Result of FASTA (omim) for
pFN21AB8681
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8681, 377 aa
1>>>pF1KB8681 377 - 377 aa - 377 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5040+/-0.00036; mu= 17.0147+/- 0.022
mean_var=81.8587+/-16.651, 0's: 0 Z-trim(115.8): 28 B-trim: 603 in 1/50
Lambda= 0.141756
statistics sampled from 26439 (26464) to 26439 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.31), width: 16
Scan time: 8.800
The best scores are: opt bits E(85289)
NP_079348 (OMIM: 608152) prostaglandin E synthase ( 377) 2522 525.3 9.2e-149
NP_945176 (OMIM: 608152) prostaglandin E synthase ( 186) 1256 266.1 4.6e-71
NP_001243264 (OMIM: 608152) prostaglandin E syntha ( 186) 1256 266.1 4.6e-71
XP_011517353 (OMIM: 608152) PREDICTED: prostagland ( 186) 1256 266.1 4.6e-71
XP_005252296 (OMIM: 608152) PREDICTED: prostagland ( 186) 1256 266.1 4.6e-71
XP_011517352 (OMIM: 608152) PREDICTED: prostagland ( 186) 1256 266.1 4.6e-71
>>NP_079348 (OMIM: 608152) prostaglandin E synthase 2 is (377 aa)
initn: 2522 init1: 2522 opt: 2522 Z-score: 2791.7 bits: 525.3 E(85289): 9.2e-149
Smith-Waterman score: 2522; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:1-377)
10 20 30 40 50 60
pF1KB8 MDPAARVVRALWPGGCALAWRLGGRPQPLLPTQSRAGFAGAAGGPSPVAAARKGSPRLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MDPAARVVRALWPGGCALAWRLGGRPQPLLPTQSRAGFAGAAGGPSPVAAARKGSPRLLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AAALALGGALGLYHTARWHLRAQDLHAERSAAQLSLSSRLQLTLYQYKTCPFCSKVRAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 AAALALGGALGLYHTARWHLRAQDLHAERSAAQLSLSSRLQLTLYQYKTCPFCSKVRAFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 DFHALPYQVVEVNPVRRAEIKFSSYRKVPILVAQEGESSQQLNDSSVIISALKTYLVSGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DFHALPYQVVEVNPVRRAEIKFSSYRKVPILVAQEGESSQQLNDSSVIISALKTYLVSGQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQVYGGKEARTEEMKWRQWADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 PLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQVYGGKEARTEEMKWRQWADD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 WLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYMGAAAMYLISKRLKSRHRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 WLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYMGAAAMYLISKRLKSRHRLQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 DNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLMQHTHIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLMQHTHIQ
310 320 330 340 350 360
370
pF1KB8 PWYLRVERAITEASPAH
:::::::::::::::::
NP_079 PWYLRVERAITEASPAH
370
>>NP_945176 (OMIM: 608152) prostaglandin E synthase 2 is (186 aa)
initn: 1256 init1: 1256 opt: 1256 Z-score: 1396.7 bits: 266.1 E(85289): 4.6e-71
Smith-Waterman score: 1256; 100.0% identity (100.0% similar) in 186 aa overlap (192-377:1-186)
170 180 190 200 210 220
pF1KB8 LNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
::::::::::::::::::::::::::::::
NP_945 MKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
10 20 30
230 240 250 260 270 280
pF1KB8 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB8 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
100 110 120 130 140 150
350 360 370
pF1KB8 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
::::::::::::::::::::::::::::::::::::
NP_945 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
160 170 180
>>NP_001243264 (OMIM: 608152) prostaglandin E synthase 2 (186 aa)
initn: 1256 init1: 1256 opt: 1256 Z-score: 1396.7 bits: 266.1 E(85289): 4.6e-71
Smith-Waterman score: 1256; 100.0% identity (100.0% similar) in 186 aa overlap (192-377:1-186)
170 180 190 200 210 220
pF1KB8 LNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
::::::::::::::::::::::::::::::
NP_001 MKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
10 20 30
230 240 250 260 270 280
pF1KB8 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB8 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
100 110 120 130 140 150
350 360 370
pF1KB8 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
::::::::::::::::::::::::::::::::::::
NP_001 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
160 170 180
>>XP_011517353 (OMIM: 608152) PREDICTED: prostaglandin E (186 aa)
initn: 1256 init1: 1256 opt: 1256 Z-score: 1396.7 bits: 266.1 E(85289): 4.6e-71
Smith-Waterman score: 1256; 100.0% identity (100.0% similar) in 186 aa overlap (192-377:1-186)
170 180 190 200 210 220
pF1KB8 LNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
::::::::::::::::::::::::::::::
XP_011 MKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
10 20 30
230 240 250 260 270 280
pF1KB8 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB8 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
100 110 120 130 140 150
350 360 370
pF1KB8 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
::::::::::::::::::::::::::::::::::::
XP_011 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
160 170 180
>>XP_005252296 (OMIM: 608152) PREDICTED: prostaglandin E (186 aa)
initn: 1256 init1: 1256 opt: 1256 Z-score: 1396.7 bits: 266.1 E(85289): 4.6e-71
Smith-Waterman score: 1256; 100.0% identity (100.0% similar) in 186 aa overlap (192-377:1-186)
170 180 190 200 210 220
pF1KB8 LNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
::::::::::::::::::::::::::::::
XP_005 MKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
10 20 30
230 240 250 260 270 280
pF1KB8 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB8 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
100 110 120 130 140 150
350 360 370
pF1KB8 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
::::::::::::::::::::::::::::::::::::
XP_005 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
160 170 180
>>XP_011517352 (OMIM: 608152) PREDICTED: prostaglandin E (186 aa)
initn: 1256 init1: 1256 opt: 1256 Z-score: 1396.7 bits: 266.1 E(85289): 4.6e-71
Smith-Waterman score: 1256; 100.0% identity (100.0% similar) in 186 aa overlap (192-377:1-186)
170 180 190 200 210 220
pF1KB8 LNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
::::::::::::::::::::::::::::::
XP_011 MKAVNEQGKEVTEFGNKYWLMLNEKEAQQV
10 20 30
230 240 250 260 270 280
pF1KB8 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYM
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB8 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL
100 110 120 130 140 150
350 360 370
pF1KB8 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
::::::::::::::::::::::::::::::::::::
XP_011 RVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
160 170 180
377 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:31:54 2016 done: Fri Nov 4 14:31:55 2016
Total Scan time: 8.800 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]