Result of FASTA (ccds) for
pFN21AB6271
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6271, 670 aa
1>>>pF1KB6271 670 - 670 aa - 670 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4763+/-0.00082; mu= 15.4116+/- 0.050
mean_var=129.2660+/-24.653, 0's: 0 Z-trim(111.2): 76 B-trim: 0 in 0/51
Lambda= 0.112806
statistics sampled from 12135 (12210) to 12135 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.375), width: 16
Scan time: 4.390
The best scores are: opt bits E(32554)
CCDS47927.1 RHPN1 gene_id:114822|Hs108|chr8 ( 670) 4513 746.1 3.6e-215
CCDS12427.1 RHPN2 gene_id:85415|Hs108|chr19 ( 686) 1649 280.0 7.5e-75
CCDS2754.1 PTPN23 gene_id:25930|Hs108|chr3 (1636) 453 85.7 5.6e-16
>>CCDS47927.1 RHPN1 gene_id:114822|Hs108|chr8 (670 aa)
initn: 4513 init1: 4513 opt: 4513 Z-score: 3976.4 bits: 746.1 E(32554): 3.6e-215
Smith-Waterman score: 4513; 100.0% identity (100.0% similar) in 670 aa overlap (1-670:1-670)
10 20 30 40 50 60
pF1KB6 MILEERPDGAGAGEESPRLQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MILEERPDGAGAGEESPRLQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TSNNRVRETVALELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKETKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 TSNNRVRETVALELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKETKEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 DWSTPLKELISVHFGEDGASYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCFLDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 DWSTPLKELISVHFGEDGASYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCFLDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 RFLTPARSLGLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTEGAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 RFLTPARSLGLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTEGAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 RAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPASMAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 RAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPASMAP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 QDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDYVPVSWTALVHVKAEYFRSLAHYHVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 QDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDYVPVSWTALVHVKAEYFRSLAHYHVA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 MALCDGSPATEGELPTHEQVFLQPPTSSKPRGPVLPQELEERRQLGKAHLKRAILGQEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MALCDGSPATEGELPTHEQVFLQPPTSSKPRGPVLPQELEERRQLGKAHLKRAILGQEEA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 LRLHALCRVLREVDLLRAVISQTLQRSLAKYAELDREDDFCEAAEAPDIQPKTHQKPEAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LRLHALCRVLREVDLLRAVISQTLQRSLAKYAELDREDDFCEAAEAPDIQPKTHQKPEAR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 MPRLSQGKGPDIFHRLGPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSPVLIAAVIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MPRLSQGKGPDIFHRLGPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSPVLIAAVIP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 GSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAAGEAGASLQVVSLLPSSRLPSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 GSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAAGEAGASLQVVSLLPSSRLPSLG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 DRRPVLLGPRGLLRSQREHGCKTPASTWASPRPLLNWSRKAQQGKTGGCPQPCAPVKPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 DRRPVLLGPRGLLRSQREHGCKTPASTWASPRPLLNWSRKAQQGKTGGCPQPCAPVKPAP
610 620 630 640 650 660
670
pF1KB6 PSSLKHPGWP
::::::::::
CCDS47 PSSLKHPGWP
670
>>CCDS12427.1 RHPN2 gene_id:85415|Hs108|chr19 (686 aa)
initn: 1600 init1: 1405 opt: 1649 Z-score: 1457.3 bits: 280.0 E(32554): 7.5e-75
Smith-Waterman score: 1649; 42.2% identity (71.3% similar) in 658 aa overlap (20-667:23-675)
10 20 30 40 50
pF1KB6 MILEERPDGAGAGEESPRLQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENL
.::. :.: ..::..:: ..::: : ..::::::::
CCDS12 MTDALLPAAPQPLEKENDGYFRKGCNPLAQTGRSKLQNQRAALNQQILKAVRMRTGAENL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 YRATSNNRVRETVALELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKET
....:..::: : ::::.:::.::.:::::: :. .: .. :: :.:.::::::::
CCDS12 LKVATNSKVREQVRLELSFVNSDLQMLKEELEGLNISVGVYQNTEEAFTIPLIPLGLKET
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 KELDWSTPLKELISVHFGEDGASYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCF
:..:... ::..: :..::: :: :: .: :::: :::::.:.:.::: .:. :: :
CCDS12 KDVDFAVVLKDFILEHYSEDGYLYEDEIADLMDLRQACRTPSRDEAGVELLMTYFIQLGF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 LDARFLTPARSLGLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTE
...::. :.:..::.: :::::::::..:. : .::.::::: :::.::::.: ::.
CCDS12 VESRFFPPTRQMGLLFTWYDSLTGVPVSQQNLLLEKASVLFNTGALYTQIGTRCDRQTQA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 GARRAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPAS
: . :..:::::::... :...:.:.:: ::: : : .: ..:.::::: ::: .: :.
CCDS12 GLESAIDAFQRAAGVLNYLKDTFTHTPSYDMSPAMLSVLVKMMLAQAQESVFEKISLPG-
250 260 270 280 290
300 310 320 330 340 350
pF1KB6 MAPQDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDYVPVSWTALVHVKAEYFRSLAHY
.. . ...:::::.:. :. .: .:.: ::.. .: ::..:. :::... .::::
CCDS12 -IRNEFFMLVKVAQEAAKVGEVYQQLHAAMSQAPVKENIPYSWASLACVKAHHYAALAHY
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB6 HVAMALCDGS--PATEGELPTHEQVFLQPPTSSKPRG--PVLP-QELEERRQLGKAHLKR
.:. : : . :.:. . :.. :. . :.: :. .. ..::::::.::.:
CCDS12 FTAILLIDHQVKPGTDLD---HQEKCLSQLYDHMPEGLTPLATLKNDQQRRQLGKSHLRR
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB6 AILGQEEALRLHALCRVLREVDLLRAVISQTLQRSLAKYAELDREDDFCEAAEAPDIQPK
:. .::..: .::. :: ...:. :. . .:: ::. ..:::. . .::.. :
CCDS12 AMAHHEESVREASLCKKLRSIEVLQKVLCAAQERSRLTYAQHQEEDDLLNLIDAPSVVAK
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB6 THQKPEARMPRLSQGKGPDIFHRLGPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSP
:.:. . .:..:. :.:..:::::::::..:: ...: :: .:.::::..:
CCDS12 TEQEVDIILPQFSKLTVTDFFQKLGPLSVFSANKRWTPPRSIRFTAEEGDLGFTLRGNAP
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB6 VLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAAGEAGASLQVVSLLP
: . . : .:..:: .:::::::.. :.: .::. ::. :: ..:::::
CCDS12 VQVHFLDPYCSASVAGAREGDYIVSIQLVDCKWLTLSEVMKLLKSFGEDEIEMKVVSLLD
540 550 560 570 580 590
600 610 620 630 640
pF1KB6 S-SRLPSLGDRRPV-LLGPRGLLRSQREHGCKTPASTWASPR-PLLNW--SRKAQQGKTG
: : . . . : . ... . :: . : . .:.: ... :.. .
CCDS12 STSSMHNKSATYSVGMQKTYSMICLAIDDDDKTDKTKKISKKLSFLSWGTNKNRQKSAST
600 610 620 630 640 650
650 660 670
pF1KB6 GCPQPCAPVKPAPPSSLKHPGWP
: . ..: ..: :
CCDS12 LCLPSVGAARPQVKKKLPSPFSLLNSDSSWY
660 670 680
>>CCDS2754.1 PTPN23 gene_id:25930|Hs108|chr3 (1636 aa)
initn: 448 init1: 231 opt: 453 Z-score: 400.4 bits: 85.7 E(32554): 5.6e-16
Smith-Waterman score: 474; 29.6% identity (55.3% similar) in 416 aa overlap (103-506:2-370)
80 90 100 110 120 130
pF1KB6 ELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVT-VPMIPLGLKETKELDWSTPLKELIS
::: .::: : :::. .. .. .:...
CCDS27 MEAVPRMPMIWLDLKEAGDFHFQPAVKKFVL
10 20 30
140 150 160 170 180
pF1KB6 VHFGEDGASYEAEIRELEALRQ-AMRTPSRNESGLELLTAYYNQLCFLDARF-LTPARSL
..::. .:. :...:: ::: :.:.: :. : .: : .:: .:..: . ..
CCDS27 KNYGENPEAYNEELKKLELLRQNAVRVP-RDFEGCSVLRKYLGQLHYLQSRVPMGSGQEA
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB6 GLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTEGARRAMEAFQRA
.. : . ..: . .. . .:.. .:.:.::::...:: . : :: . . :: :
CCDS27 AVPVTWTEIFSGKSVAHEDIKYEQACILYNLGALHSMLGAMDKRVSEEGMKVSCTHFQCA
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB6 AGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPASMAPQDCLAQLRL
::::. :::.: .: : ::: : .::..:::::..: :: : .. .
CCDS27 AGAFAYLREHFPQAYSVDMSRQILTLNVNLMLGQAQECLLE-----KSML--DNRKSFLV
160 170 180 190 200
310 320 330 340 350 360
pF1KB6 AQEAAQVAAEYRLVHRTMAQPPVHDY---VPVSWTALVHVKAEYFRSLAHYHVAMALCDG
:. .:::. :. . :.. .: . . . .: ::..: :: ..:: :. :
CCDS27 ARISAQVVDYYKEACRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHM------G
210 220 230 240 250
370 380 390 400 410 420
pF1KB6 SPATEGELPTHEQVFLQPPTSSKPRGPVLPQELEERRQLGKAHLKRAILGQEEALRLHAL
. : : :.. :: :... :. .::..:
CCDS27 KQAEE------------------------QQKFGERV----AYFQSALDKLNEAIKLAK-
260 270 280
430 440 450 460 470 480
pF1KB6 CRVLREVDLLRAVISQTLQRSLAKYAELDREDDFC--EAAEAPD-IQPKTHQ---KPEAR
. : .. .. :.. .:: ...:: ::. : : .:: ::
CCDS27 ----GQPDTVQDALRFTMDVIGGKYNSAKKDNDFIYHEAVPALDTLQPVKGAPLVKPLPV
290 300 310 320 330 340
490 500 510 520 530 540
pF1KB6 MPRLSQGKGPDIFHRLGPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSPVLIAAVIP
: ::::: .: :... :..
CCDS27 NPTDPAVTGPDIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLD
350 360 370 380 390 400
670 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 19:01:11 2016 done: Sat Nov 5 19:01:12 2016
Total Scan time: 4.390 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]