Result of FASTA (omim) for
pFN21AB5419
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5419, 318 aa
1>>>pF1KB5419 318 - 318 aa - 318 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7963+/-0.000649; mu= 19.2565+/- 0.040
mean_var=129.2299+/-36.948, 0's: 0 Z-trim(105.4): 599 B-trim: 849 in 1/48
Lambda= 0.112822
statistics sampled from 12831 (13570) to 12831 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.455), E-opt: 0.2 (0.159), width: 16
Scan time: 6.770
The best scores are: opt bits E(85289)
NP_000668 (OMIM: 600445) adenosine receptor A3 iso ( 318) 2063 348.3 1.3e-95
NP_001289608 (OMIM: 600445) adenosine receptor A3 ( 173) 1145 198.4 8.6e-51
NP_000665 (OMIM: 102775) adenosine receptor A1 [Ho ( 326) 859 152.3 1.2e-36
NP_001041695 (OMIM: 102775) adenosine receptor A1 ( 326) 859 152.3 1.2e-36
NP_001289607 (OMIM: 600445) adenosine receptor A3 ( 123) 714 128.1 9.4e-30
XP_005244959 (OMIM: 102775) PREDICTED: adenosine r ( 258) 637 116.0 8.3e-26
XP_016855831 (OMIM: 102775) PREDICTED: adenosine r ( 258) 637 116.0 8.3e-26
XP_005244958 (OMIM: 102775) PREDICTED: adenosine r ( 258) 637 116.0 8.3e-26
NP_001265427 (OMIM: 102776) adenosine receptor A2a ( 412) 582 107.4 5.3e-23
NP_001265429 (OMIM: 102776) adenosine receptor A2a ( 412) 582 107.4 5.3e-23
NP_001265426 (OMIM: 102776) adenosine receptor A2a ( 412) 582 107.4 5.3e-23
NP_000666 (OMIM: 102776) adenosine receptor A2a [H ( 412) 582 107.4 5.3e-23
NP_001265428 (OMIM: 102776) adenosine receptor A2a ( 412) 582 107.4 5.3e-23
NP_000667 (OMIM: 600446) adenosine receptor A2b [H ( 332) 462 87.7 3.6e-17
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359) 404 78.3 2.6e-14
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362) 404 78.3 2.6e-14
NP_001124527 (OMIM: 142703) histamine H2 receptor ( 397) 404 78.4 2.7e-14
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422) 404 78.4 2.8e-14
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422) 404 78.4 2.8e-14
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422) 404 78.4 2.8e-14
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422) 404 78.4 2.8e-14
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422) 404 78.4 2.8e-14
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 369 72.8 1.6e-12
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 369 72.9 1.7e-12
XP_011521963 (OMIM: 600446) PREDICTED: adenosine r ( 116) 347 68.3 8.7e-12
XP_011521961 (OMIM: 600446) PREDICTED: adenosine r ( 229) 348 68.9 1.1e-11
XP_016879686 (OMIM: 600446) PREDICTED: adenosine r ( 231) 348 68.9 1.1e-11
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349) 348 69.2 1.4e-11
NP_055137 (OMIM: 606695) opsin-3 [Homo sapiens] ( 402) 345 68.8 2.1e-11
NP_000515 (OMIM: 109760,614674) 5-hydroxytryptamin ( 422) 341 68.2 3.4e-11
NP_003958 (OMIM: 607405) trace amine-associated re ( 337) 332 66.6 8.4e-11
XP_016872446 (OMIM: 606665) PREDICTED: melanopsin ( 405) 330 66.4 1.2e-10
NP_001025186 (OMIM: 606665) melanopsin isoform 2 [ ( 489) 330 66.5 1.3e-10
NP_006574 (OMIM: 605224) visual pigment-like recep ( 337) 328 65.9 1.3e-10
XP_016872444 (OMIM: 606665) PREDICTED: melanopsin ( 539) 330 66.5 1.4e-10
NP_001391 (OMIM: 601974) sphingosine 1-phosphate r ( 382) 322 65.0 2.8e-10
NP_001307659 (OMIM: 601974) sphingosine 1-phosphat ( 382) 322 65.0 2.8e-10
NP_005277 (OMIM: 600731) neuropeptides B/W recepto ( 333) 318 64.3 4.1e-10
NP_005950 (OMIM: 125853,600804) melatonin receptor ( 362) 318 64.3 4.3e-10
XP_011541141 (OMIM: 125853,600804) PREDICTED: mela ( 362) 318 64.3 4.3e-10
NP_000016 (OMIM: 109691,601665) beta-3 adrenergic ( 408) 316 64.1 5.7e-10
NP_005949 (OMIM: 600665) melatonin receptor type 1 ( 350) 315 63.8 5.9e-10
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 313 63.5 7.6e-10
NP_778237 (OMIM: 608923) trace amine-associated re ( 345) 310 63.0 1e-09
XP_011543044 (OMIM: 118510) PREDICTED: muscarinic ( 460) 311 63.3 1.1e-09
NP_000729 (OMIM: 118510) muscarinic acetylcholine ( 460) 311 63.3 1.1e-09
XP_005251990 (OMIM: 601909) PREDICTED: probable G- ( 349) 303 61.9 2.3e-09
NP_005285 (OMIM: 601909) probable G-protein couple ( 349) 303 61.9 2.3e-09
XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B ad ( 328) 302 61.7 2.5e-09
XP_006714884 (OMIM: 104220) PREDICTED: alpha-1B ad ( 331) 302 61.7 2.5e-09
>>NP_000668 (OMIM: 600445) adenosine receptor A3 isoform (318 aa)
initn: 2063 init1: 2063 opt: 2063 Z-score: 1837.8 bits: 348.3 E(85289): 1.3e-95
Smith-Waterman score: 2063; 100.0% identity (100.0% similar) in 318 aa overlap (1-318:1-318)
10 20 30 40 50 60
pF1KB5 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
250 260 270 280 290 300
310
pF1KB5 VVCHPSDSLDTSIEKNSE
::::::::::::::::::
NP_000 VVCHPSDSLDTSIEKNSE
310
>>NP_001289608 (OMIM: 600445) adenosine receptor A3 isof (173 aa)
initn: 1145 init1: 1145 opt: 1145 Z-score: 1032.9 bits: 198.4 E(85289): 8.6e-51
Smith-Waterman score: 1145; 100.0% identity (100.0% similar) in 173 aa overlap (146-318:1-173)
120 130 140 150 160 170
pF1KB5 VRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMD
::::::::::::::::::::::::::::::
NP_001 MFGWNMKLTSEYHRNVTFLSCQFVSVMRMD
10 20 30
180 190 200 210 220 230
pF1KB5 YMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLV
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB5 LFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLL
100 110 120 130 140 150
300 310
pF1KB5 ILKACVVCHPSDSLDTSIEKNSE
:::::::::::::::::::::::
NP_001 ILKACVVCHPSDSLDTSIEKNSE
160 170
>>NP_000665 (OMIM: 102775) adenosine receptor A1 [Homo s (326 aa)
initn: 954 init1: 533 opt: 859 Z-score: 778.6 bits: 152.3 E(85289): 1.2e-36
Smith-Waterman score: 1010; 48.8% identity (78.9% similar) in 322 aa overlap (1-313:1-319)
10 20 30 40 50 60
pF1KB5 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
:: . .:.. : :: .:..:.: .. :::::: .::.: .:. .:: ::::::.::.:
NP_000 MPPSISAFQAA---YIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVA
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
::.::.::::....: .:..::...: .::.:..::..:::::::::::::. .:::
NP_000 VGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKM
60 70 80 90 100 110
130 140 150 160 170
pF1KB5 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSE--YHRNVTF----LSCQFVSVMRM
:.: :: .:.. ::..::.:::::::::: . : . : .. ..:.: .:. :
NP_000 VVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISM
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 DYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSK-ETGAFYGREFKTAKSLF
.:::::.:..:.. ::..: :::..::.::..:. ..: :. . .::.:.: ::::
NP_000 EYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 LVLFLFALSWLPLSIINCIIYF--NGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKE
:.::::::::::: :.::: : . . :... :..:.:.:.:: :::::::..:.::.
NP_000 LILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
240 250 260 270 280 290
300 310
pF1KB5 TYLLILKACVVCHPSDSLDTSIEKNSE
:.: : . :.:. .: ..
NP_000 TFLKIWNDHFRCQPAPPIDEDLPEERPDD
300 310 320
>>NP_001041695 (OMIM: 102775) adenosine receptor A1 [Hom (326 aa)
initn: 954 init1: 533 opt: 859 Z-score: 778.6 bits: 152.3 E(85289): 1.2e-36
Smith-Waterman score: 1010; 48.8% identity (78.9% similar) in 322 aa overlap (1-313:1-319)
10 20 30 40 50 60
pF1KB5 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
:: . .:.. : :: .:..:.: .. :::::: .::.: .:. .:: ::::::.::.:
NP_001 MPPSISAFQAA---YIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVA
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
::.::.::::....: .:..::...: .::.:..::..:::::::::::::. .:::
NP_001 VGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKM
60 70 80 90 100 110
130 140 150 160 170
pF1KB5 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSE--YHRNVTF----LSCQFVSVMRM
:.: :: .:.. ::..::.:::::::::: . : . : .. ..:.: .:. :
NP_001 VVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISM
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 DYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSK-ETGAFYGREFKTAKSLF
.:::::.:..:.. ::..: :::..::.::..:. ..: :. . .::.:.: ::::
NP_001 EYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 LVLFLFALSWLPLSIINCIIYF--NGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKE
:.::::::::::: :.::: : . . :... :..:.:.:.:: :::::::..:.::.
NP_001 LILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
240 250 260 270 280 290
300 310
pF1KB5 TYLLILKACVVCHPSDSLDTSIEKNSE
:.: : . :.:. .: ..
NP_001 TFLKIWNDHFRCQPAPPIDEDLPEERPDD
300 310 320
>>NP_001289607 (OMIM: 600445) adenosine receptor A3 isof (123 aa)
initn: 714 init1: 714 opt: 714 Z-score: 655.2 bits: 128.1 E(85289): 9.4e-30
Smith-Waterman score: 714; 100.0% identity (100.0% similar) in 116 aa overlap (1-116:1-116)
10 20 30 40 50 60
pF1KB5 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVSSIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
NP_001 PTL
>>XP_005244959 (OMIM: 102775) PREDICTED: adenosine recep (258 aa)
initn: 589 init1: 190 opt: 637 Z-score: 584.3 bits: 116.0 E(85289): 8.3e-26
Smith-Waterman score: 637; 46.4% identity (75.6% similar) in 209 aa overlap (114-313:43-251)
90 100 110 120 130 140
pF1KB5 LFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGL
:. ::: :.: :: .:.. ::..::.:::
XP_005 GAPLRGPWRPGVPQRGLSRQLGGRSSHSALLSPRYKMVVTPRRAAVAIAGCWILSFVVGL
20 30 40 50 60 70
150 160 170 180 190
pF1KB5 TPMFGWNMKLTSE--YHRNVTF----LSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIY
::::::: . : . : .. ..:.: .:. :.:::::.:..:.. ::..: ::
XP_005 TPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIY
80 90 100 110 120 130
200 210 220 230 240 250
pF1KB5 LDIFYIIRNKLSLNLSNSK-ETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYF-
:..::.::..:. ..: :. . .::.:.: :::: :.::::::::::: :.::: :
XP_005 LEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFC
140 150 160 170 180 190
260 270 280 290 300 310
pF1KB5 -NGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIE
. . :... :..:.:.:.:: :::::::..:.::. :.: : . :.:. .: ..
XP_005 PSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLP
200 210 220 230 240 250
pF1KB5 KNSE
XP_005 EERPDD
>>XP_016855831 (OMIM: 102775) PREDICTED: adenosine recep (258 aa)
initn: 589 init1: 190 opt: 637 Z-score: 584.3 bits: 116.0 E(85289): 8.3e-26
Smith-Waterman score: 637; 46.4% identity (75.6% similar) in 209 aa overlap (114-313:43-251)
90 100 110 120 130 140
pF1KB5 LFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGL
:. ::: :.: :: .:.. ::..::.:::
XP_016 GAPLRGPWRPGVPQRGLSRQLGGRSSHSALLSPRYKMVVTPRRAAVAIAGCWILSFVVGL
20 30 40 50 60 70
150 160 170 180 190
pF1KB5 TPMFGWNMKLTSE--YHRNVTF----LSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIY
::::::: . : . : .. ..:.: .:. :.:::::.:..:.. ::..: ::
XP_016 TPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIY
80 90 100 110 120 130
200 210 220 230 240 250
pF1KB5 LDIFYIIRNKLSLNLSNSK-ETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYF-
:..::.::..:. ..: :. . .::.:.: :::: :.::::::::::: :.::: :
XP_016 LEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFC
140 150 160 170 180 190
260 270 280 290 300 310
pF1KB5 -NGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIE
. . :... :..:.:.:.:: :::::::..:.::. :.: : . :.:. .: ..
XP_016 PSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLP
200 210 220 230 240 250
pF1KB5 KNSE
XP_016 EERPDD
>>XP_005244958 (OMIM: 102775) PREDICTED: adenosine recep (258 aa)
initn: 589 init1: 190 opt: 637 Z-score: 584.3 bits: 116.0 E(85289): 8.3e-26
Smith-Waterman score: 637; 46.4% identity (75.6% similar) in 209 aa overlap (114-313:43-251)
90 100 110 120 130 140
pF1KB5 LFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGL
:. ::: :.: :: .:.. ::..::.:::
XP_005 GAPLRGPWRPGVPQRGLSRQLGGRSSHSALLSPRYKMVVTPRRAAVAIAGCWILSFVVGL
20 30 40 50 60 70
150 160 170 180 190
pF1KB5 TPMFGWNMKLTSE--YHRNVTF----LSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIY
::::::: . : . : .. ..:.: .:. :.:::::.:..:.. ::..: ::
XP_005 TPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIY
80 90 100 110 120 130
200 210 220 230 240 250
pF1KB5 LDIFYIIRNKLSLNLSNSK-ETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYF-
:..::.::..:. ..: :. . .::.:.: :::: :.::::::::::: :.::: :
XP_005 LEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFC
140 150 160 170 180 190
260 270 280 290 300 310
pF1KB5 -NGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIE
. . :... :..:.:.:.:: :::::::..:.::. :.: : . :.:. .: ..
XP_005 PSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLP
200 210 220 230 240 250
pF1KB5 KNSE
XP_005 EERPDD
>>NP_001265427 (OMIM: 102776) adenosine receptor A2a [Ho (412 aa)
initn: 770 init1: 474 opt: 582 Z-score: 534.0 bits: 107.4 E(85289): 5.3e-23
Smith-Waterman score: 811; 41.6% identity (75.4% similar) in 305 aa overlap (10-302:4-308)
10 20 30 40 50 60
pF1KB5 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
... .:::.:. :.. ::.::::: .: :: .::..: ::.:::: ::::
NP_001 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIA
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
::::..:.::..: :. ..:::..:..:..:..::.::::::.:::. ... .::.
NP_001 VGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNG
60 70 80 90 100 110
130 140 150 160 170
pF1KB5 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTF------LSCQFVSVMRM
..: : ...::..:: .:::::.::: . .: . ..: : .:. :
NP_001 LVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPM
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 DYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSN---SKETGAFYGREFKTAKS
.:::::.:.. ...::..: ..:: :: : .:. :. .... . .: ..:::
NP_001 NYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKS
180 190 200 210 220 230
240 250 260 270 280
pF1KB5 LFLVLFLFALSWLPLSIINCIIYFNGE---VPQLVLYMGILLSHANSMMNPIVYAYKIKK
: ... :::: :::: ::::. .: . .: ..:..:.:::.::..::..:::.:..
NP_001 LAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIRE
240 250 260 270 280 290
290 300 310
pF1KB5 FKETYLLILKACVVCHPSDSLDTSIEKNSE
:..:. :... :.
NP_001 FRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHP
300 310 320 330 340 350
>>NP_001265429 (OMIM: 102776) adenosine receptor A2a [Ho (412 aa)
initn: 770 init1: 474 opt: 582 Z-score: 534.0 bits: 107.4 E(85289): 5.3e-23
Smith-Waterman score: 811; 41.6% identity (75.4% similar) in 305 aa overlap (10-302:4-308)
10 20 30 40 50 60
pF1KB5 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
... .:::.:. :.. ::.::::: .: :: .::..: ::.:::: ::::
NP_001 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIA
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
::::..:.::..: :. ..:::..:..:..:..::.::::::.:::. ... .::.
NP_001 VGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNG
60 70 80 90 100 110
130 140 150 160 170
pF1KB5 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTF------LSCQFVSVMRM
..: : ...::..:: .:::::.::: . .: . ..: : .:. :
NP_001 LVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPM
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 DYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSN---SKETGAFYGREFKTAKS
.:::::.:.. ...::..: ..:: :: : .:. :. .... . .: ..:::
NP_001 NYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKS
180 190 200 210 220 230
240 250 260 270 280
pF1KB5 LFLVLFLFALSWLPLSIINCIIYFNGE---VPQLVLYMGILLSHANSMMNPIVYAYKIKK
: ... :::: :::: ::::. .: . .: ..:..:.:::.::..::..:::.:..
NP_001 LAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIRE
240 250 260 270 280 290
290 300 310
pF1KB5 FKETYLLILKACVVCHPSDSLDTSIEKNSE
:..:. :... :.
NP_001 FRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHP
300 310 320 330 340 350
318 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:44:50 2016 done: Sat Nov 5 12:44:51 2016
Total Scan time: 6.770 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]