Result of FASTA (omim) for
pFN21AB0945
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0945, 170 aa
1>>>pF1KB0945 170 - 170 aa - 170 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6923+/-0.000447; mu= 11.2195+/- 0.028
mean_var=116.7858+/-22.535, 0's: 0 Z-trim(112.8): 240 B-trim: 52 in 2/52
Lambda= 0.118680
statistics sampled from 21499 (21886) to 21499 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.631), E-opt: 0.2 (0.257), width: 16
Scan time: 5.260
The best scores are: opt bits E(85289)
NP_000936 (OMIM: 601302) calcineurin subunit B typ ( 170) 1123 203.0 2e-52
NP_671709 (OMIM: 613821) calcineurin subunit B typ ( 173) 950 173.4 1.6e-43
NP_008819 (OMIM: 114180,614916,616247) calmodulin ( 149) 302 62.3 3.7e-10
NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149) 302 62.3 3.7e-10
NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149) 302 62.3 3.7e-10
NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149) 302 62.3 3.7e-10
XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150) 296 61.3 7.6e-10
NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197) 296 61.4 9.1e-10
NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149) 289 60.1 1.7e-09
NP_009167 (OMIM: 606988) calcineurin B homologous ( 195) 289 60.2 2.1e-09
NP_001245288 (OMIM: 600207) hippocalcin-like prote ( 193) 272 57.3 1.6e-08
XP_016859441 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 272 57.3 1.6e-08
NP_002140 (OMIM: 600207) hippocalcin-like protein ( 193) 272 57.3 1.6e-08
XP_016859440 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 272 57.3 1.6e-08
XP_011508650 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 272 57.3 1.6e-08
XP_011508648 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 272 57.3 1.6e-08
XP_005246219 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 272 57.3 1.6e-08
XP_005246218 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 272 57.3 1.6e-08
XP_005246220 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 272 57.3 1.6e-08
NP_001245286 (OMIM: 600207) hippocalcin-like prote ( 193) 272 57.3 1.6e-08
XP_016859442 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 272 57.3 1.6e-08
XP_016859439 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 272 57.3 1.6e-08
NP_001245287 (OMIM: 600207) hippocalcin-like prote ( 193) 272 57.3 1.6e-08
XP_005246217 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 272 57.3 1.6e-08
NP_602293 (OMIM: 600207) hippocalcin-like protein ( 193) 272 57.3 1.6e-08
XP_011508649 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 272 57.3 1.6e-08
NP_001316852 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 263 55.5 3.2e-08
NP_001292555 (OMIM: 114182,616249) calmodulin isof ( 113) 263 55.5 3.2e-08
NP_001292554 (OMIM: 114182,616249) calmodulin isof ( 113) 263 55.5 3.2e-08
NP_001316855 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 263 55.5 3.2e-08
NP_001316854 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 263 55.5 3.2e-08
NP_001316853 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 263 55.5 3.2e-08
NP_001316850 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 263 55.5 3.2e-08
NP_001258817 (OMIM: 605564,609439,614869) calcium ( 144) 263 55.6 3.7e-08
XP_006720437 (OMIM: 605564,609439,614869) PREDICTE ( 144) 263 55.6 3.7e-08
XP_011515636 (OMIM: 606722) PREDICTED: neurocalcin ( 193) 264 55.9 4e-08
NP_001035715 (OMIM: 606722) neurocalcin-delta [Hom ( 193) 264 55.9 4e-08
XP_016869391 (OMIM: 606722) PREDICTED: neurocalcin ( 193) 264 55.9 4e-08
NP_001035718 (OMIM: 606722) neurocalcin-delta [Hom ( 193) 264 55.9 4e-08
NP_001035719 (OMIM: 606722) neurocalcin-delta [Hom ( 193) 264 55.9 4e-08
XP_011515635 (OMIM: 606722) PREDICTED: neurocalcin ( 193) 264 55.9 4e-08
NP_001035720 (OMIM: 606722) neurocalcin-delta [Hom ( 193) 264 55.9 4e-08
XP_016869390 (OMIM: 606722) PREDICTED: neurocalcin ( 193) 264 55.9 4e-08
NP_114430 (OMIM: 606722) neurocalcin-delta [Homo s ( 193) 264 55.9 4e-08
NP_001035714 (OMIM: 606722) neurocalcin-delta [Hom ( 193) 264 55.9 4e-08
NP_001035717 (OMIM: 606722) neurocalcin-delta [Hom ( 193) 264 55.9 4e-08
XP_011515634 (OMIM: 606722) PREDICTED: neurocalcin ( 193) 264 55.9 4e-08
XP_011515637 (OMIM: 606722) PREDICTED: neurocalcin ( 193) 264 55.9 4e-08
NP_001035716 (OMIM: 606722) neurocalcin-delta [Hom ( 193) 264 55.9 4e-08
XP_011519463 (OMIM: 605564,609439,614869) PREDICTE ( 167) 263 55.7 4.1e-08
>>NP_000936 (OMIM: 601302) calcineurin subunit B type 1 (170 aa)
initn: 1123 init1: 1123 opt: 1123 Z-score: 1062.3 bits: 203.0 E(85289): 2e-52
Smith-Waterman score: 1123; 100.0% identity (100.0% similar) in 170 aa overlap (1-170:1-170)
10 20 30 40 50 60
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVID
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 IFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV
70 80 90 100 110 120
130 140 150 160 170
pF1KB0 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
130 140 150 160 170
>>NP_671709 (OMIM: 613821) calcineurin subunit B type 2 (173 aa)
initn: 1026 init1: 950 opt: 950 Z-score: 902.2 bits: 173.4 E(85289): 1.6e-43
Smith-Waterman score: 950; 84.7% identity (92.9% similar) in 170 aa overlap (1-170:4-173)
10 20 30 40 50
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQR
:::::::: ::::::: :::::::.::::::::.:::::::::::::::..::::.:
NP_671 MSTMGNEASYPAEMCSHFDNDEIKRLGRRFKKLDLDKSGSLSVEEFMSLPELRHNPLVRR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB0 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK
:::.:::::.::::::::: :.::::::::.:::::::: ::::::::::::::::::::
NP_671 VIDVFDTDGDGEVDFKEFILGTSQFSVKGDEEQKLRFAFSIYDMDKDGYISNGELFQVLK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB0 MMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
::::::: : ::::.:::::: ::::::.:::::: ::: :.::::.:. :
NP_671 MMVGNNLTDWQLQQLVDKTIIILDKDGDGKISFEEFSAVVRDLEIHKKLVLIV
130 140 150 160 170
>>NP_008819 (OMIM: 114180,614916,616247) calmodulin [Hom (149 aa)
initn: 253 init1: 176 opt: 302 Z-score: 303.3 bits: 62.3 E(85289): 3.7e-10
Smith-Waterman score: 302; 35.4% identity (68.7% similar) in 147 aa overlap (11-153:1-142)
10 20 30 40 50
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQ
: ... ..: .. . :. .: :..:.....:. . . : ::: .:
NP_008 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL
.:. :.:::: .:: ::. ... :.:...: :::..: : .:::: .:: .:.
NP_008 DMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
. :..: : . ::. : .:: ::::....:::
NP_008 TNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK
120 130 140
>>NP_001734 (OMIM: 114182,616249) calmodulin isoform 2 [ (149 aa)
initn: 253 init1: 176 opt: 302 Z-score: 303.3 bits: 62.3 E(85289): 3.7e-10
Smith-Waterman score: 302; 35.4% identity (68.7% similar) in 147 aa overlap (11-153:1-142)
10 20 30 40 50
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQ
: ... ..: .. . :. .: :..:.....:. . . : ::: .:
NP_001 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL
.:. :.:::: .:: ::. ... :.:...: :::..: : .:::: .:: .:.
NP_001 DMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
. :..: : . ::. : .:: ::::....:::
NP_001 TNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK
120 130 140
>>NP_001316851 (OMIM: 114183) calmodulin isoform 1 [Homo (149 aa)
initn: 253 init1: 176 opt: 302 Z-score: 303.3 bits: 62.3 E(85289): 3.7e-10
Smith-Waterman score: 302; 35.4% identity (68.7% similar) in 147 aa overlap (11-153:1-142)
10 20 30 40 50
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQ
: ... ..: .. . :. .: :..:.....:. . . : ::: .:
NP_001 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL
.:. :.:::: .:: ::. ... :.:...: :::..: : .:::: .:: .:.
NP_001 DMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
. :..: : . ::. : .:: ::::....:::
NP_001 TNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK
120 130 140
>>NP_005175 (OMIM: 114183) calmodulin isoform 1 [Homo sa (149 aa)
initn: 253 init1: 176 opt: 302 Z-score: 303.3 bits: 62.3 E(85289): 3.7e-10
Smith-Waterman score: 302; 35.4% identity (68.7% similar) in 147 aa overlap (11-153:1-142)
10 20 30 40 50
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQ
: ... ..: .. . :. .: :..:.....:. . . : ::: .:
NP_005 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL
.:. :.:::: .:: ::. ... :.:...: :::..: : .:::: .:: .:.
NP_005 DMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
. :..: : . ::. : .:: ::::....:::
NP_005 TNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK
120 130 140
>>XP_006720321 (OMIM: 114180,614916,616247) PREDICTED: c (150 aa)
initn: 253 init1: 176 opt: 296 Z-score: 297.7 bits: 61.3 E(85289): 7.6e-10
Smith-Waterman score: 296; 36.4% identity (69.3% similar) in 140 aa overlap (18-153:9-143)
10 20 30 40 50
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---VQ
..: .. . :. .: :..:.....:. . . : ::: .:
XP_006 MQADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 RVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL
.:. :.:::: .:: ::. ... :.:...: :::..: : .:::: .:: .:.
XP_006 DMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB0 KMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
. :..: : . ::. : .:: ::::....:::
XP_006 TNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK
120 130 140 150
>>NP_001292553 (OMIM: 114182,616249) calmodulin isoform (197 aa)
initn: 253 init1: 176 opt: 296 Z-score: 296.3 bits: 61.4 E(85289): 9.1e-10
Smith-Waterman score: 296; 36.4% identity (69.3% similar) in 140 aa overlap (18-153:56-190)
10 20 30 40
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-L
..: .. . :. .: :..:.....:. . .
NP_001 RKPVALAAWLALYIASHFAQQPCKADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVM
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB0 PELQQNPL---VQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDK
: ::: .: .:. :.:::: .:: ::. ... :.:...: :::..: :
NP_001 RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDG
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB0 DGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIH
.:::: .:: .:. . :..: : . ::. : .:: ::::....:::
NP_001 NGYISAAELRHVMTNL-GEKLTDEE----VDEMIREADIDGDGQVNYEEFVQMMTAK
150 160 170 180 190
170
pF1KB0 KKMVVDV
>>NP_005176 (OMIM: 114184) calmodulin-like protein 3 [Ho (149 aa)
initn: 308 init1: 160 opt: 289 Z-score: 291.3 bits: 60.1 E(85289): 1.7e-09
Smith-Waterman score: 289; 34.2% identity (67.8% similar) in 152 aa overlap (11-157:1-146)
10 20 30 40 50
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPLVQRVI
: ... ... .. . :. .: :..: ....:. . . : ::: ..
NP_005 MADQLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELR
10 20 30 40 50
60 70 80 90 100 110
pF1KB0 DIF---DTDGNGEVDFKEFIEGVSQFSVKG-DKEQKLRFAFRIYDMDKDGYISNGELFQV
:.. : :::: ::: ::. :. ..: :.:...: :::..: : .:..: .:: .:
NP_005 DMMSEIDRDGNGTVDFPEFL-GMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHV
60 70 80 90 100
120 130 140 150 160 170
pF1KB0 LKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
. . :..:.: . ::. : :: ::::....::: :.
NP_005 MTRL-GEKLSDEE----VDEMIRAADTDGDGQVNYEEFVRVLVSK
110 120 130 140
>>NP_009167 (OMIM: 606988) calcineurin B homologous prot (195 aa)
initn: 436 init1: 287 opt: 289 Z-score: 289.9 bits: 60.2 E(85289): 2.1e-09
Smith-Waterman score: 431; 43.2% identity (69.8% similar) in 169 aa overlap (15-168:23-191)
10 20 30 40 50
pF1KB0 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQN
:. ..: :: .:: .:: ..:.:: :.:. .::: :
NP_009 MGSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAIN
10 20 30 40 50 60
60 70 80 90
pF1KB0 PLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQ---------------KLRFAFR
:: .:.:. : .:. .:.:. :.. ...: :.:. ::.::::
NP_009 PLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFR
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB0 IYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV
.::.::: :: ::.:::.:::: :..: :: .:.:.:: .::.:::. ::: :: :.
NP_009 LYDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVL
130 140 150 160 170 180
160 170
pF1KB0 GGLDIHKKMVVDV
.:...:: .
NP_009 EKVDVEQKMSIRFLH
190
170 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:52:57 2016 done: Sat Nov 5 17:52:58 2016
Total Scan time: 5.260 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]