Result of FASTA (omim) for
pFN21AB9580
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9580, 181 aa
1>>>pF1KB9580 181 - 181 aa - 181 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0613+/-0.000304; mu= 10.3648+/- 0.019
mean_var=93.5608+/-18.968, 0's: 0 Z-trim(119.7): 62 B-trim: 393 in 2/55
Lambda= 0.132595
statistics sampled from 33978 (34045) to 33978 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.399), width: 16
Scan time: 5.360
The best scores are: opt bits E(85289)
NP_065697 (OMIM: 609154) achaete-scute homolog 3 [ ( 181) 1247 247.7 7.7e-66
NP_982260 (OMIM: 609155) achaete-scute homolog 4 [ ( 173) 308 68.1 8.7e-12
NP_004307 (OMIM: 100790,209880) achaete-scute homo ( 236) 222 51.7 1e-06
NP_005161 (OMIM: 601886) achaete-scute homolog 2 [ ( 193) 213 49.9 2.8e-06
NP_835455 (OMIM: 607194,609069,615935) pancreas tr ( 328) 178 43.4 0.00045
NP_001277335 (OMIM: 187040,613065) T-cell acute ly ( 172) 161 39.9 0.0025
XP_016857682 (OMIM: 187040,613065) PREDICTED: T-ce ( 172) 161 39.9 0.0025
XP_005259969 (OMIM: 151440) PREDICTED: protein lyl ( 206) 161 40.0 0.0029
NP_005574 (OMIM: 151440) protein lyl-1 [Homo sapie ( 280) 161 40.1 0.0037
NP_068808 (OMIM: 602407) heart- and neural crest d ( 217) 159 39.6 0.004
XP_016882306 (OMIM: 151440) PREDICTED: protein lyl ( 302) 161 40.1 0.004
NP_004600 (OMIM: 601010) transcription factor 15 [ ( 199) 158 39.4 0.0042
XP_016857679 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 161 40.1 0.0043
NP_001274276 (OMIM: 187040,613065) T-cell acute ly ( 331) 161 40.1 0.0043
XP_016857676 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 161 40.1 0.0043
NP_001277332 (OMIM: 187040,613065) T-cell acute ly ( 331) 161 40.1 0.0043
NP_001277334 (OMIM: 187040,613065) T-cell acute ly ( 331) 161 40.1 0.0043
NP_003180 (OMIM: 187040,613065) T-cell acute lymph ( 331) 161 40.1 0.0043
XP_005271217 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 161 40.1 0.0043
NP_001277333 (OMIM: 187040,613065) T-cell acute ly ( 331) 161 40.1 0.0043
XP_016857677 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 161 40.1 0.0043
XP_016857678 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 161 40.1 0.0043
XP_016857680 (OMIM: 187040,613065) PREDICTED: T-ce ( 331) 161 40.1 0.0043
NP_005412 (OMIM: 186855,613065) T-cell acute lymph ( 108) 154 38.5 0.0044
XP_016882305 (OMIM: 151440) PREDICTED: protein lyl ( 351) 161 40.1 0.0045
NP_476527 (OMIM: 200110,209885,227260,607556) twis ( 160) 156 39.0 0.0046
NP_001258822 (OMIM: 200110,209885,227260,607556) t ( 160) 156 39.0 0.0046
NP_001004311 (OMIM: 608697,612310) factor in the g ( 219) 153 38.5 0.0089
NP_000465 (OMIM: 101400,123100,180750,601622) twis ( 202) 152 38.3 0.0095
XP_011513798 (OMIM: 101400,123100,180750,601622) P ( 202) 152 38.3 0.0095
>>NP_065697 (OMIM: 609154) achaete-scute homolog 3 [Homo (181 aa)
initn: 1247 init1: 1247 opt: 1247 Z-score: 1303.1 bits: 247.7 E(85289): 7.7e-66
Smith-Waterman score: 1247; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181)
10 20 30 40 50 60
pF1KB9 MMDNRGNSSLPDKLPIFPDSARLPLTRSFYLEPMVTFHVHPEAPVSSPYSEELPRLPFPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MMDNRGNSSLPDKLPIFPDSARLPLTRSFYLEPMVTFHVHPEAPVSSPYSEELPRLPFPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 DSLILGNYSEPCPFSFPMPYPNYRGCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DSLILGNYSEPCPFSFPMPYPNYRGCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHHL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 PEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRI
130 140 150 160 170 180
pF1KB9 V
:
NP_065 V
>>NP_982260 (OMIM: 609155) achaete-scute homolog 4 [Homo (173 aa)
initn: 320 init1: 300 opt: 308 Z-score: 332.6 bits: 68.1 E(85289): 8.7e-12
Smith-Waterman score: 308; 47.3% identity (61.2% similar) in 129 aa overlap (22-149:10-129)
10 20 30 40 50 60
pF1KB9 MMDNRGNSSLPDKLPIFPDSARLPLTRSFYLEPMVTFHVHPEAPVSSPYSEELPRLPFPS
:: : :. :. . . : : .: : ::
NP_982 MMETRKPAERLALPYSLRTAPLGVPGTLPGLPRRDPLRVAL-RL----
10 20 30 40
70 80 90 100 110
pF1KB9 DSLILGNYSEPCPFSFP-MPYPNYRGCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHH
:. : .. .: : . .. ::: :::::::::::.:::::::.:: :
NP_982 DAACWEWARSGCARGWQYLPVP----LDSAFEPAFLRKRNERERQRVRCVNEGYARLRDH
50 60 70 80 90
120 130 140 150 160 170
pF1KB9 LPEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFR
::.: .::::::::::::: ::..:: ::
NP_982 LPRELADKRLSKVETLRAAIDYIKHLQELLERQAWGLEGAAGAVPQRRAECNSDGESKAS
100 110 120 130 140 150
>>NP_004307 (OMIM: 100790,209880) achaete-scute homolog (236 aa)
initn: 214 init1: 214 opt: 222 Z-score: 241.7 bits: 51.7 E(85289): 1e-06
Smith-Waterman score: 222; 43.3% identity (63.9% similar) in 97 aa overlap (82-175:104-200)
60 70 80 90 100
pF1KB9 ELPRLPFPSDSLILGNYSEPCPFSFPMPYPNYRGCEYSYG---PAFTRKRNERERQRVKC
:. : :: :: . .::::::.:::
NP_004 PSGGGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKL
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB9 VNEGYAQLRHHLPEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIA
:: :.: ::.:.:. .:..:::::::.:..:: ::.:: : . . : :
NP_004 VNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTI
140 150 160 170 180 190
170 180
pF1KB9 TTSHHADPMFRIV
. .. :
NP_004 SPNYSNDLNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF
200 210 220 230
>>NP_005161 (OMIM: 601886) achaete-scute homolog 2 [Homo (193 aa)
initn: 212 init1: 198 opt: 213 Z-score: 233.7 bits: 49.9 E(85289): 2.8e-06
Smith-Waterman score: 213; 42.6% identity (61.4% similar) in 101 aa overlap (53-149:6-106)
30 40 50 60 70 80
pF1KB9 LPLTRSFYLEPMVTFHVHPEAPVSSPYSEELPRLPFPSDSLILGNYSEPCPFSFPMPYPN
::: :. . .: .. : : . .
NP_005 MDGGTLPRSAPPAPPVPVGCAARRRPASPELLRCS
10 20 30
90 100 110 120 130
pF1KB9 YR----GCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHHLPEEYLEKRLSKVETLRAA
: : . : : . .::::::.::: :: :. ::.:.:. :.::::::::.:
NP_005 RRRRPATAETGGGAAAVARRNERERNRVKLVNLGFQALRQHVPHGGASKKLSKVETLRSA
40 50 60 70 80 90
140 150 160 170 180
pF1KB9 IKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRIV
..:: :: ::
NP_005 VEYIRALQRLLAEHDAVRNALAGGLRPQAVRPSAPRGPPGTTPVAASPSRASSSPGRGGS
100 110 120 130 140 150
>>NP_835455 (OMIM: 607194,609069,615935) pancreas transc (328 aa)
initn: 195 init1: 174 opt: 178 Z-score: 194.2 bits: 43.4 E(85289): 0.00045
Smith-Waterman score: 178; 51.9% identity (74.1% similar) in 54 aa overlap (99-152:169-222)
70 80 90 100 110 120
pF1KB9 SEPCPFSFPMPYPNYRGCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHHLPEEYLEKR
: :::.:.. .:... :: :.: :::
NP_835 RGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKR
140 150 160 170 180 190
130 140 150 160 170 180
pF1KB9 LSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRIV
::::.::: :: :::.:. :. :
NP_835 LSKVDTLRLAIGYINFLSELVQADLPLRGGGAGGCGGPGGGGRLGGDSPGSQAQKVIICH
200 210 220 230 240 250
>>NP_001277335 (OMIM: 187040,613065) T-cell acute lympho (172 aa)
initn: 169 init1: 155 opt: 161 Z-score: 180.6 bits: 39.9 E(85289): 0.0025
Smith-Waterman score: 161; 41.0% identity (61.4% similar) in 83 aa overlap (77-155:12-90)
50 60 70 80 90 100
pF1KB9 SPYSEELPRLPFPSDSLILGNYSEPCPFSFPMPYPNYRGCEYSYGP--AFTRK--RNERE
: :: : . :: .:. : ::
NP_001 MFTTNNRVKRRPSPYE----MEITDGPHTKVVRRIFTNSRE
10 20 30
110 120 130 140 150 160
pF1KB9 RQRVKCVNEGYAQLRHHLPEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGK
: : . :: ..:.::. .: . .:.::: : :: :.::::.: .:: .. :
NP_001 RWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKT
40 50 60 70 80 90
170 180
pF1KB9 VSSMIATTSHHADPMFRIV
NP_001 GKDPVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARS
100 110 120 130 140 150
>>XP_016857682 (OMIM: 187040,613065) PREDICTED: T-cell a (172 aa)
initn: 169 init1: 155 opt: 161 Z-score: 180.6 bits: 39.9 E(85289): 0.0025
Smith-Waterman score: 161; 41.0% identity (61.4% similar) in 83 aa overlap (77-155:12-90)
50 60 70 80 90 100
pF1KB9 SPYSEELPRLPFPSDSLILGNYSEPCPFSFPMPYPNYRGCEYSYGP--AFTRK--RNERE
: :: : . :: .:. : ::
XP_016 MFTTNNRVKRRPSPYE----MEITDGPHTKVVRRIFTNSRE
10 20 30
110 120 130 140 150 160
pF1KB9 RQRVKCVNEGYAQLRHHLPEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGK
: : . :: ..:.::. .: . .:.::: : :: :.::::.: .:: .. :
XP_016 RWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQEEEGTQRAKT
40 50 60 70 80 90
170 180
pF1KB9 VSSMIATTSHHADPMFRIV
XP_016 GKDPVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSYTEEPAPKHTARS
100 110 120 130 140 150
>>XP_005259969 (OMIM: 151440) PREDICTED: protein lyl-1 i (206 aa)
initn: 177 init1: 145 opt: 161 Z-score: 179.5 bits: 40.0 E(85289): 0.0029
Smith-Waterman score: 169; 31.8% identity (55.0% similar) in 129 aa overlap (33-160:24-143)
10 20 30 40 50 60
pF1KB9 DNRGNSSLPDKLPIFPDSARLPLTRSFYLEPMVTFHVHPEAPVSSPY-SEELPRLPFPSD
: ...: ::. ..: : . : :::.
XP_005 MPTTELGTLRPPLLQLSTLGTAPPTLALHYHPHPFLNSVYIGPAGPFSIFPSS
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 SLILGNYSEPCPFSFPMPYPNYRGCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHHLP
: : ... . . . .:: : ::: : . :: ..:.::. ::
XP_005 RL--KRRPSHCELDLAEGHQPQKVARR----VFT---NSRERWRQQNVNGAFAELRKLLP
60 70 80 90 100
130 140 150 160 170 180
pF1KB9 EEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRIV
. ...::: :.:: :.:::..: :: . : .:
XP_005 THPPDRKLSKNEVLRLAMKYIGFLVRLLRDQAAALAAGPTPPGPRKRPVHRVPDDGARRG
110 120 130 140 150 160
XP_005 SGRRAEAAARSQPAPPADPDGSPGGAARPIKMEQTALSPEVR
170 180 190 200
>>NP_005574 (OMIM: 151440) protein lyl-1 [Homo sapiens] (280 aa)
initn: 206 init1: 145 opt: 161 Z-score: 177.6 bits: 40.1 E(85289): 0.0037
Smith-Waterman score: 184; 32.0% identity (53.9% similar) in 178 aa overlap (4-160:47-217)
10 20
pF1KB9 MMDNRGNSS---LPDKLPIF------PDSARLP
.::.:: :: .:.. : .. .:
NP_005 KAEMVCAPSPAPAPPPKPASPGPPQVEEVGHRGGSSPPRLPPGVPVISLGHSRPPGVAMP
20 30 40 50 60 70
30 40 50 60 70 80
pF1KB9 LTRSFYLEP-MVTFHVHPEAPVSSPYSEELPRLPFPS-DSLILGNYSEPCPFS-FPMPYP
:. :.: .. . . :: : . : : : .:. .: . ::: ::
NP_005 TTELGTLRPPLLQLSTLGTAP---P-TLALHYHPHPFLNSVYIGPAG---PFSIFPSSRL
80 90 100 110 120
90 100 110 120 130
pF1KB9 NYRG--CEYS----YGPAFTRKR---NERERQRVKCVNEGYAQLRHHLPEEYLEKRLSKV
. : :: . . : . .: : ::: : . :: ..:.::. :: . ...:::
NP_005 KRRPSHCELDLAEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKN
130 140 150 160 170 180
140 150 160 170 180
pF1KB9 ETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRIV
:.:: :.:::..: :: . : .:
NP_005 EVLRLAMKYIGFLVRLLRDQAAALAAGPTPPGPRKRPVHRVPDDGARRGSGRRAEAAARS
190 200 210 220 230 240
>>NP_068808 (OMIM: 602407) heart- and neural crest deriv (217 aa)
initn: 140 init1: 140 opt: 159 Z-score: 177.1 bits: 39.6 E(85289): 0.004
Smith-Waterman score: 169; 29.5% identity (56.6% similar) in 122 aa overlap (40-152:37-158)
10 20 30 40 50 60
pF1KB9 LPDKLPIFPDSARLPLTRSFYLEPMVTFHVHPEAPVSSPYSEELPRLPFPSDSLILGNYS
: : : . :.. :. :. :.
NP_068 FPHHPVVHHEGYPFAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSMALSYSP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 EPCPFSFPMPYPNYRGCEYSYGPAF------TRKR---NERERQRVKCVNEGYAQLRHHL
: . . . .: : . :: ...: :..::.:.. .: ..:.::. .
NP_068 EYASGAAGLDHSHYGGVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 PEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRI
:. . .:::..::: : .:: ::..:: :
NP_068 PNVPADTKLSKIKTLRLATSYIAYLMDLLAKDDQNGEAEAFKAEIKKTDVKEEKRKKELN
130 140 150 160 170 180
pF1KB9 V
NP_068 EILKSTVSSNDKKTKGRTGWPQHVWALELKQ
190 200 210
181 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 17:28:38 2016 done: Fri Nov 4 17:28:38 2016
Total Scan time: 5.360 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]