Result of FASTA (omim) for
pFN21AB7694
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7694, 413 aa
1>>>pF1KB7694 413 - 413 aa - 413 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8433+/-0.000298; mu= 7.7038+/- 0.019
mean_var=177.7846+/-37.586, 0's: 0 Z-trim(122.6): 46 B-trim: 2166 in 1/60
Lambda= 0.096189
statistics sampled from 41053 (41099) to 41053 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.482), width: 16
Scan time: 8.120
The best scores are: opt bits E(85289)
NP_002040 (OMIM: 190685,300367,300835,305371,31405 ( 413) 2847 406.7 5.3e-113
XP_011542199 (OMIM: 190685,300367,300835,305371,31 ( 418) 2827 404.0 3.7e-112
XP_011542200 (OMIM: 190685,300367,300835,305371,31 ( 335) 2278 327.7 2.7e-89
NP_116027 (OMIM: 137295,614038,614172,614286) endo ( 480) 830 126.9 1.1e-28
NP_001139133 (OMIM: 137295,614038,614172,614286) e ( 480) 830 126.9 1.1e-28
XP_005252500 (OMIM: 131320,146255) PREDICTED: tran ( 444) 789 121.2 5.3e-27
NP_001002295 (OMIM: 131320,146255) trans-acting T- ( 444) 789 121.2 5.3e-27
XP_005252499 (OMIM: 131320,146255) PREDICTED: tran ( 444) 789 121.2 5.3e-27
NP_002042 (OMIM: 131320,146255) trans-acting T-cel ( 443) 781 120.0 1.1e-26
NP_536721 (OMIM: 611496) transcription factor GATA ( 397) 701 108.9 2.3e-23
XP_006723762 (OMIM: 611496) PREDICTED: transcripti ( 397) 701 108.9 2.3e-23
NP_001295022 (OMIM: 187500,600576,607941,614429,61 ( 443) 694 108.0 4.9e-23
XP_016868801 (OMIM: 187500,600576,607941,614429,61 ( 443) 694 108.0 4.9e-23
XP_006716311 (OMIM: 187500,600576,607941,614429,61 ( 443) 694 108.0 4.9e-23
XP_005272443 (OMIM: 187500,600576,607941,614429,61 ( 443) 694 108.0 4.9e-23
XP_011542119 (OMIM: 187500,600576,607941,614429,61 ( 443) 694 108.0 4.9e-23
XP_005272442 (OMIM: 187500,600576,607941,614429,61 ( 443) 694 108.0 4.9e-23
XP_011542120 (OMIM: 187500,600576,607941,614429,61 ( 443) 694 108.0 4.9e-23
NP_001295023 (OMIM: 187500,600576,607941,614429,61 ( 236) 687 106.8 6e-23
NP_002043 (OMIM: 187500,600576,607941,614429,61443 ( 442) 691 107.6 6.5e-23
NP_005248 (OMIM: 187500,217095,600001,601656,61447 ( 595) 639 100.4 1.2e-20
NP_001139134 (OMIM: 137295,614038,614172,614286) e ( 466) 440 72.7 2.1e-12
XP_011515570 (OMIM: 190350,190351,604386) PREDICTE (1281) 221 42.7 0.0063
NP_001317528 (OMIM: 190350,190351,604386) zinc fin (1281) 221 42.7 0.0063
NP_001269831 (OMIM: 190350,190351,604386) zinc fin (1285) 221 42.7 0.0063
NP_001269832 (OMIM: 190350,190351,604386) zinc fin (1287) 221 42.7 0.0063
XP_011515569 (OMIM: 190350,190351,604386) PREDICTE (1287) 221 42.7 0.0063
XP_011515568 (OMIM: 190350,190351,604386) PREDICTE (1294) 221 42.7 0.0063
XP_011515566 (OMIM: 190350,190351,604386) PREDICTE (1294) 221 42.7 0.0063
NP_054831 (OMIM: 190350,190351,604386) zinc finger (1294) 221 42.7 0.0063
XP_006716688 (OMIM: 190350,190351,604386) PREDICTE (1294) 221 42.7 0.0063
XP_016869290 (OMIM: 190350,190351,604386) PREDICTE (1317) 221 42.7 0.0064
>>NP_002040 (OMIM: 190685,300367,300835,305371,314050) e (413 aa)
initn: 2847 init1: 2847 opt: 2847 Z-score: 2149.7 bits: 406.7 E(85289): 5.3e-113
Smith-Waterman score: 2847; 100.0% identity (100.0% similar) in 413 aa overlap (1-413:1-413)
10 20 30 40 50 60
pF1KB7 MEFPGLGSLGTSEPLPQFVDPALVSSTPESGVFFPSGPEGLDAAASSTAPSTATAAAAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MEFPGLGSLGTSEPLPQFVDPALVSSTPESGVFFPSGPEGLDAAASSTAPSTATAAAAAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 AYYRDAEAYRHSPVFQVYPLLNCMEGIPGGSPYAGWAYGKTGLYPASTVCPTREDSPPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AYYRDAEAYRHSPVFQVYPLLNCMEGIPGGSPYAGWAYGKTGLYPASTVCPTREDSPPQA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VEDLDGKGSTSFLETLKTERLSPDLLTLGPALPSSLPVPNSAYGGPDFSSTFFSPTGSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VEDLDGKGSTSFLETLKTERLSPDLLTLGPALPSSLPVPNSAYGGPDFSSTFFSPTGSPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 NSAAYSSPKLRGTLPLPPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NSAAYSSPKLRGTLPLPPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNRP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 LIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRKD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 GIQTRNRKASGKGKKKRGSSLGGTGAAEGPAGGFMVVAGGSGSGNCGEVASGLTLGPPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GIQTRNRKASGKGKKKRGSSLGGTGAAEGPAGGFMVVAGGSGSGNCGEVASGLTLGPPGT
310 320 330 340 350 360
370 380 390 400 410
pF1KB7 AHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTGSFPTGPMPPTTSTTVVAPLSS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTGSFPTGPMPPTTSTTVVAPLSS
370 380 390 400 410
>>XP_011542199 (OMIM: 190685,300367,300835,305371,314050 (418 aa)
initn: 2013 init1: 2013 opt: 2827 Z-score: 2134.6 bits: 404.0 E(85289): 3.7e-112
Smith-Waterman score: 2827; 98.8% identity (98.8% similar) in 418 aa overlap (1-413:1-418)
10 20 30 40 50 60
pF1KB7 MEFPGLGSLGTSEPLPQFVDPALVSSTPESGVFFPSGPEGLDAAASSTAPSTATAAAAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEFPGLGSLGTSEPLPQFVDPALVSSTPESGVFFPSGPEGLDAAASSTAPSTATAAAAAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 AYYRDAEAYRHSPVFQVYPLLNCMEGIPGGSPYAGWAYGKTGLYPASTVCPTREDSPPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYYRDAEAYRHSPVFQVYPLLNCMEGIPGGSPYAGWAYGKTGLYPASTVCPTREDSPPQA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VEDLDGKGSTSFLETLKTERLSPDLLTLGPALPSSLPVPNSAYGGPDFSSTFFSPTGSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEDLDGKGSTSFLETLKTERLSPDLLTLGPALPSSLPVPNSAYGGPDFSSTFFSPTGSPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 NSAAYSSPKLRGTLPLPPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSAAYSSPKLRGTLPLPPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNRP
190 200 210 220 230 240
250 260 270 280 290
pF1KB7 LIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQ-----VNRPL
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_011 LIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQPPFWQVNRPL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 TMRKDGIQTRNRKASGKGKKKRGSSLGGTGAAEGPAGGFMVVAGGSGSGNCGEVASGLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMRKDGIQTRNRKASGKGKKKRGSSLGGTGAAEGPAGGFMVVAGGSGSGNCGEVASGLTL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 GPPGTAHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTGSFPTGPMPPTTSTTVVAPLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPPGTAHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTGSFPTGPMPPTTSTTVVAPLSS
370 380 390 400 410
>>XP_011542200 (OMIM: 190685,300367,300835,305371,314050 (335 aa)
initn: 1464 init1: 1464 opt: 2278 Z-score: 1724.2 bits: 327.7 E(85289): 2.7e-89
Smith-Waterman score: 2278; 98.5% identity (98.5% similar) in 335 aa overlap (84-413:1-335)
60 70 80 90 100 110
pF1KB7 TAAAAALAYYRDAEAYRHSPVFQVYPLLNCMEGIPGGSPYAGWAYGKTGLYPASTVCPTR
::::::::::::::::::::::::::::::
XP_011 MEGIPGGSPYAGWAYGKTGLYPASTVCPTR
10 20 30
120 130 140 150 160 170
pF1KB7 EDSPPQAVEDLDGKGSTSFLETLKTERLSPDLLTLGPALPSSLPVPNSAYGGPDFSSTFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDSPPQAVEDLDGKGSTSFLETLKTERLSPDLLTLGPALPSSLPVPNSAYGGPDFSSTFF
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB7 SPTGSPLNSAAYSSPKLRGTLPLPPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPTGSPLNSAAYSSPKLRGTLPLPPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHK
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB7 MNGQNRPLIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQ---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNGQNRPLIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQPPF
160 170 180 190 200 210
300 310 320 330 340
pF1KB7 --VNRPLTMRKDGIQTRNRKASGKGKKKRGSSLGGTGAAEGPAGGFMVVAGGSGSGNCGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WQVNRPLTMRKDGIQTRNRKASGKGKKKRGSSLGGTGAAEGPAGGFMVVAGGSGSGNCGE
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB7 VASGLTLGPPGTAHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTGSFPTGPMPPTTSTTVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VASGLTLGPPGTAHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTGSFPTGPMPPTTSTTVV
280 290 300 310 320 330
410
pF1KB7 APLSS
:::::
XP_011 APLSS
>>NP_116027 (OMIM: 137295,614038,614172,614286) endothel (480 aa)
initn: 956 init1: 724 opt: 830 Z-score: 636.1 bits: 126.9 E(85289): 1.1e-28
Smith-Waterman score: 846; 43.1% identity (61.3% similar) in 408 aa overlap (16-407:115-479)
10 20 30 40
pF1KB7 MEFPGLGSLGTSEPLPQFVDPALVSSTP--ESGVFFPSGPEGLDA
: :.: :.:: :.. :.:: ..
NP_116 CRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSP--FSKTPLHPSAAGGPGGPLSVYP
90 100 110 120 130 140
50 60 70 80 90 100
pF1KB7 AASSTAPSTATAAAAALAYYRDAEAYRHSPVFQVYPLLNCMEGIPGGSPYAGWAYGKTGL
.:.. . . . ...:.:. . :. : .: .: : : : .: :
NP_116 GAGGGSGGGSGSSVASLT---PTAAHSGSHLFG-FPPTPPKEVSPDPST-TGAAS-----
150 160 170 180 190
110 120 130 140 150
pF1KB7 YPASTVCPTREDSPPQAVEDLDG-KGSTSFLETLKTER---LSPDLLTLGPALPSSLPVP
:::. . : .. :: :: : ..:. :..: : : : : :.: . :.:
NP_116 -PASS---SAGGSAARG-EDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIP
200 210 220 230 240
160 170 180 190 200 210
pF1KB7 NSAYGGP----DFSSTFFSPTGSPLNSAAYSSPKLRGTLPLPPC-EARECVNCGATATPL
. : :.:: .: : : . :. .:: :. : :.:::::::::::::
NP_116 TYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKAR--SCSEGRECVNCGATATPL
250 260 270 280 290 300
220 230 240 250 260 270
pF1KB7 WRRDRTGHYLCNACGLYHKMNGQNRPLIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNAS
:::: :::::::::::::::::::::::.::.:: ...:::: :.::::::::::::::.
NP_116 WRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNAN
310 320 330 340 350 360
280 290 300 310 320 330
pF1KB7 GDPVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKASGKGKK-KRGSSLGGTGAAEGPAGG
:::::::::::::::.:::::::.:.:::::::: :.:.:: :.: :
NP_116 GDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKG------------AEC
370 380 390 400 410
340 350 360 370 380 390
pF1KB7 FMVVAGGSGSGNCGEVASGLTLGPPGTAHLYQGLGPVVLSGPVSH---LMPFPGPLLGSP
: .. .: . :. : ..: : ..:: : :: ..: : :. :
NP_116 FEELS------KCMQEKSS----PFSAAALAGHMAPVGHLPPFSHSGHILPTPTPI--HP
420 430 440 450 460
400 410
pF1KB7 TGSFPTG-PMPPTTSTTVVAPLSS
..:. : : : . :..
NP_116 SSSLSFGHPHPSSMVTAMG
470 480
>>NP_001139133 (OMIM: 137295,614038,614172,614286) endot (480 aa)
initn: 956 init1: 724 opt: 830 Z-score: 636.1 bits: 126.9 E(85289): 1.1e-28
Smith-Waterman score: 846; 43.1% identity (61.3% similar) in 408 aa overlap (16-407:115-479)
10 20 30 40
pF1KB7 MEFPGLGSLGTSEPLPQFVDPALVSSTP--ESGVFFPSGPEGLDA
: :.: :.:: :.. :.:: ..
NP_001 CRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSP--FSKTPLHPSAAGGPGGPLSVYP
90 100 110 120 130 140
50 60 70 80 90 100
pF1KB7 AASSTAPSTATAAAAALAYYRDAEAYRHSPVFQVYPLLNCMEGIPGGSPYAGWAYGKTGL
.:.. . . . ...:.:. . :. : .: .: : : : .: :
NP_001 GAGGGSGGGSGSSVASLT---PTAAHSGSHLFG-FPPTPPKEVSPDPST-TGAAS-----
150 160 170 180 190
110 120 130 140 150
pF1KB7 YPASTVCPTREDSPPQAVEDLDG-KGSTSFLETLKTER---LSPDLLTLGPALPSSLPVP
:::. . : .. :: :: : ..:. :..: : : : : :.: . :.:
NP_001 -PASS---SAGGSAARG-EDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIP
200 210 220 230 240
160 170 180 190 200 210
pF1KB7 NSAYGGP----DFSSTFFSPTGSPLNSAAYSSPKLRGTLPLPPC-EARECVNCGATATPL
. : :.:: .: : : . :. .:: :. : :.:::::::::::::
NP_001 TYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKAR--SCSEGRECVNCGATATPL
250 260 270 280 290 300
220 230 240 250 260 270
pF1KB7 WRRDRTGHYLCNACGLYHKMNGQNRPLIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNAS
:::: :::::::::::::::::::::::.::.:: ...:::: :.::::::::::::::.
NP_001 WRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNAN
310 320 330 340 350 360
280 290 300 310 320 330
pF1KB7 GDPVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKASGKGKK-KRGSSLGGTGAAEGPAGG
:::::::::::::::.:::::::.:.:::::::: :.:.:: :.: :
NP_001 GDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKG------------AEC
370 380 390 400 410
340 350 360 370 380 390
pF1KB7 FMVVAGGSGSGNCGEVASGLTLGPPGTAHLYQGLGPVVLSGPVSH---LMPFPGPLLGSP
: .. .: . :. : ..: : ..:: : :: ..: : :. :
NP_001 FEELS------KCMQEKSS----PFSAAALAGHMAPVGHLPPFSHSGHILPTPTPI--HP
420 430 440 450 460
400 410
pF1KB7 TGSFPTG-PMPPTTSTTVVAPLSS
..:. : : : . :..
NP_001 SSSLSFGHPHPSSMVTAMG
470 480
>>XP_005252500 (OMIM: 131320,146255) PREDICTED: trans-ac (444 aa)
initn: 777 init1: 725 opt: 789 Z-score: 605.8 bits: 121.2 E(85289): 5.3e-27
Smith-Waterman score: 795; 41.2% identity (61.2% similar) in 381 aa overlap (51-408:105-443)
30 40 50 60 70
pF1KB7 PALVSSTPESGVFFPSGPEGLDAAASSTAPSTATAAAAALAYYRDAEAYRHSP-VFQVYP
: ::. :. . . .. :: ..:::
XP_005 YPPTHHGSQVCRPPLLHGSLPWLDGGKALGSHHTASPWNLSPFSKTSIHHGSPGPLSVYP
80 90 100 110 120 130
80 90 100 110 120 130
pF1KB7 LLNCMEGIPGG--SPYAGWAYGKTGLYPASTVCPTREDSPPQAVEDLDGKGSTSFLETLK
. .. :: ::. ... : : . : : : : .. :.. . : ::
XP_005 PASS-SSLSGGHASPHL-FTFPPT---PPKDVSPDPSLSTPGSA----GSARQDEKECLK
140 150 160 170 180
140 150 160 170
pF1KB7 TERLSPD------------LLTLGPALPSSLPVPNSAYGG--PDFSSTFFSPT----GSP
. :: . .:: : :: : ..: :..:: .: :. :::
XP_005 YQVPLPDSMKLESSHSRGSMTALGGA-SSSTHHPITTYPPYVPEYSSGLFPPSSLLGGSP
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB7 LNSAAYSSPKLRGTLPLPPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNR
. . : :: :.. :.:::::::::.::::::: ::::::::::::::::::::
XP_005 TGFGCKSRPKARSST-----EGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNR
250 260 270 280 290
240 250 260 270 280 290
pF1KB7 PLIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRK
:::.::.:: ...::::.:.::::::::::::::.:::::::::::::::..::::::.:
XP_005 PLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKK
300 310 320 330 340 350
300 310 320 330 340 350
pF1KB7 DGIQTRNRKASGKGKK--KRGSSLGGTGAAEGPAGGFMVVAGGSGSGNCGEVASGLTLGP
.:::::::: :.:.:: : .:: . : .. ...:
XP_005 EGIQTRNRKMSSKSKKCKKVHDSL-----EDFPKNS--------------------SFNP
360 370 380 390
360 370 380 390 400 410
pF1KB7 PGTAHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTGSFPTGPMPPTTSTTVVAPLSS
. .. ...:. . . ::.. : :. : .:. :: :.. .:..
XP_005 AALSRHMSSLSHISPFSHSSHMLTTPTPM--HPPSSLSFGPHHPSSMVTAMG
400 410 420 430 440
>>NP_001002295 (OMIM: 131320,146255) trans-acting T-cell (444 aa)
initn: 777 init1: 725 opt: 789 Z-score: 605.8 bits: 121.2 E(85289): 5.3e-27
Smith-Waterman score: 795; 41.2% identity (61.2% similar) in 381 aa overlap (51-408:105-443)
30 40 50 60 70
pF1KB7 PALVSSTPESGVFFPSGPEGLDAAASSTAPSTATAAAAALAYYRDAEAYRHSP-VFQVYP
: ::. :. . . .. :: ..:::
NP_001 YPPTHHGSQVCRPPLLHGSLPWLDGGKALGSHHTASPWNLSPFSKTSIHHGSPGPLSVYP
80 90 100 110 120 130
80 90 100 110 120 130
pF1KB7 LLNCMEGIPGG--SPYAGWAYGKTGLYPASTVCPTREDSPPQAVEDLDGKGSTSFLETLK
. .. :: ::. ... : : . : : : : .. :.. . : ::
NP_001 PASS-SSLSGGHASPHL-FTFPPT---PPKDVSPDPSLSTPGSA----GSARQDEKECLK
140 150 160 170 180
140 150 160 170
pF1KB7 TERLSPD------------LLTLGPALPSSLPVPNSAYGG--PDFSSTFFSPT----GSP
. :: . .:: : :: : ..: :..:: .: :. :::
NP_001 YQVPLPDSMKLESSHSRGSMTALGGA-SSSTHHPITTYPPYVPEYSSGLFPPSSLLGGSP
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB7 LNSAAYSSPKLRGTLPLPPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNR
. . : :: :.. :.:::::::::.::::::: ::::::::::::::::::::
NP_001 TGFGCKSRPKARSST-----EGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNR
250 260 270 280 290
240 250 260 270 280 290
pF1KB7 PLIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRK
:::.::.:: ...::::.:.::::::::::::::.:::::::::::::::..::::::.:
NP_001 PLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKK
300 310 320 330 340 350
300 310 320 330 340 350
pF1KB7 DGIQTRNRKASGKGKK--KRGSSLGGTGAAEGPAGGFMVVAGGSGSGNCGEVASGLTLGP
.:::::::: :.:.:: : .:: . : .. ...:
NP_001 EGIQTRNRKMSSKSKKCKKVHDSL-----EDFPKNS--------------------SFNP
360 370 380 390
360 370 380 390 400 410
pF1KB7 PGTAHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTGSFPTGPMPPTTSTTVVAPLSS
. .. ...:. . . ::.. : :. : .:. :: :.. .:..
NP_001 AALSRHMSSLSHISPFSHSSHMLTTPTPM--HPPSSLSFGPHHPSSMVTAMG
400 410 420 430 440
>>XP_005252499 (OMIM: 131320,146255) PREDICTED: trans-ac (444 aa)
initn: 777 init1: 725 opt: 789 Z-score: 605.8 bits: 121.2 E(85289): 5.3e-27
Smith-Waterman score: 795; 41.2% identity (61.2% similar) in 381 aa overlap (51-408:105-443)
30 40 50 60 70
pF1KB7 PALVSSTPESGVFFPSGPEGLDAAASSTAPSTATAAAAALAYYRDAEAYRHSP-VFQVYP
: ::. :. . . .. :: ..:::
XP_005 YPPTHHGSQVCRPPLLHGSLPWLDGGKALGSHHTASPWNLSPFSKTSIHHGSPGPLSVYP
80 90 100 110 120 130
80 90 100 110 120 130
pF1KB7 LLNCMEGIPGG--SPYAGWAYGKTGLYPASTVCPTREDSPPQAVEDLDGKGSTSFLETLK
. .. :: ::. ... : : . : : : : .. :.. . : ::
XP_005 PASS-SSLSGGHASPHL-FTFPPT---PPKDVSPDPSLSTPGSA----GSARQDEKECLK
140 150 160 170 180
140 150 160 170
pF1KB7 TERLSPD------------LLTLGPALPSSLPVPNSAYGG--PDFSSTFFSPT----GSP
. :: . .:: : :: : ..: :..:: .: :. :::
XP_005 YQVPLPDSMKLESSHSRGSMTALGGA-SSSTHHPITTYPPYVPEYSSGLFPPSSLLGGSP
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB7 LNSAAYSSPKLRGTLPLPPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNR
. . : :: :.. :.:::::::::.::::::: ::::::::::::::::::::
XP_005 TGFGCKSRPKARSST-----EGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNR
250 260 270 280 290
240 250 260 270 280 290
pF1KB7 PLIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRK
:::.::.:: ...::::.:.::::::::::::::.:::::::::::::::..::::::.:
XP_005 PLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKK
300 310 320 330 340 350
300 310 320 330 340 350
pF1KB7 DGIQTRNRKASGKGKK--KRGSSLGGTGAAEGPAGGFMVVAGGSGSGNCGEVASGLTLGP
.:::::::: :.:.:: : .:: . : .. ...:
XP_005 EGIQTRNRKMSSKSKKCKKVHDSL-----EDFPKNS--------------------SFNP
360 370 380 390
360 370 380 390 400 410
pF1KB7 PGTAHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTGSFPTGPMPPTTSTTVVAPLSS
. .. ...:. . . ::.. : :. : .:. :: :.. .:..
XP_005 AALSRHMSSLSHISPFSHSSHMLTTPTPM--HPPSSLSFGPHHPSSMVTAMG
400 410 420 430 440
>>NP_002042 (OMIM: 131320,146255) trans-acting T-cell-sp (443 aa)
initn: 771 init1: 719 opt: 781 Z-score: 599.8 bits: 120.0 E(85289): 1.1e-26
Smith-Waterman score: 787; 40.9% identity (60.9% similar) in 381 aa overlap (51-408:105-442)
30 40 50 60 70
pF1KB7 PALVSSTPESGVFFPSGPEGLDAAASSTAPSTATAAAAALAYYRDAEAYRHSP-VFQVYP
: ::. :. . . .. :: ..:::
NP_002 YPPTHHGSQVCRPPLLHGSLPWLDGGKALGSHHTASPWNLSPFSKTSIHHGSPGPLSVYP
80 90 100 110 120 130
80 90 100 110 120 130
pF1KB7 LLNCMEGIPGG--SPYAGWAYGKTGLYPASTVCPTREDSPPQAVEDLDGKGSTSFLETLK
. .. :: ::. ... : : . : : : : .. :.. . : ::
NP_002 PASS-SSLSGGHASPHL-FTFPPT---PPKDVSPDPSLSTPGSA----GSARQDEKECLK
140 150 160 170 180
140 150 160 170
pF1KB7 TERLSPD------------LLTLGPALPSSLPVPNSAYGG--PDFSSTFFSPT----GSP
. :: . .:: : :: : ..: :..:: .: :. :::
NP_002 YQVPLPDSMKLESSHSRGSMTALGGA-SSSTHHPITTYPPYVPEYSSGLFPPSSLLGGSP
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB7 LNSAAYSSPKLRGTLPLPPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNR
. . : :: :.. .:::::::::.::::::: ::::::::::::::::::::
NP_002 TGFGCKSRPKARSST------GRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNR
250 260 270 280 290
240 250 260 270 280 290
pF1KB7 PLIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRK
:::.::.:: ...::::.:.::::::::::::::.:::::::::::::::..::::::.:
NP_002 PLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKK
300 310 320 330 340 350
300 310 320 330 340 350
pF1KB7 DGIQTRNRKASGKGKK--KRGSSLGGTGAAEGPAGGFMVVAGGSGSGNCGEVASGLTLGP
.:::::::: :.:.:: : .:: . : .. ...:
NP_002 EGIQTRNRKMSSKSKKCKKVHDSL-----EDFPKNS--------------------SFNP
360 370 380 390
360 370 380 390 400 410
pF1KB7 PGTAHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTGSFPTGPMPPTTSTTVVAPLSS
. .. ...:. . . ::.. : :. : .:. :: :.. .:..
NP_002 AALSRHMSSLSHISPFSHSSHMLTTPTPM--HPPSSLSFGPHHPSSMVTAMG
400 410 420 430 440
>>NP_536721 (OMIM: 611496) transcription factor GATA-5 [ (397 aa)
initn: 720 init1: 633 opt: 701 Z-score: 540.5 bits: 108.9 E(85289): 2.3e-23
Smith-Waterman score: 721; 39.8% identity (58.7% similar) in 402 aa overlap (4-400:26-378)
10 20 30
pF1KB7 MEFPGLGSLGTSEPLPQFVDPALVSS--TPESGVFFPS
:: :: :.:: :: : : . :: ::
NP_536 MYQSLALAASPRQAAYADSGSFLHAPGAGS-------PMFVPPARVPSMLSYLSGCE-PS
10 20 30 40 50
40 50 60 70 80 90
pF1KB7 GPEGLDAAASSTAPSTATAAAAALAYYRDAEAYRHSPVFQVYPLLNCMEGIPGGSPYAGW
:. . :: .:::: ..:.. : : ..:. . : ::.. ::
NP_536 -PQPPELAARPGWAQTATADSSAFGPGSPHPPAAHPPGATAFPFAHSPSG-PGSGGSAG-
60 70 80 90 100
100 110 120 130 140 150
pF1KB7 AYGKTGLYPASTVCPTREDSPPQAVEDLDGKGSTSFLETLKTERLSPDLLTLGPALPSSL
:. : ... : .. . : : .::. : . .:::
NP_536 --GRDGSAYQGALLPREQFAAP-----LGRPVGTSYSATYPA-YVSPD------------
110 120 130 140
160 170 180 190 200 210
pF1KB7 PVPNSAYGGPDFSSTFFSPTGSPLNSAAYSSPKLRGTLPLPPCEARECVNCGATATPLWR
: .: .:: :... . : : .. : :. : :.:::::::: .:::::
NP_536 -VAQSWTAGP-FDGSVLH--GLPGRRPTFVSDFLEEF----PGEGRECVNCGALSTPLWR
150 160 170 180 190 200
220 230 240 250 260 270
pF1KB7 RDRTGHYLCNACGLYHKMNGQNRPLIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGD
:: ::::::::::::::::: ::::.::.::: :.::: ::::.::.:::::::. :.
NP_536 RDGTGHYLCNACGLYHKMNGVNRPLVRPQKRLSSSRRAGLCCTNCHTTNTTLWRRNSEGE
210 220 230 240 250 260
280 290 300 310 320 330
pF1KB7 PVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGSSLGGTGAAEGPAGGFMV
:::::::::.::: : :::.:.:..::::.:: . .: :::: . .:. .:..
NP_536 PVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKTIAKA-RGSSGSTRNASASPSA----
270 280 290 300 310
340 350 360 370 380 390
pF1KB7 VAGGSGSGNCGEVASGLTLGP--PGTAHLYQGLGPVVLSGPVSHL-MPFPGPLLGSPTGS
::. ..:. ... .:. .: :: . :. : : .:: . : .. :.
NP_536 VASTDSSAATSKAKPSLA-SPVCPGPSMAPQASGQEDDSLAPGHLEFKFEPEDFAFPS--
320 330 340 350 360 370
400 410
pF1KB7 FPTGPMPPTTSTTVVAPLSS
:.: :
NP_536 --TAPSPQAGLRGALRQEAWCALALA
380 390
413 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:36:02 2016 done: Fri Nov 4 21:36:03 2016
Total Scan time: 8.120 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]