Result of FASTA (omim) for
pFN21AB8932
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8932, 283 aa
1>>>pF1KB8932 283 - 283 aa - 283 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.8534+/-0.000332; mu= -2.2816+/- 0.021
mean_var=317.4752+/-64.608, 0's: 0 Z-trim(126.0): 198 B-trim: 888 in 2/60
Lambda= 0.071981
statistics sampled from 50654 (50914) to 50654 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.85), E-opt: 0.2 (0.597), width: 16
Scan time: 8.220
The best scores are: opt bits E(85289)
NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 2029 223.0 5e-58
XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 463 60.6 6.1e-09
XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 463 60.6 6.1e-09
XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 463 60.6 6.1e-09
XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 463 60.6 6.1e-09
XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 463 60.6 6.1e-09
NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 463 60.6 6.1e-09
NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 463 60.6 6.1e-09
NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 394 53.3 7e-07
NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 393 53.2 8.1e-07
XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 393 53.3 9.3e-07
XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 393 53.3 9.3e-07
NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 393 53.3 9.3e-07
XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 393 53.3 9.3e-07
XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 393 53.3 9.3e-07
XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 393 53.3 9.3e-07
XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 393 53.3 9.3e-07
XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 393 53.3 9.3e-07
NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 387 52.5 9.7e-07
NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 380 51.7 1.6e-06
NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 377 51.4 2.1e-06
NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 377 51.4 2.1e-06
NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 367 50.5 4.7e-06
XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 370 50.9 4.9e-06
XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 367 50.5 5.3e-06
NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 367 50.5 5.3e-06
NP_002137 (OMIM: 142966) homeobox protein Hox-B3 i ( 431) 367 50.6 6e-06
XP_011523021 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 367 50.6 6e-06
XP_005257334 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 367 50.6 6e-06
XP_006721917 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 367 50.6 6e-06
XP_011523012 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 367 50.6 6e-06
XP_011523022 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 367 50.6 6e-06
XP_011523010 (OMIM: 142966) PREDICTED: homeobox pr ( 488) 367 50.7 6.6e-06
XP_016880051 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 367 50.7 7.4e-06
XP_011523009 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 367 50.7 7.4e-06
XP_016880052 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 367 50.7 7.4e-06
XP_016880047 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 367 50.7 7.4e-06
XP_016880049 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 367 50.7 7.4e-06
XP_016880046 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 367 50.7 7.4e-06
XP_016880050 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 367 50.7 7.4e-06
XP_016880048 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 367 50.7 7.4e-06
NP_663632 (OMIM: 616542) GS homeobox 1 [Homo sapie ( 264) 355 49.2 1e-05
NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 317 45.1 0.00014
XP_005257332 (OMIM: 142967) PREDICTED: homeobox pr ( 247) 317 45.2 0.00015
NP_062458 (OMIM: 142985) homeobox protein Hox-D8 i ( 290) 318 45.4 0.00015
NP_005506 (OMIM: 142994,176450) motor neuron and p ( 401) 320 45.7 0.00017
NP_001186675 (OMIM: 142985) homeobox protein Hox-D ( 289) 315 45.0 0.00019
NP_001795 (OMIM: 600746) homeobox protein CDX-1 [H ( 265) 312 44.7 0.00022
NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 311 44.6 0.00024
NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 309 44.3 0.00025
>>NP_000200 (OMIM: 125853,260370,600733,606176,606392) p (283 aa)
initn: 2029 init1: 2029 opt: 2029 Z-score: 1162.8 bits: 223.0 E(85289): 5e-58
Smith-Waterman score: 2029; 100.0% identity (100.0% similar) in 283 aa overlap (1-283:1-283)
10 20 30 40 50 60
pF1KB8 MNGEEQYYAATQLYKDPCAFQRGPAPEFSASPPACLYMGRQPPPPPPHPFPGALGALEQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MNGEEQYYAATQLYKDPCAFQRGPAPEFSASPPACLYMGRQPPPPPPHPFPGALGALEQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SPPDISPYEVPPLADDPAVAHLHHHLPAQLALPHPPAGPFPEGAEPGVLEEPNRVQLPFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SPPDISPYEVPPLADDPAVAHLHHHLPAQLALPHPPAGPFPEGAEPGVLEEPNRVQLPFP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 WMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 WMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLALPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLALPP
190 200 210 220 230 240
250 260 270 280
pF1KB8 PPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
:::::::::::::::::::::::::::::::::::::::::::
NP_000 PPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
250 260 270 280
>>XP_005249788 (OMIM: 142954) PREDICTED: homeobox protei (443 aa)
initn: 453 init1: 310 opt: 463 Z-score: 281.5 bits: 60.6 E(85289): 6.1e-09
Smith-Waterman score: 477; 35.4% identity (55.4% similar) in 316 aa overlap (2-281:27-327)
10 20
pF1KB8 MNGEEQYYAAT-------QLYKDPCAFQR----GP
:...: : :. . .. :..: :
XP_005 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG
10 20 30 40 50 60
30 40 50 60 70
pF1KB8 APEFSASPPACLYMGRQPP--PP----PP-HPFPGALGALEQGSPPDISPYEVPPLADDP
:. ::: :: :: :: :: : .: .::. .: :: : :
XP_005 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHP-PPPQAAPPAPQPPQPAPQ--PP-APTP
70 80 90 100 110
80 90 100 110 120 130
pF1KB8 AVAHLHHHLPAQLALPHPPAG--PFP-EGAEPGVLEEPNRVQLPFPWMKSTKAHAWK---
:. : . : : :. : : ..:. .:. :. .. ::::: .. .. .
XP_005 AAPP-----PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTS
120 130 140 150 160 170
140 150 160 170 180
pF1KB8 ----GQWAGGAYAAEPEEN-KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLT
:. .: . . . ::.::::: :::.:::::: ::.:. ::::::.: .::::
XP_005 SSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT
180 190 200 210 220 230
190 200 210 220 230
pF1KB8 ERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAE----PEQDCAVTSGEELL-ALP--
::.:::::::::::.::.. : .: :. :: . .. : ..: . :. ..:
XP_005 ERQIKIWFQNRRMKYKKDQ-KGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE
240 250 260 270 280 290
240 250 260 270 280
pF1KB8 PPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
: :: . :: . . :::. . :: . : ::.
XP_005 PQSPPPFSKPPQGTYG-----LPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPH
300 310 320 330 340
XP_005 AHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLG
350 360 370 380 390 400
>>XP_005249789 (OMIM: 142954) PREDICTED: homeobox protei (443 aa)
initn: 453 init1: 310 opt: 463 Z-score: 281.5 bits: 60.6 E(85289): 6.1e-09
Smith-Waterman score: 477; 35.4% identity (55.4% similar) in 316 aa overlap (2-281:27-327)
10 20
pF1KB8 MNGEEQYYAAT-------QLYKDPCAFQR----GP
:...: : :. . .. :..: :
XP_005 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG
10 20 30 40 50 60
30 40 50 60 70
pF1KB8 APEFSASPPACLYMGRQPP--PP----PP-HPFPGALGALEQGSPPDISPYEVPPLADDP
:. ::: :: :: :: :: : .: .::. .: :: : :
XP_005 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHP-PPPQAAPPAPQPPQPAPQ--PP-APTP
70 80 90 100 110
80 90 100 110 120 130
pF1KB8 AVAHLHHHLPAQLALPHPPAG--PFP-EGAEPGVLEEPNRVQLPFPWMKSTKAHAWK---
:. : . : : :. : : ..:. .:. :. .. ::::: .. .. .
XP_005 AAPP-----PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTS
120 130 140 150 160 170
140 150 160 170 180
pF1KB8 ----GQWAGGAYAAEPEEN-KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLT
:. .: . . . ::.::::: :::.:::::: ::.:. ::::::.: .::::
XP_005 SSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT
180 190 200 210 220 230
190 200 210 220 230
pF1KB8 ERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAE----PEQDCAVTSGEELL-ALP--
::.:::::::::::.::.. : .: :. :: . .. : ..: . :. ..:
XP_005 ERQIKIWFQNRRMKYKKDQ-KGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE
240 250 260 270 280 290
240 250 260 270 280
pF1KB8 PPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
: :: . :: . . :::. . :: . : ::.
XP_005 PQSPPPFSKPPQGTYG-----LPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPH
300 310 320 330 340
XP_005 AHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLG
350 360 370 380 390 400
>>XP_006715778 (OMIM: 142954) PREDICTED: homeobox protei (443 aa)
initn: 453 init1: 310 opt: 463 Z-score: 281.5 bits: 60.6 E(85289): 6.1e-09
Smith-Waterman score: 477; 35.4% identity (55.4% similar) in 316 aa overlap (2-281:27-327)
10 20
pF1KB8 MNGEEQYYAAT-------QLYKDPCAFQR----GP
:...: : :. . .. :..: :
XP_006 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG
10 20 30 40 50 60
30 40 50 60 70
pF1KB8 APEFSASPPACLYMGRQPP--PP----PP-HPFPGALGALEQGSPPDISPYEVPPLADDP
:. ::: :: :: :: :: : .: .::. .: :: : :
XP_006 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHP-PPPQAAPPAPQPPQPAPQ--PP-APTP
70 80 90 100 110
80 90 100 110 120 130
pF1KB8 AVAHLHHHLPAQLALPHPPAG--PFP-EGAEPGVLEEPNRVQLPFPWMKSTKAHAWK---
:. : . : : :. : : ..:. .:. :. .. ::::: .. .. .
XP_006 AAPP-----PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTS
120 130 140 150 160 170
140 150 160 170 180
pF1KB8 ----GQWAGGAYAAEPEEN-KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLT
:. .: . . . ::.::::: :::.:::::: ::.:. ::::::.: .::::
XP_006 SSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT
180 190 200 210 220 230
190 200 210 220 230
pF1KB8 ERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAE----PEQDCAVTSGEELL-ALP--
::.:::::::::::.::.. : .: :. :: . .. : ..: . :. ..:
XP_006 ERQIKIWFQNRRMKYKKDQ-KGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE
240 250 260 270 280 290
240 250 260 270 280
pF1KB8 PPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
: :: . :: . . :::. . :: . : ::.
XP_006 PQSPPPFSKPPQGTYG-----LPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPH
300 310 320 330 340
XP_006 AHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLG
350 360 370 380 390 400
>>XP_011513645 (OMIM: 142954) PREDICTED: homeobox protei (443 aa)
initn: 453 init1: 310 opt: 463 Z-score: 281.5 bits: 60.6 E(85289): 6.1e-09
Smith-Waterman score: 477; 35.4% identity (55.4% similar) in 316 aa overlap (2-281:27-327)
10 20
pF1KB8 MNGEEQYYAAT-------QLYKDPCAFQR----GP
:...: : :. . .. :..: :
XP_011 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG
10 20 30 40 50 60
30 40 50 60 70
pF1KB8 APEFSASPPACLYMGRQPP--PP----PP-HPFPGALGALEQGSPPDISPYEVPPLADDP
:. ::: :: :: :: :: : .: .::. .: :: : :
XP_011 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHP-PPPQAAPPAPQPPQPAPQ--PP-APTP
70 80 90 100 110
80 90 100 110 120 130
pF1KB8 AVAHLHHHLPAQLALPHPPAG--PFP-EGAEPGVLEEPNRVQLPFPWMKSTKAHAWK---
:. : . : : :. : : ..:. .:. :. .. ::::: .. .. .
XP_011 AAPP-----PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTS
120 130 140 150 160 170
140 150 160 170 180
pF1KB8 ----GQWAGGAYAAEPEEN-KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLT
:. .: . . . ::.::::: :::.:::::: ::.:. ::::::.: .::::
XP_011 SSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT
180 190 200 210 220 230
190 200 210 220 230
pF1KB8 ERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAE----PEQDCAVTSGEELL-ALP--
::.:::::::::::.::.. : .: :. :: . .. : ..: . :. ..:
XP_011 ERQIKIWFQNRRMKYKKDQ-KGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE
240 250 260 270 280 290
240 250 260 270 280
pF1KB8 PPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
: :: . :: . . :::. . :: . : ::.
XP_011 PQSPPPFSKPPQGTYG-----LPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPH
300 310 320 330 340
XP_011 AHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLG
350 360 370 380 390 400
>>XP_005249787 (OMIM: 142954) PREDICTED: homeobox protei (443 aa)
initn: 453 init1: 310 opt: 463 Z-score: 281.5 bits: 60.6 E(85289): 6.1e-09
Smith-Waterman score: 477; 35.4% identity (55.4% similar) in 316 aa overlap (2-281:27-327)
10 20
pF1KB8 MNGEEQYYAAT-------QLYKDPCAFQR----GP
:...: : :. . .. :..: :
XP_005 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG
10 20 30 40 50 60
30 40 50 60 70
pF1KB8 APEFSASPPACLYMGRQPP--PP----PP-HPFPGALGALEQGSPPDISPYEVPPLADDP
:. ::: :: :: :: :: : .: .::. .: :: : :
XP_005 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHP-PPPQAAPPAPQPPQPAPQ--PP-APTP
70 80 90 100 110
80 90 100 110 120 130
pF1KB8 AVAHLHHHLPAQLALPHPPAG--PFP-EGAEPGVLEEPNRVQLPFPWMKSTKAHAWK---
:. : . : : :. : : ..:. .:. :. .. ::::: .. .. .
XP_005 AAPP-----PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTS
120 130 140 150 160 170
140 150 160 170 180
pF1KB8 ----GQWAGGAYAAEPEEN-KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLT
:. .: . . . ::.::::: :::.:::::: ::.:. ::::::.: .::::
XP_005 SSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT
180 190 200 210 220 230
190 200 210 220 230
pF1KB8 ERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAE----PEQDCAVTSGEELL-ALP--
::.:::::::::::.::.. : .: :. :: . .. : ..: . :. ..:
XP_005 ERQIKIWFQNRRMKYKKDQ-KGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE
240 250 260 270 280 290
240 250 260 270 280
pF1KB8 PPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
: :: . :: . . :::. . :: . : ::.
XP_005 PQSPPPFSKPPQGTYG-----LPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPH
300 310 320 330 340
XP_005 AHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLG
350 360 370 380 390 400
>>NP_705895 (OMIM: 142954) homeobox protein Hox-A3 isofo (443 aa)
initn: 453 init1: 310 opt: 463 Z-score: 281.5 bits: 60.6 E(85289): 6.1e-09
Smith-Waterman score: 477; 35.4% identity (55.4% similar) in 316 aa overlap (2-281:27-327)
10 20
pF1KB8 MNGEEQYYAAT-------QLYKDPCAFQR----GP
:...: : :. . .. :..: :
NP_705 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG
10 20 30 40 50 60
30 40 50 60 70
pF1KB8 APEFSASPPACLYMGRQPP--PP----PP-HPFPGALGALEQGSPPDISPYEVPPLADDP
:. ::: :: :: :: :: : .: .::. .: :: : :
NP_705 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHP-PPPQAAPPAPQPPQPAPQ--PP-APTP
70 80 90 100 110
80 90 100 110 120 130
pF1KB8 AVAHLHHHLPAQLALPHPPAG--PFP-EGAEPGVLEEPNRVQLPFPWMKSTKAHAWK---
:. : . : : :. : : ..:. .:. :. .. ::::: .. .. .
NP_705 AAPP-----PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTS
120 130 140 150 160 170
140 150 160 170 180
pF1KB8 ----GQWAGGAYAAEPEEN-KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLT
:. .: . . . ::.::::: :::.:::::: ::.:. ::::::.: .::::
NP_705 SSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT
180 190 200 210 220 230
190 200 210 220 230
pF1KB8 ERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAE----PEQDCAVTSGEELL-ALP--
::.:::::::::::.::.. : .: :. :: . .. : ..: . :. ..:
NP_705 ERQIKIWFQNRRMKYKKDQ-KGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE
240 250 260 270 280 290
240 250 260 270 280
pF1KB8 PPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
: :: . :: . . :::. . :: . : ::.
NP_705 PQSPPPFSKPPQGTYG-----LPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPH
300 310 320 330 340
NP_705 AHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLG
350 360 370 380 390 400
>>NP_109377 (OMIM: 142954) homeobox protein Hox-A3 isofo (443 aa)
initn: 453 init1: 310 opt: 463 Z-score: 281.5 bits: 60.6 E(85289): 6.1e-09
Smith-Waterman score: 477; 35.4% identity (55.4% similar) in 316 aa overlap (2-281:27-327)
10 20
pF1KB8 MNGEEQYYAAT-------QLYKDPCAFQR----GP
:...: : :. . .. :..: :
NP_109 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG
10 20 30 40 50 60
30 40 50 60 70
pF1KB8 APEFSASPPACLYMGRQPP--PP----PP-HPFPGALGALEQGSPPDISPYEVPPLADDP
:. ::: :: :: :: :: : .: .::. .: :: : :
NP_109 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHP-PPPQAAPPAPQPPQPAPQ--PP-APTP
70 80 90 100 110
80 90 100 110 120 130
pF1KB8 AVAHLHHHLPAQLALPHPPAG--PFP-EGAEPGVLEEPNRVQLPFPWMKSTKAHAWK---
:. : . : : :. : : ..:. .:. :. .. ::::: .. .. .
NP_109 AAPP-----PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTS
120 130 140 150 160 170
140 150 160 170 180
pF1KB8 ----GQWAGGAYAAEPEEN-KRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLT
:. .: . . . ::.::::: :::.:::::: ::.:. ::::::.: .::::
NP_109 SSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT
180 190 200 210 220 230
190 200 210 220 230
pF1KB8 ERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAE----PEQDCAVTSGEELL-ALP--
::.:::::::::::.::.. : .: :. :: . .. : ..: . :. ..:
NP_109 ERQIKIWFQNRRMKYKKDQ-KGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYE
240 250 260 270 280 290
240 250 260 270 280
pF1KB8 PPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
: :: . :: . . :::. . :: . : ::.
NP_109 PQSPPPFSKPPQGTYG-----LPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPH
300 310 320 330 340
NP_109 AHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLG
350 360 370 380 390 400
>>NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [Homo (320 aa)
initn: 383 init1: 290 opt: 394 Z-score: 244.5 bits: 53.3 E(85289): 7e-07
Smith-Waterman score: 415; 36.8% identity (57.7% similar) in 239 aa overlap (17-249:101-315)
10 20 30 40
pF1KB8 MNGEEQYYAATQLYKDPCAFQRGPAPEFSASPPACLYMGRQPPPPP
: ... : .: . :: . .:::
NP_002 ASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASP---GRPP----QPEQPPAQA
80 90 100 110 120
50 60 70 80 90 100
pF1KB8 PHPFPG--ALGALEQGSPPDISPYEVPPLADDPAVAHLHHHLPAQLALPHPPAGPFPEGA
: : : .:. :: ..: ::: : : . :. : :: :. :
NP_002 KGPAHGLHASHVLQPQLPPPLQPRAVPPAA--PRRCEAAPATPGVPAGGSAPACPL-LLA
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB8 EPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKE
. . : .. . .::::. .. : . .. :: :: ::.:::::: :.::::::
NP_002 DKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNGG----EP---KRSRTAYTRQQVLELEKE
190 200 210 220 230
170 180 190 200 210 220
pF1KB8 FLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEED----KKRGGGTAVGGGGV
: ::.:..: ::.:.: : :.::..:::::::::::::.. : :....: ...:
NP_002 FHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAG-
240 250 260 270 280 290
230 240 250 260 270 280
pF1KB8 AEPEQDCAVTSGEELLALPPPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQ
: . : . : : : :. ..:
NP_002 --PPGKAQTQSPH----LHPHPHPSTSTPVPSSI
300 310 320
>>NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [Homo (356 aa)
initn: 380 init1: 281 opt: 393 Z-score: 243.4 bits: 53.2 E(85289): 8.1e-07
Smith-Waterman score: 406; 34.8% identity (51.5% similar) in 264 aa overlap (45-282:44-302)
20 30 40 50 60 70
pF1KB8 KDPCAFQRGPAPEFSASPPACLYMGRQPPPPPPHPFPGALGALEQGSPPDISPYEVPPLA
::: :: .. .:. :. :
NP_002 SQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPFEQTFPSLQPGASTLQRPRSQKRAE
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB8 DDPAVAHLHHHLPAQLALPH-PPAGPFPEGAEPGVLEEPNRVQL-PFPWMKSTKAHAWKG
: ::. : :: ::: :: : ..:.. : : ... : . .
NP_002 DGPALPP-----PPPPPLPAAPPAPEFPWMKEKKSAKKPSQSATSPSPAASAVPASGVGS
80 90 100 110 120
140 150 160 170 180 190
pF1KB8 QWAG-GAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIK
: : : .: ::::: .::::::::: ::::. ::::::.:..:.::::..:
NP_002 PADGLGLPEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVK
130 140 150 160 170 180
200 210 220 230
pF1KB8 IWFQNRRMKWKKEEDKKR--GGGTAVGGG--GVAEPEQDCAVTSGE--------ELLALP
.:::::::: :.. .... : : :. . .: .. :.. : : :
NP_002 VWFQNRRMKHKRQTQHREPPDGEPACPGALEDICDPAEEPAASPGGPSASRAAWEACCHP
190 200 210 220 230 240
240 250 260 270 280
pF1KB8 PPPPPGGAVPPAAPVAAR-EG----------RLPPGLSASPQPSSVAPRRPQEPR
: ::. :.:.: :: : :: .: : .: : . :
NP_002 PEVVPGALSADPRPLAVRLEGAGASSPGCALRGAGGLEPGPLPEDVFSGRQDSPFLPDLN
250 260 270 280 290 300
NP_002 FFAADSCLQLSGGLSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP
310 320 330 340 350
283 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:33:26 2016 done: Fri Nov 4 16:33:28 2016
Total Scan time: 8.220 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]