Result of FASTA (omim) for
pFN21AB6677
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6677, 427 aa
1>>>pF1KB6677 427 - 427 aa - 427 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7986+/-0.00051; mu= 20.3733+/- 0.032
mean_var=107.4746+/-25.713, 0's: 0 Z-trim(109.5): 539 B-trim: 1986 in 2/53
Lambda= 0.123715
statistics sampled from 16979 (17665) to 16979 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.535), E-opt: 0.2 (0.207), width: 16
Scan time: 7.930
The best scores are: opt bits E(85289)
NP_001948 (OMIM: 131243,157300,616367) endothelin- ( 427) 2918 532.6 7.5e-151
NP_001116131 (OMIM: 131244,277580,600155,600501) e ( 442) 1611 299.3 1.3e-80
NP_000106 (OMIM: 131244,277580,600155,600501) endo ( 442) 1611 299.3 1.3e-80
NP_001188326 (OMIM: 131244,277580,600155,600501) e ( 532) 1611 299.4 1.4e-80
NP_003982 (OMIM: 131244,277580,600155,600501) endo ( 436) 1529 284.7 3.2e-76
NP_001243212 (OMIM: 131243,157300,616367) endothel ( 202) 1427 266.0 6.2e-71
NP_001159527 (OMIM: 131243,157300,616367) endothel ( 318) 1261 236.7 6.7e-62
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384) 606 119.9 1.2e-26
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 584 115.9 1.8e-25
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 539 107.9 4.7e-23
NP_005293 (OMIM: 602583) prosaposin receptor GPR37 ( 613) 491 99.6 2.3e-20
NP_940799 (OMIM: 601898) growth hormone secretagog ( 366) 403 83.6 9.1e-16
NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380) 403 83.6 9.3e-16
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 368 77.4 7.6e-14
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415) 354 74.9 4.2e-13
XP_011534148 (OMIM: 162341) PREDICTED: neuromedin- ( 283) 352 74.3 4.3e-13
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 347 73.6 9.7e-13
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 347 73.6 9.7e-13
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 347 73.6 9.8e-13
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 347 73.7 9.8e-13
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 347 73.7 9.9e-13
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 347 73.7 9.9e-13
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 347 73.7 1e-12
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 347 73.7 1e-12
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 347 73.7 1e-12
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 347 73.7 1e-12
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 347 73.8 1.1e-12
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 347 73.8 1.1e-12
XP_016866390 (OMIM: 162341) PREDICTED: neuromedin- ( 301) 339 72.1 2.2e-12
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375) 326 69.9 1.3e-11
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375) 326 69.9 1.3e-11
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 326 69.9 1.3e-11
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 326 69.9 1.3e-11
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 326 69.9 1.3e-11
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 326 69.9 1.3e-11
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 325 69.8 1.5e-11
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 325 69.8 1.5e-11
XP_016866391 (OMIM: 162341) PREDICTED: neuromedin- ( 242) 322 68.9 1.6e-11
NP_001311237 (OMIM: 162341) neuromedin-B receptor ( 242) 322 68.9 1.6e-11
NP_001311236 (OMIM: 162341) neuromedin-B receptor ( 242) 322 68.9 1.6e-11
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 325 69.9 1.7e-11
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 323 69.3 1.9e-11
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 323 69.4 1.9e-11
XP_011535972 (OMIM: 605108) PREDICTED: neuromedin- ( 321) 310 66.9 8.4e-11
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 308 66.7 1.3e-10
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 303 65.8 2.4e-10
NP_001272456 (OMIM: 600018) mu-type opioid recepto ( 292) 297 64.5 4e-10
NP_001138752 (OMIM: 600018) mu-type opioid recepto ( 300) 297 64.6 4e-10
NP_001272455 (OMIM: 600018) mu-type opioid recepto ( 300) 297 64.6 4e-10
XP_016866395 (OMIM: 600018) PREDICTED: mu-type opi ( 300) 297 64.6 4e-10
>>NP_001948 (OMIM: 131243,157300,616367) endothelin-1 re (427 aa)
initn: 2918 init1: 2918 opt: 2918 Z-score: 2829.3 bits: 532.6 E(85289): 7.5e-151
Smith-Waterman score: 2918; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KB6 METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 SNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 VDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 NSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRS
370 380 390 400 410 420
pF1KB6 SHKDSMN
:::::::
NP_001 SHKDSMN
>>NP_001116131 (OMIM: 131244,277580,600155,600501) endot (442 aa)
initn: 988 init1: 579 opt: 1611 Z-score: 1568.4 bits: 299.3 E(85289): 1.3e-80
Smith-Waterman score: 1611; 63.8% identity (85.0% similar) in 359 aa overlap (69-425:90-440)
40 50 60 70 80 90
pF1KB6 TFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGN
: .: .:::::::.:: .:..:..::
NP_001 ASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB6 ATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLC
.:::::::.::::::::: ::::::::::...:::.::::.:::: ::: :. .:
NP_001 STLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF-----GAEMC
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 KLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAI
:: ::.::.:::::::.:::::.:::::::::::..:::.: ::.::: ::..: .::.
NP_001 KLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAV
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB6 PEAIGFVMVPFEYRGEQHKTCMLNATSK--FMEFYQDVKDWWLFGFYFCMPLVCTAIFYT
:::::: .. ..:.: . :.:. ..: ::.::. .::::::.::::.::. ::.:::
NP_001 PEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYT
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 LMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEM
::::::: ...: ..:::..::::::::::::::::..:::::.::::::::: :.::.
NP_001 LMTCEMLRKKSG-MQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQN
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB6 DKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMT
: ::::::::::..::::::.:..::::::::::.:::.:::::.::::: : ::
NP_001 DPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWC-QSFEEKQ
360 370 380 390 400 410
400 410 420
pF1KB6 SVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
:. . . ...: .:.. : :::.: :
NP_001 SLEEKQSCLKFKANDHGYDNF-RSSNKYSSS
420 430 440
>>NP_000106 (OMIM: 131244,277580,600155,600501) endothel (442 aa)
initn: 988 init1: 579 opt: 1611 Z-score: 1568.4 bits: 299.3 E(85289): 1.3e-80
Smith-Waterman score: 1611; 63.8% identity (85.0% similar) in 359 aa overlap (69-425:90-440)
40 50 60 70 80 90
pF1KB6 TFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGN
: .: .:::::::.:: .:..:..::
NP_000 ASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB6 ATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLC
.:::::::.::::::::: ::::::::::...:::.::::.:::: ::: :. .:
NP_000 STLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF-----GAEMC
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 KLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAI
:: ::.::.:::::::.:::::.:::::::::::..:::.: ::.::: ::..: .::.
NP_000 KLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAV
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB6 PEAIGFVMVPFEYRGEQHKTCMLNATSK--FMEFYQDVKDWWLFGFYFCMPLVCTAIFYT
:::::: .. ..:.: . :.:. ..: ::.::. .::::::.::::.::. ::.:::
NP_000 PEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYT
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 LMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEM
::::::: ...: ..:::..::::::::::::::::..:::::.::::::::: :.::.
NP_000 LMTCEMLRKKSG-MQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQN
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB6 DKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMT
: ::::::::::..::::::.:..::::::::::.:::.:::::.::::: : ::
NP_000 DPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWC-QSFEEKQ
360 370 380 390 400 410
400 410 420
pF1KB6 SVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
:. . . ...: .:.. : :::.: :
NP_000 SLEEKQSCLKFKANDHGYDNF-RSSNKYSSS
420 430 440
>>NP_001188326 (OMIM: 131244,277580,600155,600501) endot (532 aa)
initn: 988 init1: 579 opt: 1611 Z-score: 1567.5 bits: 299.4 E(85289): 1.4e-80
Smith-Waterman score: 1611; 63.8% identity (85.0% similar) in 359 aa overlap (69-425:180-530)
40 50 60 70 80 90
pF1KB6 TFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGN
: .: .:::::::.:: .:..:..::
NP_001 ASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN
150 160 170 180 190 200
100 110 120 130 140 150
pF1KB6 ATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLC
.:::::::.::::::::: ::::::::::...:::.::::.:::: ::: :. .:
NP_001 STLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF-----GAEMC
210 220 230 240 250 260
160 170 180 190 200 210
pF1KB6 KLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAI
:: ::.::.:::::::.:::::.:::::::::::..:::.: ::.::: ::..: .::.
NP_001 KLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAV
270 280 290 300 310 320
220 230 240 250 260 270
pF1KB6 PEAIGFVMVPFEYRGEQHKTCMLNATSK--FMEFYQDVKDWWLFGFYFCMPLVCTAIFYT
:::::: .. ..:.: . :.:. ..: ::.::. .::::::.::::.::. ::.:::
NP_001 PEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYT
330 340 350 360 370 380
280 290 300 310 320 330
pF1KB6 LMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEM
::::::: ...: ..:::..::::::::::::::::..:::::.::::::::: :.::.
NP_001 LMTCEMLRKKSG-MQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQN
390 400 410 420 430 440
340 350 360 370 380 390
pF1KB6 DKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMT
: ::::::::::..::::::.:..::::::::::.:::.:::::.::::: : ::
NP_001 DPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWC-QSFEEKQ
450 460 470 480 490 500
400 410 420
pF1KB6 SVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
:. . . ...: .:.. : :::.: :
NP_001 SLEEKQSCLKFKANDHGYDNF-RSSNKYSSS
510 520 530
>>NP_003982 (OMIM: 131244,277580,600155,600501) endothel (436 aa)
initn: 940 init1: 531 opt: 1529 Z-score: 1489.4 bits: 284.7 E(85289): 3.2e-76
Smith-Waterman score: 1529; 61.8% identity (83.3% similar) in 353 aa overlap (69-415:90-436)
40 50 60 70 80 90
pF1KB6 TFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGN
: .: .:::::::.:: .:..:..::
NP_003 ASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB6 ATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLC
.:::::::.::::::::: ::::::::::...:::.::::.:::: ::: :. .:
NP_003 STLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF-----GAEMC
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 KLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAI
:: ::.::.:::::::.:::::.:::::::::::..:::.: ::.::: ::..: .::.
NP_003 KLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAV
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB6 PEAIGFVMVPFEYRGEQHKTCMLNATSK--FMEFYQDVKDWWLFGFYFCMPLVCTAIFYT
:::::: .. ..:.: . :.:. ..: ::.::. .::::::.::::.::. ::.:::
NP_003 PEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYT
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 LMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEM
::::::: ...: ..:::..::::::::::::::::..:::::.::::::::: :.::.
NP_003 LMTCEMLRKKSG-MQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQN
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB6 DKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMT
: ::::::::::..::::::.:..::::::::::.:::.:::::.. . .
NP_003 DPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKAGPHVGNKLVMLFSV
360 370 380 390 400 410
400 410 420
pF1KB6 SVPMNGTSIQ----WKNHDQNNHNTDRSSHKDSMN
.. .:: : : .. .::.
NP_003 NIECDGTVNQNPTMWPERKSNNN
420 430
>>NP_001243212 (OMIM: 131243,157300,616367) endothelin-1 (202 aa)
initn: 1427 init1: 1427 opt: 1427 Z-score: 1394.5 bits: 266.0 E(85289): 6.2e-71
Smith-Waterman score: 1427; 100.0% identity (100.0% similar) in 202 aa overlap (226-427:1-202)
200 210 220 230 240 250
pF1KB6 IGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVK
::::::::::::::::::::::::::::::
NP_001 MVPFEYRGEQHKTCMLNATSKFMEFYQDVK
10 20 30
260 270 280 290 300 310
pF1KB6 DWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIF
40 50 60 70 80 90
320 330 340 350 360 370
pF1KB6 ALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKK
100 110 120 130 140 150
380 390 400 410 420
pF1KB6 FKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
160 170 180 190 200
>>NP_001159527 (OMIM: 131243,157300,616367) endothelin-1 (318 aa)
initn: 1261 init1: 1261 opt: 1261 Z-score: 1232.3 bits: 236.7 E(85289): 6.7e-62
Smith-Waterman score: 1956; 74.5% identity (74.5% similar) in 427 aa overlap (1-427:1-318)
10 20 30 40 50 60
pF1KB6 METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 SNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALS
::::::::::::::::::::
NP_001 SLALGDLIYVVIDLPINVFK----------------------------------------
130 140
190 200 210 220 230 240
pF1KB6 VDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCM
NP_001 ------------------------------------------------------------
250 260 270 280 290 300
pF1KB6 LNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---------FYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ
150 160 170 180 190
310 320 330 340 350 360
pF1KB6 RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATM
200 210 220 230 240 250
370 380 390 400 410 420
pF1KB6 NSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRS
260 270 280 290 300 310
pF1KB6 SHKDSMN
:::::::
NP_001 SHKDSMN
>>NP_005305 (OMIM: 305670) gastrin-releasing peptide rec (384 aa)
initn: 422 init1: 237 opt: 606 Z-score: 599.6 bits: 119.9 E(85289): 1.2e-26
Smith-Waterman score: 606; 33.5% identity (65.2% similar) in 313 aa overlap (81-387:41-340)
60 70 80 90 100 110
pF1KB6 THQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKC
:. .. .:...:..:: ::..:. :
NP_005 LEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNITLIKIFCTVKS
20 30 40 50 60 70
120 130 140 150 160 170
pF1KB6 MRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVG
::: :: .:.:::::::. .. :... . :: :: :: . :::.::.: .:::
NP_005 MRNVPNLFISSLALGDLLLLITCAPVDASRYLADRW-----LFGRIGCKLIPFIQLTSVG
80 90 100 110 120
180 190 200 210 220
pF1KB6 ITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPF-
..:..: :::.:::.:.. .:. . .. . :::.:..::::::. . ::
NP_005 VSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFH
130 140 150 160 170 180
230 240 250 260 270 280
pF1KB6 -EYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNG
: .. .: :. :.. ... : .. .:: ...: ... ... .
NP_005 EESTNQTFISCAPYPHSN--ELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLI-QSAY
190 200 210 220 230 240
290 300 310 320 330 340
pF1KB6 SLRIALSEHLKQ----RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELL
.: . . :.:. :...::::. .: .::.::.: :. . .. :.:.: . .:
NP_005 NLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTS---ML
250 260 270 280 290
350 360 370 380 390 400
pF1KB6 SFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTS
:. . . :: :::.::.:::..::.:.. :.. : ::
NP_005 HFVTSI--CARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTTC
300 310 320 330 340 350
410 420
pF1KB6 IQWKNHDQNNHNTDRSSHKDSMN
NP_005 MTSLKSTNPSVATFSLINGNICHERYV
360 370 380
>>NP_002502 (OMIM: 162341) neuromedin-B receptor isoform (390 aa)
initn: 479 init1: 235 opt: 584 Z-score: 578.3 bits: 115.9 E(85289): 1.8e-25
Smith-Waterman score: 584; 30.8% identity (61.0% similar) in 377 aa overlap (49-416:11-371)
20 30 40 50 60 70
pF1KB6 ISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSA
::: . .: .: ... : . :.
NP_002 MPSKSLSNLSVTTGANESGSVP-EGWERDFLPASDGTTTE
10 20 30
80 90 100 110 120 130
pF1KB6 FKYINTVISCTIFI--VGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPI
. .. : ..: ::..:: :..:. :. ::. :: .:..:: :::. .. .:.
NP_002 LVIRCVIPSLYLLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPV
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 NVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGI
. :.:. ::. :: :::.: .: .:::..:..: :::.:::::... .:
NP_002 D-----ASRYFFDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTS
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB6 GIPLVTAIEIVSIWILSFILAIPEAI-GFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVK
: : : .. ..::..: .::.:::. . : . . .:. . :.. ..
NP_002 GALLRTCVKAMGIWVVSVLLAVPEAVFSEVARISSLDNSSFTACIPYPQTD--ELHPKIH
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB6 DWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ----RREVAKTVFCL
. .: :: .::. .:.: .. . : . .: .:: :. :...:: :. .
NP_002 SVLIFLVYFLIPLAIISIYYYHIA-KTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVF
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB6 VVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYF
: : .:::: :. . .. :::.: . ... : .. :. :::.::.:::.
NP_002 VGCFIFCWFPNHILYMYRSFNYNEIDPSLGHMIVTL-----VARVLSFGNSCVNPFALYL
280 290 300 310 320
380 390 400 410 420
pF1KB6 VSKKFKNCFQSCLCCC--CYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
.:..:. :.: ::: :: .. :: ....... . .: .:
NP_002 LSESFRRHFNSQLCCGRKSYQERG--TSYLLSSSAVRMTSLKSNAKNMVTNSVLLNGHSM
330 340 350 360 370 380
NP_002 KQEMAL
390
>>NP_001718 (OMIM: 300107) bombesin receptor subtype-3 [ (399 aa)
initn: 422 init1: 206 opt: 539 Z-score: 534.8 bits: 107.9 E(85289): 4.7e-23
Smith-Waterman score: 539; 31.6% identity (65.2% similar) in 316 aa overlap (88-387:48-348)
60 70 80 90 100 110
pF1KB6 VLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFI-------VGMVGNATLLRIIYQNKC
:.:.: ::..::: :.......:
NP_001 NDTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKS
20 30 40 50 60 70
120 130 140 150 160 170
pF1KB6 MRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVG
:.. :: .:.:::.:::. .. .:... . :: : :: . ::.. :.. .:::
NP_001 MQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWL-----FGRIGCKVLSFIRLTSVG
80 90 100 110 120 130
180 190 200 210 220 230
pF1KB6 ITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFE
..:..: ::.:::.::.. . : . : : .. .::.:.:.:.:::: . :.
NP_001 VSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFALPEAIFSNVYTFR
140 150 160 170 180 190
240 250 260 270 280
pF1KB6 --YRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNG
.. ..: .:: .. :.... : .. .:: ...:.:.. . . .
NP_001 DPNKNMTFESCTSYPVSK--KLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYK---S
200 210 220 230 240
290 300 310 320 330 340
pF1KB6 SLRIALSEH------LKQRREVAKTVFCLVVIFALCWFPLHLSRILKK-TVYNEMDKNRC
.: : :. ...:...:.::. ::..:::::.: :: . .. : . .: .
NP_001 TLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSA-
250 260 270 280 290 300
350 360 370 380 390 400
pF1KB6 ELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMN
. :.. . .. :: :::.::.:::..::.:.. :.. : ::
NP_001 --MHFIFTI--FSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADTSL
310 320 330 340 350 360
410 420
pF1KB6 GTSIQWKNHDQNNHNTDRSSHKDSMN
NP_001 TTLAVMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF
370 380 390
427 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:43:22 2016 done: Sat Nov 5 11:43:24 2016
Total Scan time: 7.930 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]