opt: 3026 Z-score: 2804.1 bits: 528.0 E(85289): 1.9e-149
Smith-Waterman score: 3026; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447)
10 20 30 40 50 60
pF1KB7 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 AEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 FFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 APDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 AISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSV
370 380 390 400 410 420
430 440
pF1KB7 HSEQVFALRLQDKKLPPLLSEIWDVHE
:::::::::::::::::::::::::::
XP_006 HSEQVFALRLQDKKLPPLLSEIWDVHE
430 440
>>XP_005252764 (OMIM: 602423) PREDICTED: oxysterols rece (447 aa)
initn: 3026 init1: 3026 opt: 3026 Z-score: 2804.1 bits: 528.0 E(85289): 1.9e-149
Smith-Waterman score: 3026; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447)
10 20 30 40 50 60
pF1KB7 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 AEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 FFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 APDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 AISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSV
370 380 390 400 410 420
430 440
pF1KB7 HSEQVFALRLQDKKLPPLLSEIWDVHE
:::::::::::::::::::::::::::
XP_005 HSEQVFALRLQDKKLPPLLSEIWDVHE
430 440
>>XP_006718175 (OMIM: 602423) PREDICTED: oxysterols rece (447 aa)
initn: 3026 init1: 3026 opt: 3026 Z-score: 2804.1 bits: 528.0 E(85289): 1.9e-149
Smith-Waterman score: 3026; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447)
10 20 30 40 50 60
pF1KB7 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 AEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 FFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 APDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 AISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSV
370 380 390 400 410 420
430 440
pF1KB7 HSEQVFALRLQDKKLPPLLSEIWDVHE
:::::::::::::::::::::::::::
XP_006 HSEQVFALRLQDKKLPPLLSEIWDVHE
430 440
>>NP_005684 (OMIM: 602423) oxysterols receptor LXR-alpha (447 aa)
initn: 3026 init1: 3026 opt: 3026 Z-score: 2804.1 bits: 528.0 E(85289): 1.9e-149
Smith-Waterman score: 3026; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447)
10 20 30 40 50 60
pF1KB7 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 AEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 FFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 APDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 APDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 AISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSV
370 380 390 400 410 420
430 440
pF1KB7 HSEQVFALRLQDKKLPPLLSEIWDVHE
:::::::::::::::::::::::::::
NP_005 HSEQVFALRLQDKKLPPLLSEIWDVHE
430 440
>>NP_001238864 (OMIM: 602423) oxysterols receptor LXR-al (453 aa)
initn: 2910 init1: 2910 opt: 2913 Z-score: 2699.6 bits: 508.7 E(85289): 1.2e-143
Smith-Waterman score: 2913; 99.1% identity (99.1% similar) in 438 aa overlap (13-447:16-453)
10 20 30 40 50
pF1KB7 MSLWLGAPVPDIPPD---SAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTA
:: :::::::::::::::::::::::::::::::::::::::
NP_001 MQQTSWNPLGGTCKQPPGRTHSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 GVGLEAAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVGLEAAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 CEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 RLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 VTPWPMAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTPWPMAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 IEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 EFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSL
370 380 390 400 410 420
420 430 440
pF1KB7 RTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
:::::::::::::::::::::::::::::::::
NP_001 RTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
430 440 450
>>NP_001238863 (OMIM: 602423) oxysterols receptor LXR-al (453 aa)
initn: 2910 init1: 2910 opt: 2913 Z-score: 2699.6 bits: 508.7 E(85289): 1.2e-143
Smith-Waterman score: 2913; 99.1% identity (99.1% similar) in 438 aa overlap (13-447:16-453)
10 20 30 40 50
pF1KB7 MSLWLGAPVPDIPPD---SAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTA
:: :::::::::::::::::::::::::::::::::::::::
NP_001 MQQTSWNPLGGTCKQPPGRTHSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 GVGLEAAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVGLEAAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 CEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 RLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 VTPWPMAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTPWPMAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 IEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 EFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSL
370 380 390 400 410 420
420 430 440
pF1KB7 RTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
:::::::::::::::::::::::::::::::::
NP_001 RTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
430 440 450
>>XP_016872547 (OMIM: 602423) PREDICTED: oxysterols rece (402 aa)
initn: 2711 init1: 2711 opt: 2711 Z-score: 2513.6 bits: 474.1 E(85289): 2.9e-133
Smith-Waterman score: 2711; 100.0% identity (100.0% similar) in 402 aa overlap (46-447:1-402)
20 30 40 50 60 70
pF1KB7 SAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEAAEPTALLTRAEPPSE
::::::::::::::::::::::::::::::
XP_016 MPHSAGGTAGVGLEAAEPTALLTRAEPPSE
10 20 30
80 90 100 110 120 130
pF1KB7 PTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICH
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB7 SGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPR
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB7 ASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB7 HFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITF
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB7 LKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQ
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB7 LQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKL
340 350 360 370 380 390
440
pF1KB7 PPLLSEIWDVHE
::::::::::::
XP_016 PPLLSEIWDVHE
400
447 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 22:11:34 2016 done: Fri Nov 4 22:11:35 2016
Total Scan time: 8.990 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]