Result of FASTA (omim) for
pFN21AB8766
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8766, 225 aa
1>>>pF1KB8766 225 - 225 aa - 225 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1093+/-0.000415; mu= 15.2515+/- 0.026
mean_var=67.3764+/-14.577, 0's: 0 Z-trim(111.5): 94 B-trim: 1047 in 1/49
Lambda= 0.156250
statistics sampled from 19993 (20103) to 19993 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.236), width: 16
Scan time: 5.960
The best scores are: opt bits E(85289)
NP_001161433 (OMIM: 611725,611726) BTB/POZ domain- ( 288) 376 93.7 3.4e-19
NP_694578 (OMIM: 611725,611726) BTB/POZ domain-con ( 289) 376 93.7 3.4e-19
XP_011535975 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 286) 232 61.2 2e-09
XP_011535974 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 304) 232 61.3 2.1e-09
XP_006714852 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 232 61.4 2.8e-09
XP_011535973 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 232 61.4 2.8e-09
XP_005268549 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 232 61.4 2.8e-09
XP_005268550 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 232 61.4 2.8e-09
NP_065819 (OMIM: 613423) BTB/POZ domain-containing ( 428) 232 61.4 2.8e-09
NP_955751 (OMIM: 607947) potassium channel regulat ( 229) 215 57.3 2.4e-08
NP_775876 (OMIM: 607947) potassium channel regulat ( 272) 215 57.4 2.8e-08
NP_076981 (OMIM: 615240) BTB/POZ domain-containing ( 234) 214 57.1 2.9e-08
XP_016882772 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 214 57.2 3.3e-08
NP_001123466 (OMIM: 615240) BTB/POZ domain-contain ( 283) 214 57.2 3.3e-08
XP_011525599 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 214 57.2 3.3e-08
XP_011525600 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 214 57.2 3.3e-08
NP_001123467 (OMIM: 615240) BTB/POZ domain-contain ( 283) 214 57.2 3.3e-08
NP_612453 (OMIM: 610521) BTB/POZ domain-containing ( 325) 212 56.8 5.1e-08
XP_011544085 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 347) 210 56.3 7.3e-08
NP_061865 (OMIM: 611285) BTB/POZ domain-containing ( 234) 199 53.7 3e-07
NP_001304328 (OMIM: 613421) BTB/POZ domain-contain ( 290) 200 54.0 3e-07
XP_016878595 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 173) 197 53.2 3.2e-07
XP_016878594 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 175) 197 53.2 3.2e-07
NP_849194 (OMIM: 608947) BTB/POZ domain-containing ( 329) 200 54.1 3.4e-07
NP_114160 (OMIM: 613421) BTB/POZ domain-containing ( 313) 198 53.6 4.4e-07
NP_001304324 (OMIM: 613421) BTB/POZ domain-contain ( 314) 198 53.6 4.4e-07
NP_001245150 (OMIM: 181270,613420) BTB/POZ domain- ( 257) 196 53.1 5.1e-07
NP_945342 (OMIM: 181270,613420) BTB/POZ domain-con ( 257) 196 53.1 5.1e-07
XP_016881197 (OMIM: 181270,613420) PREDICTED: BTB/ ( 257) 196 53.1 5.1e-07
NP_001129677 (OMIM: 181270,613420) BTB/POZ domain- ( 257) 196 53.1 5.1e-07
NP_001245151 (OMIM: 181270,613420) BTB/POZ domain- ( 265) 196 53.1 5.3e-07
XP_011522877 (OMIM: 613422) PREDICTED: BTB/POZ dom ( 226) 193 52.4 7.4e-07
NP_056168 (OMIM: 613422) BTB/POZ domain-containing ( 263) 193 52.4 8.4e-07
NP_001136202 (OMIM: 181270,613420) BTB/POZ domain- ( 865) 196 53.4 1.4e-06
NP_001269615 (OMIM: 616386,616398) BTB/POZ domain- ( 220) 188 51.2 1.6e-06
NP_001269614 (OMIM: 616386,616398) BTB/POZ domain- ( 225) 188 51.2 1.6e-06
XP_011528679 (OMIM: 616386,616398) PREDICTED: BTB/ ( 249) 188 51.3 1.8e-06
NP_078957 (OMIM: 616386,616398) BTB/POZ domain-con ( 297) 188 51.3 2e-06
XP_005261801 (OMIM: 616386,616398) PREDICTED: BTB/ ( 315) 188 51.3 2.1e-06
NP_001269613 (OMIM: 616386,616398) BTB/POZ domain- ( 321) 188 51.4 2.1e-06
XP_005261800 (OMIM: 616386,616398) PREDICTED: BTB/ ( 328) 188 51.4 2.2e-06
XP_005261799 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352) 188 51.4 2.3e-06
XP_005261798 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352) 188 51.4 2.3e-06
XP_011528676 (OMIM: 616386,616398) PREDICTED: BTB/ ( 370) 188 51.4 2.4e-06
NP_001306223 (OMIM: 613272) BTB/POZ domain-contain ( 813) 188 51.6 4.5e-06
NP_057205 (OMIM: 613272) BTB/POZ domain-containing ( 815) 188 51.6 4.5e-06
NP_066960 (OMIM: 191161) BTB/POZ domain-containing ( 316) 175 48.4 1.6e-05
XP_016880482 (OMIM: 191161) PREDICTED: BTB/POZ dom ( 391) 175 48.5 1.9e-05
NP_004967 (OMIM: 176258,616187) potassium voltage- ( 511) 151 43.1 0.001
XP_011518382 (OMIM: 176258,616187) PREDICTED: pota ( 535) 151 43.2 0.001
>>NP_001161433 (OMIM: 611725,611726) BTB/POZ domain-cont (288 aa)
initn: 503 init1: 249 opt: 376 Z-score: 465.5 bits: 93.7 E(85289): 3.4e-19
Smith-Waterman score: 481; 39.1% identity (63.4% similar) in 238 aa overlap (4-224:52-288)
10 20 30
pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMF
:: ::.:: :: :.::: . . :: ::
NP_001 DAEDDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMF
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB8 SSLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVPT-QHIPEVYREAQFYEIKPLVKLL
:. ::.:::.:::: .:.: .:..::.:..: ... ::.:::.: : ::.. :
NP_001 SGRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPRERVRAVYKEAQYYAIGPLLEQL
90 100 110 120 130 140
100 110 120 130 140
pF1KB8 EDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAIT--ARKSSVLVCLVETEEQ-D
:.: . ::.: :. :: .: :...:: .:..:: .:. :: ... ::. . :
NP_001 ENMQPLKGEKV-RQAFLGLMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPIT
150 160 170 180 190 200
150 160 170 180 190
pF1KB8 AYYSEVLCFLQ------DKKMFKSV----VKFGPWKAVLDNSDLMHCLEMDIKAQGYKVF
: .: :. : ..:. :.::::.:: : ::.::: :..::: :
NP_001 PYECPLLNSLRFERSESDGQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVD
210 220 230 240 250 260
200 210 220
pF1KB8 SKFYLTYPTKR-NEFHFN--IYSFTFTWW
. . . :... . :: : .::
NP_001 HQCIGVCDKHLVNHYYCKRPIYEFKITW
270 280
>>NP_694578 (OMIM: 611725,611726) BTB/POZ domain-contain (289 aa)
initn: 518 init1: 249 opt: 376 Z-score: 465.5 bits: 93.7 E(85289): 3.4e-19
Smith-Waterman score: 496; 39.3% identity (63.6% similar) in 239 aa overlap (4-225:52-289)
10 20 30
pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMF
:: ::.:: :: :.::: . . :: ::
NP_694 DAEDDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMF
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB8 SSLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVPT-QHIPEVYREAQFYEIKPLVKLL
:. ::.:::.:::: .:.: .:..::.:..: ... ::.:::.: : ::.. :
NP_694 SGRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPRERVRAVYKEAQYYAIGPLLEQL
90 100 110 120 130 140
100 110 120 130 140
pF1KB8 EDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAIT--ARKSSVLVCLVETEEQ-D
:.: . ::.: :. :: .: :...:: .:..:: .:. :: ... ::. . :
NP_694 ENMQPLKGEKV-RQAFLGLMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPIT
150 160 170 180 190 200
150 160 170 180 190
pF1KB8 AYYSEVLCFLQ------DKKMFKSV----VKFGPWKAVLDNSDLMHCLEMDIKAQGYKVF
: .: :. : ..:. :.::::.:: : ::.::: :..::: :
NP_694 PYECPLLNSLRFERSESDGQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVD
210 220 230 240 250 260
200 210 220
pF1KB8 SKFYLTYPTKR-NEFHFN--IYSFTFTWW
. . . :... . :: : .:::
NP_694 HQCIGVCDKHLVNHYYCKRPIYEFKITWW
270 280
>>XP_011535975 (OMIM: 613423) PREDICTED: BTB/POZ domain- (286 aa)
initn: 157 init1: 115 opt: 232 Z-score: 290.1 bits: 61.2 E(85289): 2e-09
Smith-Waterman score: 232; 48.0% identity (67.3% similar) in 98 aa overlap (4-92:26-122)
10 20 30
pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFS----
::::::::. . : .:: ..: : : .:::
XP_011 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
10 20 30 40 50 60
40 50 60 70 80
pF1KB8 SLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQV--PTQHIPE---VYREAQFYEIKPLV
. . :..::::::: . :: :::::: :: : .:.:: . :::..... ::
XP_011 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLP-DHFPEKGRLKREAEYFQLPDLV
70 80 90 100 110
90 100 110 120 130 140
pF1KB8 KLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQD
:::
XP_011 KLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGRE
120 130 140 150 160 170
>>XP_011535974 (OMIM: 613423) PREDICTED: BTB/POZ domain- (304 aa)
initn: 157 init1: 115 opt: 232 Z-score: 289.7 bits: 61.3 E(85289): 2.1e-09
Smith-Waterman score: 232; 48.0% identity (67.3% similar) in 98 aa overlap (4-92:26-122)
10 20 30
pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFS----
::::::::. . : .:: ..: : : .:::
XP_011 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
10 20 30 40 50 60
40 50 60 70 80
pF1KB8 SLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQV--PTQHIPE---VYREAQFYEIKPLV
. . :..::::::: . :: :::::: :: : .:.:: . :::..... ::
XP_011 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLP-DHFPEKGRLKREAEYFQLPDLV
70 80 90 100 110
90 100 110 120 130 140
pF1KB8 KLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQD
:::
XP_011 KLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGRE
120 130 140 150 160 170
>>XP_006714852 (OMIM: 613423) PREDICTED: BTB/POZ domain- (428 aa)
initn: 157 init1: 115 opt: 232 Z-score: 287.6 bits: 61.4 E(85289): 2.8e-09
Smith-Waterman score: 232; 48.0% identity (67.3% similar) in 98 aa overlap (4-92:26-122)
10 20 30
pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFS----
::::::::. . : .:: ..: : : .:::
XP_006 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
10 20 30 40 50 60
40 50 60 70 80
pF1KB8 SLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQV--PTQHIPE---VYREAQFYEIKPLV
. . :..::::::: . :: :::::: :: : .:.:: . :::..... ::
XP_006 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLP-DHFPEKGRLKREAEYFQLPDLV
70 80 90 100 110
90 100 110 120 130 140
pF1KB8 KLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQD
:::
XP_006 KLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGRE
120 130 140 150 160 170
>>XP_011535973 (OMIM: 613423) PREDICTED: BTB/POZ domain- (428 aa)
initn: 157 init1: 115 opt: 232 Z-score: 287.6 bits: 61.4 E(85289): 2.8e-09
Smith-Waterman score: 232; 48.0% identity (67.3% similar) in 98 aa overlap (4-92:26-122)
10 20 30
pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFS----
::::::::. . : .:: ..: : : .:::
XP_011 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
10 20 30 40 50 60
40 50 60 70 80
pF1KB8 SLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQV--PTQHIPE---VYREAQFYEIKPLV
. . :..::::::: . :: :::::: :: : .:.:: . :::..... ::
XP_011 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLP-DHFPEKGRLKREAEYFQLPDLV
70 80 90 100 110
90 100 110 120 130 140
pF1KB8 KLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQD
:::
XP_011 KLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGRE
120 130 140 150 160 170
>>XP_005268549 (OMIM: 613423) PREDICTED: BTB/POZ domain- (428 aa)
initn: 157 init1: 115 opt: 232 Z-score: 287.6 bits: 61.4 E(85289): 2.8e-09
Smith-Waterman score: 232; 48.0% identity (67.3% similar) in 98 aa overlap (4-92:26-122)
10 20 30
pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFS----
::::::::. . : .:: ..: : : .:::
XP_005 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
10 20 30 40 50 60
40 50 60 70 80
pF1KB8 SLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQV--PTQHIPE---VYREAQFYEIKPLV
. . :..::::::: . :: :::::: :: : .:.:: . :::..... ::
XP_005 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLP-DHFPEKGRLKREAEYFQLPDLV
70 80 90 100 110
90 100 110 120 130 140
pF1KB8 KLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQD
:::
XP_005 KLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGRE
120 130 140 150 160 170
>>XP_005268550 (OMIM: 613423) PREDICTED: BTB/POZ domain- (428 aa)
initn: 157 init1: 115 opt: 232 Z-score: 287.6 bits: 61.4 E(85289): 2.8e-09
Smith-Waterman score: 232; 48.0% identity (67.3% similar) in 98 aa overlap (4-92:26-122)
10 20 30
pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFS----
::::::::. . : .:: ..: : : .:::
XP_005 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
10 20 30 40 50 60
40 50 60 70 80
pF1KB8 SLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQV--PTQHIPE---VYREAQFYEIKPLV
. . :..::::::: . :: :::::: :: : .:.:: . :::..... ::
XP_005 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLP-DHFPEKGRLKREAEYFQLPDLV
70 80 90 100 110
90 100 110 120 130 140
pF1KB8 KLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQD
:::
XP_005 KLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGRE
120 130 140 150 160 170
>>NP_065819 (OMIM: 613423) BTB/POZ domain-containing pro (428 aa)
initn: 157 init1: 115 opt: 232 Z-score: 287.6 bits: 61.4 E(85289): 2.8e-09
Smith-Waterman score: 232; 48.0% identity (67.3% similar) in 98 aa overlap (4-92:26-122)
10 20 30
pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFS----
::::::::. . : .:: ..: : : .:::
NP_065 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
10 20 30 40 50 60
40 50 60 70 80
pF1KB8 SLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQV--PTQHIPE---VYREAQFYEIKPLV
. . :..::::::: . :: :::::: :: : .:.:: . :::..... ::
NP_065 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLP-DHFPEKGRLKREAEYFQLPDLV
70 80 90 100 110
90 100 110 120 130 140
pF1KB8 KLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQD
:::
NP_065 KLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGRE
120 130 140 150 160 170
>>NP_955751 (OMIM: 607947) potassium channel regulatory (229 aa)
initn: 212 init1: 165 opt: 215 Z-score: 270.8 bits: 57.3 E(85289): 2.4e-08
Smith-Waterman score: 215; 41.9% identity (71.0% similar) in 93 aa overlap (4-92:6-98)
10 20 30 40 50
pF1KB8 MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRP
.: :::::.. :: ..:...::.:.::.:... . . :..:.:: . :
NP_955 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 ILDYLRTGQV--PTQHIP--EVYREAQFYEIKPLVKLLEDMPQIFGEQVSRKQFLLQVPG
:::.::: :. ::. .. ::: :::.. :: ::
NP_955 ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPALVEVHFLSRNTQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 YSENLELMVRLARAEAITARKSSVLVCLVETEEQDAYYSEVLCFLQDKKMFKSVVKFGPW
NP_955 AFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPSYHDLVFQC
130 140 150 160 170 180
225 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:24:28 2016 done: Fri Nov 4 15:24:29 2016
Total Scan time: 5.960 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]