Result of FASTA (omim) for
pFN21AB8969
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8969, 359 aa
1>>>pF1KB8969 359 - 359 aa - 359 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5491+/-0.000524; mu= 20.9069+/- 0.032
mean_var=88.4412+/-21.289, 0's: 0 Z-trim(107.3): 254 B-trim: 0 in 0/49
Lambda= 0.136379
statistics sampled from 15048 (15362) to 15048 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.525), E-opt: 0.2 (0.18), width: 16
Scan time: 7.280
The best scores are: opt bits E(85289)
NP_000950 (OMIM: 600563) prostaglandin F2-alpha re ( 359) 2355 474.3 1.9e-133
NP_001034674 (OMIM: 600563) prostaglandin F2-alpha ( 297) 1758 356.7 3.8e-98
XP_016857362 (OMIM: 600563) PREDICTED: prostagland ( 291) 1756 356.3 5e-98
XP_011526516 (OMIM: 188070,614009) PREDICTED: thro ( 343) 652 139.2 1.3e-32
NP_001051 (OMIM: 188070,614009) thromboxane A2 rec ( 343) 652 139.2 1.3e-32
NP_963998 (OMIM: 188070,614009) thromboxane A2 rec ( 407) 652 139.3 1.5e-32
NP_000946 (OMIM: 176802) prostaglandin E2 receptor ( 402) 528 114.8 3.3e-25
NP_942010 (OMIM: 176806) prostaglandin E2 receptor ( 365) 457 100.8 5e-21
NP_942009 (OMIM: 176806) prostaglandin E2 receptor ( 374) 457 100.8 5e-21
NP_942008 (OMIM: 176806) prostaglandin E2 receptor ( 388) 457 100.9 5.2e-21
NP_001119516 (OMIM: 176806) prostaglandin E2 recep ( 390) 457 100.9 5.2e-21
NP_942007 (OMIM: 176806) prostaglandin E2 receptor ( 390) 457 100.9 5.2e-21
NP_942012 (OMIM: 176806) prostaglandin E2 receptor ( 390) 457 100.9 5.2e-21
XP_011540112 (OMIM: 176806) PREDICTED: prostagland ( 410) 457 100.9 5.3e-21
NP_942011 (OMIM: 176806) prostaglandin E2 receptor ( 418) 457 100.9 5.4e-21
NP_000951 (OMIM: 600022) prostacyclin receptor [Ho ( 386) 406 90.8 5.4e-18
XP_005259152 (OMIM: 600022) PREDICTED: prostacycli ( 257) 293 68.4 2.1e-11
XP_005259150 (OMIM: 600022) PREDICTED: prostacycli ( 342) 293 68.5 2.5e-11
NP_000947 (OMIM: 176804,208550) prostaglandin E2 r ( 358) 260 62.1 2.3e-09
XP_016865146 (OMIM: 601586) PREDICTED: prostagland ( 326) 247 59.4 1.3e-08
XP_016865148 (OMIM: 601586) PREDICTED: prostagland ( 313) 243 58.6 2.1e-08
XP_016865147 (OMIM: 601586) PREDICTED: prostagland ( 325) 243 58.7 2.2e-08
XP_016865145 (OMIM: 601586) PREDICTED: prostagland ( 350) 243 58.7 2.3e-08
NP_000949 (OMIM: 601586) prostaglandin E2 receptor ( 488) 243 58.9 2.8e-08
NP_001268398 (OMIM: 604687,607277) prostaglandin D ( 296) 229 55.9 1.4e-07
XP_005267948 (OMIM: 604687,607277) PREDICTED: pros ( 359) 229 56.0 1.6e-07
NP_000944 (OMIM: 604687,607277) prostaglandin D2 r ( 359) 229 56.0 1.6e-07
NP_055137 (OMIM: 606695) opsin-3 [Homo sapiens] ( 402) 222 54.6 4.4e-07
NP_000943 (OMIM: 173393) platelet-activating facto ( 342) 211 52.4 1.8e-06
NP_001158195 (OMIM: 173393) platelet-activating fa ( 342) 211 52.4 1.8e-06
NP_001158193 (OMIM: 173393) platelet-activating fa ( 342) 211 52.4 1.8e-06
NP_001158194 (OMIM: 173393) platelet-activating fa ( 342) 211 52.4 1.8e-06
NP_000530 (OMIM: 136880,180380,610445,613731) rhod ( 348) 209 52.0 2.4e-06
XP_016864712 (OMIM: 600933) PREDICTED: proteinase- ( 383) 207 51.7 3.3e-06
NP_005233 (OMIM: 600933) proteinase-activated rece ( 397) 207 51.7 3.4e-06
NP_001243495 (OMIM: 601919) proteinase-activated r ( 352) 204 51.0 4.7e-06
NP_004092 (OMIM: 601919) proteinase-activated rece ( 374) 204 51.1 4.9e-06
NP_001049 (OMIM: 162323) substance-P receptor isof ( 407) 203 50.9 5.9e-06
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 201 50.5 7.6e-06
NP_064445 (OMIM: 300822,303700,303900) long-wave-s ( 364) 200 50.3 8.3e-06
NP_000397 (OMIM: 138850,146110) gonadotropin-relea ( 328) 196 49.4 1.3e-05
NP_001184113 (OMIM: 610118) probable G-protein cou ( 333) 195 49.2 1.5e-05
NP_006630 (OMIM: 300201) cysteinyl leukotriene rec ( 337) 194 49.0 1.8e-05
NP_001269116 (OMIM: 300201) cysteinyl leukotriene ( 337) 194 49.0 1.8e-05
NP_001269117 (OMIM: 300201) cysteinyl leukotriene ( 337) 194 49.0 1.8e-05
NP_001269115 (OMIM: 300201) cysteinyl leukotriene ( 337) 194 49.0 1.8e-05
NP_001699 (OMIM: 190900,613522) short-wave-sensiti ( 348) 194 49.1 1.8e-05
XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 190 48.3 3.2e-05
XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 190 48.3 3.2e-05
XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 190 48.3 3.2e-05
>>NP_000950 (OMIM: 600563) prostaglandin F2-alpha recept (359 aa)
initn: 2355 init1: 2355 opt: 2355 Z-score: 2516.8 bits: 474.3 E(85289): 1.9e-133
Smith-Waterman score: 2355; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359)
10 20 30 40 50 60
pF1KB8 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 RSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILD
250 260 270 280 290 300
310 320 330 340 350
pF1KB8 PWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
310 320 330 340 350
>>NP_001034674 (OMIM: 600563) prostaglandin F2-alpha rec (297 aa)
initn: 1755 init1: 1755 opt: 1758 Z-score: 1882.9 bits: 356.7 E(85289): 3.8e-98
Smith-Waterman score: 1758; 92.2% identity (94.6% similar) in 295 aa overlap (1-295:1-293)
10 20 30 40 50 60
pF1KB8 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 RSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILD
:::::::::::::::::::::::::: : .::... .. : :. :
NP_001 RSHHLEMVIQLLAIMCVSCICWSPFL--GYRIILNGKEKYKVYEEQSDFLHRLQWPTLE
250 260 270 280 290
310 320 330 340 350
pF1KB8 PWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
>>XP_016857362 (OMIM: 600563) PREDICTED: prostaglandin F (291 aa)
initn: 1755 init1: 1755 opt: 1756 Z-score: 1880.9 bits: 356.3 E(85289): 5e-98
Smith-Waterman score: 1756; 95.1% identity (97.2% similar) in 284 aa overlap (1-284:1-282)
10 20 30 40 50 60
pF1KB8 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 RSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILD
:::::::::::::::::::::::::: : .::... .. :
XP_016 RSHHLEMVIQLLAIMCVSCICWSPFL--GYRIILNGKEKYKVYEEQSDFLHRK
250 260 270 280 290
310 320 330 340 350
pF1KB8 PWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
>>XP_011526516 (OMIM: 188070,614009) PREDICTED: thrombox (343 aa)
initn: 645 init1: 311 opt: 652 Z-score: 706.2 bits: 139.2 E(85289): 1.3e-32
Smith-Waterman score: 652; 40.2% identity (66.2% similar) in 311 aa overlap (18-315:15-319)
10 20 30 40 50
pF1KB8 MSMNNSKQLVSPAAALLSNTTCQTENRL--SVFFSVIFMTVGILSNSLAIAILMKAYQRF
.: : . : :: : .:.. : .::. :: ::...: : :
XP_011 MWPNGSSLGPCFRPTNITLE-ERRLIASPWFAASFCVVGLASNLLALSVLAGARQG-
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 RQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFS
.....::: . :::.:::.: :..:.:.: .:. :: : . :: ..:. :.:
XP_011 GSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 GLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVF-IALLPILGHRDY
:: :::::..:: :: .:.:.: : ..:.. :. :.. ..:::.:: :
XP_011 GLSPLLLGAAMASERYLGITRP-FSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 KIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQH
.: .::: . . : . ::::.:: :..:.:.: :... :: .: ...:.
XP_011 TVQYPGSWCFLTLG--AESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHV-YHGQEA
180 190 200 210 220 230
240 250 260 270 280
pF1KB8 RQGRSH--HLEMVIQLLAIMCVSCICWSPFLVTMAN--------IGINGNHSLETCETTL
: : . ..::. :::.:: :. .:: :.:: .:. .. :. : : . :
XP_011 AQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB8 FALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAI
. ::.::::::::::::::.:.:::. :
XP_011 IYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
300 310 320 330 340
>>NP_001051 (OMIM: 188070,614009) thromboxane A2 recepto (343 aa)
initn: 645 init1: 311 opt: 652 Z-score: 706.2 bits: 139.2 E(85289): 1.3e-32
Smith-Waterman score: 652; 40.2% identity (66.2% similar) in 311 aa overlap (18-315:15-319)
10 20 30 40 50
pF1KB8 MSMNNSKQLVSPAAALLSNTTCQTENRL--SVFFSVIFMTVGILSNSLAIAILMKAYQRF
.: : . : :: : .:.. : .::. :: ::...: : :
NP_001 MWPNGSSLGPCFRPTNITLE-ERRLIASPWFAASFCVVGLASNLLALSVLAGARQG-
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 RQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFS
.....::: . :::.:::.: :..:.:.: .:. :: : . :: ..:. :.:
NP_001 GSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 GLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVF-IALLPILGHRDY
:: :::::..:: :: .:.:.: : ..:.. :. :.. ..:::.:: :
NP_001 GLSPLLLGAAMASERYLGITRP-FSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 KIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQH
.: .::: . . : . ::::.:: :..:.:.: :... :: .: ...:.
NP_001 TVQYPGSWCFLTLG--AESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHV-YHGQEA
180 190 200 210 220 230
240 250 260 270 280
pF1KB8 RQGRSH--HLEMVIQLLAIMCVSCICWSPFLVTMAN--------IGINGNHSLETCETTL
: : . ..::. :::.:: :. .:: :.:: .:. .. :. : : . :
NP_001 AQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB8 FALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAI
. ::.::::::::::::::.:.:::. :
NP_001 IYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
300 310 320 330 340
>>NP_963998 (OMIM: 188070,614009) thromboxane A2 recepto (407 aa)
initn: 655 init1: 311 opt: 652 Z-score: 705.4 bits: 139.3 E(85289): 1.5e-32
Smith-Waterman score: 652; 40.2% identity (66.2% similar) in 311 aa overlap (18-315:15-319)
10 20 30 40 50
pF1KB8 MSMNNSKQLVSPAAALLSNTTCQTENRL--SVFFSVIFMTVGILSNSLAIAILMKAYQRF
.: : . : :: : .:.. : .::. :: ::...: : :
NP_963 MWPNGSSLGPCFRPTNITLE-ERRLIASPWFAASFCVVGLASNLLALSVLAGARQG-
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 RQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFS
.....::: . :::.:::.: :..:.:.: .:. :: : . :: ..:. :.:
NP_963 GSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 GLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVF-IALLPILGHRDY
:: :::::..:: :: .:.:.: : ..:.. :. :.. ..:::.:: :
NP_963 GLSPLLLGAAMASERYLGITRP-FSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 KIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQH
.: .::: . . : . ::::.:: :..:.:.: :... :: .: ...:.
NP_963 TVQYPGSWCFLTLG--AESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHV-YHGQEA
180 190 200 210 220 230
240 250 260 270 280
pF1KB8 RQGRSH--HLEMVIQLLAIMCVSCICWSPFLVTMAN--------IGINGNHSLETCETTL
: : . ..::. :::.:: :. .:: :.:: .:. .. :. : : . :
NP_963 AQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB8 FALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAI
. ::.::::::::::::::.:.:::. :
NP_963 IYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRRSLTLWPSLEYSGTISAHCNLRL
300 310 320 330 340 350
>>NP_000946 (OMIM: 176802) prostaglandin E2 receptor EP1 (402 aa)
initn: 785 init1: 369 opt: 528 Z-score: 573.6 bits: 114.8 E(85289): 3.3e-25
Smith-Waterman score: 734; 34.1% identity (62.1% similar) in 393 aa overlap (1-340:7-393)
10 20 30 40 50
pF1KB8 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKA
.... . . .. :: . ::. . : . .. ::.: .:: ::.:.: .:
NP_000 MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 YQRFRQK-SKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGI
:.:.. : :.:::....:. ::. ::.: ::... .:.. . .. : ..:
NP_000 AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----PAGGACHFLGG
70 80 90 100 110
120 130 140 150 160 170
pF1KB8 CMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILG
:::: :::::::: ::.:::.:::.:..:..... .... :..: :. .::::.
NP_000 CMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLAR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 HRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFK
:..: :::: . :.. . ::. :::.:: ..:.::...:..:::....
NP_000 VGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWR
180 190 200 210 220 230
240
pF1KB8 ----------------------------------------------SQQHRQGRSHHLEM
: . :..:.: .::
NP_000 RRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEM
240 250 260 270 280 290
250 260 270 280 290 300
pF1KB8 VIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILL
: ::..:: ::::::::.:: .: ....: : . ..:.:.:.:::::::::::::
NP_000 VGQLVGIMVVSCICWSPMLVLVA-LAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILL
300 310 320 330 340 350
310 320 330 340 350
pF1KB8 RKAVLKNLYKLASQCCGVHV------ISLHIWELSSIKNSLKVAAISESPVAEKSAST
:.:::..: .: :.. .. :: ::...
NP_000 RQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
360 370 380 390 400
>>NP_942010 (OMIM: 176806) prostaglandin E2 receptor EP3 (365 aa)
initn: 633 init1: 386 opt: 457 Z-score: 498.5 bits: 100.8 E(85289): 5e-21
Smith-Waterman score: 666; 36.9% identity (67.6% similar) in 309 aa overlap (28-315:50-357)
10 20 30 40 50
pF1KB8 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQR
.:: : . .. .:...:.::. .. ..:.:
NP_942 SYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRR
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB8 FRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVF
..: : :::: . :..::. :.:.. ... :: : ..: ..: :. ::..::. :.
NP_942 RESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTV
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB8 SGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDY
:: :...:.::.:: ... : ...... .. .. .: :: : .. .::::.:: .:
NP_942 FGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQY
140 150 160 170 180 190
180 190 200 210 220
pF1KB8 KIQASRTWCFYNT-------EDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLL-R
.: :::: .: . ..: . :. :.::::::: :.. :: : .:. :
NP_942 TVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSR
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB8 VKFK---SQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETT
. : ::. : : .:::..:::: .::::.:. : .. .: . :.: :.:
NP_942 CRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFN-QTSVEHCKTH
260 270 280 290 300 310
290 300 310 320 330
pF1KB8 ----------LFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELS
:.:.:.:. :::::::::.:::: .:...
NP_942 TEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQEEFWGN
320 330 340 350 360
340 350
pF1KB8 SIKNSLKVAAISESPVAEKSAST
>>NP_942009 (OMIM: 176806) prostaglandin E2 receptor EP3 (374 aa)
initn: 635 init1: 386 opt: 457 Z-score: 498.4 bits: 100.8 E(85289): 5e-21
Smith-Waterman score: 668; 36.5% identity (67.6% similar) in 312 aa overlap (28-318:50-360)
10 20 30 40 50
pF1KB8 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQR
.:: : . .. .:...:.::. .. ..:.:
NP_942 SYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRR
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB8 FRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVF
..: : :::: . :..::. :.:.. ... :: : ..: ..: :. ::..::. :.
NP_942 RESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTV
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB8 SGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDY
:: :...:.::.:: ... : ...... .. .. .: :: : .. .::::.:: .:
NP_942 FGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQY
140 150 160 170 180 190
180 190 200 210 220
pF1KB8 KIQASRTWCFYNT-------EDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLL-R
.: :::: .: . ..: . :. :.::::::: :.. :: : .:. :
NP_942 TVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSR
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB8 VKFK---SQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETT
. : ::. : : .:::..:::: .::::.:. : .. .: . :.: :.:
NP_942 CRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFN-QTSVEHCKTH
260 270 280 290 300 310
290 300 310 320 330
pF1KB8 ----------LFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELS
:.:.:.:. :::::::::.:::: .:... ..
NP_942 TEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQMRKRRLREQEEFWGN
320 330 340 350 360 370
340 350
pF1KB8 SIKNSLKVAAISESPVAEKSAST
>>NP_942008 (OMIM: 176806) prostaglandin E2 receptor EP3 (388 aa)
initn: 639 init1: 386 opt: 457 Z-score: 498.2 bits: 100.9 E(85289): 5.2e-21
Smith-Waterman score: 673; 36.7% identity (67.4% similar) in 319 aa overlap (28-322:50-367)
10 20 30 40 50
pF1KB8 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQR
.:: : . .. .:...:.::. .. ..:.:
NP_942 SYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRR
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB8 FRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVF
..: : :::: . :..::. :.:.. ... :: : ..: ..: :. ::..::. :.
NP_942 RESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTV
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB8 SGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDY
:: :...:.::.:: ... : ...... .. .. .: :: : .. .::::.:: .:
NP_942 FGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQY
140 150 160 170 180 190
180 190 200 210 220
pF1KB8 KIQASRTWCFYNT-------EDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLL-R
.: :::: .: . ..: . :. :.::::::: :.. :: : .:. :
NP_942 TVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSR
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB8 VKFK---SQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETT
. : ::. : : .:::..:::: .::::.:. : .. .: . :.: :.:
NP_942 CRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQT-SVEHCKTH
260 270 280 290 300 310
290 300 310 320 330
pF1KB8 ----------LFALRMATWNQILDPWVYILLRKAVLKNLYKLA---SQCCGVHVISLHIW
:.:.:.:. :::::::::.:::: .:... ..: :.:
NP_942 TEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQVANAVSSCSNDGQKGQPIS
320 330 340 350 360 370
340 350
pF1KB8 ELSSIKNSLKVAAISESPVAEKSAST
NP_942 LSNEIIQTEA
380
359 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:44:49 2016 done: Fri Nov 4 16:44:51 2016
Total Scan time: 7.280 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]