Result of FASTA (omim) for
pFN21AB9785
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9785, 189 aa
1>>>pF1KB9785 189 - 189 aa - 189 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0446+/-0.000364; mu= 14.2530+/- 0.023
mean_var=64.5102+/-12.234, 0's: 0 Z-trim(113.6): 20 B-trim: 0 in 0/51
Lambda= 0.159683
statistics sampled from 23024 (23041) to 23024 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.27), width: 16
Scan time: 5.590
The best scores are: opt bits E(85289)
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189) 1251 296.7 1.5e-80
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190) 1246 295.5 3.4e-80
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189) 1064 253.6 1.4e-67
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189) 1037 247.4 1e-65
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189) 1033 246.4 2e-65
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189) 1001 239.1 3.3e-63
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189) 995 237.7 8.5e-63
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188) 994 237.5 1e-62
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189) 985 235.4 4.2e-62
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189) 985 235.4 4.2e-62
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189) 958 229.2 3.1e-60
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189) 939 224.8 6.5e-59
NP_002161 (OMIM: 147568) interferon alpha-8 precur ( 189) 917 219.7 2.2e-57
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195) 667 162.1 4.9e-40
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208) 383 96.7 2.6e-20
NP_002167 (OMIM: 147640) interferon beta precursor ( 187) 310 79.9 2.7e-15
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 162 45.8 5.4e-05
>>NP_076918 (OMIM: 147660) interferon alpha-1/13 precurs (189 aa)
initn: 1251 init1: 1251 opt: 1251 Z-score: 1567.1 bits: 296.7 E(85289): 1.5e-80
Smith-Waterman score: 1251; 100.0% identity (100.0% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB9 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
130 140 150 160 170 180
pF1KB9 LQERLRRKE
:::::::::
NP_076 LQERLRRKE
>>NP_008831 (OMIM: 147578) interferon alpha-1/13 precurs (190 aa)
initn: 1246 init1: 1246 opt: 1246 Z-score: 1560.8 bits: 295.5 E(85289): 3.4e-80
Smith-Waterman score: 1246; 99.5% identity (100.0% similar) in 189 aa overlap (1-189:2-190)
10 20 30 40 50
pF1KB9 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
:::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MMASPFALLMALVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
130 140 150 160 170 180
180
pF1KB9 NLQERLRRKE
::::::::::
NP_008 NLQERLRRKE
190
>>NP_002160 (OMIM: 147565) interferon alpha-5 precursor (189 aa)
initn: 1064 init1: 1064 opt: 1064 Z-score: 1334.3 bits: 253.6 E(85289): 1.4e-67
Smith-Waterman score: 1064; 84.1% identity (94.2% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB9 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
:: ::.:::.::::.::: ::::::::.::::.::::::..:::.:::: ::: ::::::
NP_002 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
:::::::::::::: :::::::.::: ::::.::::::.::: ::::: :::::::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
::.::: : .:::::.::::.:.:::.::::::::::::::::::::::::::.:::.:
NP_002 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
130 140 150 160 170 180
pF1KB9 LQERLRRKE
:::::::::
NP_002 LQERLRRKE
>>NP_066282 (OMIM: 147566) interferon alpha-6 precursor (189 aa)
initn: 1037 init1: 1037 opt: 1037 Z-score: 1300.7 bits: 247.4 E(85289): 1e-65
Smith-Waterman score: 1037; 84.7% identity (90.5% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB9 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
:: ::::::.:::::::::::: ::::.:::: .:::.:::::: ::: ::: :::::
NP_066 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
:::::::::::::: :::::::.::: ::::.:::::.:::: ::::. :::::::::::
NP_066 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
:::::: :: ::::: ::::::.:::.::::::::::::::::::::::::::.: : :
NP_066 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
130 140 150 160 170 180
pF1KB9 LQERLRRKE
:::::::::
NP_066 LQERLRRKE
>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor (189 aa)
initn: 1092 init1: 1033 opt: 1033 Z-score: 1295.7 bits: 246.4 E(85289): 2e-65
Smith-Waterman score: 1033; 82.0% identity (91.5% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB9 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
:: ::::.:.::::::::::::::.: .::::.:::::::.::: :::: ::: :::::
NP_002 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
:::::::::::::: :::::::..:: ::::.::.::::::: ::.:: ::.::.::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
:::.:: : :::::: ::::::::::.:::::: :::::::::::::::::::::.:::
NP_002 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KB9 LQERLRRKE
::.:::::.
NP_002 LQKRLRRKD
>>NP_002166 (OMIM: 147584) interferon alpha-21 precursor (189 aa)
initn: 1001 init1: 1001 opt: 1001 Z-score: 1255.8 bits: 239.1 E(85289): 3.3e-63
Smith-Waterman score: 1001; 81.0% identity (91.5% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB9 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
:: :.:::...::: :: ::::::::.:::: :::.:.:::::.:::: ::: ::::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
:::::::::::::: :::::::.::: ::::.::::::.:...::.:: ::: :::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
:::.:: : ::::::.::::::::::.::::::::::::::::::::::::::.:::
NP_002 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
130 140 150 160 170 180
pF1KB9 LQERLRRKE
.::::::::
NP_002 FQERLRRKE
>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor (189 aa)
initn: 1010 init1: 995 opt: 995 Z-score: 1248.4 bits: 237.7 E(85289): 8.5e-63
Smith-Waterman score: 995; 79.9% identity (92.1% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB9 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
:: :.:::...::: :: ::::::::.:::: :::.:.:::::.::: ::: ::::::
NP_066 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
::.:::::.::::: :::::::.::: ::::.:.::::::...::.:: :::::::::::
NP_066 FPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
:::.:: : :::::: ::::::.:::.::::::::::::::::::::::::::::.:::
NP_066 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KB9 LQERLRRKE
::.:::::.
NP_066 LQKRLRRKD
>>NP_000596 (OMIM: 147562) interferon alpha-2 precursor (188 aa)
initn: 992 init1: 650 opt: 994 Z-score: 1247.1 bits: 237.5 E(85289): 1e-62
Smith-Waterman score: 994; 82.0% identity (89.4% similar) in 189 aa overlap (1-189:1-188)
10 20 30 40 50 60
pF1KB9 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
:: ::::..:.:::::::::.:::::.:::: .:::::::::: ::: ::: ::::::
NP_000 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
:::::: ::::::: .: ::::.::::::::.:::::::::: ::::: :::::::::::
NP_000 FPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLE
70 80 90 100 110
130 140 150 160 170 180
pF1KB9 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
:::.: : :::::. ::::::.:::.:::::: :::::::::::::::::::.:::::
NP_000 ACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTN
120 130 140 150 160 170
pF1KB9 LQERLRRKE
::: :: ::
NP_000 LQESLRSKE
180
>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor (189 aa)
initn: 1005 init1: 985 opt: 985 Z-score: 1235.9 bits: 235.4 E(85289): 4.2e-62
Smith-Waterman score: 985; 78.8% identity (92.1% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB9 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
:: :.:::...::: :: ::::::::.:::: :::.:.:::::.:::: ::: ::::::
NP_067 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
.::::::::::::. :::::::.::: ::::.:.::::::...::.:: ::::::::.::
NP_067 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
:::.:: . :::::: ::::::.:::.::::::::::::::::::::::::::::.:::
NP_067 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KB9 LQERLRRKE
::. ::::.
NP_067 LQKILRRKD
>>NP_002162 (OMIM: 147577) interferon alpha-10 precursor (189 aa)
initn: 1000 init1: 985 opt: 985 Z-score: 1235.9 bits: 235.4 E(85289): 4.2e-62
Smith-Waterman score: 985; 78.8% identity (91.5% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KB9 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFG
:: :.:::...::: :: ::::::::.:::: :::.:.::.::.:::: ::: :::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLE
.::::::::::::: :::::::.::: ::::.:.::::::...::.:: :::::::::::
NP_002 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 ACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTN
:::.:: : :::::: ::::::.:::.:::::: :.:::::::::::::::::::.:::
NP_002 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KB9 LQERLRRKE
::.:::::.
NP_002 LQKRLRRKD
189 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:54:54 2016 done: Fri Nov 4 18:54:55 2016
Total Scan time: 5.590 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]