Result of FASTA (omim) for
pFN21AB0903
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0903, 90 aa
1>>>pF1KB0903 90 - 90 aa - 90 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9083+/-0.000268; mu= 10.5186+/- 0.017
mean_var=57.5768+/-11.183, 0's: 0 Z-trim(118.4): 58 B-trim: 42 in 1/59
Lambda= 0.169025
statistics sampled from 31232 (31303) to 31232 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.367), width: 16
Scan time: 4.250
The best scores are: opt bits E(85289)
NP_067546 (OMIM: 605354) caspase recruitment domai ( 90) 600 153.6 3.9e-38
NP_443121 (OMIM: 615680) caspase recruitment domai ( 97) 329 87.6 3.3e-18
NP_001017534 (OMIM: 615680) caspase recruitment do ( 197) 329 87.7 5.9e-18
XP_011540885 (OMIM: 615680) PREDICTED: caspase rec ( 265) 317 84.9 5.7e-17
NP_001244048 (OMIM: 147678) caspase-1 isoform beta ( 383) 315 84.5 1.1e-16
NP_001214 (OMIM: 147678) caspase-1 isoform beta pr ( 383) 315 84.5 1.1e-16
NP_150634 (OMIM: 147678) caspase-1 isoform alpha p ( 404) 315 84.5 1.1e-16
NP_001244047 (OMIM: 147678) caspase-1 isoform alph ( 404) 315 84.5 1.1e-16
NP_001007233 (OMIM: 609490) caspase recruitment do ( 110) 302 81.0 3.5e-16
XP_011541140 (OMIM: 609490) PREDICTED: caspase rec ( 125) 302 81.0 3.9e-16
XP_016873885 (OMIM: 147678) PREDICTED: caspase-1 i ( 374) 188 53.5 2.2e-07
XP_016873884 (OMIM: 147678) PREDICTED: caspase-1 i ( 380) 188 53.5 2.3e-07
XP_016873882 (OMIM: 147678) PREDICTED: caspase-1 i ( 401) 188 53.5 2.4e-07
XP_016873883 (OMIM: 147678) PREDICTED: caspase-1 i ( 401) 188 53.5 2.4e-07
>>NP_067546 (OMIM: 605354) caspase recruitment domain-co (90 aa)
initn: 600 init1: 600 opt: 600 Z-score: 805.6 bits: 153.6 E(85289): 3.9e-38
Smith-Waterman score: 600; 100.0% identity (100.0% similar) in 90 aa overlap (1-90:1-90)
10 20 30 40 50 60
pF1KB0 MADQLLRKKRRIFIHSVGAGTINALLDCLLEDEVISQEDMNKVRDENDTVMDKARVLIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 MADQLLRKKRRIFIHSVGAGTINALLDCLLEDEVISQEDMNKVRDENDTVMDKARVLIDL
10 20 30 40 50 60
70 80 90
pF1KB0 VTGKGPKSCCKFIKHLCEEDPQLASKMGLH
::::::::::::::::::::::::::::::
NP_067 VTGKGPKSCCKFIKHLCEEDPQLASKMGLH
70 80 90
>>NP_443121 (OMIM: 615680) caspase recruitment domain-co (97 aa)
initn: 329 init1: 329 opt: 329 Z-score: 447.9 bits: 87.6 E(85289): 3.3e-18
Smith-Waterman score: 329; 56.2% identity (80.9% similar) in 89 aa overlap (1-89:1-89)
10 20 30 40 50 60
pF1KB0 MADQLLRKKRRIFIHSVGAGTINALLDCLLEDEVISQEDMNKVRDENDTVMDKARVLIDL
:::..:..::..::::.: ::::.::: ::. .:..::.:.::. :: :::::.:.:::
NP_443 MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS
10 20 30 40 50 60
70 80 90
pF1KB0 VTGKGPKSCCKFIKHLCEEDPQLASKMGLH
: :: ..: : ..:::: :: .::
NP_443 VIPKGAQACQICITYICEEDSYLAETLGLSAGPIPGN
70 80 90
>>NP_001017534 (OMIM: 615680) caspase recruitment domain (197 aa)
initn: 329 init1: 329 opt: 329 Z-score: 443.4 bits: 87.7 E(85289): 5.9e-18
Smith-Waterman score: 329; 56.2% identity (80.9% similar) in 89 aa overlap (1-89:1-89)
10 20 30 40 50 60
pF1KB0 MADQLLRKKRRIFIHSVGAGTINALLDCLLEDEVISQEDMNKVRDENDTVMDKARVLIDL
:::..:..::..::::.: ::::.::: ::. .:..::.:.::. :: :::::.:.:::
NP_001 MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDS
10 20 30 40 50 60
70 80 90
pF1KB0 VTGKGPKSCCKFIKHLCEEDPQLASKMGLH
: :: ..: : ..:::: :: .::
NP_001 VIPKGAQACQICITYICEEDSYLAETLGLSAALQAVQDNPAMPTCSSPEGRIKLCFLEDA
70 80 90 100 110 120
>>XP_011540885 (OMIM: 615680) PREDICTED: caspase recruit (265 aa)
initn: 317 init1: 317 opt: 317 Z-score: 425.6 bits: 84.9 E(85289): 5.7e-17
Smith-Waterman score: 317; 55.2% identity (80.5% similar) in 87 aa overlap (3-89:71-157)
10 20 30
pF1KB0 MADQLLRKKRRIFIHSVGAGTINALLDCLLED
:..:..::..::::.: ::::.::: ::.
XP_011 LLFQEQVPGKKELWKGLALLEAIISICGSLDKVLKEKRKLFIHSMGEGTINGLLDELLQT
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB0 EVISQEDMNKVRDENDTVMDKARVLIDLVTGKGPKSCCKFIKHLCEEDPQLASKMGLH
.:..::.:.::. :: :::::.:.::: : :: ..: : ..:::: :: .::
XP_011 RVLNQEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAETLGLSAA
110 120 130 140 150 160
XP_011 LQAVQDNPAMPTCSSPEGRIKLCFLEDAQRIWKQKLQRCHVQNTIIKWSERYTSGSFEMQ
170 180 190 200 210 220
>>NP_001244048 (OMIM: 147678) caspase-1 isoform beta pre (383 aa)
initn: 315 init1: 315 opt: 315 Z-score: 420.6 bits: 84.5 E(85289): 1.1e-16
Smith-Waterman score: 315; 53.9% identity (82.0% similar) in 89 aa overlap (1-89:1-89)
10 20 30 40 50 60
pF1KB0 MADQLLRKKRRIFIHSVGAGTINALLDCLLEDEVISQEDMNKVRDENDTVMDKARVLIDL
:::..:..::..::.:.: ::::.::: ::. .:...:.:.::. :: :::::.:.:::
NP_001 MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDS
10 20 30 40 50 60
70 80 90
pF1KB0 VTGKGPKSCCKFIKHLCEEDPQLASKMGLH
: :: ..: : ..:::: ::. .::
NP_001 VIPKGAQACQICITYICEEDSYLAGTLGLSAAPQAVQDNPAMPTSSGSEGNVKLCSLEEA
70 80 90 100 110 120
>>NP_001214 (OMIM: 147678) caspase-1 isoform beta precur (383 aa)
initn: 315 init1: 315 opt: 315 Z-score: 420.6 bits: 84.5 E(85289): 1.1e-16
Smith-Waterman score: 315; 53.9% identity (82.0% similar) in 89 aa overlap (1-89:1-89)
10 20 30 40 50 60
pF1KB0 MADQLLRKKRRIFIHSVGAGTINALLDCLLEDEVISQEDMNKVRDENDTVMDKARVLIDL
:::..:..::..::.:.: ::::.::: ::. .:...:.:.::. :: :::::.:.:::
NP_001 MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDS
10 20 30 40 50 60
70 80 90
pF1KB0 VTGKGPKSCCKFIKHLCEEDPQLASKMGLH
: :: ..: : ..:::: ::. .::
NP_001 VIPKGAQACQICITYICEEDSYLAGTLGLSAAPQAVQDNPAMPTSSGSEGNVKLCSLEEA
70 80 90 100 110 120
>>NP_150634 (OMIM: 147678) caspase-1 isoform alpha precu (404 aa)
initn: 315 init1: 315 opt: 315 Z-score: 420.3 bits: 84.5 E(85289): 1.1e-16
Smith-Waterman score: 315; 53.9% identity (82.0% similar) in 89 aa overlap (1-89:1-89)
10 20 30 40 50 60
pF1KB0 MADQLLRKKRRIFIHSVGAGTINALLDCLLEDEVISQEDMNKVRDENDTVMDKARVLIDL
:::..:..::..::.:.: ::::.::: ::. .:...:.:.::. :: :::::.:.:::
NP_150 MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDS
10 20 30 40 50 60
70 80 90
pF1KB0 VTGKGPKSCCKFIKHLCEEDPQLASKMGLH
: :: ..: : ..:::: ::. .::
NP_150 VIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDN
70 80 90 100 110 120
>>NP_001244047 (OMIM: 147678) caspase-1 isoform alpha pr (404 aa)
initn: 315 init1: 315 opt: 315 Z-score: 420.3 bits: 84.5 E(85289): 1.1e-16
Smith-Waterman score: 315; 53.9% identity (82.0% similar) in 89 aa overlap (1-89:1-89)
10 20 30 40 50 60
pF1KB0 MADQLLRKKRRIFIHSVGAGTINALLDCLLEDEVISQEDMNKVRDENDTVMDKARVLIDL
:::..:..::..::.:.: ::::.::: ::. .:...:.:.::. :: :::::.:.:::
NP_001 MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDS
10 20 30 40 50 60
70 80 90
pF1KB0 VTGKGPKSCCKFIKHLCEEDPQLASKMGLH
: :: ..: : ..:::: ::. .::
NP_001 VIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDN
70 80 90 100 110 120
>>NP_001007233 (OMIM: 609490) caspase recruitment domain (110 aa)
initn: 302 init1: 302 opt: 302 Z-score: 411.5 bits: 81.0 E(85289): 3.5e-16
Smith-Waterman score: 302; 55.1% identity (78.7% similar) in 89 aa overlap (1-89:1-89)
10 20 30 40 50 60
pF1KB0 MADQLLRKKRRIFIHSVGAGTINALLDCLLEDEVISQEDMNKVRDENDTVMDKARVLIDL
:::..:..::. ::.::: ::::.:: ::: .:.:::... :. :: :::::::.:.:
NP_001 MADKVLKEKRKQFIRSVGEGTINGLLGELLETRVLSQEEIEIVKCENATVMDKARALLDS
10 20 30 40 50 60
70 80 90
pF1KB0 VTGKGPKSCCKFIKHLCEEDPQLASKMGLH
: :: .: : ..:::: .::. .::
NP_001 VIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLTTQDSQIVLPS
70 80 90 100 110
>>XP_011541140 (OMIM: 609490) PREDICTED: caspase recruit (125 aa)
initn: 302 init1: 302 opt: 302 Z-score: 410.7 bits: 81.0 E(85289): 3.9e-16
Smith-Waterman score: 302; 55.1% identity (78.7% similar) in 89 aa overlap (1-89:16-104)
10 20 30 40
pF1KB0 MADQLLRKKRRIFIHSVGAGTINALLDCLLEDEVISQEDMNKVRD
:::..:..::. ::.::: ::::.:: ::: .:.:::... :.
XP_011 MLSVSAYTRREERKAMADKVLKEKRKQFIRSVGEGTINGLLGELLETRVLSQEEIEIVKC
10 20 30 40 50 60
50 60 70 80 90
pF1KB0 ENDTVMDKARVLIDLVTGKGPKSCCKFIKHLCEEDPQLASKMGLH
:: :::::::.:.: : :: .: : ..:::: .::. .::
XP_011 ENATVMDKARALLDSVIRKGAPACQICITYICEEDSHLAGTLGLSAGPTSGNHLTTQDSQ
70 80 90 100 110 120
XP_011 IVLPS
90 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:06:40 2016 done: Sat Nov 5 17:06:41 2016
Total Scan time: 4.250 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]