Result of FASTA (omim) for
pFN21AE0218
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0218, 178 aa
1>>>pF1KE0218 178 - 178 aa - 178 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7096+/-0.000427; mu= 16.1100+/- 0.026
mean_var=64.9277+/-13.415, 0's: 0 Z-trim(109.9): 10 B-trim: 0 in 0/53
Lambda= 0.159169
statistics sampled from 18193 (18202) to 18193 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.593), E-opt: 0.2 (0.213), width: 16
Scan time: 4.840
The best scores are: opt bits E(85289)
NP_001744 (OMIM: 601047,606721,612526,615343) cave ( 178) 1200 284.3 7.2e-77
NP_001166366 (OMIM: 601047,606721,612526,615343) c ( 147) 989 235.7 2.4e-62
NP_001166368 (OMIM: 601047,606721,612526,615343) c ( 147) 989 235.7 2.4e-62
NP_001166367 (OMIM: 601047,606721,612526,615343) c ( 147) 989 235.7 2.4e-62
NP_203123 (OMIM: 123320,192600,601253,606072,60780 ( 151) 703 170.1 1.4e-42
NP_001225 (OMIM: 123320,192600,601253,606072,60780 ( 151) 703 170.1 1.4e-42
NP_001193676 (OMIM: 601048) caveolin-2 isoform b [ ( 149) 355 90.2 1.6e-18
NP_001224 (OMIM: 601048) caveolin-2 isoform a [Hom ( 162) 355 90.2 1.7e-18
NP_001193677 (OMIM: 601048) caveolin-2 isoform d [ ( 79) 197 53.7 8.5e-08
>>NP_001744 (OMIM: 601047,606721,612526,615343) caveolin (178 aa)
initn: 1200 init1: 1200 opt: 1200 Z-score: 1501.0 bits: 284.3 E(85289): 7.2e-77
Smith-Waterman score: 1200; 100.0% identity (100.0% similar) in 178 aa overlap (1-178:1-178)
10 20 30 40 50 60
pF1KE0 MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFA
70 80 90 100 110 120
130 140 150 160 170
pF1KE0 ILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
130 140 150 160 170
>>NP_001166366 (OMIM: 601047,606721,612526,615343) caveo (147 aa)
initn: 989 init1: 989 opt: 989 Z-score: 1240.3 bits: 235.7 E(85289): 2.4e-62
Smith-Waterman score: 989; 100.0% identity (100.0% similar) in 147 aa overlap (32-178:1-147)
10 20 30 40 50 60
pF1KE0 SGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLND
::::::::::::::::::::::::::::::
NP_001 MADELSEKQVYDAHTKEIDLVNRDPKHLND
10 20 30
70 80 90 100 110 120
pF1KE0 DVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAI
40 50 60 70 80 90
130 140 150 160 170
pF1KE0 LSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
100 110 120 130 140
>>NP_001166368 (OMIM: 601047,606721,612526,615343) caveo (147 aa)
initn: 989 init1: 989 opt: 989 Z-score: 1240.3 bits: 235.7 E(85289): 2.4e-62
Smith-Waterman score: 989; 100.0% identity (100.0% similar) in 147 aa overlap (32-178:1-147)
10 20 30 40 50 60
pF1KE0 SGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLND
::::::::::::::::::::::::::::::
NP_001 MADELSEKQVYDAHTKEIDLVNRDPKHLND
10 20 30
70 80 90 100 110 120
pF1KE0 DVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAI
40 50 60 70 80 90
130 140 150 160 170
pF1KE0 LSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
100 110 120 130 140
>>NP_001166367 (OMIM: 601047,606721,612526,615343) caveo (147 aa)
initn: 989 init1: 989 opt: 989 Z-score: 1240.3 bits: 235.7 E(85289): 2.4e-62
Smith-Waterman score: 989; 100.0% identity (100.0% similar) in 147 aa overlap (32-178:1-147)
10 20 30 40 50 60
pF1KE0 SGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLND
::::::::::::::::::::::::::::::
NP_001 MADELSEKQVYDAHTKEIDLVNRDPKHLND
10 20 30
70 80 90 100 110 120
pF1KE0 DVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAI
40 50 60 70 80 90
130 140 150 160 170
pF1KE0 LSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
100 110 120 130 140
>>NP_203123 (OMIM: 123320,192600,601253,606072,607801,61 (151 aa)
initn: 691 init1: 678 opt: 703 Z-score: 885.2 bits: 170.1 E(85289): 1.4e-42
Smith-Waterman score: 703; 64.0% identity (87.3% similar) in 150 aa overlap (32-178:2-151)
10 20 30 40 50
pF1KE0 SGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADE---LSEKQVYDAHTKEIDLVNRDPKH
::.: : . : : : :::::::::::.
NP_203 MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKN
10 20 30
60 70 80 90 100 110
pF1KE0 LNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIY
.:.:.::.::::::::: ::.::::.::.:.:::::.::: :::::.:.:.:.::.::.
NP_203 INEDIVKVDFEDVIAEPVGTYSFDGVWKVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFL
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 FAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
:: .:: :::::::::::.::::::::..::. ..: :.::: :.:.. :.... :.::.
NP_203 FACISFCHIWAVVPCIKSYLIEIQCISHIYSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
100 110 120 130 140 150
>>NP_001225 (OMIM: 123320,192600,601253,606072,607801,61 (151 aa)
initn: 691 init1: 678 opt: 703 Z-score: 885.2 bits: 170.1 E(85289): 1.4e-42
Smith-Waterman score: 703; 64.0% identity (87.3% similar) in 150 aa overlap (32-178:2-151)
10 20 30 40 50
pF1KE0 SGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADE---LSEKQVYDAHTKEIDLVNRDPKH
::.: : . : : : :::::::::::.
NP_001 MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKN
10 20 30
60 70 80 90 100 110
pF1KE0 LNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIY
.:.:.::.::::::::: ::.::::.::.:.:::::.::: :::::.:.:.:.::.::.
NP_001 INEDIVKVDFEDVIAEPVGTYSFDGVWKVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFL
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE0 FAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
:: .:: :::::::::::.::::::::..::. ..: :.::: :.:.. :.... :.::.
NP_001 FACISFCHIWAVVPCIKSYLIEIQCISHIYSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
100 110 120 130 140 150
>>NP_001193676 (OMIM: 601048) caveolin-2 isoform b [Homo (149 aa)
initn: 359 init1: 321 opt: 355 Z-score: 453.4 bits: 90.2 E(85289): 1.6e-18
Smith-Waterman score: 355; 40.8% identity (74.4% similar) in 125 aa overlap (53-177:26-149)
30 40 50 60 70 80
pF1KE0 NIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFD
.:::..::. . :. :::::::: :::::
NP_001 MDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
10 20 30 40 50
90 100 110 120 130 140
pF1KE0 GIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQ
.: : . : ..:: .:..:.....::.:.: :: :: :: :::: ..: .:. :. .
NP_001 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
60 70 80 90 100 110
150 160 170
pF1KE0 CISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
.. ... . .. :: .::. ::.: ..:...
NP_001 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
120 130 140
>>NP_001224 (OMIM: 601048) caveolin-2 isoform a [Homo sa (162 aa)
initn: 359 init1: 321 opt: 355 Z-score: 452.9 bits: 90.2 E(85289): 1.7e-18
Smith-Waterman score: 355; 40.8% identity (74.4% similar) in 125 aa overlap (53-177:39-162)
30 40 50 60 70 80
pF1KE0 NIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFD
.:::..::. . :. :::::::: :::::
NP_001 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
10 20 30 40 50 60
90 100 110 120 130 140
pF1KE0 GIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQ
.: : . : ..:: .:..:.....::.:.: :: :: :: :::: ..: .:. :. .
NP_001 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
70 80 90 100 110 120
150 160 170
pF1KE0 CISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
.. ... . .. :: .::. ::.: ..:...
NP_001 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
130 140 150 160
>>NP_001193677 (OMIM: 601048) caveolin-2 isoform d [Homo (79 aa)
initn: 189 init1: 176 opt: 197 Z-score: 261.0 bits: 53.7 E(85289): 8.5e-08
Smith-Waterman score: 197; 34.6% identity (74.4% similar) in 78 aa overlap (100-177:2-79)
70 80 90 100 110 120
pF1KE0 DVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWA
:..:.....::.:.: :: :: :: ::::
NP_001 MYKFLTVFLAIPLAFIAGILFATLSCLHIWI
10 20 30
130 140 150 160 170
pF1KE0 VVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
..: .:. :. . .. ... . .. :: .::. ::.: ..:...
NP_001 LMPFVKTCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
40 50 60 70
178 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 01:49:11 2016 done: Sat Nov 5 01:49:11 2016
Total Scan time: 4.840 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]