Result of FASTA (ccds) for
pFN21AB8786
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8786, 297 aa
1>>>pF1KB8786 297 - 297 aa - 297 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5534+/-0.00135; mu= 14.4714+/- 0.079
mean_var=265.0492+/-122.882, 0's: 0 Z-trim(101.4): 209 B-trim: 847 in 2/44
Lambda= 0.078779
statistics sampled from 6161 (6511) to 6161 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.535), E-opt: 0.2 (0.2), width: 16
Scan time: 2.250
The best scores are: opt bits E(32554)
CCDS11869.1 MC2R gene_id:4158|Hs108|chr18 ( 297) 1960 237.1 1.2e-62
CCDS11868.1 MC5R gene_id:4161|Hs108|chr18 ( 325) 942 121.5 8.5e-28
CCDS11976.1 MC4R gene_id:4160|Hs108|chr18 ( 332) 934 120.6 1.6e-27
CCDS56011.1 MC1R gene_id:4157|Hs108|chr16 ( 317) 750 99.6 3.1e-21
CCDS13449.2 MC3R gene_id:4159|Hs108|chr20 ( 323) 583 80.7 1.6e-15
>>CCDS11869.1 MC2R gene_id:4158|Hs108|chr18 (297 aa)
initn: 1960 init1: 1960 opt: 1960 Z-score: 1238.1 bits: 237.1 E(32554): 1.2e-62
Smith-Waterman score: 1960; 100.0% identity (100.0% similar) in 297 aa overlap (1-297:1-297)
10 20 30 40 50 60
pF1KB8 MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVFKNKNLQAPMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVFKNKNLQAPMY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLFVLSLLGSIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 FFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLFVLSLLGSIFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSHHVPTVITFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSHHVPTVITFTS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LFPLMLVFILCLYVHMFLLARSHTRKISTLPRANMKGAITLTILLGVFIFCWAPFVLHVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LFPLMLVFILCLYVHMFLLARSHTRKISTLPRANMKGAITLTILLGVFIFCWAPFVLHVL
190 200 210 220 230 240
250 260 270 280 290
pF1KB8 LMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSPELRDAFKKMIFCSRYW
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSPELRDAFKKMIFCSRYW
250 260 270 280 290
>>CCDS11868.1 MC5R gene_id:4161|Hs108|chr18 (325 aa)
initn: 930 init1: 559 opt: 942 Z-score: 612.5 bits: 121.5 E(32554): 8.5e-28
Smith-Waterman score: 942; 46.5% identity (77.8% similar) in 288 aa overlap (13-293:25-312)
10 20 30 40
pF1KB8 MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLA
:. ..: : . . :.:.:......:::..:. :
CCDS11 MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 VFKNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDS
. :::::..:::::.::::..::: :. . :.: : : : .: .: :...::
CCDS11 IVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDS
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB8 LFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIF
.. .:...:. :: .::.:::.:::.::::: :.: ::. .... ::.:::: ::.....
CCDS11 MICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILY
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB8 SHHVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLP-------RANMKGAITL
:. . ... . :.: :: ... ::.:::::::.:...:..:: :..:.::.:.
CCDS11 SESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTV
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB8 TILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSP
:.::::: ::::: ::. :: ::.: ::. .:: :.. .:::::.:.::.::::::
CCDS11 TMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQ
250 260 270 280 290 300
290
pF1KB8 ELRDAFKKMIFCSRYW
:.: .::..: :
CCDS11 EMRKTFKEIICCRGFRIACSFPRRD
310 320
>>CCDS11976.1 MC4R gene_id:4160|Hs108|chr18 (332 aa)
initn: 950 init1: 397 opt: 934 Z-score: 607.6 bits: 120.6 E(32554): 1.6e-27
Smith-Waterman score: 934; 47.3% identity (77.7% similar) in 296 aa overlap (6-293:26-319)
10 20 30
pF1KB8 MKHIINSYENINNTARNNSDC-PRVVLPEEIFFTISIVGV
:. :.... . ... : .. . :.: :......
CCDS11 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGK-GYSDGGCYEQLFVSPEVFVTLGVISL
10 20 30 40 50
40 50 60 70 80 90
pF1KB8 LENLIVLLAVFKNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFE
:::..:..:. :::::..::::::::::..::: :. . :.:.: : : . ::
CCDS11 LENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQ-SFT
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB8 TTADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCT
.. :..:::.. :::.:: :: ::.:::.:::.::.::.:.:..:. .... ::. ::
CCDS11 VNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACT
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB8 GTGITMVIFSHHVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLPR-------
.:: ..:.: ..: . ..: ::... :::::::.:: : ..:..::
CCDS11 VSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQG
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB8 ANMKGAITLTILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVID
::::::::::::.:::. ::::: ::.... ::.::::.:.:: :.. .:::::..::
CCDS11 ANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIID
240 250 260 270 280 290
280 290
pF1KB8 PFIYAFRSPELRDAFKKMIFCSRYW
:.:::.:: ::: .::..: :
CCDS11 PLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
300 310 320 330
>>CCDS56011.1 MC1R gene_id:4157|Hs108|chr16 (317 aa)
initn: 773 init1: 390 opt: 750 Z-score: 494.7 bits: 99.6 E(32554): 3.1e-21
Smith-Waterman score: 750; 40.7% identity (73.0% similar) in 285 aa overlap (21-297:35-317)
10 20 30 40 50
pF1KB8 MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVF
: .: . . .:.....:...:: .:. ..
CCDS56 GSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVVATIA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 KNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLF
::.::..::: ::: ::.::.: : ..::. .:.: . : : :.. :..:: .
CCDS56 KNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVIDVIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 VLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSH
:.:.:. :..::.::::.::.:::::::::. :. ....::. . . .. .
CCDS56 CSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFIAYYD
130 140 150 160 170 180
180 190 200 210 220
pF1KB8 HVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLPRAN--------MKGAITLT
:: ... .. .: :::.. :::::. : .:.. :. : . . .:::.:::
CCDS56 HVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLT
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB8 ILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSPE
::::.:..::.:: ::. :...:: .: :.: .. :.. ::.:::.:::.::::.: :
CCDS56 ILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQE
250 260 270 280 290 300
290
pF1KB8 LRDAFKKMIFCSRYW
:: ..:... :: :
CCDS56 LRRTLKEVLTCS--W
310
>>CCDS13449.2 MC3R gene_id:4159|Hs108|chr20 (323 aa)
initn: 951 init1: 583 opt: 583 Z-score: 392.1 bits: 80.7 E(32554): 1.6e-15
Smith-Waterman score: 940; 47.9% identity (79.8% similar) in 282 aa overlap (21-293:35-315)
10 20 30 40 50
pF1KB8 MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVF
: .: . :.:....::..:::..:.:::
CCDS13 CCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 KNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLF
.: ::..:::::.::::..::: :. . ::.:.: . . :: . .: :.:.::..
CCDS13 RNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 VLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSH
.::..:: .: .::.:::.:::.:::::::.:.:........::. : :......:.
CCDS13 CISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSE
130 140 150 160 170 180
180 190 200 210 220
pF1KB8 HVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLPRAN---------MKGAITL
... . ..: :.... :::::::.:: :...:..:: :. ::::.:.
CCDS13 SKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTI
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB8 TILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSP
:::::::::::::: ::..:. ::.:::: :: . :.. .:::::.::::.::::::
CCDS13 TILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSL
250 260 270 280 290 300
290
pF1KB8 ELRDAFKKMIFCSRYW
:::..:.. :.:
CCDS13 ELRNTFRE-ILCGCNGMNLG
310 320
297 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:36:43 2016 done: Fri Nov 4 15:36:44 2016
Total Scan time: 2.250 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]