Result of FASTA (omim) for
pFN21AE0423
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0423, 235 aa
1>>>pF1KE0423 235 - 235 aa - 235 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3825+/-0.000352; mu= 8.8057+/- 0.022
mean_var=88.5118+/-17.051, 0's: 0 Z-trim(115.6): 17 B-trim: 85 in 1/51
Lambda= 0.136324
statistics sampled from 26221 (26232) to 26221 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.698), E-opt: 0.2 (0.308), width: 16
Scan time: 6.150
The best scores are: opt bits E(85289)
NP_003482 (OMIM: 300013,300855,309800) N-alpha-ace ( 235) 1546 313.8 1.7e-85
NP_001243049 (OMIM: 300013,300855,309800) N-alpha- ( 229) 1488 302.3 4.4e-82
NP_001243048 (OMIM: 300013,300855,309800) N-alpha- ( 220) 781 163.3 3.1e-40
NP_852668 (OMIM: 610833) N-alpha-acetyltransferase ( 166) 271 62.9 3.8e-10
NP_057184 (OMIM: 610833) N-alpha-acetyltransferase ( 178) 264 61.6 1e-09
NP_852669 (OMIM: 610833) N-alpha-acetyltransferase ( 111) 199 48.7 4.9e-06
NP_001295374 (OMIM: 610834) N-alpha-acetyltransfer ( 168) 151 39.3 0.0049
NP_079422 (OMIM: 610834) N-alpha-acetyltransferase ( 169) 151 39.3 0.0049
>>NP_003482 (OMIM: 300013,300855,309800) N-alpha-acetylt (235 aa)
initn: 1546 init1: 1546 opt: 1546 Z-score: 1656.1 bits: 313.8 E(85289): 1.7e-85
Smith-Waterman score: 1546; 100.0% identity (100.0% similar) in 235 aa overlap (1-235:1-235)
10 20 30 40 50 60
pF1KE0 MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 EEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIENKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIENKV
130 140 150 160 170 180
190 200 210 220 230
pF1KE0 ESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS
190 200 210 220 230
>>NP_001243049 (OMIM: 300013,300855,309800) N-alpha-acet (229 aa)
initn: 1496 init1: 1120 opt: 1488 Z-score: 1594.6 bits: 302.3 E(85289): 4.4e-82
Smith-Waterman score: 1488; 97.4% identity (97.4% similar) in 235 aa overlap (1-235:1-229)
10 20 30 40 50 60
pF1KE0 MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVG------
10 20 30 40 50
70 80 90 100 110 120
pF1KE0 EEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALH
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE0 LYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIENKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIENKV
120 130 140 150 160 170
190 200 210 220 230
pF1KE0 ESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS
180 190 200 210 220
>>NP_001243048 (OMIM: 300013,300855,309800) N-alpha-acet (220 aa)
initn: 1432 init1: 774 opt: 781 Z-score: 843.4 bits: 163.3 E(85289): 3.1e-40
Smith-Waterman score: 1406; 93.2% identity (93.6% similar) in 235 aa overlap (1-235:1-220)
10 20 30 40 50 60
pF1KE0 MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 EEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALH
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRK-------
70 80 90 100 110
130 140 150 160 170 180
pF1KE0 LYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIENKV
.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------RISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIENKV
120 130 140 150 160
190 200 210 220 230
pF1KE0 ESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS
170 180 190 200 210 220
>>NP_852668 (OMIM: 610833) N-alpha-acetyltransferase 20 (166 aa)
initn: 242 init1: 127 opt: 271 Z-score: 303.2 bits: 62.9 E(85289): 3.8e-10
Smith-Waterman score: 271; 35.1% identity (66.2% similar) in 148 aa overlap (12-153:1-146)
10 20 30 40 50 60
pF1KE0 MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKM
: : ::: : :.: . .:. . ::. .:: .:...::...:
NP_852 MLSQSCNLDPLTETYGIPFYLQYLAHWPEYFIVAEAPGGELMGYIMGKA
10 20 30 40
70 80 90 100 110
pF1KE0 EED-PDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAAL
: . . :::.:.:.: :::::: :::. . . : .. .:.: :: ::..:.
NP_852 EGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELLEE-ISERKGGFFVDLFVRVSNQVAV
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE0 HLYSNTLNFQISEVEPKYYA--DGE---DAYAMKRDLTQMADELRRHLELKEKGRHVVLG
..:.. :.... .. .::. .:: ::: :.. :..
NP_852 NMYKQ-LGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIIPLPHPVRPEDIE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE0 AIENKVESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDSA
>>NP_057184 (OMIM: 610833) N-alpha-acetyltransferase 20 (178 aa)
initn: 236 init1: 121 opt: 264 Z-score: 295.3 bits: 61.6 E(85289): 1e-09
Smith-Waterman score: 264; 33.8% identity (67.5% similar) in 151 aa overlap (9-153:10-158)
10 20 30 40 50
pF1KE0 MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAK
.::. ... :: : :.: . .:. . ::. .:: .:...::...:
NP_057 MTTLRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAEAPGGELMGYIMGK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 MEED-PDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAA
: . . :::.:.:.: :::::: :::. . . : .. .:.: :: ::..:
NP_057 AEGSVAREEWHGHVTALSVAPEFRRLGLAAKLMELL-EEISERKGGFFVDLFVRVSNQVA
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 LHLYSNTLNFQISEVEPKYYA--DGE---DAYAMKRDLTQMADELRRHLELKEKGRHVVL
...:.. :.... .. .::. .:: ::: :.. :..
NP_057 VNMYKQ-LGYSVYRTVIEYYSASNGEPDEDAYDMRKALSRDTEKKSIIPLPHPVRPEDIE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 GAIENKVESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDS
>>NP_852669 (OMIM: 610833) N-alpha-acetyltransferase 20 (111 aa)
initn: 204 init1: 119 opt: 199 Z-score: 229.4 bits: 48.7 E(85289): 4.9e-06
Smith-Waterman score: 199; 34.3% identity (65.7% similar) in 99 aa overlap (9-106:10-103)
10 20 30 40 50
pF1KE0 MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAK
.::. ... :: : :.: . .:. . ::. .:: .:...::...:
NP_852 MTTLRAFTCDDLFRFNNINLDPLTETYGIPFYLQYLAHWPEYFIVAEAPGGELMGYIMGK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 MEED-PDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAA
: . . :::.:.:.: :::::: :::. ..:... .:
NP_852 AEGSVAREEWHGHVTALSVAPEFRRLGLAAKLME-----LLEEISERYEESTFQGY
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 LHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIEN
>>NP_001295374 (OMIM: 610834) N-alpha-acetyltransferase (168 aa)
initn: 73 init1: 73 opt: 151 Z-score: 175.6 bits: 39.3 E(85289): 0.0049
Smith-Waterman score: 151; 23.5% identity (63.4% similar) in 153 aa overlap (1-151:5-153)
10 20 30 40 50
pF1KE0 MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYV
... .. :... .... : . .: .:. :.: : .:. .: : :: :
NP_001 MKGRIELGDVTPHNIKQLKRLNQVIFPVSYNDKFY-KDVLEVGELAKLAY-FNDIAVGAV
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNR
..... .. . .: .:. .::::.. :..... .. . . :::. ::.
NP_001 CCRVDHSQNQ-KRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 AALHLYSNTLNFQISEVEPKYYADGE--DAYAMKRDLTQMADELRRHLELKEKGRHVVLG
.:. .: . ..:.: :.. .:: : ::......:
NP_001 SAIDFYRK-FGFEIIETKKNYYKRIEPADAHVLQKNLKVPSGQNADVQKTDN
120 130 140 150 160
180 190 200 210 220 230
pF1KE0 AIENKVESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDSA
>>NP_079422 (OMIM: 610834) N-alpha-acetyltransferase 50 (169 aa)
initn: 73 init1: 73 opt: 151 Z-score: 175.5 bits: 39.3 E(85289): 0.0049
Smith-Waterman score: 151; 23.5% identity (63.4% similar) in 153 aa overlap (1-151:6-154)
10 20 30 40 50
pF1KE0 MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGY
... .. :... .... : . .: .:. :.: : .:. .: : ::
NP_079 MKGSRIELGDVTPHNIKQLKRLNQVIFPVSYNDKFY-KDVLEVGELAKLAY-FNDIAVGA
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 VLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSN
: ..... .. . .: .:. .::::.. :..... .. . . :::. ::
NP_079 VCCRVDHSQNQ-KRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 RAALHLYSNTLNFQISEVEPKYYADGE--DAYAMKRDLTQMADELRRHLELKEKGRHVVL
..:. .: . ..:.: :.. .:: : ::......:
NP_079 ESAIDFYRK-FGFEIIETKKNYYKRIEPADAHVLQKNLKVPSGQNADVQKTDN
120 130 140 150 160
180 190 200 210 220 230
pF1KE0 GAIENKVESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDS
235 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 10:43:24 2016 done: Thu Nov 3 10:43:25 2016
Total Scan time: 6.150 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]