Result of FASTA (omim) for
pFN21AA0705
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0705, 1441 aa
1>>>pF1KA0705 1441 - 1441 aa - 1441 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.1498+/-0.000466; mu= -6.0264+/- 0.029
mean_var=528.6381+/-112.069, 0's: 0 Z-trim(122.4): 107 B-trim: 1104 in 1/60
Lambda= 0.055782
statistics sampled from 40292 (40427) to 40292 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.759), E-opt: 0.2 (0.474), width: 16
Scan time: 20.940
The best scores are: opt bits E(85289)
NP_001288057 (OMIM: 606382) membrane-associated gu (1441) 9878 811.2 0
XP_016868335 (OMIM: 606382) PREDICTED: membrane-as (1483) 8363 689.3 5.7e-197
XP_016868332 (OMIM: 606382) PREDICTED: membrane-as (1526) 5666 472.3 1.3e-131
NP_036433 (OMIM: 606382) membrane-associated guany (1455) 5492 458.3 2e-127
XP_011515020 (OMIM: 606382) PREDICTED: membrane-as (1497) 5411 451.7 1.9e-125
XP_016868334 (OMIM: 606382) PREDICTED: membrane-as (1495) 5410 451.7 2e-125
XP_016868333 (OMIM: 606382) PREDICTED: membrane-as (1498) 4722 396.3 9.3e-109
XP_016868337 (OMIM: 606382) PREDICTED: membrane-as (1334) 4323 364.1 4e-99
XP_016868338 (OMIM: 606382) PREDICTED: membrane-as (1332) 4322 364.1 4.2e-99
XP_016868331 (OMIM: 606382) PREDICTED: membrane-as (1538) 3213 274.9 3.4e-72
XP_011515030 (OMIM: 606382) PREDICTED: membrane-as (1106) 3207 274.2 3.8e-72
XP_011515028 (OMIM: 606382) PREDICTED: membrane-as (1149) 3207 274.3 3.9e-72
XP_011515021 (OMIM: 606382) PREDICTED: membrane-as (1377) 3207 274.3 4.4e-72
XP_011515022 (OMIM: 606382) PREDICTED: membrane-as (1377) 3207 274.3 4.4e-72
XP_016868336 (OMIM: 606382) PREDICTED: membrane-as (1377) 3207 274.3 4.4e-72
XP_016868330 (OMIM: 606382) PREDICTED: membrane-as (1539) 3207 274.4 4.8e-72
XP_016868329 (OMIM: 606382) PREDICTED: membrane-as (1540) 3207 274.4 4.8e-72
XP_016868340 (OMIM: 606382) PREDICTED: membrane-as (1298) 3187 272.7 1.3e-71
XP_016868339 (OMIM: 606382) PREDICTED: membrane-as (1326) 3186 272.6 1.4e-71
XP_016868341 (OMIM: 606382) PREDICTED: membrane-as (1284) 3181 272.2 1.8e-71
XP_011532538 (OMIM: 602625) PREDICTED: membrane-as (1480) 1741 156.4 1.5e-36
XP_006713473 (OMIM: 602625) PREDICTED: membrane-as (1479) 1722 154.9 4.4e-36
XP_005265625 (OMIM: 602625) PREDICTED: membrane-as (1478) 1716 154.4 6.1e-36
XP_016862997 (OMIM: 602625) PREDICTED: membrane-as (1168) 1690 152.2 2.2e-35
XP_016862996 (OMIM: 602625) PREDICTED: membrane-as (1224) 1690 152.2 2.3e-35
XP_005265623 (OMIM: 602625) PREDICTED: membrane-as (1479) 1687 152.0 3.1e-35
XP_016862995 (OMIM: 602625) PREDICTED: membrane-as (1276) 1594 144.5 5e-33
XP_005265622 (OMIM: 602625) PREDICTED: membrane-as (1481) 1475 135.0 4.2e-30
NP_004733 (OMIM: 602625) membrane-associated guany (1256) 1325 122.8 1.6e-26
NP_056335 (OMIM: 602625) membrane-associated guany (1287) 1325 122.8 1.7e-26
XP_005265631 (OMIM: 602625) PREDICTED: membrane-as (1288) 1325 122.8 1.7e-26
XP_005265628 (OMIM: 602625) PREDICTED: membrane-as (1395) 1325 122.9 1.7e-26
NP_001028229 (OMIM: 602625) membrane-associated gu (1462) 1325 122.9 1.8e-26
XP_006713475 (OMIM: 602625) PREDICTED: membrane-as (1463) 1325 122.9 1.8e-26
XP_016862987 (OMIM: 602625) PREDICTED: membrane-as (1490) 1325 122.9 1.8e-26
XP_005265621 (OMIM: 602625) PREDICTED: membrane-as (1491) 1325 122.9 1.8e-26
XP_016862994 (OMIM: 602625) PREDICTED: membrane-as (1288) 1320 122.4 2.2e-26
XP_016862991 (OMIM: 602625) PREDICTED: membrane-as (1289) 1320 122.4 2.2e-26
XP_016862993 (OMIM: 602625) PREDICTED: membrane-as (1288) 1319 122.4 2.3e-26
XP_016862990 (OMIM: 602625) PREDICTED: membrane-as (1452) 1320 122.5 2.4e-26
XP_016862986 (OMIM: 602625) PREDICTED: membrane-as (1491) 1320 122.5 2.4e-26
XP_006713472 (OMIM: 602625) PREDICTED: membrane-as (1492) 1320 122.5 2.4e-26
XP_006713471 (OMIM: 602625) PREDICTED: membrane-as (1492) 1319 122.4 2.6e-26
XP_016862989 (OMIM: 602625) PREDICTED: membrane-as (1455) 1231 115.3 3.4e-24
XP_016862988 (OMIM: 602625) PREDICTED: membrane-as (1458) 1231 115.3 3.4e-24
XP_016862992 (OMIM: 602625) PREDICTED: membrane-as (1289) 1125 106.8 1.2e-21
XP_006713477 (OMIM: 602625) PREDICTED: membrane-as (1290) 1125 106.8 1.2e-21
XP_005265627 (OMIM: 602625) PREDICTED: membrane-as (1425) 1125 106.8 1.2e-21
XP_006713474 (OMIM: 602625) PREDICTED: membrane-as (1465) 1125 106.8 1.3e-21
XP_005265620 (OMIM: 602625) PREDICTED: membrane-as (1492) 1125 106.8 1.3e-21
>>NP_001288057 (OMIM: 606382) membrane-associated guanyl (1441 aa)
initn: 9878 init1: 9878 opt: 9878 Z-score: 4316.3 bits: 811.2 E(85289): 0
Smith-Waterman score: 9878; 100.0% identity (100.0% similar) in 1441 aa overlap (1-1441:1-1441)
10 20 30 40 50 60
pF1KA0 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFREKPLFTRDASQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFREKPLFTRDASQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KGTFLSTTLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGTFLSTTLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 VLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RHNYETYLEYISRTSQSVPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHNYETYLEYISRTSQSVPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 AELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 EVVDILKDCPIGSETSLIIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVVDILKDCPIGSETSLIIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYESRRPDYKELDVHLRRMESGFGFRILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYESRRPDYKELDVHLRRMESGFGFRILG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 GDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 NLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 SLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 ILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQSPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQSPLA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 QQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 PLDYRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLDYRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 KGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA0 KSGGRRVRLLLKRGTGQVPEYDEPAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSGGRRVRLLLKRGTGQVPEYDEPAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA0 DPSHQISPGPTWDIKREHDVRKPKELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPSHQISPGPTWDIKREHDVRKPKELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA0 QGRPEAGRPASEARAPGLAAADAADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGRPEAGRPASEARAPGLAAADAADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGG
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA0 GGSGALEAEGRAGARAGPRPGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGSGALEAEGRAGARAGPRPGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAAS
1390 1400 1410 1420 1430 1440
pF1KA0 R
:
NP_001 R
>>XP_016868335 (OMIM: 606382) PREDICTED: membrane-associ (1483 aa)
initn: 9864 init1: 8337 opt: 8363 Z-score: 3657.2 bits: 689.3 E(85289): 5.7e-197
Smith-Waterman score: 9723; 97.1% identity (97.1% similar) in 1473 aa overlap (1-1431:1-1473)
10 20 30 40 50 60
pF1KA0 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFREKPLFTRDASQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFREKPLFTRDASQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KGTFLSTTLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGTFLSTTLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 VLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RHNYETYLEYISRTSQSVPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHNYETYLEYISRTSQSVPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 AELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 EVVDILKDCPIGSETSLIIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVVDILKDCPIGSETSLIIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 PALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYESRRPDYKELDVHLRRMESGFGFRILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYESRRPDYKELDVHLRRMESGFGFRILG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 GDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 NLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 SLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 ILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQSPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQSPLA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 QQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA0 PLDYRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLDYRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGA
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA0 KGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELI
1150 1160 1170 1180 1190 1200
1210 1220
pF1KA0 KSGGRRVRLLLKRGTGQVPEY---------------------------------------
:::::::::::::::::::::
XP_016 KSGGRRVRLLLKRGTGQVPEYGMVPSSLSMCMKSDKHGSPYFYLLGHPKDTERSKLARTD
1210 1220 1230 1240 1250 1260
1230 1240 1250 1260 1270
pF1KA0 ---DEPAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPSDPSHQISPGPTWDIKREH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRKDEPAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPSDPSHQISPGPTWDIKREH
1270 1280 1290 1300 1310 1320
1280 1290 1300 1310 1320 1330
pF1KA0 DVRKPKELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGGQGRPEAGRPASEARAPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVRKPKELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGGQGRPEAGRPASEARAPGL
1330 1340 1350 1360 1370 1380
1340 1350 1360 1370 1380 1390
pF1KA0 AAADAADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGSGALEAEGRAGARAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAADAADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGSGALEAEGRAGARAGP
1390 1400 1410 1420 1430 1440
1400 1410 1420 1430 1440
pF1KA0 RPGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAASR
:::::::::::::::::::::::::::::::::
XP_016 RPGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAASR
1450 1460 1470 1480
>>XP_016868332 (OMIM: 606382) PREDICTED: membrane-associ (1526 aa)
initn: 9850 init1: 5563 opt: 5666 Z-score: 2484.0 bits: 472.3 E(85289): 1.3e-131
Smith-Waterman score: 9551; 94.4% identity (94.4% similar) in 1505 aa overlap (12-1431:12-1516)
10 20 30 40 50 60
pF1KA0 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
310 320 330 340 350 360
370 380 390 400
pF1KA0 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFR------------
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFRVDSSSWTLPRPK
370 380 390 400 410 420
410 420 430
pF1KA0 -------------------------------EKPLFTRDASQLKGTFLSTTLKKSNMGFG
:::::::::::::::::::::::::::::
XP_016 SIRPRAAPERSRSVNDLSYYQRDPAGRPWLFEKPLFTRDASQLKGTFLSTTLKKSNMGFG
430 440 450 460 470 480
440 450 460 470 480 490
pF1KA0 FTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVP
490 500 510 520 530 540
500 510 520 530 540 550
pF1KA0 IGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNGRHNYETYLEYISRTSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNGRHNYETYLEYISRTSQS
550 560 570 580 590 600
560 570 580 590 600 610
pF1KA0 VPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQGFGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQGFGF
610 620 630 640 650 660
620 630 640 650 660 670
pF1KA0 TIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPIGSETSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPIGSETSL
670 680 690 700 710 720
680 690 700 710 720 730
pF1KA0 IIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFPPALHRSSFPDSTEAFDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFPPALHRSSFPDSTEAFDP
730 740 750 760 770 780
740 750 760 770 780 790
pF1KA0 RKPDPYELYEKSRAIYESRRPDYKELDVHLRRMESGFGFRILGGDEPGQPILIGAVIAMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKPDPYELYEKSRAIYESRRPDYKELDVHLRRMESGFGFRILGGDEPGQPILIGAVIAMG
790 800 810 820 830 840
800 810 820 830 840 850
pF1KA0 SADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPE
850 860 870 880 890 900
860 870 880 890 900 910
pF1KA0 NGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGF
910 920 930 940 950 960
920 930 940 950 960 970
pF1KA0 GFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADI
970 980 990 1000 1010 1020
980 990 1000 1010 1020 1030
pF1KA0 VKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQSPLAQQSPLAQPSPATPNSPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQSPLAQQSPLAQPSPATPNSPI
1030 1040 1050 1060 1070 1080
1040 1050 1060 1070 1080 1090
pF1KA0 AQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGGDYQQPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGGDYQQPPP
1090 1100 1110 1120 1130 1140
1100 1110 1120 1130 1140 1150
pF1KA0 LDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGAKGFGFSIRGGREYKMDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGAKGFGFSIRGGREYKMDL
1150 1160 1170 1180 1190 1200
1160 1170 1180 1190 1200 1210
pF1KA0 YVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVRLLLKRGTGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVRLLLKRGTGQ
1210 1220 1230 1240 1250 1260
1220 1230
pF1KA0 VPEY------------------------------------------DEPAPWSSPAAAAP
:::: ::::::::::::::
XP_016 VPEYGMVPSSLSMCMKSDKHGSPYFYLLGHPKDTERSKLARTDNRKDEPAPWSSPAAAAP
1270 1280 1290 1300 1310 1320
1240 1250 1260 1270 1280 1290
pF1KA0 GLPEVGVSLDDGLAPFSPSHPAPPSDPSHQISPGPTWDIKREHDVRKPKELSACGQKKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLPEVGVSLDDGLAPFSPSHPAPPSDPSHQISPGPTWDIKREHDVRKPKELSACGQKKQR
1330 1340 1350 1360 1370 1380
1300 1310 1320 1330 1340 1350
pF1KA0 LGEQRERSASPQRAARPRLEEAPGGQGRPEAGRPASEARAPGLAAADAADAARAGGKEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGEQRERSASPQRAARPRLEEAPGGQGRPEAGRPASEARAPGLAAADAADAARAGGKEAP
1390 1400 1410 1420 1430 1440
1360 1370 1380 1390 1400 1410
pF1KA0 RAAAGSELCRREGPGAAPAFAGPGGGGSGALEAEGRAGARAGPRPGPRPPGGAPARKAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAAAGSELCRREGPGAAPAFAGPGGGGSGALEAEGRAGARAGPRPGPRPPGGAPARKAAV
1450 1460 1470 1480 1490 1500
1420 1430 1440
pF1KA0 APGPWKVPGSDKLPSVLKPGASAASR
::::::::::::::::
XP_016 APGPWKVPGSDKLPSVLKPGASAASR
1510 1520
>>NP_036433 (OMIM: 606382) membrane-associated guanylate (1455 aa)
initn: 5312 init1: 5161 opt: 5492 Z-score: 2408.6 bits: 458.3 E(85289): 2e-127
Smith-Waterman score: 9834; 99.0% identity (99.0% similar) in 1455 aa overlap (1-1441:1-1455)
10 20 30 40 50 60
pF1KA0 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFREKPLFTRDASQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFREKPLFTRDASQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KGTFLSTTLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KGTFLSTTLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 VLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RHNYETYLEYISRTSQSVPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RHNYETYLEYISRTSQSVPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 AELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 EVVDILKDCPIGSETSLIIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EVVDILKDCPIGSETSLIIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFP
670 680 690 700 710 720
730 740 750 760
pF1KA0 PALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYESRR--------------PDYKELDVH
::::::::::::::::::::::::::::::::::::. :::::::::
NP_036 PALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVH
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA0 LRRMESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LRRMESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRY
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA0 VIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAA
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA0 PSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDG
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA0 SPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPS
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA0 SEKQSPMAQQSPLAQQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SEKQSPMAQQSPLAQQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVK
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA0 PDIRQPPFTDYRQPPLDYRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PDIRQPPFTDYRQPPLDYRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQP
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KA0 QDFDYFTVDMEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QDFDYFTVDMEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGE
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KA0 STRDMTHARAIELIKSGGRRVRLLLKRGTGQVPEYDEPAPWSSPAAAAPGLPEVGVSLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 STRDMTHARAIELIKSGGRRVRLLLKRGTGQVPEYDEPAPWSSPAAAAPGLPEVGVSLDD
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KA0 GLAPFSPSHPAPPSDPSHQISPGPTWDIKREHDVRKPKELSACGQKKQRLGEQRERSASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GLAPFSPSHPAPPSDPSHQISPGPTWDIKREHDVRKPKELSACGQKKQRLGEQRERSASP
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KA0 QRAARPRLEEAPGGQGRPEAGRPASEARAPGLAAADAADAARAGGKEAPRAAAGSELCRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QRAARPRLEEAPGGQGRPEAGRPASEARAPGLAAADAADAARAGGKEAPRAAAGSELCRR
1330 1340 1350 1360 1370 1380
1370 1380 1390 1400 1410 1420
pF1KA0 EGPGAAPAFAGPGGGGSGALEAEGRAGARAGPRPGPRPPGGAPARKAAVAPGPWKVPGSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EGPGAAPAFAGPGGGGSGALEAEGRAGARAGPRPGPRPPGGAPARKAAVAPGPWKVPGSD
1390 1400 1410 1420 1430 1440
1430 1440
pF1KA0 KLPSVLKPGASAASR
:::::::::::::::
NP_036 KLPSVLKPGASAASR
1450
>>XP_011515020 (OMIM: 606382) PREDICTED: membrane-associ (1497 aa)
initn: 6839 init1: 5161 opt: 5411 Z-score: 2373.2 bits: 451.7 E(85289): 1.9e-125
Smith-Waterman score: 9573; 96.1% identity (96.2% similar) in 1473 aa overlap (1-1417:1-1473)
10 20 30 40 50 60
pF1KA0 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFREKPLFTRDASQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFREKPLFTRDASQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KGTFLSTTLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGTFLSTTLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 VLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RHNYETYLEYISRTSQSVPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHNYETYLEYISRTSQSVPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 AELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 EVVDILKDCPIGSETSLIIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVVDILKDCPIGSETSLIIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFP
670 680 690 700 710 720
730 740 750 760
pF1KA0 PALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYESRR--------------PDYKELDVH
::::::::::::::::::::::::::::::::::::. :::::::::
XP_011 PALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVH
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA0 LRRMESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRMESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRY
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA0 VIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAA
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA0 PSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDG
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA0 SPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPS
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA0 SEKQSPMAQQSPLAQQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEKQSPMAQQSPLAQQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVK
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA0 PDIRQPPFTDYRQPPLDYRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDIRQPPFTDYRQPPLDYRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQP
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KA0 QDFDYFTVDMEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDFDYFTVDMEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGE
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220
pF1KA0 STRDMTHARAIELIKSGGRRVRLLLKRGTGQVPEY-------------------------
:::::::::::::::::::::::::::::::::::
XP_011 STRDMTHARAIELIKSGGRRVRLLLKRGTGQVPEYGMVPSSLSMCMKSDKHGSPYFYLLG
1210 1220 1230 1240 1250 1260
1230 1240 1250 1260
pF1KA0 -----------------DEPAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPSDPSH
:::::::::::::::::::::::::::::::::::::::::::
XP_011 HPKDTERSKLARTDNRKDEPAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPSDPSH
1270 1280 1290 1300 1310 1320
1270 1280 1290 1300 1310 1320
pF1KA0 QISPGPTWDIKREHDVRKPKELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGGQGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QISPGPTWDIKREHDVRKPKELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGGQGRP
1330 1340 1350 1360 1370 1380
1330 1340 1350 1360 1370 1380
pF1KA0 EAGRPASEARAPGLAAADAADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAGRPASEARAPGLAAADAADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGSG
1390 1400 1410 1420 1430 1440
1390 1400 1410 1420 1430 1440
pF1KA0 ALEAEGRAGARAGPRPGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAASR
:::::::::::::::::::::::::::::::::
XP_011 ALEAEGRAGARAGPRPGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAASR
1450 1460 1470 1480 1490
>>XP_016868334 (OMIM: 606382) PREDICTED: membrane-associ (1495 aa)
initn: 6834 init1: 5156 opt: 5410 Z-score: 2372.8 bits: 451.7 E(85289): 2e-125
Smith-Waterman score: 9583; 96.2% identity (96.2% similar) in 1473 aa overlap (1-1419:1-1473)
10 20 30 40 50 60
pF1KA0 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFREKPLFTRDASQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFREKPLFTRDASQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 KGTFLSTTLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGTFLSTTLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 VLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 RHNYETYLEYISRTSQSVPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHNYETYLEYISRTSQSVPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 AELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 EVVDILKDCPIGSETSLIIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVVDILKDCPIGSETSLIIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFP
670 680 690 700 710 720
730 740 750 760
pF1KA0 PALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYE------------SRRPDYKELDVHLR
:::::::::::::::::::::::::::::::::: : :::::::::::
XP_016 PALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYEKQVPPRTSFRMDSSGPDYKELDVHLR
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA0 RMESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVI
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA0 DLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPS
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA0 SNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSP
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA0 ADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSE
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA0 KQSPMAQQSPLAQQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQSPMAQQSPLAQQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPD
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA0 IRQPPFTDYRQPPLDYRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRQPPFTDYRQPPLDYRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQD
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KA0 FDYFTVDMEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGEST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDYFTVDMEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGEST
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220
pF1KA0 RDMTHARAIELIKSGGRRVRLLLKRGTGQVPEY---------------------------
:::::::::::::::::::::::::::::::::
XP_016 RDMTHARAIELIKSGGRRVRLLLKRGTGQVPEYGMVPSSLSMCMKSDKHGSPYFYLLGHP
1210 1220 1230 1240 1250 1260
1230 1240 1250 1260
pF1KA0 ---------------DEPAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPSDPSHQI
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDTERSKLARTDNRKDEPAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPSDPSHQI
1270 1280 1290 1300 1310 1320
1270 1280 1290 1300 1310 1320
pF1KA0 SPGPTWDIKREHDVRKPKELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGGQGRPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPGPTWDIKREHDVRKPKELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGGQGRPEA
1330 1340 1350 1360 1370 1380
1330 1340 1350 1360 1370 1380
pF1KA0 GRPASEARAPGLAAADAADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGSGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRPASEARAPGLAAADAADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGSGAL
1390 1400 1410 1420 1430 1440
1390 1400 1410 1420 1430 1440
pF1KA0 EAEGRAGARAGPRPGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAASR
:::::::::::::::::::::::::::::::::
XP_016 EAEGRAGARAGPRPGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAASR
1450 1460 1470 1480 1490
>>XP_016868333 (OMIM: 606382) PREDICTED: membrane-associ (1498 aa)
initn: 7474 init1: 4714 opt: 4722 Z-score: 2073.5 bits: 396.3 E(85289): 9.3e-109
Smith-Waterman score: 9572; 96.1% identity (96.1% similar) in 1473 aa overlap (26-1441:26-1498)
10 20 30 40 50 60
pF1KA0 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
:::::::::::::::::::::::::::::::::::
XP_016 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
310 320 330 340 350 360
370 380 390 400
pF1KA0 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFR------------
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFRVDSSSWTLPRPK
370 380 390 400 410 420
410 420 430
pF1KA0 -------------------------------EKPLFTRDASQLKGTFLSTTLKKSNMGFG
:::::::::::::::::::::::::::::
XP_016 SIRPRAAPERSRSVNDLSYYQRDPAGRPWLFEKPLFTRDASQLKGTFLSTTLKKSNMGFG
430 440 450 460 470 480
440 450 460 470 480 490
pF1KA0 FTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVP
490 500 510 520 530 540
500 510 520 530 540 550
pF1KA0 IGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNGRHNYETYLEYISRTSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNGRHNYETYLEYISRTSQS
550 560 570 580 590 600
560 570 580 590 600 610
pF1KA0 VPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQGFGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQGFGF
610 620 630 640 650 660
620 630 640 650 660 670
pF1KA0 TIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPIGSETSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPIGSETSL
670 680 690 700 710 720
680 690 700 710 720 730
pF1KA0 IIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFPPALHRSSFPDSTEAFDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFPPALHRSSFPDSTEAFDP
730 740 750 760 770 780
740 750 760 770 780
pF1KA0 RKPDPYELYEKSRAIYESRR--------------PDYKELDVHLRRMESGFGFRILGGDE
:::::::::::::::::::. ::::::::::::::::::::::::::
XP_016 RKPDPYELYEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGGDE
790 800 810 820 830 840
790 800 810 820 830 840
pF1KA0 PGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLT
850 860 870 880 890 900
850 860 870 880 890 900
pF1KA0 VRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQ
910 920 930 940 950 960
910 920 930 940 950 960
pF1KA0 TSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILA
970 980 990 1000 1010 1020
970 980 990 1000 1010 1020
pF1KA0 VNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQSPLAQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQSPLAQQS
1030 1040 1050 1060 1070 1080
1030 1040 1050 1060 1070 1080
pF1KA0 PLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLD
1090 1100 1110 1120 1130 1140
1090 1100 1110 1120 1130 1140
pF1KA0 YRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGAKGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGAKGF
1150 1160 1170 1180 1190 1200
1150 1160 1170 1180 1190 1200
pF1KA0 GFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSG
1210 1220 1230 1240 1250 1260
1210 1220 1230 1240 1250 1260
pF1KA0 GRRVRLLLKRGTGQVPEYDEPAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPSDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRRVRLLLKRGTGQVPEYDEPAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPSDPS
1270 1280 1290 1300 1310 1320
1270 1280 1290 1300 1310 1320
pF1KA0 HQISPGPTWDIKREHDVRKPKELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGGQGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQISPGPTWDIKREHDVRKPKELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGGQGR
1330 1340 1350 1360 1370 1380
1330 1340 1350 1360 1370 1380
pF1KA0 PEAGRPASEARAPGLAAADAADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEAGRPASEARAPGLAAADAADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGS
1390 1400 1410 1420 1430 1440
1390 1400 1410 1420 1430 1440
pF1KA0 GALEAEGRAGARAGPRPGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAASR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GALEAEGRAGARAGPRPGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAASR
1450 1460 1470 1480 1490
>>XP_016868337 (OMIM: 606382) PREDICTED: membrane-associ (1334 aa)
initn: 5751 init1: 4073 opt: 4323 Z-score: 1900.6 bits: 364.1 E(85289): 4e-99
Smith-Waterman score: 8485; 95.6% identity (95.7% similar) in 1310 aa overlap (164-1417:1-1310)
140 150 160 170 180 190
pF1KA0 YLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYEDNYYGTPKPPAEPA
::::::::::::::::::::::::::::::
XP_016 MELEKSGALLESGTYEDNYYGTPKPPAEPA
10 20 30
200 210 220 230 240 250
pF1KA0 PLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERPVVNGNGVVVTPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERPVVNGNGVVVTPES
40 50 60 70 80 90
260 270 280 290 300 310
pF1KA0 SEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEEPDPLPDNWEMAYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEEPDPLPDNWEMAYT
100 110 120 130 140 150
320 330 340 350 360 370
pF1KA0 EKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDPIYGTYYVDHINRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDPIYGTYYVDHINRR
160 170 180 190 200 210
380 390 400 410 420 430
pF1KA0 TQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFREKPLFTRDASQLKGTFLSTTLKKSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFREKPLFTRDASQLKGTFLSTTLKKSN
220 230 240 250 260 270
440 450 460 470 480 490
pF1KA0 MGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLF
280 290 300 310 320 330
500 510 520 530 540 550
pF1KA0 QSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNGRHNYETYLEYISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNGRHNYETYLEYISR
340 350 360 370 380 390
560 570 580 590 600 610
pF1KA0 TSQSVPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSQSVPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQ
400 410 420 430 440 450
620 630 640 650 660 670
pF1KA0 GFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPIGS
460 470 480 490 500 510
680 690 700 710 720 730
pF1KA0 ETSLIIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFPPALHRSSFPDSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETSLIIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFPPALHRSSFPDSTE
520 530 540 550 560 570
740 750 760 770
pF1KA0 AFDPRKPDPYELYEKSRAIYESRR--------------PDYKELDVHLRRMESGFGFRIL
:::::::::::::::::::::::. ::::::::::::::::::::::
XP_016 AFDPRKPDPYELYEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRIL
580 590 600 610 620 630
780 790 800 810 820 830
pF1KA0 GGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQ
640 650 660 670 680 690
840 850 860 870 880 890
pF1KA0 VNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFAS
700 710 720 730 740 750
900 910 920 930 940 950
pF1KA0 HSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSLQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGD
760 770 780 790 800 810
960 970 980 990 1000 1010
pF1KA0 RILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQSPL
820 830 840 850 860 870
1020 1030 1040 1050 1060 1070
pF1KA0 AQQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQQSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQ
880 890 900 910 920 930
1080 1090 1100 1110 1120 1130
pF1KA0 PPLDYRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPLDYRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKG
940 950 960 970 980 990
1140 1150 1160 1170 1180 1190
pF1KA0 AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIEL
1000 1010 1020 1030 1040 1050
1200 1210 1220
pF1KA0 IKSGGRRVRLLLKRGTGQVPEY--------------------------------------
::::::::::::::::::::::
XP_016 IKSGGRRVRLLLKRGTGQVPEYGMVPSSLSMCMKSDKHGSPYFYLLGHPKDTERSKLART
1060 1070 1080 1090 1100 1110
1230 1240 1250 1260 1270
pF1KA0 ----DEPAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPSDPSHQISPGPTWDIKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNRKDEPAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPSDPSHQISPGPTWDIKRE
1120 1130 1140 1150 1160 1170
1280 1290 1300 1310 1320 1330
pF1KA0 HDVRKPKELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGGQGRPEAGRPASEARAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDVRKPKELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGGQGRPEAGRPASEARAPG
1180 1190 1200 1210 1220 1230
1340 1350 1360 1370 1380 1390
pF1KA0 LAAADAADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGSGALEAEGRAGARAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAAADAADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGSGALEAEGRAGARAG
1240 1250 1260 1270 1280 1290
1400 1410 1420 1430 1440
pF1KA0 PRPGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAASR
::::::::::::::::::::
XP_016 PRPGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAASR
1300 1310 1320 1330
>>XP_016868338 (OMIM: 606382) PREDICTED: membrane-associ (1332 aa)
initn: 5746 init1: 4068 opt: 4322 Z-score: 1900.2 bits: 364.1 E(85289): 4.2e-99
Smith-Waterman score: 8495; 95.7% identity (95.7% similar) in 1310 aa overlap (164-1419:1-1310)
140 150 160 170 180 190
pF1KA0 YLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYEDNYYGTPKPPAEPA
::::::::::::::::::::::::::::::
XP_016 MELEKSGALLESGTYEDNYYGTPKPPAEPA
10 20 30
200 210 220 230 240 250
pF1KA0 PLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERPVVNGNGVVVTPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERPVVNGNGVVVTPES
40 50 60 70 80 90
260 270 280 290 300 310
pF1KA0 SEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEEPDPLPDNWEMAYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEEPDPLPDNWEMAYT
100 110 120 130 140 150
320 330 340 350 360 370
pF1KA0 EKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDPIYGTYYVDHINRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDPIYGTYYVDHINRR
160 170 180 190 200 210
380 390 400 410 420 430
pF1KA0 TQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFREKPLFTRDASQLKGTFLSTTLKKSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFREKPLFTRDASQLKGTFLSTTLKKSN
220 230 240 250 260 270
440 450 460 470 480 490
pF1KA0 MGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLF
280 290 300 310 320 330
500 510 520 530 540 550
pF1KA0 QSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNGRHNYETYLEYISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNGRHNYETYLEYISR
340 350 360 370 380 390
560 570 580 590 600 610
pF1KA0 TSQSVPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSQSVPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQ
400 410 420 430 440 450
620 630 640 650 660 670
pF1KA0 GFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPIGS
460 470 480 490 500 510
680 690 700 710 720 730
pF1KA0 ETSLIIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFPPALHRSSFPDSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETSLIIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFPPALHRSSFPDSTE
520 530 540 550 560 570
740 750 760 770 780
pF1KA0 AFDPRKPDPYELYEKSRAIYE------------SRRPDYKELDVHLRRMESGFGFRILGG
::::::::::::::::::::: : ::::::::::::::::::::::::
XP_016 AFDPRKPDPYELYEKSRAIYEKQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGG
580 590 600 610 620 630
790 800 810 820 830 840
pF1KA0 DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVN
640 650 660 670 680 690
850 860 870 880 890 900
pF1KA0 LTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHS
700 710 720 730 740 750
910 920 930 940 950 960
pF1KA0 LQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRI
760 770 780 790 800 810
970 980 990 1000 1010 1020
pF1KA0 LAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQSPLAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQSPLAQ
820 830 840 850 860 870
1030 1040 1050 1060 1070 1080
pF1KA0 QSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSPLAQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPP
880 890 900 910 920 930
1090 1100 1110 1120 1130 1140
pF1KA0 LDYRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDYRQPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGAK
940 950 960 970 980 990
1150 1160 1170 1180 1190 1200
pF1KA0 GFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIK
1000 1010 1020 1030 1040 1050
1210 1220
pF1KA0 SGGRRVRLLLKRGTGQVPEY----------------------------------------
::::::::::::::::::::
XP_016 SGGRRVRLLLKRGTGQVPEYGMVPSSLSMCMKSDKHGSPYFYLLGHPKDTERSKLARTDN
1060 1070 1080 1090 1100 1110
1230 1240 1250 1260 1270
pF1KA0 --DEPAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPSDPSHQISPGPTWDIKREHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKDEPAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPSDPSHQISPGPTWDIKREHD
1120 1130 1140 1150 1160 1170
1280 1290 1300 1310 1320 1330
pF1KA0 VRKPKELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGGQGRPEAGRPASEARAPGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRKPKELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGGQGRPEAGRPASEARAPGLA
1180 1190 1200 1210 1220 1230
1340 1350 1360 1370 1380 1390
pF1KA0 AADAADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGSGALEAEGRAGARAGPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AADAADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGSGALEAEGRAGARAGPR
1240 1250 1260 1270 1280 1290
1400 1410 1420 1430 1440
pF1KA0 PGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAASR
::::::::::::::::::::
XP_016 PGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAASR
1300 1310 1320 1330
>>XP_016868331 (OMIM: 606382) PREDICTED: membrane-associ (1538 aa)
initn: 7460 init1: 3173 opt: 3213 Z-score: 1417.1 bits: 274.9 E(85289): 3.4e-72
Smith-Waterman score: 9425; 93.4% identity (93.4% similar) in 1505 aa overlap (24-1431:24-1528)
10 20 30 40 50 60
pF1KA0 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
:::::::::::::::::::::::::::::::::::::
XP_016 MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYYGTPKPPAEPAPLLLNVTDQILPGATPSAEGKRKRNKSVSNMEKASIEPPEEEEEERP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVNGNGVVVTPESSEHEDKSAGASGEMPSQPYPAPVYSQPEELKEQMDDTKPTKPEDNEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDP
310 320 330 340 350 360
370 380 390 400
pF1KA0 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFR------------
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGTKPLQAPGFRVDSSSWTLPRPK
370 380 390 400 410 420
410 420 430
pF1KA0 -------------------------------EKPLFTRDASQLKGTFLSTTLKKSNMGFG
:::::::::::::::::::::::::::::
XP_016 SIRPRAAPERSRSVNDLSYYQRDPAGRPWLFEKPLFTRDASQLKGTFLSTTLKKSNMGFG
430 440 450 460 470 480
440 450 460 470 480 490
pF1KA0 FTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVP
490 500 510 520 530 540
500 510 520 530 540 550
pF1KA0 IGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNGRHNYETYLEYISRTSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNGRHNYETYLEYISRTSQS
550 560 570 580 590 600
560 570 580 590 600 610
pF1KA0 VPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQGFGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQGFGF
610 620 630 640 650 660
620 630 640 650 660 670
pF1KA0 TIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPIGSETSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPIGSETSL
670 680 690 700 710 720
680 690 700 710 720 730
pF1KA0 IIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFPPALHRSSFPDSTEAFDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIHRGGFFSPWKTPKPIMDRWENQGSPQTSLSAPAIPQNLPFPPALHRSSFPDSTEAFDP
730 740 750 760 770 780
740 750 760 770 780
pF1KA0 RKPDPYELYEKSRAIYE------------SRRPDYKELDVHLRRMESGFGFRILGGDEPG
::::::::::::::::: : ::::::::::::::::::::::::::::
XP_016 RKPDPYELYEKSRAIYEKQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGGDEPG
790 800 810 820 830 840
790 800 810 820 830 840
pF1KA0 QPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVR
850 860 870 880 890 900
850 860 870 880 890 900
pF1KA0 RKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASPPEGFASHSLQTS
910 920 930 940 950 960
910 920 930 940 950 960
pF1KA0 DVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVN
970 980 990 1000 1010 1020
970 980 990 1000 1010 1020
pF1KA0 GQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQSPLAQQSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQSPLAQQSPL
1030 1040 1050 1060 1070 1080
1030 1040 1050 1060 1070 1080
pF1KA0 AQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQPSPATPNSPIAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYR
1090 1100 1110 1120 1130 1140
1090 1100 1110 1120 1130 1140
pF1KA0 QPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGAKGFGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPGGDYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGAKGFGF
1150 1160 1170 1180 1190 1200
1150 1160 1170 1180 1190 1200
pF1KA0 SIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGR
1210 1220 1230 1240 1250 1260
1210 1220
pF1KA0 RVRLLLKRGTGQVPEY------------------------------------------DE
:::::::::::::::: ::
XP_016 RVRLLLKRGTGQVPEYGMVPSSLSMCMKSDKHGSPYFYLLGHPKDTERSKLARTDNRKDE
1270 1280 1290 1300 1310 1320
1230 1240 1250 1260 1270 1280
pF1KA0 PAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPSDPSHQISPGPTWDIKREHDVRKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAPWSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPSDPSHQISPGPTWDIKREHDVRKP
1330 1340 1350 1360 1370 1380
1290 1300 1310 1320 1330 1340
pF1KA0 KELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGGQGRPEAGRPASEARAPGLAAADA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KELSACGQKKQRLGEQRERSASPQRAARPRLEEAPGGQGRPEAGRPASEARAPGLAAADA
1390 1400 1410 1420 1430 1440
1350 1360 1370 1380 1390 1400
pF1KA0 ADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGSGALEAEGRAGARAGPRPGPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGSGALEAEGRAGARAGPRPGPR
1450 1460 1470 1480 1490 1500
1410 1420 1430 1440
pF1KA0 PPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAASR
::::::::::::::::::::::::::::
XP_016 PPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAASR
1510 1520 1530
1441 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:21:22 2016 done: Sat Nov 5 23:21:25 2016
Total Scan time: 20.940 Total Display time: 0.750
Function used was FASTA [36.3.4 Apr, 2011]