Result of FASTA (omim) for
pFN21AE0219
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0219, 162 aa
1>>>pF1KE0219 162 - 162 aa - 162 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8841+/-0.000373; mu= 14.6137+/- 0.023
mean_var=60.9750+/-12.708, 0's: 0 Z-trim(112.8): 19 B-trim: 479 in 1/48
Lambda= 0.164247
statistics sampled from 21855 (21869) to 21855 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.256), width: 16
Scan time: 5.110
The best scores are: opt bits E(85289)
NP_001224 (OMIM: 601048) caveolin-2 isoform a [Hom ( 162) 1092 266.9 1e-71
NP_001193676 (OMIM: 601048) caveolin-2 isoform b [ ( 149) 1011 247.7 5.7e-66
NP_001193677 (OMIM: 601048) caveolin-2 isoform d [ ( 79) 522 131.6 2.6e-31
NP_001166366 (OMIM: 601047,606721,612526,615343) c ( 147) 355 92.2 3.5e-19
NP_001166368 (OMIM: 601047,606721,612526,615343) c ( 147) 355 92.2 3.5e-19
NP_001166367 (OMIM: 601047,606721,612526,615343) c ( 147) 355 92.2 3.5e-19
NP_001744 (OMIM: 601047,606721,612526,615343) cave ( 178) 355 92.3 4.1e-19
NP_937855 (OMIM: 601048) caveolin-2 isoform c [Hom ( 112) 346 90.0 1.2e-18
NP_001225 (OMIM: 123320,192600,601253,606072,60780 ( 151) 327 85.6 3.6e-17
NP_203123 (OMIM: 123320,192600,601253,606072,60780 ( 151) 327 85.6 3.6e-17
>>NP_001224 (OMIM: 601048) caveolin-2 isoform a [Homo sa (162 aa)
initn: 1092 init1: 1092 opt: 1092 Z-score: 1408.5 bits: 266.9 E(85289): 1e-71
Smith-Waterman score: 1092; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162)
10 20 30 40 50 60
pF1KE0 MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVK
70 80 90 100 110 120
130 140 150 160
pF1KE0 TCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
::::::::::::::::::::::::::::::::::::::::::
NP_001 TCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
130 140 150 160
>>NP_001193676 (OMIM: 601048) caveolin-2 isoform b [Homo (149 aa)
initn: 1011 init1: 1011 opt: 1011 Z-score: 1305.3 bits: 247.7 E(85289): 5.7e-66
Smith-Waterman score: 1011; 100.0% identity (100.0% similar) in 149 aa overlap (14-162:1-149)
10 20 30 40 50 60
pF1KE0 MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEP
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEP
10 20 30 40
70 80 90 100 110 120
pF1KE0 VTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVK
50 60 70 80 90 100
130 140 150 160
pF1KE0 TCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
::::::::::::::::::::::::::::::::::::::::::
NP_001 TCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
110 120 130 140
>>NP_001193677 (OMIM: 601048) caveolin-2 isoform d [Homo (79 aa)
initn: 522 init1: 522 opt: 522 Z-score: 683.1 bits: 131.6 E(85289): 2.6e-31
Smith-Waterman score: 522; 100.0% identity (100.0% similar) in 79 aa overlap (84-162:1-79)
60 70 80 90 100 110
pF1KE0 EDVIAEPVTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIW
::::::::::::::::::::::::::::::
NP_001 MYKFLTVFLAIPLAFIAGILFATLSCLHIW
10 20 30
120 130 140 150 160
pF1KE0 ILMPFVKTCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILMPFVKTCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
40 50 60 70
>>NP_001166366 (OMIM: 601047,606721,612526,615343) caveo (147 aa)
initn: 359 init1: 321 opt: 355 Z-score: 465.3 bits: 92.2 E(85289): 3.5e-19
Smith-Waterman score: 355; 40.8% identity (74.4% similar) in 125 aa overlap (39-162:22-146)
10 20 30 40 50 60
pF1KE0 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
.:::..::. . :. :::::::: :::::
NP_001 MADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFD
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
.: : . : ..:: .:..:.....::.:.: :: :: :: :::: ..: .:. :. .
NP_001 GIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQ
60 70 80 90 100 110
130 140 150 160
pF1KE0 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
.. ... . .. :: .::. ::.: ..:...
NP_001 CISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
120 130 140
>>NP_001166368 (OMIM: 601047,606721,612526,615343) caveo (147 aa)
initn: 359 init1: 321 opt: 355 Z-score: 465.3 bits: 92.2 E(85289): 3.5e-19
Smith-Waterman score: 355; 40.8% identity (74.4% similar) in 125 aa overlap (39-162:22-146)
10 20 30 40 50 60
pF1KE0 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
.:::..::. . :. :::::::: :::::
NP_001 MADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFD
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
.: : . : ..:: .:..:.....::.:.: :: :: :: :::: ..: .:. :. .
NP_001 GIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQ
60 70 80 90 100 110
130 140 150 160
pF1KE0 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
.. ... . .. :: .::. ::.: ..:...
NP_001 CISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
120 130 140
>>NP_001166367 (OMIM: 601047,606721,612526,615343) caveo (147 aa)
initn: 359 init1: 321 opt: 355 Z-score: 465.3 bits: 92.2 E(85289): 3.5e-19
Smith-Waterman score: 355; 40.8% identity (74.4% similar) in 125 aa overlap (39-162:22-146)
10 20 30 40 50 60
pF1KE0 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
.:::..::. . :. :::::::: :::::
NP_001 MADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFD
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
.: : . : ..:: .:..:.....::.:.: :: :: :: :::: ..: .:. :. .
NP_001 GIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQ
60 70 80 90 100 110
130 140 150 160
pF1KE0 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
.. ... . .. :: .::. ::.: ..:...
NP_001 CISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
120 130 140
>>NP_001744 (OMIM: 601047,606721,612526,615343) caveolin (178 aa)
initn: 359 init1: 321 opt: 355 Z-score: 464.1 bits: 92.3 E(85289): 4.1e-19
Smith-Waterman score: 355; 40.8% identity (74.4% similar) in 125 aa overlap (39-162:53-177)
10 20 30 40 50 60
pF1KE0 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
.:::..::. . :. :::::::: :::::
NP_001 NIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFD
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE0 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
.: : . : ..:: .:..:.....::.:.: :: :: :: :::: ..: .:. :. .
NP_001 GIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQ
90 100 110 120 130 140
130 140 150 160
pF1KE0 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
.. ... . .. :: .::. ::.: ..:...
NP_001 CISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
150 160 170
>>NP_937855 (OMIM: 601048) caveolin-2 isoform c [Homo sa (112 aa)
initn: 358 init1: 346 opt: 346 Z-score: 455.5 bits: 90.0 E(85289): 1.2e-18
Smith-Waterman score: 346; 100.0% identity (100.0% similar) in 50 aa overlap (1-50:1-50)
10 20 30 40 50 60
pF1KE0 MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEP
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKDFNAFCKDLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVK
NP_937 NGSAFSADNMEECDRCYHCSIVYERRTMLLFCQPATEPGLNTWTPGLEIGIL
70 80 90 100 110
>>NP_001225 (OMIM: 123320,192600,601253,606072,607801,61 (151 aa)
initn: 332 init1: 298 opt: 327 Z-score: 429.3 bits: 85.6 E(85289): 3.6e-17
Smith-Waterman score: 327; 39.2% identity (72.0% similar) in 125 aa overlap (39-162:26-150)
10 20 30 40 50 60
pF1KE0 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
.:::. .: . :. ::::::::: :.:::
NP_001 MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFD
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
:: :.. : .::: :..:...:..:::.. :.::: .: ::: ..: .:. :. .
NP_001 GVWKVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQ
60 70 80 90 100 110
130 140 150 160
pF1KE0 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
.. :.. .. :: ...:. ::... : ..
NP_001 CISHIYSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
120 130 140 150
>>NP_203123 (OMIM: 123320,192600,601253,606072,607801,61 (151 aa)
initn: 332 init1: 298 opt: 327 Z-score: 429.3 bits: 85.6 E(85289): 3.6e-17
Smith-Waterman score: 327; 39.2% identity (72.0% similar) in 125 aa overlap (39-162:26-150)
10 20 30 40 50 60
pF1KE0 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
.:::. .: . :. ::::::::: :.:::
NP_203 MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFD
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
:: :.. : .::: :..:...:..:::.. :.::: .: ::: ..: .:. :. .
NP_203 GVWKVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQ
60 70 80 90 100 110
130 140 150 160
pF1KE0 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
.. :.. .. :: ...:. ::... : ..
NP_203 CISHIYSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
120 130 140 150
162 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 01:49:39 2016 done: Sat Nov 5 01:49:40 2016
Total Scan time: 5.110 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]