Result of FASTA (omim) for
pFN21AB5284
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5284, 189 aa
1>>>pF1KB5284 189 - 189 aa - 189 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7680+/-0.000383; mu= -2.3573+/- 0.024
mean_var=211.5204+/-43.264, 0's: 0 Z-trim(119.5): 9 B-trim: 864 in 2/53
Lambda= 0.088186
statistics sampled from 33618 (33627) to 33618 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.747), E-opt: 0.2 (0.394), width: 16
Scan time: 6.520
The best scores are: opt bits E(85289)
NP_981946 (OMIM: 151442) stathmin isoform a [Homo ( 149) 623 90.9 1e-18
NP_981944 (OMIM: 151442) stathmin isoform a [Homo ( 149) 623 90.9 1e-18
NP_005554 (OMIM: 151442) stathmin isoform a [Homo ( 149) 623 90.9 1e-18
XP_005251199 (OMIM: 600621) PREDICTED: stathmin-2 ( 174) 601 88.2 8e-18
NP_008960 (OMIM: 600621) stathmin-2 isoform 2 [Hom ( 179) 601 88.2 8.1e-18
NP_001263239 (OMIM: 608362) stathmin-3 isoform 2 [ ( 169) 562 83.2 2.4e-16
NP_056978 (OMIM: 608362) stathmin-3 isoform 1 [Hom ( 180) 562 83.2 2.5e-16
NP_001138926 (OMIM: 151442) stathmin isoform b [Ho ( 174) 542 80.7 1.4e-15
NP_001186143 (OMIM: 600621) stathmin-2 isoform 1 [ ( 187) 529 79.1 4.8e-15
>>NP_981946 (OMIM: 151442) stathmin isoform a [Homo sapi (149 aa)
initn: 711 init1: 623 opt: 623 Z-score: 457.1 bits: 90.9 E(85289): 1e-18
Smith-Waterman score: 623; 72.1% identity (90.0% similar) in 140 aa overlap (48-187:4-143)
20 30 40 50 60 70
pF1KB5 LFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVP
::..: ::.: .:::.::.::.: : ..::
NP_981 MASSDIQVKELEKRASGQAFELILSPRSKESVP
10 20 30
80 90 100 110 120 130
pF1KB5 EFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNF
:: : :...: ::::::::::::::::: .:::.::.::::::::.::.::::::::::
NP_981 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF
40 50 60 70 80 90
140 150 160 170 180
pF1KB5 IKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR
:::.:::..:::.:::::::..:: ::::.::::: :::::::: :. :
NP_981 SKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD
100 110 120 130 140
>>NP_981944 (OMIM: 151442) stathmin isoform a [Homo sapi (149 aa)
initn: 711 init1: 623 opt: 623 Z-score: 457.1 bits: 90.9 E(85289): 1e-18
Smith-Waterman score: 623; 72.1% identity (90.0% similar) in 140 aa overlap (48-187:4-143)
20 30 40 50 60 70
pF1KB5 LFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVP
::..: ::.: .:::.::.::.: : ..::
NP_981 MASSDIQVKELEKRASGQAFELILSPRSKESVP
10 20 30
80 90 100 110 120 130
pF1KB5 EFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNF
:: : :...: ::::::::::::::::: .:::.::.::::::::.::.::::::::::
NP_981 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF
40 50 60 70 80 90
140 150 160 170 180
pF1KB5 IKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR
:::.:::..:::.:::::::..:: ::::.::::: :::::::: :. :
NP_981 SKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD
100 110 120 130 140
>>NP_005554 (OMIM: 151442) stathmin isoform a [Homo sapi (149 aa)
initn: 711 init1: 623 opt: 623 Z-score: 457.1 bits: 90.9 E(85289): 1e-18
Smith-Waterman score: 623; 72.1% identity (90.0% similar) in 140 aa overlap (48-187:4-143)
20 30 40 50 60 70
pF1KB5 LFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVP
::..: ::.: .:::.::.::.: : ..::
NP_005 MASSDIQVKELEKRASGQAFELILSPRSKESVP
10 20 30
80 90 100 110 120 130
pF1KB5 EFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNF
:: : :...: ::::::::::::::::: .:::.::.::::::::.::.::::::::::
NP_005 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF
40 50 60 70 80 90
140 150 160 170 180
pF1KB5 IKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR
:::.:::..:::.:::::::..:: ::::.::::: :::::::: :. :
NP_005 SKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD
100 110 120 130 140
>>XP_005251199 (OMIM: 600621) PREDICTED: stathmin-2 isof (174 aa)
initn: 755 init1: 590 opt: 601 Z-score: 441.0 bits: 88.2 E(85289): 8e-18
Smith-Waterman score: 696; 63.8% identity (81.1% similar) in 185 aa overlap (5-188:2-173)
10 20 30 40 50 60
pF1KB5 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTS
::::::::: ..::.:::: .: : . : :. :::: ..:: .:
XP_005 MAYKEKMKELSMLSLICSCFYPEPRNINIYTYD------------DMEVKQINKRAS
10 20 30 40
70 80 90 100 110
pF1KB5 GQSFEVILKPPS-FDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEK
::.::.:::::: .. .:. :: :...: ::::::::::::::::: :::..::.::::
XP_005 GQAFELILKPPSPISEAPRTLAS-PKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 REHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRK
:::::::.:::.:::::: :::.::: :::. ::::::.:::..::::::..:: :::.
XP_005 REHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRR
110 120 130 140 150 160
180
pF1KB5 NKELKEEASR
::::. : :
XP_005 NKELQVELSG
170
>>NP_008960 (OMIM: 600621) stathmin-2 isoform 2 [Homo sa (179 aa)
initn: 755 init1: 590 opt: 601 Z-score: 440.8 bits: 88.2 E(85289): 8.1e-18
Smith-Waterman score: 698; 63.3% identity (80.3% similar) in 188 aa overlap (2-188:4-178)
10 20 30 40 50
pF1KB5 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKC
: ::::::::: ..::.:::: .: : . : :. :::: ..::
NP_008 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYD------------DMEVKQINKR
10 20 30 40
60 70 80 90 100 110
pF1KB5 TSGQSFEVILKPPS-FDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLA
.:::.::.:::::: .. .:. :: :...: ::::::::::::::::: :::..::.::
NP_008 ASGQAFELILKPPSPISEAPRTLAS-PKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLA
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 EKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEV
:::::::::.:::.:::::: :::.::: :::. ::::::.:::..::::::..:: ::
NP_008 EKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEV
110 120 130 140 150 160
180
pF1KB5 RKNKELKEEASR
:.::::. : :
NP_008 RRNKELQVELSG
170
>>NP_001263239 (OMIM: 608362) stathmin-3 isoform 2 [Homo (169 aa)
initn: 661 init1: 438 opt: 562 Z-score: 414.4 bits: 83.2 E(85289): 2.4e-16
Smith-Waterman score: 624; 59.1% identity (78.5% similar) in 181 aa overlap (10-188:1-168)
10 20 30 40 50 60
pF1KB5 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTS
:::: ..::.:::: ..: .. :.: .:::: .:.: .:
NP_001 MKELSVLSLICSCFYTQPHPNTVYQY------------GDMEVKQLDKRAS
10 20 30
70 80 90 100 110
pF1KB5 GQSFEVILKPPSFDGVPE--FNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAE
::::::::: :: : :: . .: :...: ::::.::.::::::::: :::..::.:::
NP_001 GQSFEVILKSPS-DLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAE
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB5 KREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVR
.:::::::..::.:::::: ..:.::: ::: .:: :::::::. :::.::. :: :::
NP_001 RREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVR
100 110 120 130 140 150
180
pF1KB5 KNKELKEEASR
.::: .:: :
NP_001 RNKEQREEMSG
160
>>NP_056978 (OMIM: 608362) stathmin-3 isoform 1 [Homo sa (180 aa)
initn: 700 init1: 438 opt: 562 Z-score: 414.0 bits: 83.2 E(85289): 2.5e-16
Smith-Waterman score: 663; 59.8% identity (79.4% similar) in 189 aa overlap (2-188:4-179)
10 20 30 40 50
pF1KB5 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKC
:..::::::::: ..::.:::: ..: .. :.: .:::: .:.:
NP_056 MASTISAYKEKMKELSVLSLICSCFYTQPHPNTVYQY------------GDMEVKQLDKR
10 20 30 40
60 70 80 90 100 110
pF1KB5 TSGQSFEVILKPPSFDGVPE--FNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHL
.:::::::::: :: : :: . .: :...: ::::.::.::::::::: :::..::.:
NP_056 ASGQSFEVILKSPS-DLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQL
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 AEKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEE
::.:::::::..::.:::::: ..:.::: ::: .:: :::::::. :::.::. :: :
NP_056 AERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAE
110 120 130 140 150 160
180
pF1KB5 VRKNKELKEEASR
::.::: .:: :
NP_056 VRRNKEQREEMSG
170 180
>>NP_001138926 (OMIM: 151442) stathmin isoform b [Homo s (174 aa)
initn: 542 init1: 542 opt: 542 Z-score: 400.4 bits: 80.7 E(85289): 1.4e-15
Smith-Waterman score: 542; 71.5% identity (91.1% similar) in 123 aa overlap (48-170:4-126)
20 30 40 50 60 70
pF1KB5 LFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDGVP
::..: ::.: .:::.::.::.: : ..::
NP_001 MASSDIQVKELEKRASGQAFELILSPRSKESVP
10 20 30
80 90 100 110 120 130
pF1KB5 EFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNF
:: : :...: ::::::::::::::::: .:::.::.::::::::.::.::::::::::
NP_001 EFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNF
40 50 60 70 80 90
140 150 160 170 180
pF1KB5 IKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR
:::.:::..:::.:::::::..:: ::::.::
NP_001 SKMAEEKLTHKMEANKENREAQMAAKLERLREKMYFWTHGPGAHPAQISAEQSCLHSVPA
100 110 120 130 140 150
NP_001 LCPALGLQSALITWSDLSHHH
160 170
>>NP_001186143 (OMIM: 600621) stathmin-2 isoform 1 [Homo (187 aa)
initn: 625 init1: 518 opt: 529 Z-score: 391.1 bits: 79.1 E(85289): 4.8e-15
Smith-Waterman score: 626; 63.5% identity (80.0% similar) in 170 aa overlap (2-170:4-160)
10 20 30 40 50
pF1KB5 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKC
: ::::::::: ..::.:::: .: : . : :. :::: ..::
NP_001 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYD------------DMEVKQINKR
10 20 30 40
60 70 80 90 100 110
pF1KB5 TSGQSFEVILKPPS-FDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLA
.:::.::.:::::: .. .:. :: :...: ::::::::::::::::: :::..::.::
NP_001 ASGQAFELILKPPSPISEAPRTLAS-PKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLA
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 EKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEV
:::::::::.:::.:::::: :::.::: :::. ::::::.:::..::::::
NP_001 EKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKLVKFISS
110 120 130 140 150 160
180
pF1KB5 RKNKELKEEASR
NP_001 ELKESIESQFLELQREGEKQ
170 180
189 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:24:08 2016 done: Sat Nov 5 12:24:09 2016
Total Scan time: 6.520 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]