Result of FASTA (omim) for
pFN21AB8397
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8397, 462 aa
1>>>pF1KB8397 462 - 462 aa - 462 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6051+/-0.00064; mu= -3.5607+/- 0.037
mean_var=675.2041+/-159.916, 0's: 0 Z-trim(114.0): 1929 B-trim: 0 in 0/55
Lambda= 0.049358
statistics sampled from 21170 (23636) to 21170 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.626), E-opt: 0.2 (0.277), width: 16
Scan time: 7.910
The best scores are: opt bits E(85289)
NP_859029 (OMIM: 611223,615937) RAC-gamma serine/t ( 465) 3131 239.4 1.6e-62
NP_001193658 (OMIM: 611223,615937) RAC-gamma serin ( 465) 3131 239.4 1.6e-62
XP_005273051 (OMIM: 611223,615937) PREDICTED: RAC- ( 479) 3049 233.6 9.1e-61
NP_005456 (OMIM: 611223,615937) RAC-gamma serine/t ( 479) 3049 233.6 9.1e-61
XP_005273052 (OMIM: 611223,615937) PREDICTED: RAC- ( 479) 3049 233.6 9.1e-61
XP_011542314 (OMIM: 611223,615937) PREDICTED: RAC- ( 435) 2855 219.7 1.3e-56
XP_016855474 (OMIM: 611223,615937) PREDICTED: RAC- ( 418) 2621 203.0 1.3e-51
XP_005267458 (OMIM: 114480,114500,164730,167000,17 ( 480) 2574 199.8 1.4e-50
NP_005154 (OMIM: 114480,114500,164730,167000,17692 ( 480) 2574 199.8 1.4e-50
NP_001014431 (OMIM: 114480,114500,164730,167000,17 ( 480) 2574 199.8 1.4e-50
NP_001014432 (OMIM: 114480,114500,164730,167000,17 ( 480) 2574 199.8 1.4e-50
XP_011524920 (OMIM: 125853,164731,240900) PREDICTE ( 481) 2474 192.6 1.9e-48
NP_001617 (OMIM: 125853,164731,240900) RAC-beta se ( 481) 2474 192.6 1.9e-48
XP_011524922 (OMIM: 125853,164731,240900) PREDICTE ( 481) 2474 192.6 1.9e-48
XP_011524918 (OMIM: 125853,164731,240900) PREDICTE ( 481) 2474 192.6 1.9e-48
XP_011524917 (OMIM: 125853,164731,240900) PREDICTE ( 481) 2474 192.6 1.9e-48
XP_011524921 (OMIM: 125853,164731,240900) PREDICTE ( 481) 2474 192.6 1.9e-48
XP_011524916 (OMIM: 125853,164731,240900) PREDICTE ( 481) 2474 192.6 1.9e-48
XP_016881959 (OMIM: 125853,164731,240900) PREDICTE ( 481) 2474 192.6 1.9e-48
XP_016876567 (OMIM: 114480,114500,164730,167000,17 ( 530) 2366 185.0 4.2e-46
XP_016876566 (OMIM: 114480,114500,164730,167000,17 ( 530) 2366 185.0 4.2e-46
XP_016876565 (OMIM: 114480,114500,164730,167000,17 ( 530) 2366 185.0 4.2e-46
XP_016876564 (OMIM: 114480,114500,164730,167000,17 ( 530) 2366 185.0 4.2e-46
NP_001229956 (OMIM: 125853,164731,240900) RAC-beta ( 419) 2145 169.1 2e-41
NP_001229957 (OMIM: 125853,164731,240900) RAC-beta ( 419) 2145 169.1 2e-41
XP_011524924 (OMIM: 125853,164731,240900) PREDICTE ( 400) 2111 166.7 1.1e-40
XP_011542315 (OMIM: 611223,615937) PREDICTED: RAC- ( 295) 1820 145.7 1.6e-34
XP_006711789 (OMIM: 611223,615937) PREDICTED: RAC- ( 247) 1561 127.1 5.2e-29
XP_011542316 (OMIM: 611223,615937) PREDICTED: RAC- ( 249) 1237 104.1 4.6e-22
NP_005618 (OMIM: 602958) serine/threonine-protein ( 431) 1161 99.1 2.6e-20
NP_001137150 (OMIM: 602958) serine/threonine-prote ( 445) 1161 99.1 2.6e-20
NP_001137149 (OMIM: 602958) serine/threonine-prote ( 459) 1161 99.1 2.6e-20
NP_001137148 (OMIM: 602958) serine/threonine-prote ( 526) 1161 99.2 2.8e-20
XP_011534373 (OMIM: 602958) PREDICTED: serine/thre ( 526) 1161 99.2 2.8e-20
NP_057360 (OMIM: 607589) serine/threonine-protein ( 427) 1140 97.6 7.2e-20
NP_733794 (OMIM: 607589) serine/threonine-protein ( 367) 1134 97.0 9e-20
NP_001186193 (OMIM: 607589) serine/threonine-prote ( 367) 1134 97.0 9e-20
XP_011531285 (OMIM: 176975) PREDICTED: protein kin ( 436) 1117 95.9 2.3e-19
XP_006712113 (OMIM: 176975) PREDICTED: protein kin ( 460) 1117 96.0 2.3e-19
XP_011531284 (OMIM: 176975) PREDICTED: protein kin ( 497) 1117 96.0 2.4e-19
XP_011531282 (OMIM: 176975) PREDICTED: protein kin ( 587) 1117 96.2 2.6e-19
XP_011531283 (OMIM: 176975) PREDICTED: protein kin ( 587) 1117 96.2 2.6e-19
XP_016859978 (OMIM: 176975) PREDICTED: protein kin ( 587) 1117 96.2 2.6e-19
XP_016859979 (OMIM: 176975) PREDICTED: protein kin ( 587) 1117 96.2 2.6e-19
XP_016859980 (OMIM: 176975) PREDICTED: protein kin ( 587) 1117 96.2 2.6e-19
XP_011531280 (OMIM: 176975) PREDICTED: protein kin ( 623) 1117 96.2 2.7e-19
XP_016859977 (OMIM: 176975) PREDICTED: protein kin ( 623) 1117 96.2 2.7e-19
XP_016859976 (OMIM: 176975) PREDICTED: protein kin ( 623) 1117 96.2 2.7e-19
XP_011531277 (OMIM: 176975) PREDICTED: protein kin ( 641) 1117 96.2 2.7e-19
XP_016859975 (OMIM: 176975) PREDICTED: protein kin ( 641) 1117 96.2 2.7e-19
>>NP_859029 (OMIM: 611223,615937) RAC-gamma serine/threo (465 aa)
initn: 3131 init1: 3131 opt: 3131 Z-score: 1243.6 bits: 239.4 E(85289): 1.6e-62
Smith-Waterman score: 3131; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
370 380 390 400 410 420
430 440 450 460
pF1KB8 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGN
::::::::::::::::::::::::::::::::::::::::::
NP_859 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGNWKK
430 440 450 460
>>NP_001193658 (OMIM: 611223,615937) RAC-gamma serine/th (465 aa)
initn: 3131 init1: 3131 opt: 3131 Z-score: 1243.6 bits: 239.4 E(85289): 1.6e-62
Smith-Waterman score: 3131; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
370 380 390 400 410 420
430 440 450 460
pF1KB8 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGN
::::::::::::::::::::::::::::::::::::::::::
NP_001 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGNWKK
430 440 450 460
>>XP_005273051 (OMIM: 611223,615937) PREDICTED: RAC-gamm (479 aa)
initn: 3043 init1: 3043 opt: 3049 Z-score: 1211.9 bits: 233.6 E(85289): 9.1e-61
Smith-Waterman score: 3049; 98.7% identity (99.3% similar) in 459 aa overlap (1-457:1-459)
10 20 30 40 50 60
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
370 380 390 400 410 420
430 440 450 460
pF1KB8 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQS--DCGMLGN
::::::::::::::::::::::::::::::: ... ::
XP_005 PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
430 440 450 460 470
>>NP_005456 (OMIM: 611223,615937) RAC-gamma serine/threo (479 aa)
initn: 3043 init1: 3043 opt: 3049 Z-score: 1211.9 bits: 233.6 E(85289): 9.1e-61
Smith-Waterman score: 3049; 98.7% identity (99.3% similar) in 459 aa overlap (1-457:1-459)
10 20 30 40 50 60
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
370 380 390 400 410 420
430 440 450 460
pF1KB8 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQS--DCGMLGN
::::::::::::::::::::::::::::::: ... ::
NP_005 PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
430 440 450 460 470
>>XP_005273052 (OMIM: 611223,615937) PREDICTED: RAC-gamm (479 aa)
initn: 3043 init1: 3043 opt: 3049 Z-score: 1211.9 bits: 233.6 E(85289): 9.1e-61
Smith-Waterman score: 3049; 98.7% identity (99.3% similar) in 459 aa overlap (1-457:1-459)
10 20 30 40 50 60
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
370 380 390 400 410 420
430 440 450 460
pF1KB8 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQS--DCGMLGN
::::::::::::::::::::::::::::::: ... ::
XP_005 PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
430 440 450 460 470
>>XP_011542314 (OMIM: 611223,615937) PREDICTED: RAC-gamm (435 aa)
initn: 2854 init1: 2854 opt: 2855 Z-score: 1137.6 bits: 219.7 E(85289): 1.3e-56
Smith-Waterman score: 2855; 97.0% identity (97.7% similar) in 439 aa overlap (1-439:1-435)
10 20 30 40 50 60
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
370 380 390 400 410 420
430 440 450 460
pF1KB8 PFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGN
:. .: : ::. :
XP_011 LFRERVISLP----FDNAF
430
>>XP_016855474 (OMIM: 611223,615937) PREDICTED: RAC-gamm (418 aa)
initn: 2615 init1: 2615 opt: 2621 Z-score: 1047.7 bits: 203.0 E(85289): 1.3e-51
Smith-Waterman score: 2621; 98.5% identity (99.2% similar) in 398 aa overlap (62-457:1-398)
40 50 60 70 80 90
pF1KB8 DGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDT
::::::::::::::::::::::::::::::
XP_016 MKTERPKPNTFIIRCLQWTTVIERTFHVDT
10 20 30
100 110 120 130 140 150
pF1KB8 PEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYL
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB8 KLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSL
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB8 KYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRD
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB8 LKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWG
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB8 LGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGG
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB8 GPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEK
340 350 360 370 380 390
460
pF1KB8 CQQS--DCGMLGN
... ::
XP_016 YDEDGMDCMDNERRPHFPQFSYSASGRE
400 410
>>XP_005267458 (OMIM: 114480,114500,164730,167000,176920 (480 aa)
initn: 2126 init1: 1127 opt: 2574 Z-score: 1029.1 bits: 199.8 E(85289): 1.4e-50
Smith-Waterman score: 2574; 82.4% identity (93.3% similar) in 460 aa overlap (1-457:1-460)
10 20 30 40 50
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDL-PYPLNNFSVAKC
::::.::::::..:::::::.:::::::::.::.::::::.::::: ::::::::.:
XP_005 MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 QLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNC
::::::::.:::::::::::::::::::::.::::::::: :::.::: :..::::.:.
XP_005 QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 SPTSQIDNIGEEEMDASTTHHK-RKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKI
: :: : :::..: .. : : :::.:.::::::::::::::::.:::.:.::::::
XP_005 RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 LKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLS
::::::.:::::::::::.:::.:.::::::.:::::::.:::::::::.::::::::::
XP_005 LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 RERVFSEDRTRFYGAEIVSALDYLHSGK-IVYRDLKLENLMLDKDGHIKITDFGLCKEGI
:::::::::.:::::::::::::::: : .::::::::::::::::::::::::::::::
XP_005 RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 TDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
:.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 ILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKK
::::.:.:::::. .::::::::: :::..::::: .::::::.: ::.:. :: ::.::
XP_005 ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKK
370 380 390 400 410 420
420 430 440 450 460
pF1KB8 LVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGN
: ::::::::::::::::::::::: ::::::.. .. .:
XP_005 LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
430 440 450 460 470 480
>>NP_005154 (OMIM: 114480,114500,164730,167000,176920,18 (480 aa)
initn: 2126 init1: 1127 opt: 2574 Z-score: 1029.1 bits: 199.8 E(85289): 1.4e-50
Smith-Waterman score: 2574; 82.4% identity (93.3% similar) in 460 aa overlap (1-457:1-460)
10 20 30 40 50
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDL-PYPLNNFSVAKC
::::.::::::..:::::::.:::::::::.::.::::::.::::: ::::::::.:
NP_005 MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 QLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNC
::::::::.:::::::::::::::::::::.::::::::: :::.::: :..::::.:.
NP_005 QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 SPTSQIDNIGEEEMDASTTHHK-RKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKI
: :: : :::..: .. : : :::.:.::::::::::::::::.:::.:.::::::
NP_005 RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 LKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLS
::::::.:::::::::::.:::.:.::::::.:::::::.:::::::::.::::::::::
NP_005 LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 RERVFSEDRTRFYGAEIVSALDYLHSGK-IVYRDLKLENLMLDKDGHIKITDFGLCKEGI
:::::::::.:::::::::::::::: : .::::::::::::::::::::::::::::::
NP_005 RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 TDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
:.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 ILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKK
::::.:.:::::. .::::::::: :::..::::: .::::::.: ::.:. :: ::.::
NP_005 ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKK
370 380 390 400 410 420
420 430 440 450 460
pF1KB8 LVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGN
: ::::::::::::::::::::::: ::::::.. .. .:
NP_005 LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
430 440 450 460 470 480
>>NP_001014431 (OMIM: 114480,114500,164730,167000,176920 (480 aa)
initn: 2126 init1: 1127 opt: 2574 Z-score: 1029.1 bits: 199.8 E(85289): 1.4e-50
Smith-Waterman score: 2574; 82.4% identity (93.3% similar) in 460 aa overlap (1-457:1-460)
10 20 30 40 50
pF1KB8 MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDL-PYPLNNFSVAKC
::::.::::::..:::::::.:::::::::.::.::::::.::::: ::::::::.:
NP_001 MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 QLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNC
::::::::.:::::::::::::::::::::.::::::::: :::.::: :..::::.:.
NP_001 QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 SPTSQIDNIGEEEMDASTTHHK-RKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKI
: :: : :::..: .. : : :::.:.::::::::::::::::.:::.:.::::::
NP_001 RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 LKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLS
::::::.:::::::::::.:::.:.::::::.:::::::.:::::::::.::::::::::
NP_001 LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 RERVFSEDRTRFYGAEIVSALDYLHSGK-IVYRDLKLENLMLDKDGHIKITDFGLCKEGI
:::::::::.:::::::::::::::: : .::::::::::::::::::::::::::::::
NP_001 RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 TDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
:.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 ILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKK
::::.:.:::::. .::::::::: :::..::::: .::::::.: ::.:. :: ::.::
NP_001 ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKK
370 380 390 400 410 420
420 430 440 450 460
pF1KB8 LVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKCQQSDCGMLGN
: ::::::::::::::::::::::: ::::::.. .. .:
NP_001 LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
430 440 450 460 470 480
462 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:33:51 2016 done: Fri Nov 4 12:33:52 2016
Total Scan time: 7.910 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]