Result of FASTA (omim) for
pFN21AE0914
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0914, 257 aa
1>>>pF1KE0914 257 - 257 aa - 257 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4546+/-0.000265; mu= 5.7345+/- 0.017
mean_var=123.1957+/-24.967, 0's: 0 Z-trim(123.3): 7 B-trim: 555 in 1/58
Lambda= 0.115552
statistics sampled from 42881 (42888) to 42881 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.503), width: 16
Scan time: 7.970
The best scores are: opt bits E(85289)
NP_002458 (OMIM: 113970,190080) myc proto-oncogene ( 454) 1710 295.2 1.4e-79
XP_016859657 (OMIM: 164280,164840,189960) PREDICTE ( 464) 293 58.9 1.8e-08
NP_005369 (OMIM: 164280,164840,189960) N-myc proto ( 464) 293 58.9 1.8e-08
NP_001280157 (OMIM: 164280,164840,189960) N-myc pr ( 464) 293 58.9 1.8e-08
NP_005367 (OMIM: 164850) protein L-Myc isoform 2 [ ( 236) 187 41.1 0.0021
NP_001028254 (OMIM: 164850) protein L-Myc isoform ( 394) 187 41.2 0.0033
NP_001028253 (OMIM: 164850) protein L-Myc isoform ( 364) 177 39.6 0.0098
>>NP_002458 (OMIM: 113970,190080) myc proto-oncogene pro (454 aa)
initn: 1710 init1: 1710 opt: 1710 Z-score: 1549.7 bits: 295.2 E(85289): 1.4e-79
Smith-Waterman score: 1710; 100.0% identity (100.0% similar) in 252 aa overlap (1-252:16-267)
10 20 30 40
pF1KE0 MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAP
:::::::::::::::::::::::::::::::::::::::::::::
NP_002 MDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAP
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 SEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTEL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 LGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPA
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 RGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLS
190 200 210 220 230 240
230 240 250
pF1KE0 STESSPQGSPEPLVLHEETPPTTSSDSGGTRR
:::::::::::::::::::::::::::
NP_002 STESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAG
250 260 270 280 290 300
>>XP_016859657 (OMIM: 164280,164840,189960) PREDICTED: N (464 aa)
initn: 292 init1: 147 opt: 293 Z-score: 272.9 bits: 58.9 E(85289): 1.8e-08
Smith-Waterman score: 382; 39.0% identity (56.9% similar) in 246 aa overlap (10-235:15-232)
10 20 30 40 50
pF1KE0 MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFEL
.: ::..::.:: :: ::.. :: .: ::. :::::::::
XP_016 MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDD-FYFGGPDS--TPPG--EDIWKKFEL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LPTPPLSPSRRSGLCS---PSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVN
:::::::::: . : ::.: : . : .:. : : :.. . ::: :
XP_016 LPTPPLSPSRGFAEHSSEPPSWV--TEMLL--ENELWG---SPAEEDAFGLGGLGGLTPN
60 70 80 90 100
120 130 140 150 160
pF1KE0 QSFICDPDDETFIKNIIIQDCMWSGFSAAAKL---VSEKL--------ASYQAARKDSGS
: .:.:::::::::: :: ::::: :. : .:.
XP_016 ------P--------VILQDCMWSGFSAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGA
110 120 130 140 150
170 180 190 200 210
pF1KE0 PNPA-RGHSVCS----TSSLYLQDLSAAASECIDPSVVFPYPLNDSS-SPKSCASQDSSA
.:: :::. . ... .:. :.::.::.::::.:.: .: : .. :
XP_016 ASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPFPVNKREPAPVPAAPASAPA
160 170 180 190 200 210
220 230 240 250
pF1KE0 FSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSGGTRR
.:. : .. ..: :.:
XP_016 AGPAVAS--GAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSDDEDDEEED
220 230 240 250 260 270
>>NP_005369 (OMIM: 164280,164840,189960) N-myc proto-onc (464 aa)
initn: 292 init1: 147 opt: 293 Z-score: 272.9 bits: 58.9 E(85289): 1.8e-08
Smith-Waterman score: 382; 39.0% identity (56.9% similar) in 246 aa overlap (10-235:15-232)
10 20 30 40 50
pF1KE0 MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFEL
.: ::..::.:: :: ::.. :: .: ::. :::::::::
NP_005 MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDD-FYFGGPDS--TPPG--EDIWKKFEL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LPTPPLSPSRRSGLCS---PSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVN
:::::::::: . : ::.: : . : .:. : : :.. . ::: :
NP_005 LPTPPLSPSRGFAEHSSEPPSWV--TEMLL--ENELWG---SPAEEDAFGLGGLGGLTPN
60 70 80 90 100
120 130 140 150 160
pF1KE0 QSFICDPDDETFIKNIIIQDCMWSGFSAAAKL---VSEKL--------ASYQAARKDSGS
: .:.:::::::::: :: ::::: :. : .:.
NP_005 ------P--------VILQDCMWSGFSAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGA
110 120 130 140 150
170 180 190 200 210
pF1KE0 PNPA-RGHSVCS----TSSLYLQDLSAAASECIDPSVVFPYPLNDSS-SPKSCASQDSSA
.:: :::. . ... .:. :.::.::.::::.:.: .: : .. :
NP_005 ASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPFPVNKREPAPVPAAPASAPA
160 170 180 190 200 210
220 230 240 250
pF1KE0 FSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSGGTRR
.:. : .. ..: :.:
NP_005 AGPAVAS--GAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSDDEDDEEED
220 230 240 250 260 270
>>NP_001280157 (OMIM: 164280,164840,189960) N-myc proto- (464 aa)
initn: 292 init1: 147 opt: 293 Z-score: 272.9 bits: 58.9 E(85289): 1.8e-08
Smith-Waterman score: 382; 39.0% identity (56.9% similar) in 246 aa overlap (10-235:15-232)
10 20 30 40 50
pF1KE0 MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFEL
.: ::..::.:: :: ::.. :: .: ::. :::::::::
NP_001 MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDD-FYFGGPDS--TPPG--EDIWKKFEL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LPTPPLSPSRRSGLCS---PSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVN
:::::::::: . : ::.: : . : .:. : : :.. . ::: :
NP_001 LPTPPLSPSRGFAEHSSEPPSWV--TEMLL--ENELWG---SPAEEDAFGLGGLGGLTPN
60 70 80 90 100
120 130 140 150 160
pF1KE0 QSFICDPDDETFIKNIIIQDCMWSGFSAAAKL---VSEKL--------ASYQAARKDSGS
: .:.:::::::::: :: ::::: :. : .:.
NP_001 ------P--------VILQDCMWSGFSAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGA
110 120 130 140 150
170 180 190 200 210
pF1KE0 PNPA-RGHSVCS----TSSLYLQDLSAAASECIDPSVVFPYPLNDSS-SPKSCASQDSSA
.:: :::. . ... .:. :.::.::.::::.:.: .: : .. :
NP_001 ASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPFPVNKREPAPVPAAPASAPA
160 170 180 190 200 210
220 230 240 250
pF1KE0 FSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSGGTRR
.:. : .. ..: :.:
NP_001 AGPAVAS--GAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSDDEDDEEED
220 230 240 250 260 270
>>NP_005367 (OMIM: 164850) protein L-Myc isoform 2 [Homo (236 aa)
initn: 258 init1: 132 opt: 187 Z-score: 182.0 bits: 41.1 E(85289): 0.0021
Smith-Waterman score: 264; 36.8% identity (51.0% similar) in 239 aa overlap (2-235:18-208)
10 20 30 40
pF1KE0 MPLNVSFT-NRNYDLDYDSVQPYFY-CDEEENFYQQQQQSELQP
::.:. ... :.:::: : ::: : :.::..
NP_005 MCVCAGCRAAPSRRGAGPLQVAGGWSEGADMDYDSYQHYFYDYDCGEDFYRST-------
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 PAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMV
::::::::::::.:.:: :: :: .:. : : : . :. :.:. :
NP_005 -APSEDIWKKFELVPSPPTSPPW--GL-GPG--AGDPAPGIGPPEPWPGG-CTGDEAESR
60 70 80 90 100
110 120 130 140 150
pF1KE0 TELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKL---VSEKLASYQAARKDS
. : : :: .::::::::: .: ::..:: : :
NP_005 GHSKGWGRNYAS-------------IIRRDCMWSGFSARERLERAVSDRLAP-GAPR---
110 120 130 140
160 170 180 190 200 210
pF1KE0 GSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPS
:.: : . : : :: : .:. . : ::.. ::. : :.. :::
NP_005 GNPPKASAAPDC-TPSL----------EAGNPAPAAPCPLGE---PKTQAC--SGSESPS
150 160 170 180 190
220 230 240 250
pF1KE0 SDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSGGTRR
:: . : : .: :
NP_005 -DSGKDLPEPSKRGPPHGWPKLCPCLRSGIGSSQALGPSPPLFG
200 210 220 230
>>NP_001028254 (OMIM: 164850) protein L-Myc isoform 3 [H (394 aa)
initn: 258 init1: 132 opt: 187 Z-score: 178.5 bits: 41.2 E(85289): 0.0033
Smith-Waterman score: 255; 32.3% identity (53.4% similar) in 251 aa overlap (2-246:18-225)
10 20 30 40
pF1KE0 MPLNVSFT-NRNYDLDYDSVQPYFY-CDEEENFYQQQQQSELQP
::.:. ... :.:::: : ::: : :.::..
NP_001 MCVCAGCRAAPSRRGAGPLQVAGGWSEGADMDYDSYQHYFYDYDCGEDFYRST-------
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 PAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMV
::::::::::::.:.:: :: :: .:. : : : . :. :.:. :
NP_001 -APSEDIWKKFELVPSPPTSPPW--GL-GPG--AGDPAPGIGPPEPWPGG-CTGDEAESR
60 70 80 90 100
110 120 130 140 150
pF1KE0 TELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKL---VSEKLASYQAARKDS
. : : :: .::::::::: .: ::..:: : :
NP_001 GHSKGWGRNYAS-------------IIRRDCMWSGFSARERLERAVSDRLAP-GAPR---
110 120 130 140
160 170 180 190 200 210
pF1KE0 GSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPS
:.: : . :. : : :. .:. . : ::.. .. ..:....: . : .
NP_001 GNPPKASAAPDCTPS------LEAG-----NPAPAAPCPLGEPKT-QACSGSESPSDSEN
150 160 170 180 190
220 230 240 250
pF1KE0 SDSLLSSTESSPQ-GSPEPLVLHEETPPTTSSDSGGTRR
. . ..:. . : .:... .. :
NP_001 EEIDVVTVEKRQSLGIRKPVTITVRADPLDPCMKHFHISIHQQQHNYAARFPPESCSQEE
200 210 220 230 240 250
>>NP_001028253 (OMIM: 164850) protein L-Myc isoform 1 [H (364 aa)
initn: 250 init1: 132 opt: 177 Z-score: 170.1 bits: 39.6 E(85289): 0.0098
Smith-Waterman score: 245; 32.8% identity (52.1% similar) in 238 aa overlap (14-246:1-195)
10 20 30 40 50
pF1KE0 MPLNVSFTNRNYDLDYDSVQPYFY-CDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTP
.:::: : ::: : :.::.. ::::::::::::.:.:
NP_001 MDYDSYQHYFYDYDCGEDFYRS--------TAPSEDIWKKFELVPSP
10 20 30
60 70 80 90 100 110
pF1KE0 PLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDP
: :: :: .:. : : : . :. :.:. : . : :
NP_001 PTSPPW--GL-GPG--AGDPAPGIGPPEPWPGG-CTGDEAESRGHSKGWGRNYAS-----
40 50 60 70 80
120 130 140 150 160 170
pF1KE0 DDETFIKNIIIQDCMWSGFSAAAKL---VSEKLASYQAARKDSGSPNPARGHSVCSTSSL
:: .::::::::: .: ::..:: : : :.: : . : : ::
NP_001 --------IIRRDCMWSGFSARERLERAVSDRLAP-GAPR---GNPPKASAAPDC-TPSL
90 100 110 120 130
180 190 200 210 220 230
pF1KE0 YLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQ-GSP
: .:. . : ::.. .. ..:....: . : . . . ..:. . :
NP_001 ----------EAGNPAPAAPCPLGEPKT-QACSGSESPSDSENEEIDVVTVEKRQSLGIR
140 150 160 170 180
240 250
pF1KE0 EPLVLHEETPPTTSSDSGGTRR
.:... .. :
NP_001 KPVTITVRADPLDPCMKHFHISIHQQQHNYAARFPPESCSQEEASERGPQEEVLERDAAG
190 200 210 220 230 240
257 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:07:47 2016 done: Sat Nov 5 12:07:48 2016
Total Scan time: 7.970 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]