Result of FASTA (omim) for
pFN21AB9791
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9791, 210 aa
1>>>pF1KB9791 210 - 210 aa - 210 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7230+/-0.000256; mu= 8.5702+/- 0.016
mean_var=110.1372+/-22.068, 0's: 0 Z-trim(123.4): 30 B-trim: 0 in 0/54
Lambda= 0.122210
statistics sampled from 43080 (43110) to 43080 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.82), E-opt: 0.2 (0.505), width: 16
Scan time: 7.400
The best scores are: opt bits E(85289)
XP_005259019 (OMIM: 162662,613100) PREDICTED: neur ( 210) 1451 265.2 5.4e-71
NP_006170 (OMIM: 162662,613100) neurotrophin-4 pre ( 210) 1451 265.2 5.4e-71
XP_011525312 (OMIM: 162662,613100) PREDICTED: neur ( 210) 1451 265.2 5.4e-71
XP_006723295 (OMIM: 162662,613100) PREDICTED: neur ( 210) 1451 265.2 5.4e-71
XP_011525311 (OMIM: 162662,613100) PREDICTED: neur ( 210) 1451 265.2 5.4e-71
XP_011525310 (OMIM: 162662,613100) PREDICTED: neur ( 220) 1451 265.2 5.6e-71
NP_002518 (OMIM: 162660) neurotrophin-3 isoform 2 ( 257) 502 98.0 1.5e-20
XP_011519265 (OMIM: 162660) PREDICTED: neurotrophi ( 257) 502 98.0 1.5e-20
NP_001096124 (OMIM: 162660) neurotrophin-3 isoform ( 270) 502 98.0 1.6e-20
NP_001137277 (OMIM: 113505,164230,209880,607499,61 ( 247) 475 93.2 3.9e-19
NP_001137280 (OMIM: 113505,164230,209880,607499,61 ( 247) 475 93.2 3.9e-19
NP_001137284 (OMIM: 113505,164230,209880,607499,61 ( 247) 475 93.2 3.9e-19
NP_001137278 (OMIM: 113505,164230,209880,607499,61 ( 247) 475 93.2 3.9e-19
NP_733929 (OMIM: 113505,164230,209880,607499,61026 ( 247) 475 93.2 3.9e-19
NP_733931 (OMIM: 113505,164230,209880,607499,61026 ( 247) 475 93.2 3.9e-19
NP_001137288 (OMIM: 113505,164230,209880,607499,61 ( 247) 475 93.2 3.9e-19
NP_733928 (OMIM: 113505,164230,209880,607499,61026 ( 247) 475 93.2 3.9e-19
NP_001137285 (OMIM: 113505,164230,209880,607499,61 ( 247) 475 93.2 3.9e-19
NP_001137286 (OMIM: 113505,164230,209880,607499,61 ( 247) 475 93.2 3.9e-19
NP_001137279 (OMIM: 113505,164230,209880,607499,61 ( 247) 475 93.2 3.9e-19
NP_001700 (OMIM: 113505,164230,209880,607499,61026 ( 247) 475 93.2 3.9e-19
NP_001137283 (OMIM: 113505,164230,209880,607499,61 ( 247) 475 93.2 3.9e-19
NP_733927 (OMIM: 113505,164230,209880,607499,61026 ( 255) 475 93.2 4e-19
NP_733930 (OMIM: 113505,164230,209880,607499,61026 ( 262) 475 93.2 4.1e-19
NP_001137281 (OMIM: 113505,164230,209880,607499,61 ( 276) 475 93.2 4.3e-19
NP_001137282 (OMIM: 113505,164230,209880,607499,61 ( 329) 475 93.3 5e-19
XP_011518582 (OMIM: 113505,164230,209880,607499,61 ( 329) 475 93.3 5e-19
XP_006710726 (OMIM: 162030,608654) PREDICTED: beta ( 241) 371 74.8 1.3e-13
NP_002497 (OMIM: 162030,608654) beta-nerve growth ( 241) 371 74.8 1.3e-13
XP_011539820 (OMIM: 162030,608654) PREDICTED: beta ( 296) 371 74.9 1.5e-13
>>XP_005259019 (OMIM: 162662,613100) PREDICTED: neurotro (210 aa)
initn: 1451 init1: 1451 opt: 1451 Z-score: 1395.5 bits: 265.2 E(85289): 5.4e-71
Smith-Waterman score: 1451; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210)
10 20 30 40 50 60
pF1KB9 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRAL
130 140 150 160 170 180
190 200 210
pF1KB9 TADAQGRVGWRWIRIDTACVCTLLSRTGRA
::::::::::::::::::::::::::::::
XP_005 TADAQGRVGWRWIRIDTACVCTLLSRTGRA
190 200 210
>>NP_006170 (OMIM: 162662,613100) neurotrophin-4 preprop (210 aa)
initn: 1451 init1: 1451 opt: 1451 Z-score: 1395.5 bits: 265.2 E(85289): 5.4e-71
Smith-Waterman score: 1451; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210)
10 20 30 40 50 60
pF1KB9 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRAL
130 140 150 160 170 180
190 200 210
pF1KB9 TADAQGRVGWRWIRIDTACVCTLLSRTGRA
::::::::::::::::::::::::::::::
NP_006 TADAQGRVGWRWIRIDTACVCTLLSRTGRA
190 200 210
>>XP_011525312 (OMIM: 162662,613100) PREDICTED: neurotro (210 aa)
initn: 1451 init1: 1451 opt: 1451 Z-score: 1395.5 bits: 265.2 E(85289): 5.4e-71
Smith-Waterman score: 1451; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210)
10 20 30 40 50 60
pF1KB9 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRAL
130 140 150 160 170 180
190 200 210
pF1KB9 TADAQGRVGWRWIRIDTACVCTLLSRTGRA
::::::::::::::::::::::::::::::
XP_011 TADAQGRVGWRWIRIDTACVCTLLSRTGRA
190 200 210
>>XP_006723295 (OMIM: 162662,613100) PREDICTED: neurotro (210 aa)
initn: 1451 init1: 1451 opt: 1451 Z-score: 1395.5 bits: 265.2 E(85289): 5.4e-71
Smith-Waterman score: 1451; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210)
10 20 30 40 50 60
pF1KB9 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRAL
130 140 150 160 170 180
190 200 210
pF1KB9 TADAQGRVGWRWIRIDTACVCTLLSRTGRA
::::::::::::::::::::::::::::::
XP_006 TADAQGRVGWRWIRIDTACVCTLLSRTGRA
190 200 210
>>XP_011525311 (OMIM: 162662,613100) PREDICTED: neurotro (210 aa)
initn: 1451 init1: 1451 opt: 1451 Z-score: 1395.5 bits: 265.2 E(85289): 5.4e-71
Smith-Waterman score: 1451; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210)
10 20 30 40 50 60
pF1KB9 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRAL
130 140 150 160 170 180
190 200 210
pF1KB9 TADAQGRVGWRWIRIDTACVCTLLSRTGRA
::::::::::::::::::::::::::::::
XP_011 TADAQGRVGWRWIRIDTACVCTLLSRTGRA
190 200 210
>>XP_011525310 (OMIM: 162662,613100) PREDICTED: neurotro (220 aa)
initn: 1451 init1: 1451 opt: 1451 Z-score: 1395.2 bits: 265.2 E(85289): 5.6e-71
Smith-Waterman score: 1451; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:11-220)
10 20 30 40 50
pF1KB9 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSR
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRHHTRVLREMLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 GAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 VDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSEC
130 140 150 160 170 180
180 190 200 210
pF1KB9 KAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRA
::::::::::::::::::::::::::::::::::::::::
XP_011 KAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRA
190 200 210 220
>>NP_002518 (OMIM: 162660) neurotrophin-3 isoform 2 prep (257 aa)
initn: 602 init1: 268 opt: 502 Z-score: 489.9 bits: 98.0 E(85289): 1.5e-20
Smith-Waterman score: 578; 46.3% identity (69.2% similar) in 201 aa overlap (18-209:69-256)
10 20 30 40
pF1KB9 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLL-----
: : .. : :.. : .: . .::
NP_002 IQADILKNKLSKQMVDVKENYQSTLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRR
40 50 60 70 80 90
50 60 70 80 90
pF1KB9 --SPRVVLSRGAPAGPPLLFLLEAGAFRESAGAP--ANRSRRGVSETAPASRRGELAVCD
::::.:: ..: :: :.:.: . .:.: :::. : . :.::: .:::
NP_002 YNSPRVLLSDSTPLEPPPLYLME-----DYVGSPVVANRTSRRKRYAEHKSHRGEYSVCD
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB9 AVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGC
. : ::::. .:.:.::..: ::::. . :.::..:::.::::: :. : .: :
NP_002 SESLWVTDKSSAIDIRGHQVTVLGEIKT-GNSPVKQYFYETRCK-----EARPVKNG--C
160 170 180 190 200
160 170 180 190 200 210
pF1KB9 RGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRA
::.: .:: :.::..:.::::::.. . ::::::::::.:::.: . ::
NP_002 RGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGRT
210 220 230 240 250
>>XP_011519265 (OMIM: 162660) PREDICTED: neurotrophin-3 (257 aa)
initn: 602 init1: 268 opt: 502 Z-score: 489.9 bits: 98.0 E(85289): 1.5e-20
Smith-Waterman score: 578; 46.3% identity (69.2% similar) in 201 aa overlap (18-209:69-256)
10 20 30 40
pF1KB9 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLL-----
: : .. : :.. : .: . .::
XP_011 IQADILKNKLSKQMVDVKENYQSTLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRR
40 50 60 70 80 90
50 60 70 80 90
pF1KB9 --SPRVVLSRGAPAGPPLLFLLEAGAFRESAGAP--ANRSRRGVSETAPASRRGELAVCD
::::.:: ..: :: :.:.: . .:.: :::. : . :.::: .:::
XP_011 YNSPRVLLSDSTPLEPPPLYLME-----DYVGSPVVANRTSRRKRYAEHKSHRGEYSVCD
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB9 AVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGC
. : ::::. .:.:.::..: ::::. . :.::..:::.::::: :. : .: :
XP_011 SESLWVTDKSSAIDIRGHQVTVLGEIKT-GNSPVKQYFYETRCK-----EARPVKNG--C
160 170 180 190 200
160 170 180 190 200 210
pF1KB9 RGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRA
::.: .:: :.::..:.::::::.. . ::::::::::.:::.: . ::
XP_011 RGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGRT
210 220 230 240 250
>>NP_001096124 (OMIM: 162660) neurotrophin-3 isoform 1 p (270 aa)
initn: 586 init1: 268 opt: 502 Z-score: 489.6 bits: 98.0 E(85289): 1.6e-20
Smith-Waterman score: 578; 46.3% identity (69.2% similar) in 201 aa overlap (18-209:82-269)
10 20 30 40
pF1KB9 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLL-----
: : .. : :.. : .: . .::
NP_001 IQADILKNKLSKQMVDVKENYQSTLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRR
60 70 80 90 100 110
50 60 70 80 90
pF1KB9 --SPRVVLSRGAPAGPPLLFLLEAGAFRESAGAP--ANRSRRGVSETAPASRRGELAVCD
::::.:: ..: :: :.:.: . .:.: :::. : . :.::: .:::
NP_001 YNSPRVLLSDSTPLEPPPLYLME-----DYVGSPVVANRTSRRKRYAEHKSHRGEYSVCD
120 130 140 150 160
100 110 120 130 140 150
pF1KB9 AVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGC
. : ::::. .:.:.::..: ::::. . :.::..:::.::::: :. : .: :
NP_001 SESLWVTDKSSAIDIRGHQVTVLGEIKT-GNSPVKQYFYETRCK-----EARPVKNG--C
170 180 190 200 210
160 170 180 190 200 210
pF1KB9 RGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRA
::.: .:: :.::..:.::::::.. . ::::::::::.:::.: . ::
NP_001 RGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGRT
220 230 240 250 260 270
>>NP_001137277 (OMIM: 113505,164230,209880,607499,610269 (247 aa)
initn: 480 init1: 284 opt: 475 Z-score: 464.5 bits: 93.2 E(85289): 3.9e-19
Smith-Waterman score: 547; 51.7% identity (70.9% similar) in 172 aa overlap (40-209:88-247)
10 20 30 40 50 60
pF1KB9 PILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLFLLEAGAFRE
:: . ::.:: .: :::::::: ...
NP_001 SLADTFEHVIEELLDEDQKVRPNEENNKDADLYTSRVMLSSQVPLEPPLLFLLE--EYKN
60 70 80 90 100 110
70 80 90 100 110 120
pF1KB9 SAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVT--DRRTAVDLRGREVEVLGEVPAA
: :: : : .. :: :::::.:::..: ::: :..::::. : : :: .::..
NP_001 YLDA-ANMSMRVRRHSDPA-RRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVS
120 130 140 150 160 170
130 140 150 160 170 180
pF1KB9 GGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGR
:. :.:::.::.:. : ::::.:.::: :.:.. :::::::: :.. :
NP_001 KGQ-LKQYFYETKCNP-------MGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKR
180 190 200 210 220
190 200 210
pF1KB9 VGWRWIRIDTACVCTLLSRTGRA
.:::.:::::.::::: . ::
NP_001 IGWRFIRIDTSCVCTLTIKRGR
230 240
210 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:58:06 2016 done: Fri Nov 4 18:58:07 2016
Total Scan time: 7.400 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]