Result of FASTA (omim) for
pFN21AB6745
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6745, 101 aa
1>>>pF1KB6745 101 - 101 aa - 101 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7337+/-0.000264; mu= 11.8371+/- 0.016
mean_var=51.0644+/-10.035, 0's: 0 Z-trim(119.7): 27 B-trim: 190 in 1/53
Lambda= 0.179480
statistics sampled from 33963 (33990) to 33963 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.399), width: 16
Scan time: 4.360
The best scores are: opt bits E(85289)
NP_002610 (OMIM: 173460) platelet factor 4 precurs ( 101) 657 176.9 5e-45
NP_002611 (OMIM: 173461) platelet factor 4 variant ( 104) 531 144.3 3.4e-35
XP_005265753 (OMIM: 173460) PREDICTED: platelet fa ( 110) 467 127.7 3.4e-30
NP_001502 (OMIM: 155730) growth-regulated alpha pr ( 107) 265 75.4 1.9e-14
NP_002985 (OMIM: 600324) C-X-C motif chemokine 5 p ( 114) 260 74.1 4.8e-14
NP_002695 (OMIM: 121010) platelet basic protein pr ( 128) 255 72.8 1.3e-13
NP_002984 (OMIM: 138965) C-X-C motif chemokine 6 p ( 114) 245 70.2 7.1e-13
NP_002080 (OMIM: 139110) C-X-C motif chemokine 2 p ( 107) 242 69.4 1.2e-12
NP_002081 (OMIM: 139111) C-X-C motif chemokine 3 p ( 107) 233 67.1 5.8e-12
NP_000575 (OMIM: 146930) interleukin-8 precursor [ ( 99) 190 55.9 1.2e-08
NP_001556 (OMIM: 147310) C-X-C motif chemokine 10 ( 98) 150 45.6 1.6e-05
NP_002407 (OMIM: 601704) C-X-C motif chemokine 9 p ( 125) 141 43.3 9.9e-05
NP_006410 (OMIM: 605149) C-X-C motif chemokine 13 ( 109) 130 40.4 0.00063
XP_006714126 (OMIM: 605149) PREDICTED: C-X-C motif ( 109) 130 40.4 0.00063
NP_002979 (OMIM: 603757) C-C motif chemokine 18 pr ( 89) 114 36.2 0.0094
>>NP_002610 (OMIM: 173460) platelet factor 4 precursor [ (101 aa)
initn: 657 init1: 657 opt: 657 Z-score: 929.4 bits: 176.9 E(85289): 5e-45
Smith-Waterman score: 657; 100.0% identity (100.0% similar) in 101 aa overlap (1-101:1-101)
10 20 30 40 50 60
pF1KB6 MSSAAGFCASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQVRPRHITSLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSSAAGFCASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQVRPRHITSLEV
10 20 30 40 50 60
70 80 90 100
pF1KB6 IKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
:::::::::::::::::::::::::::::::::::::::::
NP_002 IKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
70 80 90 100
>>NP_002611 (OMIM: 173461) platelet factor 4 variant pre (104 aa)
initn: 542 init1: 529 opt: 531 Z-score: 752.9 bits: 144.3 E(85289): 3.4e-35
Smith-Waterman score: 531; 84.6% identity (89.4% similar) in 104 aa overlap (1-101:1-104)
10 20 30 40 50
pF1KB6 MSSAAG---FCASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQVRPRHITS
::::: :.: .:::.:::::.::::: :::::::::::::::::::::::::::
NP_002 MSSAARSRLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITS
10 20 30 40 50 60
60 70 80 90 100
pF1KB6 LEVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
::::::::::::::::::::::::::::::: :::::::. :::
NP_002 LEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES
70 80 90 100
>>XP_005265753 (OMIM: 173460) PREDICTED: platelet factor (110 aa)
initn: 467 init1: 467 opt: 467 Z-score: 663.0 bits: 127.7 E(85289): 3.4e-30
Smith-Waterman score: 467; 100.0% identity (100.0% similar) in 71 aa overlap (31-101:40-110)
10 20 30 40 50 60
pF1KB6 MSSAAGFCASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQVRPRHITSLEV
::::::::::::::::::::::::::::::
XP_005 PAECLATVPGAAPAPPTWLEQLLSGGGVIYAEAEEDGDLQCLCVKTTSQVRPRHITSLEV
10 20 30 40 50 60
70 80 90 100
pF1KB6 IKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
:::::::::::::::::::::::::::::::::::::::::
XP_005 IKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
70 80 90 100 110
>>NP_001502 (OMIM: 155730) growth-regulated alpha protei (107 aa)
initn: 189 init1: 164 opt: 265 Z-score: 380.5 bits: 75.4 E(85289): 1.9e-14
Smith-Waterman score: 265; 46.6% identity (71.8% similar) in 103 aa overlap (1-101:1-103)
10 20 30 40 50
pF1KB6 MSSAAGFCA-SRPGLLFLGLLLLPLVVA-FASAEAEEDGDLQCLCVKTTSQVRPRHITSL
:. :: : : : :: ..:::: ::.: .: : .:.: :..: . ..:..: :.
NP_001 MARAALSAAPSNPRLLRVALLLLLLVAAGRRAAGASVATELRCQCLQTLQGIHPKNIQSV
10 20 30 40 50 60
60 70 80 90 100
pF1KB6 EVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
.: . :::: ...::::::::: ::. .:. ::::.:.:.:
NP_001 NVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNSDKSN
70 80 90 100
>>NP_002985 (OMIM: 600324) C-X-C motif chemokine 5 precu (114 aa)
initn: 240 init1: 199 opt: 260 Z-score: 373.1 bits: 74.1 E(85289): 4.8e-14
Smith-Waterman score: 260; 40.2% identity (75.3% similar) in 97 aa overlap (4-100:15-108)
10 20 30 40
pF1KB6 MSSAAGFCASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQ
....:: :..: :: : .: :. : .:.:.:..::.
NP_002 MSLLSSRAARVPGPSSSLCAL---LVLLLLLTQPGPIASAGPAAAVLRELRCVCLQTTQG
10 20 30 40 50
50 60 70 80 90 100
pF1KB6 VRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
:.:. :..:.:. ::.: ....:.::::..:::: .::. ::.:.:.:.
NP_002 VHPKMISNLQVFAIGPQCSKVEVVASLKNGKEICLDPEAPFLKKVIQKILDGGNKEN
60 70 80 90 100 110
>>NP_002695 (OMIM: 121010) platelet basic protein prepro (128 aa)
initn: 245 init1: 212 opt: 255 Z-score: 365.3 bits: 72.8 E(85289): 1.3e-13
Smith-Waterman score: 255; 52.9% identity (80.0% similar) in 70 aa overlap (30-99:52-121)
10 20 30 40 50
pF1KB6 MSSAAGFCASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQVRPRHITSLE
: ... ..:.:.:.:::: ..:..: :::
NP_002 VLLLLSLLLTALASSTKGQTKRNLAKGKEESLDSDLYAELRCMCIKTTSGIHPKNIQSLE
30 40 50 60 70 80
60 70 80 90 100
pF1KB6 VIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
:: : :: ...:::::.::::::: .:: :::..: :
NP_002 VIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDESAD
90 100 110 120
>>NP_002984 (OMIM: 138965) C-X-C motif chemokine 6 precu (114 aa)
initn: 238 init1: 166 opt: 245 Z-score: 352.1 bits: 70.2 E(85289): 7.1e-13
Smith-Waterman score: 245; 40.4% identity (72.7% similar) in 99 aa overlap (4-101:15-109)
10 20 30 40
pF1KB6 MSSAAGFCASRPGLLFLGLLLLPL-VVAFASAEAEEDGDLQCLCVKTTS
....:: :: : ::: : .: :. . .:.: :...:
NP_002 MSLPSSRAARVPGPSGSLCA----LLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTL
10 20 30 40 50
50 60 70 80 90 100
pF1KB6 QVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
.: :. : .:.:. :::.: ....:.::::...::: .::. ::.:.:.:.:
NP_002 RVNPKTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN
60 70 80 90 100 110
>>NP_002080 (OMIM: 139110) C-X-C motif chemokine 2 precu (107 aa)
initn: 181 init1: 156 opt: 242 Z-score: 348.3 bits: 69.4 E(85289): 1.2e-12
Smith-Waterman score: 242; 44.1% identity (72.0% similar) in 93 aa overlap (10-101:11-103)
10 20 30 40 50
pF1KB6 MSSAAGFCASRPGLLFLGLLLLPLVVAFASAE-AEEDGDLQCLCVKTTSQVRPRHITSL
: : :: ..:::: ::.: : : .:.: :..: . .. ..: :.
NP_002 MARATLSAAPSNPRLLRVALLLLLLVAASRRAAGAPLATELRCQCLQTLQGIHLKNIQSV
10 20 30 40 50 60
60 70 80 90 100
pF1KB6 EVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
.: . :::: ...:::::::.: ::. .:. ::::.:.:..
NP_002 KVKSPGPHCAQTEVIATLKNGQKACLNPASPMVKKIIEKMLKNGKSN
70 80 90 100
>>NP_002081 (OMIM: 139111) C-X-C motif chemokine 3 precu (107 aa)
initn: 176 init1: 151 opt: 233 Z-score: 335.7 bits: 67.1 E(85289): 5.8e-12
Smith-Waterman score: 233; 44.0% identity (71.4% similar) in 91 aa overlap (10-99:11-101)
10 20 30 40 50
pF1KB6 MSSAAGFCASRPGLLFLGLLLLPLVVAFASAE-AEEDGDLQCLCVKTTSQVRPRHITSL
: : :: ..:::: ::.: : : .:.: :..: . .. ..: :.
NP_002 MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAGASVVTELRCQCLQTLQGIHLKNIQSV
10 20 30 40 50 60
60 70 80 90 100
pF1KB6 EVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
.: . :::: ...:::::::.: ::. .:. .:::.:.:
NP_002 NVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
70 80 90 100
>>NP_000575 (OMIM: 146930) interleukin-8 precursor [Homo (99 aa)
initn: 139 init1: 131 opt: 190 Z-score: 276.1 bits: 55.9 E(85289): 1.2e-08
Smith-Waterman score: 190; 29.3% identity (71.7% similar) in 92 aa overlap (10-100:3-94)
10 20 30 40 50
pF1KB6 MSSAAGFCASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQ-VRPRHITSLE
:. .. .:. .:. .. ... . .:.: :.:: :. .:. : :.
NP_000 MTSKLAVALLAAFLISAALCEGAVLPRSAKELRCQCIKTYSKPFHPKFIKELR
10 20 30 40 50
60 70 80 90 100
pF1KB6 VIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
::..:::: ....:. :..::..::: . .....:.:.
NP_000 VIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS
60 70 80 90
101 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:17:03 2016 done: Sat Nov 5 18:17:03 2016
Total Scan time: 4.360 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]