Result of FASTA (omim) for
pFN21AB5940
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5940, 540 aa
1>>>pF1KB5940 540 - 540 aa - 540 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6439+/-0.000399; mu= 17.4444+/- 0.025
mean_var=95.2263+/-20.474, 0's: 0 Z-trim(113.0): 296 B-trim: 774 in 1/52
Lambda= 0.131430
statistics sampled from 21767 (22114) to 21767 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.259), width: 16
Scan time: 9.190
The best scores are: opt bits E(85289)
NP_004481 (OMIM: 601524) growth factor receptor-bo ( 540) 3671 707.0 3.8e-203
NP_001290351 (OMIM: 601524) growth factor receptor ( 453) 2940 568.3 1.8e-161
XP_016859388 (OMIM: 601524) PREDICTED: growth fact ( 340) 2312 449.1 1e-125
XP_011509324 (OMIM: 601524) PREDICTED: growth fact ( 312) 2103 409.4 8e-114
XP_016867556 (OMIM: 601523) PREDICTED: growth fact ( 536) 1952 381.0 5e-105
XP_016867557 (OMIM: 601523) PREDICTED: growth fact ( 536) 1952 381.0 5e-105
NP_001001550 (OMIM: 601523) growth factor receptor ( 536) 1952 381.0 5e-105
XP_016867554 (OMIM: 601523) PREDICTED: growth fact ( 536) 1952 381.0 5e-105
XP_016867552 (OMIM: 601523) PREDICTED: growth fact ( 536) 1952 381.0 5e-105
XP_016867553 (OMIM: 601523) PREDICTED: growth fact ( 536) 1952 381.0 5e-105
NP_001001555 (OMIM: 601523) growth factor receptor ( 536) 1952 381.0 5e-105
XP_016867534 (OMIM: 601523) PREDICTED: growth fact ( 536) 1952 381.0 5e-105
XP_011513618 (OMIM: 601523) PREDICTED: growth fact ( 536) 1952 381.0 5e-105
XP_016867555 (OMIM: 601523) PREDICTED: growth fact ( 536) 1952 381.0 5e-105
XP_011513614 (OMIM: 601523) PREDICTED: growth fact ( 588) 1952 381.1 5.3e-105
NP_005302 (OMIM: 601523) growth factor receptor-bo ( 594) 1952 381.1 5.3e-105
XP_011513606 (OMIM: 601523) PREDICTED: growth fact ( 594) 1952 381.1 5.3e-105
XP_016867535 (OMIM: 601523) PREDICTED: growth fact ( 594) 1952 381.1 5.3e-105
XP_016867533 (OMIM: 601523) PREDICTED: growth fact ( 632) 1952 381.1 5.6e-105
XP_016867520 (OMIM: 601523) PREDICTED: growth fact ( 665) 1952 381.1 5.8e-105
XP_011513625 (OMIM: 601523) PREDICTED: growth fact ( 533) 1838 359.4 1.6e-98
XP_016867543 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867546 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867539 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867547 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867544 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867541 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867550 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867542 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867538 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867540 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867536 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867537 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867548 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867551 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867545 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867549 (OMIM: 601523) PREDICTED: growth fact ( 581) 1838 359.4 1.7e-98
XP_016867525 (OMIM: 601523) PREDICTED: growth fact ( 633) 1838 359.5 1.8e-98
XP_016867527 (OMIM: 601523) PREDICTED: growth fact ( 633) 1838 359.5 1.8e-98
XP_016867526 (OMIM: 601523) PREDICTED: growth fact ( 633) 1838 359.5 1.8e-98
XP_016867531 (OMIM: 601523) PREDICTED: growth fact ( 633) 1838 359.5 1.8e-98
XP_016867530 (OMIM: 601523) PREDICTED: growth fact ( 633) 1838 359.5 1.8e-98
XP_016867529 (OMIM: 601523) PREDICTED: growth fact ( 633) 1838 359.5 1.8e-98
XP_016867528 (OMIM: 601523) PREDICTED: growth fact ( 633) 1838 359.5 1.8e-98
XP_016867532 (OMIM: 601523) PREDICTED: growth fact ( 633) 1838 359.5 1.8e-98
XP_016867524 (OMIM: 601523) PREDICTED: growth fact ( 633) 1838 359.5 1.8e-98
XP_016867523 (OMIM: 601523) PREDICTED: growth fact ( 639) 1838 359.5 1.8e-98
XP_016867522 (OMIM: 601523) PREDICTED: growth fact ( 639) 1838 359.5 1.8e-98
XP_016867521 (OMIM: 601523) PREDICTED: growth fact ( 639) 1838 359.5 1.8e-98
XP_016867519 (OMIM: 601523) PREDICTED: growth fact ( 688) 1838 359.5 1.9e-98
>>NP_004481 (OMIM: 601524) growth factor receptor-bound (540 aa)
initn: 3671 init1: 3671 opt: 3671 Z-score: 3768.1 bits: 707.0 E(85289): 3.8e-203
Smith-Waterman score: 3671; 99.8% identity (100.0% similar) in 540 aa overlap (1-540:1-540)
10 20 30 40 50 60
pF1KB5 MTTSLQDGQSAASRAAARDSPLAAQVCGAAQGRGDAHDLAPAPWLHARALLPLPDGTRGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MTTSLQDGQSAASRAAARDSPLAAQVCGAAQGRGDAHDLAPAPWLHARALLPLPDGTRGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AADRRKKKDLDVPEMPSIPNPFPELCCSPITSVLSADLFPKANSRKKQVIKVYSEDETSR
:::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
NP_004 AADRRKKKDLDVPEMPSIPNPFPELCCSPFTSVLSADLFPKANSRKKQVIKVYSEDETSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 ALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PTNYGFCFKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGRSGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PTNYGFCFKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGRSGC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 SSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTHGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTHGSP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 TASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 HGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL
490 500 510 520 530 540
>>NP_001290351 (OMIM: 601524) growth factor receptor-bou (453 aa)
initn: 2940 init1: 2940 opt: 2940 Z-score: 3020.1 bits: 568.3 E(85289): 1.8e-161
Smith-Waterman score: 2940; 99.5% identity (100.0% similar) in 435 aa overlap (106-540:19-453)
80 90 100 110 120 130
pF1KB5 PSIPNPFPELCCSPITSVLSADLFPKANSRKKQVIKVYSEDETSRALDVPSDITARDVCQ
.:.:::::::::::::::::::::::::::
NP_001 MSLSARRVTLPAITPIILQKRVIKVYSEDETSRALDVPSDITARDVCQ
10 20 30 40
140 150 160 170 180 190
pF1KB5 LLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKNYAKYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIEEENKLYFRKNYAKYE
50 60 70 80 90 100
200 210 220 230 240 250
pF1KB5 FFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGFLHAKEQGKKSWKKIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGFLHAKEQGKKSWKKIY
110 120 130 140 150 160
260 270 280 290 300 310
pF1KB5 FFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFKPNKAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGAPTNYGFCFKPNKAGG
170 180 190 200 210 220
320 330 340 350 360 370
pF1KB5 PRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGRSGCSSQSISPMRSISENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGRSGCSSQSISPMRSISENS
230 240 250 260 270 280
380 390 400 410 420 430
pF1KB5 LVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTHGSPTASSQSSATNMAIHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTHGSPTASSQSSATNMAIHR
290 300 310 320 330 340
440 450 460 470 480 490
pF1KB5 SQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPVED
350 360 370 380 390 400
500 510 520 530 540
pF1KB5 DGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCARIAL
410 420 430 440 450
>>XP_016859388 (OMIM: 601524) PREDICTED: growth factor r (340 aa)
initn: 2312 init1: 2312 opt: 2312 Z-score: 2378.2 bits: 449.1 E(85289): 1e-125
Smith-Waterman score: 2312; 100.0% identity (100.0% similar) in 340 aa overlap (201-540:1-340)
180 190 200 210 220 230
pF1KB5 IEVLSNWGIEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLS
::::::::::::::::::::::::::::::
XP_016 MYFFPEHMVSFATETNGEISPTQILQMFLS
10 20 30
240 250 260 270 280 290
pF1KB5 SSTYPEIHGFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSTYPEIHGFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYV
40 50 60 70 80 90
300 310 320 330 340 350
pF1KB5 SLAGKKKHGAPTNYGFCFKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLAGKKKHGAPTNYGFCFKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNY
100 110 120 130 140 150
360 370 380 390 400 410
pF1KB5 MHPYQGRSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MHPYQGRSGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKG
160 170 180 190 200 210
420 430 440 450 460 470
pF1KB5 CLRLGTHGSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLRLGTHGSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQS
220 230 240 250 260 270
480 490 500 510 520 530
pF1KB5 NPKTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPKTFVLSMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCK
280 290 300 310 320 330
540
pF1KB5 LKHYCARIAL
::::::::::
XP_016 LKHYCARIAL
340
>>XP_011509324 (OMIM: 601524) PREDICTED: growth factor r (312 aa)
initn: 2103 init1: 2103 opt: 2103 Z-score: 2164.5 bits: 409.4 E(85289): 8e-114
Smith-Waterman score: 2103; 99.7% identity (100.0% similar) in 309 aa overlap (1-309:1-309)
10 20 30 40 50 60
pF1KB5 MTTSLQDGQSAASRAAARDSPLAAQVCGAAQGRGDAHDLAPAPWLHARALLPLPDGTRGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTTSLQDGQSAASRAAARDSPLAAQVCGAAQGRGDAHDLAPAPWLHARALLPLPDGTRGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AADRRKKKDLDVPEMPSIPNPFPELCCSPITSVLSADLFPKANSRKKQVIKVYSEDETSR
:::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
XP_011 AADRRKKKDLDVPEMPSIPNPFPELCCSPFTSVLSADLFPKANSRKKQVIKVYSEDETSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 ALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWGIE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIHGF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKHGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PTNYGFCFKPNKAGGPRDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGRSGC
:::::::::
XP_011 PTNYGFCFKVQA
310
>>XP_016867556 (OMIM: 601523) PREDICTED: growth factor r (536 aa)
initn: 1749 init1: 610 opt: 1952 Z-score: 2006.6 bits: 381.0 E(85289): 5e-105
Smith-Waterman score: 1952; 54.7% identity (78.5% similar) in 543 aa overlap (1-540:1-536)
10 20 30 40 50 60
pF1KB5 MTTSLQDGQSAASRAAARDSPLAAQVCGAAQGRGDAHDLAPAPWLHARALLPLPDGTRGC
:..::.. :: : . : . .: :... . : . : . . ..
XP_016 MNASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPRQRVQRSQPVHIL
10 20 30 40 50 60
70 80 90 100 110
pF1KB5 AADRRKKKD--LDVPEMPSIPNPFPELCCSPITSVLSADLFPKANSRKKQVIKVYSEDET
:. : ...: . . .:.::::::::: ::. .: ... :: .::.::: :
XP_016 AVRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 SRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWG
:..... .:.::::.::::. :.: .::.:::: :: ::.:.:: .::::::..: :.
XP_016 SKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVEST--
130 140 150 160 170
180 190 200 210 220 230
pF1KB5 IEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIH
. :.:. ::::::::::::::: ::::.::.. ..:: : ::.:: ::.::. :::.
XP_016 MASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNG--SQTQLLQNFLNSSSCPEIQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 GFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKH
::::.:: :::::::.: ::::::: :::::::::::::..... .:.:. .::.:..
XP_016 GFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFSLIAGRKQY
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 GAPTNYGFCFKPNKAGGP-RDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGR
.:::..:.:.::::. . ..:..::::.::.::::.::.::::::: ::::: : : :
XP_016 NAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQ-R
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 SGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTH
.. : .:.::.::::::::::::: .::::::.:: :.:.::: ::::.. :..
XP_016 KALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKRST-RMNIL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB5 GSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVL
:: . :. ... :::.: ::: .:::.:..:.: :::::::.::.::::::::.:::
XP_016 GSQSPLHPSTLSTV-IHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVL
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB5 SMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCAR
.. : ::::.:::.: ::::. : .::::.:.:.::::::.:::::::::::::::.: :
XP_016 TLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIR
480 490 500 510 520 530
540
pF1KB5 IAL
.::
XP_016 VAL
>>XP_016867557 (OMIM: 601523) PREDICTED: growth factor r (536 aa)
initn: 1749 init1: 610 opt: 1952 Z-score: 2006.6 bits: 381.0 E(85289): 5e-105
Smith-Waterman score: 1952; 54.7% identity (78.5% similar) in 543 aa overlap (1-540:1-536)
10 20 30 40 50 60
pF1KB5 MTTSLQDGQSAASRAAARDSPLAAQVCGAAQGRGDAHDLAPAPWLHARALLPLPDGTRGC
:..::.. :: : . : . .: :... . : . : . . ..
XP_016 MNASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPRQRVQRSQPVHIL
10 20 30 40 50 60
70 80 90 100 110
pF1KB5 AADRRKKKD--LDVPEMPSIPNPFPELCCSPITSVLSADLFPKANSRKKQVIKVYSEDET
:. : ...: . . .:.::::::::: ::. .: ... :: .::.::: :
XP_016 AVRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 SRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWG
:..... .:.::::.::::. :.: .::.:::: :: ::.:.:: .::::::..: :.
XP_016 SKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVEST--
130 140 150 160 170
180 190 200 210 220 230
pF1KB5 IEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIH
. :.:. ::::::::::::::: ::::.::.. ..:: : ::.:: ::.::. :::.
XP_016 MASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNG--SQTQLLQNFLNSSSCPEIQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 GFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKH
::::.:: :::::::.: ::::::: :::::::::::::..... .:.:. .::.:..
XP_016 GFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFSLIAGRKQY
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 GAPTNYGFCFKPNKAGGP-RDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGR
.:::..:.:.::::. . ..:..::::.::.::::.::.::::::: ::::: : : :
XP_016 NAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQ-R
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 SGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTH
.. : .:.::.::::::::::::: .::::::.:: :.:.::: ::::.. :..
XP_016 KALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKRST-RMNIL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB5 GSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVL
:: . :. ... :::.: ::: .:::.:..:.: :::::::.::.::::::::.:::
XP_016 GSQSPLHPSTLSTV-IHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVL
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB5 SMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCAR
.. : ::::.:::.: ::::. : .::::.:.:.::::::.:::::::::::::::.: :
XP_016 TLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIR
480 490 500 510 520 530
540
pF1KB5 IAL
.::
XP_016 VAL
>>NP_001001550 (OMIM: 601523) growth factor receptor-bou (536 aa)
initn: 1749 init1: 610 opt: 1952 Z-score: 2006.6 bits: 381.0 E(85289): 5e-105
Smith-Waterman score: 1952; 54.7% identity (78.5% similar) in 543 aa overlap (1-540:1-536)
10 20 30 40 50 60
pF1KB5 MTTSLQDGQSAASRAAARDSPLAAQVCGAAQGRGDAHDLAPAPWLHARALLPLPDGTRGC
:..::.. :: : . : . .: :... . : . : . . ..
NP_001 MNASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPRQRVQRSQPVHIL
10 20 30 40 50 60
70 80 90 100 110
pF1KB5 AADRRKKKD--LDVPEMPSIPNPFPELCCSPITSVLSADLFPKANSRKKQVIKVYSEDET
:. : ...: . . .:.::::::::: ::. .: ... :: .::.::: :
NP_001 AVRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 SRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWG
:..... .:.::::.::::. :.: .::.:::: :: ::.:.:: .::::::..: :.
NP_001 SKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVEST--
130 140 150 160 170
180 190 200 210 220 230
pF1KB5 IEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIH
. :.:. ::::::::::::::: ::::.::.. ..:: : ::.:: ::.::. :::.
NP_001 MASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNG--SQTQLLQNFLNSSSCPEIQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 GFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKH
::::.:: :::::::.: ::::::: :::::::::::::..... .:.:. .::.:..
NP_001 GFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFSLIAGRKQY
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 GAPTNYGFCFKPNKAGGP-RDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGR
.:::..:.:.::::. . ..:..::::.::.::::.::.::::::: ::::: : : :
NP_001 NAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQ-R
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 SGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTH
.. : .:.::.::::::::::::: .::::::.:: :.:.::: ::::.. :..
NP_001 KALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKRST-RMNIL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB5 GSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVL
:: . :. ... :::.: ::: .:::.:..:.: :::::::.::.::::::::.:::
NP_001 GSQSPLHPSTLSTV-IHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVL
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB5 SMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCAR
.. : ::::.:::.: ::::. : .::::.:.:.::::::.:::::::::::::::.: :
NP_001 TLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIR
480 490 500 510 520 530
540
pF1KB5 IAL
.::
NP_001 VAL
>>XP_016867554 (OMIM: 601523) PREDICTED: growth factor r (536 aa)
initn: 1749 init1: 610 opt: 1952 Z-score: 2006.6 bits: 381.0 E(85289): 5e-105
Smith-Waterman score: 1952; 54.7% identity (78.5% similar) in 543 aa overlap (1-540:1-536)
10 20 30 40 50 60
pF1KB5 MTTSLQDGQSAASRAAARDSPLAAQVCGAAQGRGDAHDLAPAPWLHARALLPLPDGTRGC
:..::.. :: : . : . .: :... . : . : . . ..
XP_016 MNASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPRQRVQRSQPVHIL
10 20 30 40 50 60
70 80 90 100 110
pF1KB5 AADRRKKKD--LDVPEMPSIPNPFPELCCSPITSVLSADLFPKANSRKKQVIKVYSEDET
:. : ...: . . .:.::::::::: ::. .: ... :: .::.::: :
XP_016 AVRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 SRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWG
:..... .:.::::.::::. :.: .::.:::: :: ::.:.:: .::::::..: :.
XP_016 SKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVEST--
130 140 150 160 170
180 190 200 210 220 230
pF1KB5 IEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIH
. :.:. ::::::::::::::: ::::.::.. ..:: : ::.:: ::.::. :::.
XP_016 MASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNG--SQTQLLQNFLNSSSCPEIQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 GFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKH
::::.:: :::::::.: ::::::: :::::::::::::..... .:.:. .::.:..
XP_016 GFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFSLIAGRKQY
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 GAPTNYGFCFKPNKAGGP-RDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGR
.:::..:.:.::::. . ..:..::::.::.::::.::.::::::: ::::: : : :
XP_016 NAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQ-R
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 SGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTH
.. : .:.::.::::::::::::: .::::::.:: :.:.::: ::::.. :..
XP_016 KALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKRST-RMNIL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB5 GSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVL
:: . :. ... :::.: ::: .:::.:..:.: :::::::.::.::::::::.:::
XP_016 GSQSPLHPSTLSTV-IHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVL
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB5 SMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCAR
.. : ::::.:::.: ::::. : .::::.:.:.::::::.:::::::::::::::.: :
XP_016 TLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIR
480 490 500 510 520 530
540
pF1KB5 IAL
.::
XP_016 VAL
>>XP_016867552 (OMIM: 601523) PREDICTED: growth factor r (536 aa)
initn: 1749 init1: 610 opt: 1952 Z-score: 2006.6 bits: 381.0 E(85289): 5e-105
Smith-Waterman score: 1952; 54.7% identity (78.5% similar) in 543 aa overlap (1-540:1-536)
10 20 30 40 50 60
pF1KB5 MTTSLQDGQSAASRAAARDSPLAAQVCGAAQGRGDAHDLAPAPWLHARALLPLPDGTRGC
:..::.. :: : . : . .: :... . : . : . . ..
XP_016 MNASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPRQRVQRSQPVHIL
10 20 30 40 50 60
70 80 90 100 110
pF1KB5 AADRRKKKD--LDVPEMPSIPNPFPELCCSPITSVLSADLFPKANSRKKQVIKVYSEDET
:. : ...: . . .:.::::::::: ::. .: ... :: .::.::: :
XP_016 AVRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 SRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWG
:..... .:.::::.::::. :.: .::.:::: :: ::.:.:: .::::::..: :.
XP_016 SKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVEST--
130 140 150 160 170
180 190 200 210 220 230
pF1KB5 IEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIH
. :.:. ::::::::::::::: ::::.::.. ..:: : ::.:: ::.::. :::.
XP_016 MASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNG--SQTQLLQNFLNSSSCPEIQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 GFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKH
::::.:: :::::::.: ::::::: :::::::::::::..... .:.:. .::.:..
XP_016 GFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFSLIAGRKQY
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 GAPTNYGFCFKPNKAGGP-RDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGR
.:::..:.:.::::. . ..:..::::.::.::::.::.::::::: ::::: : : :
XP_016 NAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQ-R
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 SGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTH
.. : .:.::.::::::::::::: .::::::.:: :.:.::: ::::.. :..
XP_016 KALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKRST-RMNIL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB5 GSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVL
:: . :. ... :::.: ::: .:::.:..:.: :::::::.::.::::::::.:::
XP_016 GSQSPLHPSTLSTV-IHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVL
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB5 SMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCAR
.. : ::::.:::.: ::::. : .::::.:.:.::::::.:::::::::::::::.: :
XP_016 TLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIR
480 490 500 510 520 530
540
pF1KB5 IAL
.::
XP_016 VAL
>>XP_016867553 (OMIM: 601523) PREDICTED: growth factor r (536 aa)
initn: 1749 init1: 610 opt: 1952 Z-score: 2006.6 bits: 381.0 E(85289): 5e-105
Smith-Waterman score: 1952; 54.7% identity (78.5% similar) in 543 aa overlap (1-540:1-536)
10 20 30 40 50 60
pF1KB5 MTTSLQDGQSAASRAAARDSPLAAQVCGAAQGRGDAHDLAPAPWLHARALLPLPDGTRGC
:..::.. :: : . : . .: :... . : . : . . ..
XP_016 MNASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPRQRVQRSQPVHIL
10 20 30 40 50 60
70 80 90 100 110
pF1KB5 AADRRKKKD--LDVPEMPSIPNPFPELCCSPITSVLSADLFPKANSRKKQVIKVYSEDET
:. : ...: . . .:.::::::::: ::. .: ... :: .::.::: :
XP_016 AVRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 SRALDVPSDITARDVCQLLILKNHYIDDHSWTLFEHLPHIGVERTIEDHELVIEVLSNWG
:..... .:.::::.::::. :.: .::.:::: :: ::.:.:: .::::::..: :.
XP_016 SKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVEST--
130 140 150 160 170
180 190 200 210 220 230
pF1KB5 IEEENKLYFRKNYAKYEFFKNPMYFFPEHMVSFATETNGEISPTQILQMFLSSSTYPEIH
. :.:. ::::::::::::::: ::::.::.. ..:: : ::.:: ::.::. :::.
XP_016 MASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNG--SQTQLLQNFLNSSSCPEIQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 GFLHAKEQGKKSWKKIYFFLRRSGLYFSTKGTSKEPRHLQFFSEFGNSDIYVSLAGKKKH
::::.:: :::::::.: ::::::: :::::::::::::..... .:.:. .::.:..
XP_016 GFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFSLIAGRKQY
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 GAPTNYGFCFKPNKAGGP-RDLKMLCAEEEQSRTCWVTAIRLLKYGMQLYQNYMHPYQGR
.:::..:.:.::::. . ..:..::::.::.::::.::.::::::: ::::: : : :
XP_016 NAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQ-R
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB5 SGCSSQSISPMRSISENSLVAMDFSGQKSRVIENPTEALSVAVEEGLAWRKKGCLRLGTH
.. : .:.::.::::::::::::: .::::::.:: :.:.::: ::::.. :..
XP_016 KALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKRST-RMNIL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB5 GSPTASSQSSATNMAIHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVL
:: . :. ... :::.: ::: .:::.:..:.: :::::::.::.::::::::.:::
XP_016 GSQSPLHPSTLSTV-IHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVL
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB5 SMSHGQKIKHFQIIPVEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNKGVLPCKLKHYCAR
.. : ::::.:::.: ::::. : .::::.:.:.::::::.:::::::::::::::.: :
XP_016 TLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIR
480 490 500 510 520 530
540
pF1KB5 IAL
.::
XP_016 VAL
540 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 10:44:37 2016 done: Sat Nov 5 10:44:38 2016
Total Scan time: 9.190 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]