Result of FASTA (omim) for
pFN21AB9993
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9993, 584 aa
1>>>pF1KB9993 584 - 584 aa - 584 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6671+/-0.00034; mu= 6.4644+/- 0.021
mean_var=289.0632+/-60.124, 0's: 0 Z-trim(123.0): 112 B-trim: 0 in 0/59
Lambda= 0.075436
statistics sampled from 41980 (42133) to 41980 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.794), E-opt: 0.2 (0.494), width: 16
Scan time: 13.220
The best scores are: opt bits E(85289)
NP_001123512 (OMIM: 600560) SHC-transforming prote ( 584) 4040 453.2 1.1e-126
NP_892113 (OMIM: 600560) SHC-transforming protein ( 583) 4023 451.3 3.9e-126
XP_005245506 (OMIM: 600560) PREDICTED: SHC-transfo ( 598) 3746 421.2 4.8e-117
XP_011508195 (OMIM: 600560) PREDICTED: SHC-transfo ( 592) 3403 383.9 8.2e-106
NP_003020 (OMIM: 600560) SHC-transforming protein ( 474) 3277 370.1 9.5e-102
NP_001123513 (OMIM: 600560) SHC-transforming prote ( 473) 3260 368.2 3.4e-101
XP_005245508 (OMIM: 600560) PREDICTED: SHC-transfo ( 488) 2983 338.1 4.1e-92
NP_001189788 (OMIM: 600560) SHC-transforming prote ( 428) 2933 332.6 1.6e-90
XP_011508200 (OMIM: 600560) PREDICTED: SHC-transfo ( 432) 2580 294.2 6.1e-79
XP_011508194 (OMIM: 600560) PREDICTED: SHC-transfo ( 593) 2281 261.8 4.7e-69
XP_016857570 (OMIM: 600560) PREDICTED: SHC-transfo ( 566) 2213 254.3 7.7e-67
XP_016857572 (OMIM: 600560) PREDICTED: SHC-transfo ( 455) 2196 252.4 2.4e-66
XP_011508199 (OMIM: 600560) PREDICTED: SHC-transfo ( 465) 1805 209.8 1.6e-53
XP_011508196 (OMIM: 600560) PREDICTED: SHC-transfo ( 575) 1805 209.9 1.8e-53
XP_016857571 (OMIM: 600560) PREDICTED: SHC-transfo ( 565) 1710 199.6 2.3e-50
NP_036567 (OMIM: 605217) SHC-transforming protein ( 582) 1632 191.1 8.5e-48
XP_011526195 (OMIM: 605217) PREDICTED: SHC-transfo ( 594) 1499 176.7 1.9e-43
XP_011526198 (OMIM: 605217) PREDICTED: SHC-transfo ( 437) 1233 147.6 8.3e-35
XP_016882056 (OMIM: 605217) PREDICTED: SHC-transfo ( 437) 1233 147.6 8.3e-35
NP_058544 (OMIM: 605263) SHC-transforming protein ( 594) 1201 144.2 1.1e-33
XP_011517087 (OMIM: 605263) PREDICTED: SHC-transfo ( 598) 1190 143.0 2.6e-33
XP_011526197 (OMIM: 605217) PREDICTED: SHC-transfo ( 537) 1174 141.2 8.1e-33
XP_011526196 (OMIM: 605217) PREDICTED: SHC-transfo ( 549) 1174 141.3 8.2e-33
XP_011517088 (OMIM: 605263) PREDICTED: SHC-transfo ( 452) 949 116.7 1.7e-25
XP_016870299 (OMIM: 605263) PREDICTED: SHC-transfo ( 307) 735 93.2 1.4e-18
>>NP_001123512 (OMIM: 600560) SHC-transforming protein 1 (584 aa)
initn: 4040 init1: 4040 opt: 4040 Z-score: 2395.4 bits: 453.2 E(85289): 1.1e-126
Smith-Waterman score: 4040; 100.0% identity (100.0% similar) in 584 aa overlap (1-584:1-584)
10 20 30 40 50 60
pF1KB9 MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 GGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 ELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 AEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPE
490 500 510 520 530 540
550 560 570 580
pF1KB9 GVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL
::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL
550 560 570 580
>>NP_892113 (OMIM: 600560) SHC-transforming protein 1 is (583 aa)
initn: 2904 init1: 2904 opt: 4023 Z-score: 2385.4 bits: 451.3 E(85289): 3.9e-126
Smith-Waterman score: 4023; 99.8% identity (99.8% similar) in 584 aa overlap (1-584:1-583)
10 20 30 40 50 60
pF1KB9 MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 GGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_892 GGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCP-GR
370 380 390 400 410
430 440 450 460 470 480
pF1KB9 ELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 ELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSM
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB9 AEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 AEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPE
480 490 500 510 520 530
550 560 570 580
pF1KB9 GVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL
::::::::::::::::::::::::::::::::::::::::::::
NP_892 GVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL
540 550 560 570 580
>>XP_005245506 (OMIM: 600560) PREDICTED: SHC-transformin (598 aa)
initn: 2904 init1: 2904 opt: 3746 Z-score: 2222.4 bits: 421.2 E(85289): 4.8e-117
Smith-Waterman score: 3746; 99.8% identity (99.8% similar) in 543 aa overlap (1-543:1-542)
10 20 30 40 50 60
pF1KB9 MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 GGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_005 GGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCP-GR
370 380 390 400 410
430 440 450 460 470 480
pF1KB9 ELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSM
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB9 AEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPE
480 490 500 510 520 530
550 560 570 580
pF1KB9 GVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL
:::
XP_005 GVVSVAEVWVRGGKKEGTVPYSVSLFLPSLLCRHSRWAAVYGPLLLFKVSGIFLQRLIP
540 550 560 570 580 590
>>XP_011508195 (OMIM: 600560) PREDICTED: SHC-transformin (592 aa)
initn: 3385 init1: 2235 opt: 3403 Z-score: 2020.7 bits: 383.9 E(85289): 8.2e-106
Smith-Waterman score: 3995; 98.3% identity (98.3% similar) in 593 aa overlap (1-584:1-592)
10 20 30 40 50 60
pF1KB9 MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 ISTIGQAFELRFKQYLRNPPKLVTPHD---------RMAGFDGSAWDEEEEEPPDHQYYN
::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_011 ISTIGQAFELRFKQYLRNPPKLVTPHDSHSFTVLSLRMAGFDGSAWDEEEEEPPDHQYYN
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB9 DFPGKEPPLGGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFPGKEPPLGGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB9 PPPPCPAGRELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRV
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPPCP-GRELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRV
430 440 450 460 470
480 490 500 510 520 530
pF1KB9 PPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQP
480 490 500 510 520 530
540 550 560 570 580
pF1KB9 KHLLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHLLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL
540 550 560 570 580 590
>>NP_003020 (OMIM: 600560) SHC-transforming protein 1 is (474 aa)
initn: 3277 init1: 3277 opt: 3277 Z-score: 1947.7 bits: 370.1 E(85289): 9.5e-102
Smith-Waterman score: 3277; 100.0% identity (100.0% similar) in 474 aa overlap (111-584:1-474)
90 100 110 120 130 140
pF1KB9 KGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSF
::::::::::::::::::::::::::::::
NP_003 MNKLSGGGGRRTRVEGGQLGGEEWTRHGSF
10 20 30
150 160 170 180 190 200
pF1KB9 VNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVP
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB9 GAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSI
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB9 SFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPP
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB9 KLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAARPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAARPT
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB9 APNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGRELFDDPSYVNVQNLDKARQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 APNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGRELFDDPSYVNVQNLDKARQA
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB9 VGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMAEQLRGEPWFHGKLSRREAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMAEQLRGEPWFHGKLSRREAE
340 350 360 370 380 390
510 520 530 540 550 560
pF1KB9 ALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLISYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLISYH
400 410 420 430 440 450
570 580
pF1KB9 MDNHLPIISAGSELCLQQPVERKL
::::::::::::::::::::::::
NP_003 MDNHLPIISAGSELCLQQPVERKL
460 470
>>NP_001123513 (OMIM: 600560) SHC-transforming protein 1 (473 aa)
initn: 2141 init1: 2141 opt: 3260 Z-score: 1937.7 bits: 368.2 E(85289): 3.4e-101
Smith-Waterman score: 3260; 99.8% identity (99.8% similar) in 474 aa overlap (111-584:1-473)
90 100 110 120 130 140
pF1KB9 KGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSF
::::::::::::::::::::::::::::::
NP_001 MNKLSGGGGRRTRVEGGQLGGEEWTRHGSF
10 20 30
150 160 170 180 190 200
pF1KB9 VNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVP
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB9 GAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSI
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB9 SFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPP
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB9 KLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAARPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAARPT
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB9 APNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGRELFDDPSYVNVQNLDKARQA
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
NP_001 APNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCP-GRELFDDPSYVNVQNLDKARQA
280 290 300 310 320
450 460 470 480 490 500
pF1KB9 VGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMAEQLRGEPWFHGKLSRREAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMAEQLRGEPWFHGKLSRREAE
330 340 350 360 370 380
510 520 530 540 550 560
pF1KB9 ALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLISYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLISYH
390 400 410 420 430 440
570 580
pF1KB9 MDNHLPIISAGSELCLQQPVERKL
::::::::::::::::::::::::
NP_001 MDNHLPIISAGSELCLQQPVERKL
450 460 470
>>XP_005245508 (OMIM: 600560) PREDICTED: SHC-transformin (488 aa)
initn: 2141 init1: 2141 opt: 2983 Z-score: 1774.7 bits: 338.1 E(85289): 4.1e-92
Smith-Waterman score: 2983; 99.8% identity (99.8% similar) in 433 aa overlap (111-543:1-432)
90 100 110 120 130 140
pF1KB9 KGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSF
::::::::::::::::::::::::::::::
XP_005 MNKLSGGGGRRTRVEGGQLGGEEWTRHGSF
10 20 30
150 160 170 180 190 200
pF1KB9 VNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVP
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB9 GAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSI
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB9 SFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPP
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB9 KLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAARPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAARPT
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB9 APNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGRELFDDPSYVNVQNLDKARQA
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_005 APNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCP-GRELFDDPSYVNVQNLDKARQA
280 290 300 310 320
450 460 470 480 490 500
pF1KB9 VGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMAEQLRGEPWFHGKLSRREAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMAEQLRGEPWFHGKLSRREAE
330 340 350 360 370 380
510 520 530 540 550 560
pF1KB9 ALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLISYH
:::::::::::::::::::::::::::::::::::::::::::
XP_005 ALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVSVAEVWVRGGKKEGTVP
390 400 410 420 430 440
570 580
pF1KB9 MDNHLPIISAGSELCLQQPVERKL
XP_005 YSVSLFLPSLLCRHSRWAAVYGPLLLFKVSGIFLQRLIP
450 460 470 480
>>NP_001189788 (OMIM: 600560) SHC-transforming protein 1 (428 aa)
initn: 1814 init1: 1814 opt: 2933 Z-score: 1745.9 bits: 332.6 E(85289): 1.6e-90
Smith-Waterman score: 2933; 99.8% identity (99.8% similar) in 429 aa overlap (156-584:1-428)
130 140 150 160 170 180
pF1KB9 GGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRT
::::::::::::::::::::::::::::::
NP_001 MGPGVSYLVRYMGCVEVLQSMRALDFNTRT
10 20 30
190 200 210 220 230 240
pF1KB9 QVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMA
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB9 ADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIG
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB9 QAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVD
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB9 MRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGRELFDD
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_001 MRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCP-GRELFDD
220 230 240 250 260
430 440 450 460 470 480
pF1KB9 PSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMAEQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMAEQLR
270 280 290 300 310 320
490 500 510 520 530 540
pF1KB9 GEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRT
330 340 350 360 370 380
550 560 570 580
pF1KB9 KDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL
:::::::::::::::::::::::::::::::::::::::
NP_001 KDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL
390 400 410 420
>>XP_011508200 (OMIM: 600560) PREDICTED: SHC-transformin (432 aa)
initn: 1738 init1: 1738 opt: 2580 Z-score: 1538.2 bits: 294.2 E(85289): 6.1e-79
Smith-Waterman score: 2580; 99.7% identity (99.7% similar) in 377 aa overlap (167-543:1-376)
140 150 160 170 180 190
pF1KB9 HGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVC
::::::::::::::::::::::::::::::
XP_011 MGCVEVLQSMRALDFNTRTQVTREAISLVC
10 20 30
200 210 220 230 240 250
pF1KB9 EAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHH
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB9 MQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYL
100 110 120 130 140 150
320 330 340 350 360 370
pF1KB9 RNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGA
160 170 180 190 200 210
380 390 400 410 420 430
pF1KB9 ARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGRELFDDPSYVNVQNLDK
::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_011 ARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCP-GRELFDDPSYVNVQNLDK
220 230 240 250 260
440 450 460 470 480 490
pF1KB9 ARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMAEQLRGEPWFHGKLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMAEQLRGEPWFHGKLSR
270 280 290 300 310 320
500 510 520 530 540 550
pF1KB9 REAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHL
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVSVAEVWVRGGKKE
330 340 350 360 370 380
560 570 580
pF1KB9 ISYHMDNHLPIISAGSELCLQQPVERKL
XP_011 GTVPYSVSLFLPSLLCRHSRWAAVYGPLLLFKVSGIFLQRLIP
390 400 410 420 430
>>XP_011508194 (OMIM: 600560) PREDICTED: SHC-transformin (593 aa)
initn: 4026 init1: 2235 opt: 2281 Z-score: 1360.8 bits: 261.8 E(85289): 4.7e-69
Smith-Waterman score: 4012; 98.5% identity (98.5% similar) in 593 aa overlap (1-584:1-593)
10 20 30 40 50 60
pF1KB9 MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 ISTIGQAFELRFKQYLRNPPKLVTPHD---------RMAGFDGSAWDEEEEEPPDHQYYN
::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_011 ISTIGQAFELRFKQYLRNPPKLVTPHDSHSFTVLSLRMAGFDGSAWDEEEEEPPDHQYYN
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB9 DFPGKEPPLGGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFPGKEPPLGGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB9 PPPPCPAGRELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPPCPAGRELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB9 PPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQP
490 500 510 520 530 540
540 550 560 570 580
pF1KB9 KHLLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHLLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL
550 560 570 580 590
584 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:06:14 2016 done: Sat Nov 5 16:06:16 2016
Total Scan time: 13.220 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]