Result of FASTA (omim) for
pFN21AB9843
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9843, 366 aa
1>>>pF1KB9843 366 - 366 aa - 366 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1132+/-0.00047; mu= 17.4770+/- 0.029
mean_var=93.8031+/-23.823, 0's: 0 Z-trim(109.1): 574 B-trim: 1879 in 2/51
Lambda= 0.132424
statistics sampled from 16541 (17247) to 16541 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.535), E-opt: 0.2 (0.202), width: 16
Scan time: 6.520
The best scores are: opt bits E(85289)
NP_001309137 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 2385 466.7 3.7e-131
XP_005264808 (OMIM: 182134) PREDICTED: 5-hydroxytr ( 366) 2385 466.7 3.7e-131
XP_011531966 (OMIM: 182134) PREDICTED: 5-hydroxytr ( 366) 2385 466.7 3.7e-131
NP_001309139 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 2385 466.7 3.7e-131
NP_000857 (OMIM: 182134) 5-hydroxytryptamine recep ( 366) 2385 466.7 3.7e-131
NP_001309138 (OMIM: 182134) 5-hydroxytryptamine re ( 366) 2385 466.7 3.7e-131
XP_011534091 (OMIM: 182132) PREDICTED: 5-hydroxytr ( 365) 1320 263.2 6.5e-70
NP_000856 (OMIM: 182132) 5-hydroxytryptamine recep ( 365) 1320 263.2 6.5e-70
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390) 1139 228.7 1.7e-59
NP_000855 (OMIM: 182133) 5-hydroxytryptamine recep ( 377) 1086 218.6 1.9e-56
NP_387512 (OMIM: 126451,181500,190300) D(3) dopami ( 367) 656 136.4 1e-31
NP_000515 (OMIM: 109760,614674) 5-hydroxytryptamin ( 422) 646 134.5 4.1e-31
NP_001307687 (OMIM: 601122) 5-hydroxytryptamine re ( 439) 571 120.2 8.7e-27
XP_006712545 (OMIM: 601122) PREDICTED: 5-hydroxytr ( 456) 571 120.3 9e-27
NP_000858 (OMIM: 601122) 5-hydroxytryptamine recep ( 481) 571 120.3 9.3e-27
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 566 119.3 1.8e-26
NP_062874 (OMIM: 182137) 5-hydroxytryptamine recep ( 432) 517 109.9 1.1e-23
NP_000863 (OMIM: 182137) 5-hydroxytryptamine recep ( 445) 517 109.9 1.1e-23
NP_062873 (OMIM: 182137) 5-hydroxytryptamine recep ( 479) 517 110.0 1.2e-23
XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B ad ( 328) 501 106.7 7.6e-23
XP_006714884 (OMIM: 104220) PREDICTED: alpha-1B ad ( 331) 501 106.7 7.7e-23
XP_005265875 (OMIM: 104220) PREDICTED: alpha-1B ad ( 366) 501 106.8 8.2e-23
XP_011532740 (OMIM: 104220) PREDICTED: alpha-1B ad ( 389) 501 106.8 8.5e-23
XP_011532739 (OMIM: 104220) PREDICTED: alpha-1B ad ( 402) 501 106.8 8.7e-23
NP_000670 (OMIM: 104220) alpha-1B adrenergic recep ( 520) 501 106.9 1e-22
XP_011532737 (OMIM: 104220) PREDICTED: alpha-1B ad ( 556) 501 107.0 1.1e-22
NP_076917 (OMIM: 601305) 5-hydroxytryptamine recep ( 357) 477 102.2 1.9e-21
NP_000674 (OMIM: 104250) alpha-2C adrenergic recep ( 462) 468 100.6 7.6e-21
NP_000672 (OMIM: 104210) alpha-2A adrenergic recep ( 465) 466 100.2 9.9e-21
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308) 462 99.2 1.3e-20
XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A ad ( 317) 462 99.3 1.3e-20
XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A ad ( 324) 462 99.3 1.3e-20
NP_001309433 (OMIM: 104221) alpha-1A adrenergic re ( 342) 462 99.3 1.4e-20
NP_001309432 (OMIM: 104221) alpha-1A adrenergic re ( 370) 462 99.3 1.4e-20
NP_001309431 (OMIM: 104221) alpha-1A adrenergic re ( 372) 462 99.3 1.5e-20
XP_006716356 (OMIM: 104221) PREDICTED: alpha-1A ad ( 429) 462 99.4 1.6e-20
NP_150645 (OMIM: 104221) alpha-1A adrenergic recep ( 429) 462 99.4 1.6e-20
NP_150647 (OMIM: 104221) alpha-1A adrenergic recep ( 455) 462 99.4 1.7e-20
NP_000671 (OMIM: 104221) alpha-1A adrenergic recep ( 466) 462 99.4 1.7e-20
NP_150646 (OMIM: 104221) alpha-1A adrenergic recep ( 475) 462 99.5 1.7e-20
XP_006716355 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 462 99.5 1.7e-20
XP_016868584 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 462 99.5 1.7e-20
XP_016868583 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 462 99.5 1.7e-20
XP_005246577 (OMIM: 601122) PREDICTED: 5-hydroxytr ( 362) 447 96.5 1e-19
NP_000673 (OMIM: 104260,607876) alpha-2B adrenergi ( 450) 436 94.5 5.2e-19
NP_000730 (OMIM: 118493) muscarinic acetylcholine ( 466) 428 92.9 1.5e-18
NP_001006629 (OMIM: 118493) muscarinic acetylcholi ( 466) 428 92.9 1.5e-18
XP_011514071 (OMIM: 118493) PREDICTED: muscarinic ( 466) 428 92.9 1.5e-18
NP_001006633 (OMIM: 118493) muscarinic acetylcholi ( 466) 428 92.9 1.5e-18
NP_001006632 (OMIM: 118493) muscarinic acetylcholi ( 466) 428 92.9 1.5e-18
>>NP_001309137 (OMIM: 182134) 5-hydroxytryptamine recept (366 aa)
initn: 2385 init1: 2385 opt: 2385 Z-score: 2475.8 bits: 466.7 E(85289): 3.7e-131
Smith-Waterman score: 2385; 100.0% identity (100.0% similar) in 366 aa overlap (1-366:1-366)
10 20 30 40 50 60
pF1KB9 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
310 320 330 340 350 360
pF1KB9 LVRCRC
::::::
NP_001 LVRCRC
>>XP_005264808 (OMIM: 182134) PREDICTED: 5-hydroxytrypta (366 aa)
initn: 2385 init1: 2385 opt: 2385 Z-score: 2475.8 bits: 466.7 E(85289): 3.7e-131
Smith-Waterman score: 2385; 100.0% identity (100.0% similar) in 366 aa overlap (1-366:1-366)
10 20 30 40 50 60
pF1KB9 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
310 320 330 340 350 360
pF1KB9 LVRCRC
::::::
XP_005 LVRCRC
>>XP_011531966 (OMIM: 182134) PREDICTED: 5-hydroxytrypta (366 aa)
initn: 2385 init1: 2385 opt: 2385 Z-score: 2475.8 bits: 466.7 E(85289): 3.7e-131
Smith-Waterman score: 2385; 100.0% identity (100.0% similar) in 366 aa overlap (1-366:1-366)
10 20 30 40 50 60
pF1KB9 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
310 320 330 340 350 360
pF1KB9 LVRCRC
::::::
XP_011 LVRCRC
>>NP_001309139 (OMIM: 182134) 5-hydroxytryptamine recept (366 aa)
initn: 2385 init1: 2385 opt: 2385 Z-score: 2475.8 bits: 466.7 E(85289): 3.7e-131
Smith-Waterman score: 2385; 100.0% identity (100.0% similar) in 366 aa overlap (1-366:1-366)
10 20 30 40 50 60
pF1KB9 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
310 320 330 340 350 360
pF1KB9 LVRCRC
::::::
NP_001 LVRCRC
>>NP_000857 (OMIM: 182134) 5-hydroxytryptamine receptor (366 aa)
initn: 2385 init1: 2385 opt: 2385 Z-score: 2475.8 bits: 466.7 E(85289): 3.7e-131
Smith-Waterman score: 2385; 100.0% identity (100.0% similar) in 366 aa overlap (1-366:1-366)
10 20 30 40 50 60
pF1KB9 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
310 320 330 340 350 360
pF1KB9 LVRCRC
::::::
NP_000 LVRCRC
>>NP_001309138 (OMIM: 182134) 5-hydroxytryptamine recept (366 aa)
initn: 2385 init1: 2385 opt: 2385 Z-score: 2475.8 bits: 466.7 E(85289): 3.7e-131
Smith-Waterman score: 2385; 100.0% identity (100.0% similar) in 366 aa overlap (1-366:1-366)
10 20 30 40 50 60
pF1KB9 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
310 320 330 340 350 360
pF1KB9 LVRCRC
::::::
NP_001 LVRCRC
>>XP_011534091 (OMIM: 182132) PREDICTED: 5-hydroxytrypta (365 aa)
initn: 1326 init1: 650 opt: 1320 Z-score: 1376.2 bits: 263.2 E(85289): 6.5e-70
Smith-Waterman score: 1320; 57.0% identity (80.0% similar) in 365 aa overlap (10-365:5-362)
10 20 30 40 50
pF1KB9 MDFLNSSDQNLTSEELLNRMPS----KILVSLTLSGLALMTTTINSLVIAAIIVTRKLHH
: :.: . :. :.:. .:: .. .:: .: :: :: .:.:::.
XP_011 MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 PANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSA
:::::::::::::.::::::::.::.::: . : .: .:..:::::.:::::::::: .
XP_011 PANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 IALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWR-HQGTSRD-DECII
:::::: :::.:.::::::: :.:..:: :: ::.:::::::::: :. : ..: :
XP_011 IALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 KHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASR-IAKEEVNGQVLLES
.:::.. :::::.:::::::.:::::::.::.:::.::.:: .:: .... ...: .
XP_011 QHDHVIYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQ----N
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 GEKSTKSVSTSYVLEKSLSDPSTDFDKIHSTVR--SLRSEFKHEKSWRRQKISGTRERKA
. : : ..: : . : :::.:.:.:.:...: . ... : .::.::.::::::
XP_011 SFASCKLTQTFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPG--ERQQISSTRERKA
240 250 260 270 280
300 310 320 330 340 350
pF1KB9 ATTLGLILGAFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFN
: ::::::::.. :::::.:::.:.. . .: :...::.::::.:::::::.:: ::
XP_011 ARILGLILGAFILSWLPFFIKELIVGL-SIYTVSSEVADFLTWLGYVNSLINPLLYTSFN
290 300 310 320 330 340
360
pF1KB9 EDFKKAFQKLVRCRC
:::: ::.::.:::
XP_011 EDFKLAFKKLIRCREHT
350 360
>>NP_000856 (OMIM: 182132) 5-hydroxytryptamine receptor (365 aa)
initn: 1326 init1: 650 opt: 1320 Z-score: 1376.2 bits: 263.2 E(85289): 6.5e-70
Smith-Waterman score: 1320; 57.0% identity (80.0% similar) in 365 aa overlap (10-365:5-362)
10 20 30 40 50
pF1KB9 MDFLNSSDQNLTSEELLNRMPS----KILVSLTLSGLALMTTTINSLVIAAIIVTRKLHH
: :.: . :. :.:. .:: .. .:: .: :: :: .:.:::.
NP_000 MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 PANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSA
:::::::::::::.::::::::.::.::: . : .: .:..:::::.:::::::::: .
NP_000 PANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 IALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWR-HQGTSRD-DECII
:::::: :::.:.::::::: :.:..:: :: ::.:::::::::: :. : ..: :
NP_000 IALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 KHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASR-IAKEEVNGQVLLES
.:::.. :::::.:::::::.:::::::.::.:::.::.:: .:: .... ...: .
NP_000 QHDHVIYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQ----N
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 GEKSTKSVSTSYVLEKSLSDPSTDFDKIHSTVR--SLRSEFKHEKSWRRQKISGTRERKA
. : : ..: : . : :::.:.:.:.:...: . ... : .::.::.::::::
NP_000 SFASCKLTQTFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPG--ERQQISSTRERKA
240 250 260 270 280
300 310 320 330 340 350
pF1KB9 ATTLGLILGAFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFN
: ::::::::.. :::::.:::.:.. . .: :...::.::::.:::::::.:: ::
NP_000 ARILGLILGAFILSWLPFFIKELIVGL-SIYTVSSEVADFLTWLGYVNSLINPLLYTSFN
290 300 310 320 330 340
360
pF1KB9 EDFKKAFQKLVRCRC
:::: ::.::.:::
NP_000 EDFKLAFKKLIRCREHT
350 360
>>NP_000854 (OMIM: 182131) 5-hydroxytryptamine receptor (390 aa)
initn: 1109 init1: 617 opt: 1139 Z-score: 1188.9 bits: 228.7 E(85289): 1.7e-59
Smith-Waterman score: 1139; 48.2% identity (75.6% similar) in 365 aa overlap (5-366:32-388)
10 20 30
pF1KB9 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLA
: : .. .. .. .: :.:. . :. ..
NP_000 EEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSIS-LPWKVLLVMLLALIT
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB9 LMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQV
: :: :..:::.. ::::: :::::: ::::::.::..::::.: .: : : .:::
NP_000 LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 VCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFI
:::.::: :::::: ::::: .:::::: ::::::::. :::::.:..::..::..:. :
NP_000 VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB9 SMPPLFWRHQGTSRD-DECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYH
:.::.:::. . .. .::... :::. :.::: ::::.: :.. :: .:: :..
NP_000 SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB9 KRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSD-PSTDFDKIHSTVRSLRSEF
:. .: .:. . .:.. .: ::.::.. ... . : :: . . .. . ..:
NP_000 KQTPNRTGKRLTRAQLITDS-PGSTSSVTS---INSRVPDVPSESGSPVYVNQVKVRVS-
250 260 270 280 290
280 290 300 310 320 330
pF1KB9 KHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVC-DKCKISEEMSNF
. ...:. ..:::::. :::.:::::..::::::. ::. .: : : . . .:
NP_000 --DALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDF
300 310 320 330 340 350
340 350 360
pF1KB9 LAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC
..:::::::::::.:::. :::::.::.::.: .:
NP_000 FTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
360 370 380 390
>>NP_000855 (OMIM: 182133) 5-hydroxytryptamine receptor (377 aa)
initn: 1050 init1: 591 opt: 1086 Z-score: 1134.4 bits: 218.6 E(85289): 1.9e-56
Smith-Waterman score: 1086; 50.4% identity (77.4% similar) in 345 aa overlap (23-365:38-374)
10 20 30 40 50
pF1KB9 MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTR
:: ....:: ..: :. :..:...:..::
NP_000 AEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVLTTILLTR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 KLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSIL
::: :::::: :::.::.::..::::.::.: . ..: .::..:::::: :::::: :::
NP_000 KLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDITCCTASIL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 HLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRD-DE
:: .:::::: :::::.::...:: ::. ::.::: ::. ::.::::::. .... ..
NP_000 HLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAKAQEEMSD
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 CIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLL
:... ..: ::::: :::::: .:..::: .:::::.. . : .:. ......
NP_000 CLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILN-PPSLYGKRFTTAHLIT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 ESGEKSTKSVSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKA
:. .: :...: .: : : : . : .. : .. :..::..:::::
NP_000 GSAGSSLCSLNSSLHEGHSHSAGSPLFFN-HVKIKLADSALE------RKRISAARERKA
250 260 270 280 290
300 310 320 330 340 350
pF1KB9 ATTLGLILGAFVICWLPFFVKELVVNVC-DKCKISEEMSNFLAWLGYLNSLINPLIYTIF
. ::.:::::.:::::::: ::. .: :.: : . .:..:::::::::::.:::.:
NP_000 TKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVF
300 310 320 330 340 350
360
pF1KB9 NEDFKKAFQKLVRCRC
::.:..::::.: :
NP_000 NEEFRQAFQKIVPFRKAS
360 370
366 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 19:40:50 2016 done: Fri Nov 4 19:40:51 2016
Total Scan time: 6.520 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]