Result of FASTA (omim) for
pFN21AB8603
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8603, 412 aa
1>>>pF1KB8603 412 - 412 aa - 412 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4347+/-0.000366; mu= 16.3437+/- 0.023
mean_var=68.6798+/-13.378, 0's: 0 Z-trim(112.9): 32 B-trim: 0 in 0/50
Lambda= 0.154760
statistics sampled from 21994 (22022) to 21994 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.258), width: 16
Scan time: 7.530
The best scores are: opt bits E(85289)
NP_001160060 (OMIM: 603896,606273) translation ini ( 412) 2713 614.9 1.1e-175
XP_016858234 (OMIM: 603896,606273) PREDICTED: tran ( 457) 2636 597.8 1.8e-170
NP_001248347 (OMIM: 603896,606273) translation ini ( 401) 2631 596.6 3.5e-170
NP_065098 (OMIM: 603896,606273) translation initia ( 452) 2631 596.7 3.9e-170
XP_016858235 (OMIM: 603896,606273) PREDICTED: tran ( 328) 1790 408.8 1e-113
XP_016858236 (OMIM: 603896,606273) PREDICTED: tran ( 323) 1785 407.7 2.1e-113
NP_068806 (OMIM: 615320,615350,615351,615352) mann ( 360) 164 45.8 0.00021
NP_037466 (OMIM: 615320,615350,615351,615352) mann ( 387) 164 45.8 0.00022
>>NP_001160060 (OMIM: 603896,606273) translation initiat (412 aa)
initn: 2713 init1: 2713 opt: 2713 Z-score: 3275.0 bits: 614.9 E(85289): 1.1e-175
Smith-Waterman score: 2713; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KB8 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP
310 320 330 340 350 360
370 380 390 400 410
pF1KB8 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGYVSPCTHLRQR
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGYVSPCTHLRQR
370 380 390 400 410
>>XP_016858234 (OMIM: 603896,606273) PREDICTED: translat (457 aa)
initn: 2700 init1: 2636 opt: 2636 Z-score: 3181.4 bits: 597.8 E(85289): 1.8e-170
Smith-Waterman score: 2636; 99.5% identity (99.8% similar) in 404 aa overlap (1-404:1-404)
10 20 30 40 50 60
pF1KB8 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP
310 320 330 340 350 360
370 380 390 400 410
pF1KB8 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGYVSPCTHLRQR
::::::::::::::::::::::::::::::::::::::::: .:
XP_016 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGVMSSLESLSTHQKRKEPPH
370 380 390 400 410 420
XP_016 PQLLRSFMALCRIFSKSISEAGARDTVECHFRPVHIA
430 440 450
>>NP_001248347 (OMIM: 603896,606273) translation initiat (401 aa)
initn: 2631 init1: 2631 opt: 2631 Z-score: 3176.3 bits: 596.6 E(85289): 3.5e-170
Smith-Waterman score: 2631; 100.0% identity (100.0% similar) in 401 aa overlap (1-401:1-401)
10 20 30 40 50 60
pF1KB8 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP
310 320 330 340 350 360
370 380 390 400 410
pF1KB8 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGYVSPCTHLRQR
:::::::::::::::::::::::::::::::::::::::::
NP_001 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEG
370 380 390 400
>>NP_065098 (OMIM: 603896,606273) translation initiation (452 aa)
initn: 2631 init1: 2631 opt: 2631 Z-score: 3175.5 bits: 596.7 E(85289): 3.9e-170
Smith-Waterman score: 2631; 100.0% identity (100.0% similar) in 401 aa overlap (1-401:1-401)
10 20 30 40 50 60
pF1KB8 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP
310 320 330 340 350 360
370 380 390 400 410
pF1KB8 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGYVSPCTHLRQR
:::::::::::::::::::::::::::::::::::::::::
NP_065 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGAD
370 380 390 400 410 420
NP_065 IKDCLIGSGQRIEAKAKRVNEVIVGNDQLMEI
430 440 450
>>XP_016858235 (OMIM: 603896,606273) PREDICTED: translat (328 aa)
initn: 1854 init1: 1790 opt: 1790 Z-score: 2162.8 bits: 408.8 E(85289): 1e-113
Smith-Waterman score: 1790; 99.3% identity (99.6% similar) in 275 aa overlap (130-404:1-275)
100 110 120 130 140 150
pF1KB8 DVLVLSCDLITDVALHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIG
::::::::::::::::::::::::::::::
XP_016 MLMRKGQDSIEPVPGQKGKKKAVEQRDFIG
10 20 30
160 170 180 190 200 210
pF1KB8 VDSTGKRLLFMANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDSTGKRLLFMANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENG
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB8 SITSIRSELIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SITSIRSELIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYD
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB8 ACWNACRGDRWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACWNACRGDRWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPP
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB8 VHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVE
220 230 240 250 260 270
400 410
pF1KB8 EGYVSPCTHLRQR
:: .:
XP_016 EGVMSSLESLSTHQKRKEPPHPQLLRSFMALCRIFSKSISEAGARDTVECHFRPVHIA
280 290 300 310 320
>>XP_016858236 (OMIM: 603896,606273) PREDICTED: translat (323 aa)
initn: 1785 init1: 1785 opt: 1785 Z-score: 2156.8 bits: 407.7 E(85289): 2.1e-113
Smith-Waterman score: 1785; 100.0% identity (100.0% similar) in 272 aa overlap (130-401:1-272)
100 110 120 130 140 150
pF1KB8 DVLVLSCDLITDVALHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIG
::::::::::::::::::::::::::::::
XP_016 MLMRKGQDSIEPVPGQKGKKKAVEQRDFIG
10 20 30
160 170 180 190 200 210
pF1KB8 VDSTGKRLLFMANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDSTGKRLLFMANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENG
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB8 SITSIRSELIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SITSIRSELIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYD
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB8 ACWNACRGDRWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACWNACRGDRWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPP
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB8 VHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVE
220 230 240 250 260 270
400 410
pF1KB8 EGYVSPCTHLRQR
::
XP_016 EGSNIQGSVICNNAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVGNDQLMEI
280 290 300 310 320
>>NP_068806 (OMIM: 615320,615350,615351,615352) mannose- (360 aa)
initn: 111 init1: 87 opt: 164 Z-score: 200.1 bits: 45.8 E(85289): 0.00021
Smith-Waterman score: 164; 26.3% identity (59.1% similar) in 137 aa overlap (4-134:2-137)
10 20 30 40 50 60
pF1KB8 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ
.:.... : :.:. :: : ::::. :::.. . .. : .: ..::.... ..
NP_068 MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSY-MS
10 20 30 40 50
70 80 90 100 110
pF1KB8 KALCAEFK---MKMKPDIVCIPDDADMGTADSL---RYIYPKLKTDVLVLSCDLITDVAL
..: :.: ... : .. .::: : : . . .::. :.: : .
NP_068 QVLEKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 HEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEA
. .:.. : . ..:. :
NP_068 QAMVQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMYI
120 130 140 150 160 170
>>NP_037466 (OMIM: 615320,615350,615351,615352) mannose- (387 aa)
initn: 111 init1: 87 opt: 164 Z-score: 199.7 bits: 45.8 E(85289): 0.00022
Smith-Waterman score: 164; 26.3% identity (59.1% similar) in 137 aa overlap (4-134:2-137)
10 20 30 40 50 60
pF1KB8 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ
.:.... : :.:. :: : ::::. :::.. . .. : .: ..::.... ..
NP_037 MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSY-MS
10 20 30 40 50
70 80 90 100 110
pF1KB8 KALCAEFK---MKMKPDIVCIPDDADMGTADSL---RYIYPKLKTDVLVLSCDLITDVAL
..: :.: ... : .. .::: : : . . .::. :.: : .
NP_037 QVLEKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 HEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEA
. .:.. : . ..:. :
NP_037 QAMVQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMYI
120 130 140 150 160 170
412 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 13:40:10 2016 done: Fri Nov 4 13:40:11 2016
Total Scan time: 7.530 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]