Result of FASTA (omim) for
pFN21AB8677
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8677, 368 aa
1>>>pF1KB8677 368 - 368 aa - 368 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9829+/-0.000348; mu= 18.2699+/- 0.022
mean_var=63.1004+/-12.780, 0's: 0 Z-trim(114.2): 15 B-trim: 59 in 1/50
Lambda= 0.161458
statistics sampled from 23863 (23876) to 23863 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.666), E-opt: 0.2 (0.28), width: 16
Scan time: 8.320
The best scores are: opt bits E(85289)
NP_056399 (OMIM: 611519) polymerase delta-interact ( 368) 2540 600.3 2.3e-171
NP_001277074 (OMIM: 611519) polymerase delta-inter ( 350) 1864 442.8 5.6e-124
XP_016873022 (OMIM: 609089) PREDICTED: F-box only ( 309) 197 54.4 4e-07
XP_011518284 (OMIM: 609089) PREDICTED: F-box only ( 317) 197 54.4 4e-07
NP_208385 (OMIM: 609089) F-box only protein 3 isof ( 415) 197 54.5 5e-07
XP_011518283 (OMIM: 609089) PREDICTED: F-box only ( 415) 197 54.5 5e-07
NP_036307 (OMIM: 609089) F-box only protein 3 isof ( 471) 197 54.6 5.6e-07
XP_011518282 (OMIM: 609089) PREDICTED: F-box only ( 479) 197 54.6 5.6e-07
>>NP_056399 (OMIM: 611519) polymerase delta-interacting (368 aa)
initn: 2540 init1: 2540 opt: 2540 Z-score: 3197.4 bits: 600.3 E(85289): 2.3e-171
Smith-Waterman score: 2540; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:1-368)
10 20 30 40 50 60
pF1KB8 MAACTARRALAVGSRWWSRSLTGARWPRPLCAAAGAGAFSPASTTTTRRHLSSRNRPEGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MAACTARRALAVGSRWWSRSLTGARWPRPLCAAAGAGAFSPASTTTTRRHLSSRNRPEGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VLETVGVFEVPKQNGKYETGQLFLHSIFGYRGVVLFPWQARLYDRDVASAAPEKAENPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VLETVGVFEVPKQNGKYETGQLFLHSIFGYRGVVLFPWQARLYDRDVASAAPEKAENPAG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 HGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ILPYTSTDQVPIQHELFERFLLYDQTKAPPFVARETLRAWQEKNHPWLELSDVHRETTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ILPYTSTDQVPIQHELFERFLLYDQTKAPPFVARETLRAWQEKNHPWLELSDVHRETTEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 IRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSDVVQLRERHWRIFSLSGTLETVRGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSDVVQLRERHWRIFSLSGTLETVRGRG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEK
310 320 330 340 350 360
pF1KB8 TPPSGLHW
::::::::
NP_056 TPPSGLHW
>>NP_001277074 (OMIM: 611519) polymerase delta-interacti (350 aa)
initn: 1864 init1: 1864 opt: 1864 Z-score: 2346.7 bits: 442.8 E(85289): 5.6e-124
Smith-Waterman score: 2362; 95.1% identity (95.1% similar) in 368 aa overlap (1-368:1-350)
10 20 30 40 50 60
pF1KB8 MAACTARRALAVGSRWWSRSLTGARWPRPLCAAAGAGAFSPASTTTTRRHLSSRNRPEGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAACTARRALAVGSRWWSRSLTGARWPRPLCAAAGAGAFSPASTTTTRRHLSSRNRPEGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VLETVGVFEVPKQNGKYETGQLFLHSIFGYRGVVLFPWQARLYDRDVASAAPEKAENPAG
::::::::::::::::::::: :::::::::::::::::::::
NP_001 VLETVGVFEVPKQNGKYETGQ------------------ARLYDRDVASAAPEKAENPAG
70 80 90 100
130 140 150 160 170 180
pF1KB8 HGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHED
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 ILPYTSTDQVPIQHELFERFLLYDQTKAPPFVARETLRAWQEKNHPWLELSDVHRETTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILPYTSTDQVPIQHELFERFLLYDQTKAPPFVARETLRAWQEKNHPWLELSDVHRETTEN
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 IRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSDVVQLRERHWRIFSLSGTLETVRGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSDVVQLRERHWRIFSLSGTLETVRGRG
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB8 VVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEK
290 300 310 320 330 340
pF1KB8 TPPSGLHW
::::::::
NP_001 TPPSGLHW
350
>>XP_016873022 (OMIM: 609089) PREDICTED: F-box only prot (309 aa)
initn: 110 init1: 110 opt: 197 Z-score: 249.0 bits: 54.4 E(85289): 4e-07
Smith-Waterman score: 197; 33.3% identity (61.0% similar) in 123 aa overlap (237-353:118-239)
210 220 230 240 250 260
pF1KB8 KAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYC
:: .: :.: .. . . :.. :
XP_016 TSYVKNVVSGGFPIIRDQIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYR
90 100 110 120 130 140
270 280 290 300 310 320
pF1KB8 IRLE----NLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVS
::.: : . :: :.::: . .: .: :.: ::::. :..: . ...:.: ..
XP_016 IRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-VYEYTSCTT
150 160 170 180 190 200
330 340 350 360
pF1KB8 LQASSGHMWG--TFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW
....::.: : ::.: . :.: :: : .
XP_016 FSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLEMGPDEYEEMEEEEE
210 220 230 240 250 260
XP_016 EEEEEDEDDDSADMDESDEDDEEERRRRVFDVPIRRRRCSRLF
270 280 290 300
>>XP_011518284 (OMIM: 609089) PREDICTED: F-box only prot (317 aa)
initn: 110 init1: 110 opt: 197 Z-score: 248.8 bits: 54.4 E(85289): 4e-07
Smith-Waterman score: 197; 33.3% identity (61.0% similar) in 123 aa overlap (237-353:118-239)
210 220 230 240 250 260
pF1KB8 KAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYC
:: .: :.: .. . . :.. :
XP_011 TSYVKNVVSGGFPIIRDQIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYR
90 100 110 120 130 140
270 280 290 300 310 320
pF1KB8 IRLE----NLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVS
::.: : . :: :.::: . .: .: :.: ::::. :..: . ...:.: ..
XP_011 IRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-VYEYTSCTT
150 160 170 180 190 200
330 340 350 360
pF1KB8 LQASSGHMWG--TFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW
....::.: : ::.: . :.: :: : .
XP_011 FSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLPRVLSFSPGTCVFDT
210 220 230 240 250 260
XP_011 LSHHVRSPATMKPSCRRDHVETSHRDRGRHPGAPAVSDSRYLDHPARVPDM
270 280 290 300 310
>>NP_208385 (OMIM: 609089) F-box only protein 3 isoform (415 aa)
initn: 110 init1: 110 opt: 197 Z-score: 247.1 bits: 54.5 E(85289): 5e-07
Smith-Waterman score: 197; 33.3% identity (61.0% similar) in 123 aa overlap (237-353:280-401)
210 220 230 240 250 260
pF1KB8 KAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYC
:: .: :.: .. . . :.. :
NP_208 TSYVKNVVSGGFPIIRDQIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYR
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB8 IRLE----NLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVS
::.: : . :: :.::: . .: .: :.: ::::. :..: . ...:.: ..
NP_208 IRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-VYEYTSCTT
310 320 330 340 350 360
330 340 350 360
pF1KB8 LQASSGHMWG--TFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW
....::.: : ::.: . :.: :: : .
NP_208 FSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLVS
370 380 390 400 410
>>XP_011518283 (OMIM: 609089) PREDICTED: F-box only prot (415 aa)
initn: 110 init1: 110 opt: 197 Z-score: 247.1 bits: 54.5 E(85289): 5e-07
Smith-Waterman score: 197; 33.3% identity (61.0% similar) in 123 aa overlap (237-353:280-401)
210 220 230 240 250 260
pF1KB8 KAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYC
:: .: :.: .. . . :.. :
XP_011 TSYVKNVVSGGFPIIRDQIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYR
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB8 IRLE----NLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVS
::.: : . :: :.::: . .: .: :.: ::::. :..: . ...:.: ..
XP_011 IRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-VYEYTSCTT
310 320 330 340 350 360
330 340 350 360
pF1KB8 LQASSGHMWG--TFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW
....::.: : ::.: . :.: :: : .
XP_011 FSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLFW
370 380 390 400 410
>>NP_036307 (OMIM: 609089) F-box only protein 3 isoform (471 aa)
initn: 110 init1: 110 opt: 197 Z-score: 246.3 bits: 54.6 E(85289): 5.6e-07
Smith-Waterman score: 197; 33.3% identity (61.0% similar) in 123 aa overlap (237-353:280-401)
210 220 230 240 250 260
pF1KB8 KAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYC
:: .: :.: .. . . :.. :
NP_036 TSYVKNVVSGGFPIIRDQIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYR
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB8 IRLE----NLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVS
::.: : . :: :.::: . .: .: :.: ::::. :..: . ...:.: ..
NP_036 IRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-VYEYTSCTT
310 320 330 340 350 360
330 340 350 360
pF1KB8 LQASSGHMWG--TFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW
....::.: : ::.: . :.: :: : .
NP_036 FSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLEMGPDEYEEMEEEEE
370 380 390 400 410 420
NP_036 EEEEEDEDDDSADMDESDEDDEEERRRRVFDVPIRRRRCSRLF
430 440 450 460 470
>>XP_011518282 (OMIM: 609089) PREDICTED: F-box only prot (479 aa)
initn: 110 init1: 110 opt: 197 Z-score: 246.2 bits: 54.6 E(85289): 5.6e-07
Smith-Waterman score: 197; 33.3% identity (61.0% similar) in 123 aa overlap (237-353:280-401)
210 220 230 240 250 260
pF1KB8 KAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYC
:: .: :.: .. . . :.. :
XP_011 TSYVKNVVSGGFPIIRDQIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYR
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB8 IRLE----NLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVS
::.: : . :: :.::: . .: .: :.: ::::. :..: . ...:.: ..
XP_011 IRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-VYEYTSCTT
310 320 330 340 350 360
330 340 350 360
pF1KB8 LQASSGHMWG--TFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW
....::.: : ::.: . :.: :: : .
XP_011 FSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLPRVLSFSPGTCVFDT
370 380 390 400 410 420
XP_011 LSHHVRSPATMKPSCRRDHVETSHRDRGRHPGAPAVSDSRYLDHPARVPDM
430 440 450 460 470
368 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:30:07 2016 done: Fri Nov 4 14:30:09 2016
Total Scan time: 8.320 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]