Result of FASTA (omim) for
pFN21AB8839
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8839, 466 aa
1>>>pF1KB8839 466 - 466 aa - 466 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7542+/-0.000442; mu= 16.8760+/- 0.028
mean_var=138.7224+/-32.104, 0's: 0 Z-trim(113.0): 497 B-trim: 2145 in 2/54
Lambda= 0.108893
statistics sampled from 21371 (22094) to 21371 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.615), E-opt: 0.2 (0.259), width: 16
Scan time: 8.250
The best scores are: opt bits E(85289)
XP_011514071 (OMIM: 118493) PREDICTED: muscarinic ( 466) 3081 496.3 7.2e-140
NP_001006630 (OMIM: 118493) muscarinic acetylcholi ( 466) 3081 496.3 7.2e-140
NP_001006633 (OMIM: 118493) muscarinic acetylcholi ( 466) 3081 496.3 7.2e-140
NP_001006631 (OMIM: 118493) muscarinic acetylcholi ( 466) 3081 496.3 7.2e-140
NP_001006632 (OMIM: 118493) muscarinic acetylcholi ( 466) 3081 496.3 7.2e-140
NP_000730 (OMIM: 118493) muscarinic acetylcholine ( 466) 3081 496.3 7.2e-140
NP_001006628 (OMIM: 118493) muscarinic acetylcholi ( 466) 3081 496.3 7.2e-140
NP_001006627 (OMIM: 118493) muscarinic acetylcholi ( 466) 3081 496.3 7.2e-140
NP_001006629 (OMIM: 118493) muscarinic acetylcholi ( 466) 3081 496.3 7.2e-140
NP_000732 (OMIM: 118495) muscarinic acetylcholine ( 479) 1744 286.3 1.2e-76
NP_000731 (OMIM: 100100,118494) muscarinic acetylc ( 590) 957 162.8 2.3e-39
XP_016855642 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_005273089 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_016855643 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_016855650 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_016855647 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_016855651 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_011542348 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_016855644 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_016855645 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_011542346 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_016855648 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_011542347 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_016855641 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_011542349 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_011542345 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_016855652 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_016855649 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_016855646 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_011542343 (OMIM: 100100,118494) PREDICTED: musc ( 590) 957 162.8 2.3e-39
XP_011543044 (OMIM: 118510) PREDICTED: muscarinic ( 460) 919 156.7 1.3e-37
NP_000729 (OMIM: 118510) muscarinic acetylcholine ( 460) 919 156.7 1.3e-37
NP_036257 (OMIM: 118496) muscarinic acetylcholine ( 532) 897 153.3 1.5e-36
NP_001307846 (OMIM: 118496) muscarinic acetylcholi ( 532) 897 153.3 1.5e-36
NP_000673 (OMIM: 104260,607876) alpha-2B adrenergi ( 450) 479 87.5 8e-17
NP_009163 (OMIM: 604525) histamine H3 receptor [Ho ( 445) 470 86.1 2.1e-16
XP_005260323 (OMIM: 604525) PREDICTED: histamine H ( 453) 470 86.1 2.1e-16
NP_000515 (OMIM: 109760,614674) 5-hydroxytryptamin ( 422) 455 83.7 1e-15
XP_011531955 (OMIM: 600167) PREDICTED: histamine H ( 487) 452 83.3 1.6e-15
NP_001091681 (OMIM: 600167) histamine H1 receptor ( 487) 452 83.3 1.6e-15
NP_001091683 (OMIM: 600167) histamine H1 receptor ( 487) 452 83.3 1.6e-15
XP_016861773 (OMIM: 600167) PREDICTED: histamine H ( 487) 452 83.3 1.6e-15
NP_000852 (OMIM: 600167) histamine H1 receptor [Ho ( 487) 452 83.3 1.6e-15
NP_001091682 (OMIM: 600167) histamine H1 receptor ( 487) 452 83.3 1.6e-15
XP_011531954 (OMIM: 600167) PREDICTED: histamine H ( 487) 452 83.3 1.6e-15
XP_016861772 (OMIM: 600167) PREDICTED: histamine H ( 487) 452 83.3 1.6e-15
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390) 443 81.8 3.7e-15
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308) 439 81.0 4.9e-15
XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A ad ( 317) 439 81.1 5e-15
XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A ad ( 324) 439 81.1 5.1e-15
>>XP_011514071 (OMIM: 118493) PREDICTED: muscarinic acet (466 aa)
initn: 3081 init1: 3081 opt: 3081 Z-score: 2632.1 bits: 496.3 E(85289): 7.2e-140
Smith-Waterman score: 3081; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466)
10 20 30 40 50 60
pF1KB8 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
370 380 390 400 410 420
430 440 450 460
pF1KB8 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
430 440 450 460
>>NP_001006630 (OMIM: 118493) muscarinic acetylcholine r (466 aa)
initn: 3081 init1: 3081 opt: 3081 Z-score: 2632.1 bits: 496.3 E(85289): 7.2e-140
Smith-Waterman score: 3081; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466)
10 20 30 40 50 60
pF1KB8 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
370 380 390 400 410 420
430 440 450 460
pF1KB8 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
430 440 450 460
>>NP_001006633 (OMIM: 118493) muscarinic acetylcholine r (466 aa)
initn: 3081 init1: 3081 opt: 3081 Z-score: 2632.1 bits: 496.3 E(85289): 7.2e-140
Smith-Waterman score: 3081; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466)
10 20 30 40 50 60
pF1KB8 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
370 380 390 400 410 420
430 440 450 460
pF1KB8 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
430 440 450 460
>>NP_001006631 (OMIM: 118493) muscarinic acetylcholine r (466 aa)
initn: 3081 init1: 3081 opt: 3081 Z-score: 2632.1 bits: 496.3 E(85289): 7.2e-140
Smith-Waterman score: 3081; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466)
10 20 30 40 50 60
pF1KB8 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
370 380 390 400 410 420
430 440 450 460
pF1KB8 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
430 440 450 460
>>NP_001006632 (OMIM: 118493) muscarinic acetylcholine r (466 aa)
initn: 3081 init1: 3081 opt: 3081 Z-score: 2632.1 bits: 496.3 E(85289): 7.2e-140
Smith-Waterman score: 3081; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466)
10 20 30 40 50 60
pF1KB8 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
370 380 390 400 410 420
430 440 450 460
pF1KB8 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
430 440 450 460
>>NP_000730 (OMIM: 118493) muscarinic acetylcholine rece (466 aa)
initn: 3081 init1: 3081 opt: 3081 Z-score: 2632.1 bits: 496.3 E(85289): 7.2e-140
Smith-Waterman score: 3081; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466)
10 20 30 40 50 60
pF1KB8 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
370 380 390 400 410 420
430 440 450 460
pF1KB8 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
430 440 450 460
>>NP_001006628 (OMIM: 118493) muscarinic acetylcholine r (466 aa)
initn: 3081 init1: 3081 opt: 3081 Z-score: 2632.1 bits: 496.3 E(85289): 7.2e-140
Smith-Waterman score: 3081; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466)
10 20 30 40 50 60
pF1KB8 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
370 380 390 400 410 420
430 440 450 460
pF1KB8 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
430 440 450 460
>>NP_001006627 (OMIM: 118493) muscarinic acetylcholine r (466 aa)
initn: 3081 init1: 3081 opt: 3081 Z-score: 2632.1 bits: 496.3 E(85289): 7.2e-140
Smith-Waterman score: 3081; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466)
10 20 30 40 50 60
pF1KB8 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
370 380 390 400 410 420
430 440 450 460
pF1KB8 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
430 440 450 460
>>NP_001006629 (OMIM: 118493) muscarinic acetylcholine r (466 aa)
initn: 3081 init1: 3081 opt: 3081 Z-score: 2632.1 bits: 496.3 E(85289): 7.2e-140
Smith-Waterman score: 3081; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466)
10 20 30 40 50 60
pF1KB8 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
370 380 390 400 410 420
430 440 450 460
pF1KB8 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
430 440 450 460
>>NP_000732 (OMIM: 118495) muscarinic acetylcholine rece (479 aa)
initn: 1686 init1: 1158 opt: 1744 Z-score: 1496.8 bits: 286.3 E(85289): 1.2e-76
Smith-Waterman score: 1744; 57.7% identity (79.4% similar) in 480 aa overlap (1-466:7-479)
10 20 30 40 50
pF1KB8 MNNSTNSSNNSLALTSP---YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVN
.:.:..... :. .: :.: :.:::. :.:::::::..::::::.:::::
NP_000 MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 RHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASV
:.::::::::::::::::::::.:::::::.: . :::::: ::::::::::::::::::
NP_000 RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 MNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTV
:::::::::::::::::::::..:::::::.::::::::::.:::::::::::.:: :::
NP_000 MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 EDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPV
:..:.:::.:: :::::::::::::::.:::::: ::: ::.::..: . : ..
NP_000 PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
190 200 210 220 230 240
240 250 260 270 280
pF1KB8 SPSLVQGRIVKPNNNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTS
. ..... ..: . .. : .. . :...:.... : : : .:..::.:.:
NP_000 TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVA--DKDTSNESSS
250 260 270 280 290
290 300 310 320 330 340
pF1KB8 VSAV-------ASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTN
::. :... : : . .. . :. . :.: :: .. :.
NP_000 GSATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQT-GNECV---
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB8 TTVEVVGSSGQNGDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITW
:..:.: .. : . ::::...... : ::. .::.::::::.:::::::.::
NP_000 TAIEIVPAT-PAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTW
360 370 380 390 400 410
410 420 430 440 450 460
pF1KB8 APYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYK
.:::::::.:::: :::.:::.:::::::.::::::::::::::::::::.:::.:.:.
NP_000 TPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYR
420 430 440 450 460 470
pF1KB8 NIGATR
:::..:
NP_000 NIGTAR
466 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:01:05 2016 done: Fri Nov 4 16:01:06 2016
Total Scan time: 8.250 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]