Result of FASTA (ccds) for
pFN21AB8891
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8891, 211 aa
1>>>pF1KB8891 211 - 211 aa - 211 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3430+/-0.000594; mu= 15.2572+/- 0.036
mean_var=83.6250+/-16.374, 0's: 0 Z-trim(113.6): 22 B-trim: 0 in 0/52
Lambda= 0.140251
statistics sampled from 14217 (14238) to 14217 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.437), width: 16
Scan time: 2.330
The best scores are: opt bits E(32554)
CCDS3922.1 GDNF gene_id:2668|Hs108|chr5 ( 211) 1441 300.2 6.3e-82
CCDS54845.1 GDNF gene_id:2668|Hs108|chr5 ( 228) 1441 300.2 6.7e-82
CCDS3923.1 GDNF gene_id:2668|Hs108|chr5 ( 185) 1097 230.5 5.2e-61
CCDS54846.1 GDNF gene_id:2668|Hs108|chr5 ( 202) 1097 230.5 5.5e-61
CCDS75237.1 GDNF gene_id:2668|Hs108|chr5 ( 159) 1089 228.8 1.4e-60
CCDS12151.1 NRTN gene_id:4902|Hs108|chr19 ( 197) 336 76.6 1.2e-14
>>CCDS3922.1 GDNF gene_id:2668|Hs108|chr5 (211 aa)
initn: 1441 init1: 1441 opt: 1441 Z-score: 1584.3 bits: 300.2 E(32554): 6.3e-82
Smith-Waterman score: 1441; 100.0% identity (100.0% similar) in 211 aa overlap (1-211:1-211)
10 20 30 40 50 60
pF1KB8 MKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRAPFALSSDSNMPEDYPDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 MKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRAPFALSSDSNMPEDYPDQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 FDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 TAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCR
130 140 150 160 170 180
190 200 210
pF1KB8 PIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
:::::::::::::::::::::::::::::::
CCDS39 PIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
190 200 210
>>CCDS54845.1 GDNF gene_id:2668|Hs108|chr5 (228 aa)
initn: 1441 init1: 1441 opt: 1441 Z-score: 1583.8 bits: 300.2 E(32554): 6.7e-82
Smith-Waterman score: 1441; 100.0% identity (100.0% similar) in 211 aa overlap (1-211:18-228)
10 20 30 40
pF1KB8 MKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRA
:::::::::::::::::::::::::::::::::::::::::::
CCDS54 MQSLPNSNGAAAGRDFKMKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 PFALSSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PFALSSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENS
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB8 RGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 RGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNL
130 140 150 160 170 180
170 180 190 200 210
pF1KB8 SRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
190 200 210 220
>>CCDS3923.1 GDNF gene_id:2668|Hs108|chr5 (185 aa)
initn: 1097 init1: 1097 opt: 1097 Z-score: 1208.9 bits: 230.5 E(32554): 5.2e-61
Smith-Waterman score: 1197; 87.2% identity (87.7% similar) in 211 aa overlap (1-211:1-185)
10 20 30 40 50 60
pF1KB8 MKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRAPFALSSDSNMPEDYPDQ
:::::::::::::::::::::::: .:::::::::
CCDS39 MKLWDVVAVCLVLLHTASAFPLPA--------------------------ANMPEDYPDQ
10 20 30
70 80 90 100 110 120
pF1KB8 FDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 FDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB8 TAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 TAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCR
100 110 120 130 140 150
190 200 210
pF1KB8 PIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
:::::::::::::::::::::::::::::::
CCDS39 PIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
160 170 180
>>CCDS54846.1 GDNF gene_id:2668|Hs108|chr5 (202 aa)
initn: 1097 init1: 1097 opt: 1097 Z-score: 1208.4 bits: 230.5 E(32554): 5.5e-61
Smith-Waterman score: 1197; 87.2% identity (87.7% similar) in 211 aa overlap (1-211:18-202)
10 20 30 40
pF1KB8 MKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRA
::::::::::::::::::::::::
CCDS54 MQSLPNSNGAAAGRDFKMKLWDVVAVCLVLLHTASAFPLPA-------------------
10 20 30 40
50 60 70 80 90 100
pF1KB8 PFALSSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENS
.::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 -------ANMPEDYPDQFDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENS
50 60 70 80 90
110 120 130 140 150 160
pF1KB8 RGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 RGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNL
100 110 120 130 140 150
170 180 190 200 210
pF1KB8 SRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
160 170 180 190 200
>>CCDS75237.1 GDNF gene_id:2668|Hs108|chr5 (159 aa)
initn: 1089 init1: 1089 opt: 1089 Z-score: 1201.0 bits: 228.8 E(32554): 1.4e-60
Smith-Waterman score: 1089; 100.0% identity (100.0% similar) in 159 aa overlap (53-211:1-159)
30 40 50 60 70 80
pF1KB8 PAGKRPPEAPAEDRSLGRRRAPFALSSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQ
::::::::::::::::::::::::::::::
CCDS75 MPEDYPDQFDDVMDFIQATIKRLKRSPDKQ
10 20 30
90 100 110 120 130 140
pF1KB8 MAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 MAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIF
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB8 RYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 RYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRK
100 110 120 130 140 150
210
pF1KB8 HSAKRCGCI
:::::::::
CCDS75 HSAKRCGCI
>>CCDS12151.1 NRTN gene_id:4902|Hs108|chr19 (197 aa)
initn: 322 init1: 156 opt: 336 Z-score: 376.3 bits: 76.6 E(32554): 1.2e-14
Smith-Waterman score: 336; 41.7% identity (71.3% similar) in 115 aa overlap (98-211:87-197)
70 80 90 100 110 120
pF1KB8 IQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNV
:.:. :...: : : : : ... :
CCDS12 YRALLQGAPDAMELRELTPWAGRPPGPRRRAGPRRRRARARLGARP----CGLRELEVRV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 TDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKV-GQACCRPIAFDD
..::::: . : ..::::.:.:.:: .:: :. : . ::: ..: .: :::: :..:
CCDS12 SELGLGYASDETVLFRYCAGACEAAARVYDLGLRRLRQRRRLRRERVRAQPCCRPTAYED
120 130 140 150 160 170
190 200 210
pF1KB8 DLSFLDDNLVYHILRKHSAKRCGCI
..:::: . :: ... ::..:.:.
CCDS12 EVSFLDAHSRYHTVHELSARECACV
180 190
211 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:22:26 2016 done: Fri Nov 4 16:22:26 2016
Total Scan time: 2.330 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]