Result of FASTA (omim) for
pFN21AB8955
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8955, 332 aa
1>>>pF1KB8955 332 - 332 aa - 332 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3550+/-0.000469; mu= 15.2893+/- 0.029
mean_var=99.9815+/-26.001, 0's: 0 Z-trim(109.1): 540 B-trim: 1961 in 2/52
Lambda= 0.128267
statistics sampled from 16457 (17239) to 16457 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.547), E-opt: 0.2 (0.202), width: 16
Scan time: 7.280
The best scores are: opt bits E(85289)
NP_000667 (OMIM: 600446) adenosine receptor A2b [H ( 332) 2200 418.4 1e-116
XP_011521961 (OMIM: 600446) PREDICTED: adenosine r ( 229) 1514 291.3 1.3e-78
XP_016879686 (OMIM: 600446) PREDICTED: adenosine r ( 231) 1502 289.1 6.2e-78
NP_001265427 (OMIM: 102776) adenosine receptor A2a ( 412) 1274 247.2 4.6e-65
NP_000666 (OMIM: 102776) adenosine receptor A2a [H ( 412) 1274 247.2 4.6e-65
NP_001265428 (OMIM: 102776) adenosine receptor A2a ( 412) 1274 247.2 4.6e-65
NP_001265426 (OMIM: 102776) adenosine receptor A2a ( 412) 1274 247.2 4.6e-65
NP_001265429 (OMIM: 102776) adenosine receptor A2a ( 412) 1274 247.2 4.6e-65
NP_000665 (OMIM: 102775) adenosine receptor A1 [Ho ( 326) 903 178.4 1.8e-44
NP_001041695 (OMIM: 102775) adenosine receptor A1 ( 326) 903 178.4 1.8e-44
XP_011521963 (OMIM: 600446) PREDICTED: adenosine r ( 116) 698 140.0 2.4e-33
XP_005244958 (OMIM: 102775) PREDICTED: adenosine r ( 258) 562 115.2 1.5e-25
XP_016855831 (OMIM: 102775) PREDICTED: adenosine r ( 258) 562 115.2 1.5e-25
XP_005244959 (OMIM: 102775) PREDICTED: adenosine r ( 258) 562 115.2 1.5e-25
NP_000668 (OMIM: 600445) adenosine receptor A3 iso ( 318) 462 96.8 6.6e-20
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 356 77.3 6.5e-14
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415) 354 76.9 8.2e-14
NP_612200 (OMIM: 609333) trace amine-associated re ( 339) 352 76.5 9.3e-14
NP_001289608 (OMIM: 600445) adenosine receptor A3 ( 173) 348 75.4 9.8e-14
NP_001289607 (OMIM: 600445) adenosine receptor A3 ( 123) 342 74.1 1.7e-13
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 333 73.1 1.3e-12
NP_778227 (OMIM: 608282) trace amine-associated re ( 348) 325 71.5 3e-12
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 324 71.4 4e-12
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359) 323 71.1 4e-12
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362) 323 71.1 4e-12
NP_001124527 (OMIM: 142703) histamine H2 receptor ( 397) 323 71.2 4.3e-12
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422) 323 71.2 4.4e-12
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422) 323 71.2 4.4e-12
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422) 323 71.2 4.4e-12
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422) 323 71.2 4.4e-12
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422) 323 71.2 4.4e-12
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 321 70.8 5.9e-12
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 321 70.9 6.1e-12
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 319 70.5 8.1e-12
NP_778237 (OMIM: 608923) trace amine-associated re ( 345) 317 70.0 8.4e-12
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 319 70.5 8.7e-12
XP_011508789 (OMIM: 604153) PREDICTED: neuromedin- ( 403) 316 69.9 1.1e-11
NP_006047 (OMIM: 604153) neuromedin-U receptor 1 [ ( 426) 316 69.9 1.1e-11
NP_149421 (OMIM: 114610) cannabinoid receptor 1 is ( 439) 314 69.5 1.4e-11
XP_016865728 (OMIM: 114610) PREDICTED: cannabinoid ( 472) 314 69.6 1.5e-11
NP_057167 (OMIM: 114610) cannabinoid receptor 1 is ( 472) 314 69.6 1.5e-11
NP_001153731 (OMIM: 114610) cannabinoid receptor 1 ( 472) 314 69.6 1.5e-11
XP_011533726 (OMIM: 114610) PREDICTED: cannabinoid ( 472) 314 69.6 1.5e-11
XP_011533730 (OMIM: 114610) PREDICTED: cannabinoid ( 472) 314 69.6 1.5e-11
NP_001153730 (OMIM: 114610) cannabinoid receptor 1 ( 472) 314 69.6 1.5e-11
NP_001153698 (OMIM: 114610) cannabinoid receptor 1 ( 472) 314 69.6 1.5e-11
XP_011533728 (OMIM: 114610) PREDICTED: cannabinoid ( 472) 314 69.6 1.5e-11
XP_006715393 (OMIM: 114610) PREDICTED: cannabinoid ( 472) 314 69.6 1.5e-11
XP_016865729 (OMIM: 114610) PREDICTED: cannabinoid ( 472) 314 69.6 1.5e-11
XP_016865727 (OMIM: 114610) PREDICTED: cannabinoid ( 472) 314 69.6 1.5e-11
>>NP_000667 (OMIM: 600446) adenosine receptor A2b [Homo (332 aa)
initn: 2200 init1: 2200 opt: 2200 Z-score: 2216.3 bits: 418.4 E(85289): 1e-116
Smith-Waterman score: 2200; 100.0% identity (100.0% similar) in 332 aa overlap (1-332:1-332)
10 20 30 40 50 60
pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
250 260 270 280 290 300
310 320 330
pF1KB8 FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
::::::::::::::::::::::::::::::::
NP_000 FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
310 320 330
>>XP_011521961 (OMIM: 600446) PREDICTED: adenosine recep (229 aa)
initn: 1514 init1: 1514 opt: 1514 Z-score: 1532.2 bits: 291.3 E(85289): 1.3e-78
Smith-Waterman score: 1514; 100.0% identity (100.0% similar) in 222 aa overlap (111-332:8-229)
90 100 110 120 130 140
pF1KB8 LACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTP
::::::::::::::::::::::::::::::
XP_011 MSERSRTLRYKSLVTGTRARGVIAVLWVLAFGIGLTP
10 20 30
150 160 170 180 190 200
pF1KB8 FLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLV
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB8 IYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQ
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB8 PAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNG
160 170 180 190 200 210
330
pF1KB8 QAGVQPALGVGL
::::::::::::
XP_011 QAGVQPALGVGL
220
>>XP_016879686 (OMIM: 600446) PREDICTED: adenosine recep (231 aa)
initn: 1502 init1: 1502 opt: 1502 Z-score: 1520.2 bits: 289.1 E(85289): 6.2e-78
Smith-Waterman score: 1502; 100.0% identity (100.0% similar) in 220 aa overlap (113-332:12-231)
90 100 110 120 130 140
pF1KB8 CFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFL
::::::::::::::::::::::::::::::
XP_016 MKAAHVVLSAWYKSLVTGTRARGVIAVLWVLAFGIGLTPFL
10 20 30 40
150 160 170 180 190 200
pF1KB8 GWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIY
50 60 70 80 90 100
210 220 230 240 250 260
pF1KB8 IKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPA
110 120 130 140 150 160
270 280 290 300 310 320
pF1KB8 QGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQA
170 180 190 200 210 220
330
pF1KB8 GVQPALGVGL
::::::::::
XP_016 GVQPALGVGL
230
>>NP_001265427 (OMIM: 102776) adenosine receptor A2a [Ho (412 aa)
initn: 1234 init1: 824 opt: 1274 Z-score: 1289.0 bits: 247.2 E(85289): 4.6e-65
Smith-Waterman score: 1274; 59.4% identity (82.1% similar) in 330 aa overlap (8-329:7-328)
10 20 30 40 50 60
pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
..:...::.::.:.. :::::: :: ..::. ::::.:::::::.:::..:
NP_001 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLA
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
:::::::: :::. .::::.:::::::::::::::::.:.:::.:: .::::..:::::
NP_001 IPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGT
60 70 80 90 100 110
130 140 150 160 170
pF1KB8 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCC---LVKCLFENVV
::.:.::. :::.:.:::::.:::: :: .: .: .. . : : ::::.::
NP_001 RAKGIIAICWVLSFAIGLTPMLGWN-------NCGQPKEGKNHSQGCGEGQVACLFEDVV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 PMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELM----DHSRTTLQREIHAA
::.::::::::.::: :::.:: .:..:::.: :::.. : . ...:.:::.:.:::
NP_001 PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 KSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYR
::::.:::.:::::::.: .:: :.: : . .. : : : .::.:::.::::::..::::
NP_001 KSLAIIVGLFALCWLPLHIINCFTFFCP-DCSHAPLWLMYLAIVLSHTNSVVNPFIYAYR
240 250 260 270 280 290
300 310 320 330
pF1KB8 NRDFRYTFHKIISRYLLCQAD-VKSGNGQAGVQPALGVGL
:.:: ::.::: ..: : . :... .: : : :
NP_001 IREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSA
300 310 320 330 340 350
NP_001 PHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGV
360 370 380 390 400 410
>>NP_000666 (OMIM: 102776) adenosine receptor A2a [Homo (412 aa)
initn: 1234 init1: 824 opt: 1274 Z-score: 1289.0 bits: 247.2 E(85289): 4.6e-65
Smith-Waterman score: 1274; 59.4% identity (82.1% similar) in 330 aa overlap (8-329:7-328)
10 20 30 40 50 60
pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
..:...::.::.:.. :::::: :: ..::. ::::.:::::::.:::..:
NP_000 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLA
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
:::::::: :::. .::::.:::::::::::::::::.:.:::.:: .::::..:::::
NP_000 IPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGT
60 70 80 90 100 110
130 140 150 160 170
pF1KB8 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCC---LVKCLFENVV
::.:.::. :::.:.:::::.:::: :: .: .: .. . : : ::::.::
NP_000 RAKGIIAICWVLSFAIGLTPMLGWN-------NCGQPKEGKNHSQGCGEGQVACLFEDVV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 PMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELM----DHSRTTLQREIHAA
::.::::::::.::: :::.:: .:..:::.: :::.. : . ...:.:::.:.:::
NP_000 PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 KSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYR
::::.:::.:::::::.: .:: :.: : . .. : : : .::.:::.::::::..::::
NP_000 KSLAIIVGLFALCWLPLHIINCFTFFCP-DCSHAPLWLMYLAIVLSHTNSVVNPFIYAYR
240 250 260 270 280 290
300 310 320 330
pF1KB8 NRDFRYTFHKIISRYLLCQAD-VKSGNGQAGVQPALGVGL
:.:: ::.::: ..: : . :... .: : : :
NP_000 IREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSA
300 310 320 330 340 350
NP_000 PHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGV
360 370 380 390 400 410
>>NP_001265428 (OMIM: 102776) adenosine receptor A2a [Ho (412 aa)
initn: 1234 init1: 824 opt: 1274 Z-score: 1289.0 bits: 247.2 E(85289): 4.6e-65
Smith-Waterman score: 1274; 59.4% identity (82.1% similar) in 330 aa overlap (8-329:7-328)
10 20 30 40 50 60
pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
..:...::.::.:.. :::::: :: ..::. ::::.:::::::.:::..:
NP_001 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLA
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
:::::::: :::. .::::.:::::::::::::::::.:.:::.:: .::::..:::::
NP_001 IPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGT
60 70 80 90 100 110
130 140 150 160 170
pF1KB8 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCC---LVKCLFENVV
::.:.::. :::.:.:::::.:::: :: .: .: .. . : : ::::.::
NP_001 RAKGIIAICWVLSFAIGLTPMLGWN-------NCGQPKEGKNHSQGCGEGQVACLFEDVV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 PMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELM----DHSRTTLQREIHAA
::.::::::::.::: :::.:: .:..:::.: :::.. : . ...:.:::.:.:::
NP_001 PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 KSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYR
::::.:::.:::::::.: .:: :.: : . .. : : : .::.:::.::::::..::::
NP_001 KSLAIIVGLFALCWLPLHIINCFTFFCP-DCSHAPLWLMYLAIVLSHTNSVVNPFIYAYR
240 250 260 270 280 290
300 310 320 330
pF1KB8 NRDFRYTFHKIISRYLLCQAD-VKSGNGQAGVQPALGVGL
:.:: ::.::: ..: : . :... .: : : :
NP_001 IREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSA
300 310 320 330 340 350
NP_001 PHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGV
360 370 380 390 400 410
>>NP_001265426 (OMIM: 102776) adenosine receptor A2a [Ho (412 aa)
initn: 1234 init1: 824 opt: 1274 Z-score: 1289.0 bits: 247.2 E(85289): 4.6e-65
Smith-Waterman score: 1274; 59.4% identity (82.1% similar) in 330 aa overlap (8-329:7-328)
10 20 30 40 50 60
pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
..:...::.::.:.. :::::: :: ..::. ::::.:::::::.:::..:
NP_001 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLA
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
:::::::: :::. .::::.:::::::::::::::::.:.:::.:: .::::..:::::
NP_001 IPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGT
60 70 80 90 100 110
130 140 150 160 170
pF1KB8 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCC---LVKCLFENVV
::.:.::. :::.:.:::::.:::: :: .: .: .. . : : ::::.::
NP_001 RAKGIIAICWVLSFAIGLTPMLGWN-------NCGQPKEGKNHSQGCGEGQVACLFEDVV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 PMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELM----DHSRTTLQREIHAA
::.::::::::.::: :::.:: .:..:::.: :::.. : . ...:.:::.:.:::
NP_001 PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 KSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYR
::::.:::.:::::::.: .:: :.: : . .. : : : .::.:::.::::::..::::
NP_001 KSLAIIVGLFALCWLPLHIINCFTFFCP-DCSHAPLWLMYLAIVLSHTNSVVNPFIYAYR
240 250 260 270 280 290
300 310 320 330
pF1KB8 NRDFRYTFHKIISRYLLCQAD-VKSGNGQAGVQPALGVGL
:.:: ::.::: ..: : . :... .: : : :
NP_001 IREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSA
300 310 320 330 340 350
NP_001 PHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGV
360 370 380 390 400 410
>>NP_001265429 (OMIM: 102776) adenosine receptor A2a [Ho (412 aa)
initn: 1234 init1: 824 opt: 1274 Z-score: 1289.0 bits: 247.2 E(85289): 4.6e-65
Smith-Waterman score: 1274; 59.4% identity (82.1% similar) in 330 aa overlap (8-329:7-328)
10 20 30 40 50 60
pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
..:...::.::.:.. :::::: :: ..::. ::::.:::::::.:::..:
NP_001 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLA
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
:::::::: :::. .::::.:::::::::::::::::.:.:::.:: .::::..:::::
NP_001 IPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGT
60 70 80 90 100 110
130 140 150 160 170
pF1KB8 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCC---LVKCLFENVV
::.:.::. :::.:.:::::.:::: :: .: .: .. . : : ::::.::
NP_001 RAKGIIAICWVLSFAIGLTPMLGWN-------NCGQPKEGKNHSQGCGEGQVACLFEDVV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 PMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELM----DHSRTTLQREIHAA
::.::::::::.::: :::.:: .:..:::.: :::.. : . ...:.:::.:.:::
NP_001 PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 KSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYR
::::.:::.:::::::.: .:: :.: : . .. : : : .::.:::.::::::..::::
NP_001 KSLAIIVGLFALCWLPLHIINCFTFFCP-DCSHAPLWLMYLAIVLSHTNSVVNPFIYAYR
240 250 260 270 280 290
300 310 320 330
pF1KB8 NRDFRYTFHKIISRYLLCQAD-VKSGNGQAGVQPALGVGL
:.:: ::.::: ..: : . :... .: : : :
NP_001 IREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSA
300 310 320 330 340 350
NP_001 PHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGV
360 370 380 390 400 410
>>NP_000665 (OMIM: 102775) adenosine receptor A1 [Homo s (326 aa)
initn: 740 init1: 472 opt: 903 Z-score: 919.3 bits: 178.4 E(85289): 1.8e-44
Smith-Waterman score: 903; 48.5% identity (74.6% similar) in 307 aa overlap (8-312:10-310)
10 20 30 40 50
pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGL
: :...:..:: .:: ::::: :: . ..:. : :.::::.::::::
NP_000 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 FAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVT
..::.:: :..: : :. ::..:: ::.::::::..:::.:::::: . .::::: .::
NP_000 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 GTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVP
:: .:: :.:.: .::::..:::. ::.. . : .. . . ..:: ::.:.
NP_000 PRRAAVAIAGCWILSFVVGLTPMFGWNNL-SAVE---RAWAANGSMGEPVIKCEFEKVIS
130 140 150 160 170
180 190 200 210 220 230
pF1KB8 MSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQR--TELMDHSRTTLQREIHAAKSL
: :::::::: ::::::.:..::...: . .::.. . . .:.. ::::
NP_000 MEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 AMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRD
:.:. .::: :::.: .::.::: :. .::. .::.:.:.::..::::::.: .
NP_000 ALILFLFALSWLPLHILNCITLFCPSC--HKPSILTYIAIFLTHGNSAMNPIVYAFRIQK
240 250 260 270 280 290
300 310 320 330
pF1KB8 FRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
:: :: :: . .. ::
NP_000 FRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
300 310 320
>>NP_001041695 (OMIM: 102775) adenosine receptor A1 [Hom (326 aa)
initn: 740 init1: 472 opt: 903 Z-score: 919.3 bits: 178.4 E(85289): 1.8e-44
Smith-Waterman score: 903; 48.5% identity (74.6% similar) in 307 aa overlap (8-312:10-310)
10 20 30 40 50
pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGL
: :...:..:: .:: ::::: :: . ..:. : :.::::.::::::
NP_001 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 FAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVT
..::.:: :..: : :. ::..:: ::.::::::..:::.:::::: . .::::: .::
NP_001 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 GTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVP
:: .:: :.:.: .::::..:::. ::.. . : .. . . ..:: ::.:.
NP_001 PRRAAVAIAGCWILSFVVGLTPMFGWNNL-SAVE---RAWAANGSMGEPVIKCEFEKVIS
130 140 150 160 170
180 190 200 210 220 230
pF1KB8 MSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQR--TELMDHSRTTLQREIHAAKSL
: :::::::: ::::::.:..::...: . .::.. . . .:.. ::::
NP_001 MEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 AMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRD
:.:. .::: :::.: .::.::: :. .::. .::.:.:.::..::::::.: .
NP_001 ALILFLFALSWLPLHILNCITLFCPSC--HKPSILTYIAIFLTHGNSAMNPIVYAFRIQK
240 250 260 270 280 290
300 310 320 330
pF1KB8 FRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
:: :: :: . .. ::
NP_001 FRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
300 310 320
332 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:40:18 2016 done: Fri Nov 4 16:40:19 2016
Total Scan time: 7.280 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]