Result of FASTA (omim) for
pFN21AB6305
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6305, 258 aa
1>>>pF1KB6305 258 - 258 aa - 258 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8018+/-0.000362; mu= 17.5314+/- 0.023
mean_var=64.8830+/-13.217, 0's: 0 Z-trim(113.5): 306 B-trim: 419 in 1/57
Lambda= 0.159224
statistics sampled from 22560 (22880) to 22560 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.268), width: 16
Scan time: 5.720
The best scores are: opt bits E(85289)
NP_001962 (OMIM: 130120) chymotrypsin-like elastas ( 258) 1753 411.3 8.8e-115
NP_254275 (OMIM: 609443) chymotrypsin-like elastas ( 269) 997 237.6 1.7e-62
NP_056933 (OMIM: 609444) chymotrypsin-like elastas ( 269) 962 229.6 4.5e-60
NP_009203 (OMIM: 167800,601405) chymotrypsin-C pre ( 268) 852 204.3 1.8e-52
NP_001898 (OMIM: 118888) chymotrypsin-like proteas ( 264) 617 150.3 3.2e-36
NP_001897 (OMIM: 118890) chymotrypsinogen B isofor ( 263) 552 135.4 1e-31
XP_016863673 (OMIM: 229000,612423) PREDICTED: plas ( 436) 553 135.8 1.3e-31
NP_001305325 (OMIM: 229000,612423) plasma kallikre ( 436) 553 135.8 1.3e-31
NP_000883 (OMIM: 229000,612423) plasma kallikrein ( 638) 553 135.9 1.7e-31
XP_011530232 (OMIM: 229000,612423) PREDICTED: plas ( 649) 553 135.9 1.7e-31
XP_016863670 (OMIM: 229000,612423) PREDICTED: plas ( 649) 553 135.9 1.7e-31
XP_005262880 (OMIM: 264900,612416) PREDICTED: coag ( 536) 548 134.7 3.3e-31
XP_006714200 (OMIM: 264900,612416) PREDICTED: coag ( 610) 548 134.8 3.6e-31
NP_000119 (OMIM: 264900,612416) coagulation factor ( 625) 548 134.8 3.7e-31
XP_005262878 (OMIM: 264900,612416) PREDICTED: coag ( 626) 548 134.8 3.7e-31
NP_000292 (OMIM: 173350,217090) plasminogen isofor ( 810) 548 134.9 4.5e-31
NP_001231924 (OMIM: 610050) transmembrane protease ( 563) 537 132.2 2e-30
NP_892028 (OMIM: 142440) serine protease hepsin pr ( 417) 535 131.7 2.1e-30
XP_016882220 (OMIM: 142440) PREDICTED: serine prot ( 417) 535 131.7 2.1e-30
XP_006723244 (OMIM: 142440) PREDICTED: serine prot ( 417) 535 131.7 2.1e-30
XP_005258895 (OMIM: 142440) PREDICTED: serine prot ( 417) 535 131.7 2.1e-30
NP_002142 (OMIM: 142440) serine protease hepsin pr ( 417) 535 131.7 2.1e-30
NP_001193718 (OMIM: 610050) transmembrane protease ( 532) 536 132.0 2.2e-30
NP_001070731 (OMIM: 610050) transmembrane protease ( 567) 536 132.0 2.3e-30
XP_016882221 (OMIM: 142440) PREDICTED: serine prot ( 393) 533 131.2 2.8e-30
NP_077078 (OMIM: 191081) tryptase beta-2 prepropro ( 275) 528 129.9 4.7e-30
NP_003285 (OMIM: 191080) tryptase alpha/beta-1 pre ( 275) 525 129.2 7.6e-30
NP_001243246 (OMIM: 605511) transmembrane protease ( 453) 509 125.7 1.4e-28
XP_005262454 (OMIM: 122700,300746,300807,306900) P ( 418) 508 125.5 1.6e-28
NP_001300842 (OMIM: 122700,300746,300807,306900) c ( 423) 508 125.5 1.6e-28
NP_000124 (OMIM: 122700,300746,300807,306900) coag ( 461) 508 125.5 1.7e-28
NP_001171131 (OMIM: 188050,603924,616535) hyaluron ( 534) 504 124.6 3.6e-28
NP_004123 (OMIM: 188050,603924,616535) hyaluronan- ( 560) 504 124.6 3.7e-28
XP_005255530 (OMIM: 609343) PREDICTED: brain-speci ( 317) 499 123.3 5.3e-28
NP_071402 (OMIM: 609343) brain-specific serine pro ( 317) 499 123.3 5.3e-28
NP_001277025 (OMIM: 606565) transmembrane protease ( 290) 497 122.8 6.9e-28
NP_115780 (OMIM: 605511) transmembrane protease se ( 327) 497 122.8 7.5e-28
NP_001167023 (OMIM: 606565) transmembrane protease ( 397) 497 122.9 8.7e-28
NP_001277023 (OMIM: 606565) transmembrane protease ( 412) 497 122.9 9e-28
NP_001077416 (OMIM: 606565) transmembrane protease ( 432) 497 122.9 9.3e-28
NP_001167022 (OMIM: 606565) transmembrane protease ( 435) 497 122.9 9.3e-28
NP_063947 (OMIM: 606565) transmembrane protease se ( 437) 497 122.9 9.4e-28
NP_076927 (OMIM: 605511) transmembrane protease se ( 454) 497 123.0 9.7e-28
NP_002760 (OMIM: 167800,276000,614044) trypsin-1 p ( 247) 493 121.8 1.1e-27
NP_003610 (OMIM: 249500,606709) neurotrypsin precu ( 875) 499 123.6 1.2e-27
XP_011514713 (OMIM: 167800,276000,614044) PREDICTE ( 472) 493 122.1 1.9e-27
XP_005271672 (OMIM: 606565) PREDICTED: transmembra ( 454) 485 120.2 6.5e-27
XP_011541204 (OMIM: 606565) PREDICTED: transmembra ( 456) 485 120.2 6.5e-27
XP_011541203 (OMIM: 606565) PREDICTED: transmembra ( 489) 485 120.2 6.9e-27
XP_005271671 (OMIM: 606565) PREDICTED: transmembra ( 492) 485 120.2 6.9e-27
>>NP_001962 (OMIM: 130120) chymotrypsin-like elastase fa (258 aa)
initn: 1753 init1: 1753 opt: 1753 Z-score: 2181.7 bits: 411.3 E(85289): 8.8e-115
Smith-Waterman score: 1753; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258)
10 20 30 40 50 60
pF1KB6 MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 YWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTV
190 200 210 220 230 240
250
pF1KB6 FTQVSAYISWINNVIASN
::::::::::::::::::
NP_001 FTQVSAYISWINNVIASN
250
>>NP_254275 (OMIM: 609443) chymotrypsin-like elastase fa (269 aa)
initn: 978 init1: 820 opt: 997 Z-score: 1242.9 bits: 237.6 E(85289): 1.7e-62
Smith-Waterman score: 997; 57.5% identity (80.6% similar) in 247 aa overlap (13-258:23-269)
10 20 30 40 50
pF1KB6 MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGG
: .::::: :: :::: :.:::: :.:. ::::::
NP_254 MIRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 TLIRQNWVMTAAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGY
.:: ..::.:::::.. ..:.:: : ::: .. :::.::::: :::.... :
NP_254 SLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGN
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 DIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPS
:::::.::. :.:.. .::. :: :.:: :: :::.::::. .::: . ..:::. :
NP_254 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLV
130 140 150 160 170 180
180 190 200 210 220
pF1KB6 VDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLV-NGKYSVHGVTSFVSS
:::: ::::..:::.::..:.::::::: :.:.:::::::.: . .:...:::..:: :
NP_254 VDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSR
190 200 210 220 230 240
230 240 250
pF1KB6 RGCNVSRKPTVFTQVSAYISWINNVIASN
::: .::.:::.:: ::.:::.:::.:
NP_254 LGCNYYHKPSVFTRVSNYIDWINSVIANN
250 260
>>NP_056933 (OMIM: 609444) chymotrypsin-like elastase fa (269 aa)
initn: 938 init1: 796 opt: 962 Z-score: 1199.4 bits: 229.6 E(85289): 4.5e-60
Smith-Waterman score: 962; 56.4% identity (79.0% similar) in 243 aa overlap (17-258:27-269)
10 20 30 40 50
pF1KB6 MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGG
.:..:: :: :::: :.:::: :.:. ::::::
NP_056 MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 TLIRQNWVMTAAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGY
.:: ..::.:::::.. . .::. :.::: .. :::.::::: ::::.:. :
NP_056 SLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGN
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 DIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPS
:::::.::. :.:.. .::. :: :.:: :: :::.::::. .::: : . :.:. :
NP_056 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLV
130 140 150 160 170 180
180 190 200 210 220
pF1KB6 VDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLV-NGKYSVHGVTSFVSS
:::: ::::..::::::..:.::::::: :.:::::::.: . .:.. :::. :..:
NP_056 VDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSV
190 200 210 220 230 240
230 240 250
pF1KB6 RGCNVSRKPTVFTQVSAYISWINNVIASN
::: ::..::.:: : .:::.:::.:
NP_056 LGCNYYYKPSIFTRVSNYNDWINSVIANN
250 260
>>NP_009203 (OMIM: 167800,601405) chymotrypsin-C preprop (268 aa)
initn: 418 init1: 418 opt: 852 Z-score: 1062.9 bits: 204.3 E(85289): 1.8e-52
Smith-Waterman score: 852; 52.3% identity (77.0% similar) in 243 aa overlap (13-252:24-263)
10 20 30 40
pF1KB6 MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCG
:. .:::::: .: .::: :::::: .. . ::::
NP_009 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 GTLIRQNWVMTAAHCVDYQKTFRVVAGDHNLSQND--GTEQYVSVQKIVVHPYWNSDNVA
:::: .:.:.:::::.. .:.::..: .:: .: :. .:.:. : :: ::. .
NP_009 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGS-LFVGVDTIHVHKRWNA--LL
70 80 90 100 110
110 120 130 140 150 160
pF1KB6 AGYDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAY
::::..::. : :.. .:.. ::.. ..: .. :::.::::. ::: .:. :::.
NP_009 LRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 LPSVDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHC-LVNGKYSVHGVTSF
: ::.: :: ..:: ::.:::::::::: :.:.:::::::.: : ::.. : :..::
NP_009 QPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSF
180 190 200 210 220 230
230 240 250
pF1KB6 VSSRGCNVSRKPTVFTQVSAYISWINNVIASN
: ::::. .::.:.:.:::::.:::
NP_009 GSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
240 250 260
>>NP_001898 (OMIM: 118888) chymotrypsin-like protease CT (264 aa)
initn: 484 init1: 194 opt: 617 Z-score: 771.2 bits: 150.3 E(85289): 3.2e-36
Smith-Waterman score: 617; 41.6% identity (69.5% similar) in 243 aa overlap (18-258:33-264)
10 20 30 40
pF1KB6 MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHT
:.:.: .: .::: :.::: :: .:
NP_001 LLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSG---FHF
10 20 30 40 50
50 60 70 80 90 100
pF1KB6 CGGTLIRQNWVMTAAHC-VDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNV
:::.:: :.::.::::: :. . : :: :... :.: : .::.. ..:: ::: ..
NP_001 CGGSLISQSWVVTAAHCNVSPGRHF-VVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTM
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 AAGYDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQT-LQQ
:..::.::. . .. .. : . . :... : ::::. . :... . :::
NP_001 NN--DVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQ
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 AYLPSVDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTS
. :: : : . ::::.. ..:.:::: :. :.::::::::: : .. . . :..:
NP_001 VALPLVTVNQCRQ--YWGSSITDSMICAGGAGA-SSCQGDSGGPLVCQKGNTWVLIGIVS
180 190 200 210 220 230
230 240 250
pF1KB6 FVSSRGCNVSRKPTVFTQVSAYISWINNVIASN
. ....::: : :.:.:.:: . .:::.::: :
NP_001 W-GTKNCNV-RAPAVYTRVSKFSTWINQVIAYN
240 250 260
>>NP_001897 (OMIM: 118890) chymotrypsinogen B isoform 1 (263 aa)
initn: 405 init1: 115 opt: 552 Z-score: 690.6 bits: 135.4 E(85289): 1e-31
Smith-Waterman score: 552; 37.4% identity (69.5% similar) in 243 aa overlap (17-258:32-263)
10 20 30 40
pF1KB6 MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYH
.:.:.: .: .::: :.::: ..: .:
NP_001 ASLWLLSCFSLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTG---FH
10 20 30 40 50
50 60 70 80 90 100
pF1KB6 TCGGTLIRQNWVMTAAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNV
:::.:: ..::.::::: . . ::::. . .... . : ... :. .: .. .:
NP_001 FCGGSLISEDWVVTAAHC-GVRTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTV
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 AAGYDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNG-QLAQTLQQ
. ::.::.:: . ... :. ::. . .. : ::::::: :. . . :::
NP_001 --NNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQ
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 AYLPSVDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTS
: :: .. : :..: :: . ..:.:::..:: :.:.::::::: : .: ... :..:
NP_001 AALPLLSNAECKKS--WGRRITDVMICAGASGV-SSCMGDSGGPLVCQKDGAWTLVGIVS
180 190 200 210 220 230
230 240 250
pF1KB6 FVSSRGCNVSRKPTVFTQVSAYISWINNVIASN
. .: :..: .: :...:. : :.....:.:
NP_001 W-GSDTCSTS-SPGVYARVTKLIPWVQKILAAN
240 250 260
>>XP_016863673 (OMIM: 229000,612423) PREDICTED: plasma k (436 aa)
initn: 435 init1: 269 opt: 553 Z-score: 688.8 bits: 135.8 E(85289): 1.3e-31
Smith-Waterman score: 553; 35.1% identity (65.7% similar) in 251 aa overlap (6-251:176-419)
10 20 30
pF1KB6 MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQIS
: .. .:..:.::::... . :: :.:
XP_016 FLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVS
150 160 170 180 190 200
40 50 60 70 80 90
pF1KB6 LQYRSGGSRYHTCGGTLIRQNWVMTAAHCVD---YQKTFRVVAGDHNLSQNDGTEQYVSV
:: . ..: : :::.:: ..::.::::: : : ..:. .: :::. . ..
XP_016 LQVKLTAQR-HLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQI
210 220 230 240 250 260
100 110 120 130 140 150
pF1KB6 QKIVVHPYWNSDNVAAG-YDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWG
..:..: . .:. : .::::..: .. . . . ::..: . . :..::::
XP_016 KEIIIHQNY---KVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWG
270 280 290 300 310 320
160 170 180 190 200 210
pF1KB6 KTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAG-GDGVRSGCQGDSGGPL
.: .:.. . ::.. .: : :.. : . . ::::: .: ...:.:::::::
XP_016 FSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCAGYKEGGKDACKGDSGGPL
330 340 350 360 370 380
220 230 240 250
pF1KB6 HCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVIASN
: :: . . :.::. ..:: ..: :.:.:. :..::
XP_016 VCKHNGMWRLVGITSW--GEGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
390 400 410 420 430
>>NP_001305325 (OMIM: 229000,612423) plasma kallikrein i (436 aa)
initn: 435 init1: 269 opt: 553 Z-score: 688.8 bits: 135.8 E(85289): 1.3e-31
Smith-Waterman score: 553; 35.1% identity (65.7% similar) in 251 aa overlap (6-251:176-419)
10 20 30
pF1KB6 MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQIS
: .. .:..:.::::... . :: :.:
NP_001 FLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVS
150 160 170 180 190 200
40 50 60 70 80 90
pF1KB6 LQYRSGGSRYHTCGGTLIRQNWVMTAAHCVD---YQKTFRVVAGDHNLSQNDGTEQYVSV
:: . ..: : :::.:: ..::.::::: : : ..:. .: :::. . ..
NP_001 LQVKLTAQR-HLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQI
210 220 230 240 250 260
100 110 120 130 140 150
pF1KB6 QKIVVHPYWNSDNVAAG-YDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWG
..:..: . .:. : .::::..: .. . . . ::..: . . :..::::
NP_001 KEIIIHQNY---KVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWG
270 280 290 300 310 320
160 170 180 190 200 210
pF1KB6 KTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAG-GDGVRSGCQGDSGGPL
.: .:.. . ::.. .: : :.. : . . ::::: .: ...:.:::::::
NP_001 FSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCAGYKEGGKDACKGDSGGPL
330 340 350 360 370 380
220 230 240 250
pF1KB6 HCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVIASN
: :: . . :.::. ..:: ..: :.:.:. :..::
NP_001 VCKHNGMWRLVGITSW--GEGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
390 400 410 420 430
>>NP_000883 (OMIM: 229000,612423) plasma kallikrein isof (638 aa)
initn: 435 init1: 269 opt: 553 Z-score: 686.5 bits: 135.9 E(85289): 1.7e-31
Smith-Waterman score: 553; 35.1% identity (65.7% similar) in 251 aa overlap (6-251:378-621)
10 20 30
pF1KB6 MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQIS
: .. .:..:.::::... . :: :.:
NP_000 FLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVS
350 360 370 380 390 400
40 50 60 70 80 90
pF1KB6 LQYRSGGSRYHTCGGTLIRQNWVMTAAHCVD---YQKTFRVVAGDHNLSQNDGTEQYVSV
:: . ..: : :::.:: ..::.::::: : : ..:. .: :::. . ..
NP_000 LQVKLTAQR-HLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQI
410 420 430 440 450 460
100 110 120 130 140 150
pF1KB6 QKIVVHPYWNSDNVAAG-YDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWG
..:..: . .:. : .::::..: .. . . . ::..: . . :..::::
NP_000 KEIIIHQNY---KVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWG
470 480 490 500 510 520
160 170 180 190 200 210
pF1KB6 KTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAG-GDGVRSGCQGDSGGPL
.: .:.. . ::.. .: : :.. : . . ::::: .: ...:.:::::::
NP_000 FSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCAGYKEGGKDACKGDSGGPL
530 540 550 560 570 580
220 230 240 250
pF1KB6 HCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVIASN
: :: . . :.::. ..:: ..: :.:.:. :..::
NP_000 VCKHNGMWRLVGITSW--GEGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
590 600 610 620 630
>>XP_011530232 (OMIM: 229000,612423) PREDICTED: plasma k (649 aa)
initn: 435 init1: 269 opt: 553 Z-score: 686.4 bits: 135.9 E(85289): 1.7e-31
Smith-Waterman score: 553; 35.1% identity (65.7% similar) in 251 aa overlap (6-251:389-632)
10 20 30
pF1KB6 MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQIS
: .. .:..:.::::... . :: :.:
XP_011 FLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVS
360 370 380 390 400 410
40 50 60 70 80 90
pF1KB6 LQYRSGGSRYHTCGGTLIRQNWVMTAAHCVD---YQKTFRVVAGDHNLSQNDGTEQYVSV
:: . ..: : :::.:: ..::.::::: : : ..:. .: :::. . ..
XP_011 LQVKLTAQR-HLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQI
420 430 440 450 460 470
100 110 120 130 140 150
pF1KB6 QKIVVHPYWNSDNVAAG-YDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWG
..:..: . .:. : .::::..: .. . . . ::..: . . :..::::
XP_011 KEIIIHQNY---KVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWG
480 490 500 510 520 530
160 170 180 190 200 210
pF1KB6 KTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAG-GDGVRSGCQGDSGGPL
.: .:.. . ::.. .: : :.. : . . ::::: .: ...:.:::::::
XP_011 FSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCAGYKEGGKDACKGDSGGPL
540 550 560 570 580 590
220 230 240 250
pF1KB6 HCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVIASN
: :: . . :.::. ..:: ..: :.:.:. :..::
XP_011 VCKHNGMWRLVGITSW--GEGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
600 610 620 630 640
258 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:28:50 2016 done: Fri Nov 4 20:28:51 2016
Total Scan time: 5.720 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]