Result of FASTA (omim) for
pFN21AB8390
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8390, 398 aa
1>>>pF1KB8390 398 - 398 aa - 398 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.6566+/-0.000443; mu= -16.8385+/- 0.028
mean_var=845.7837+/-192.197, 0's: 0 Z-trim(125.9): 386 B-trim: 2681 in 1/61
Lambda= 0.044101
statistics sampled from 49746 (50745) to 49746 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.842), E-opt: 0.2 (0.595), width: 16
Scan time: 8.730
The best scores are: opt bits E(85289)
NP_001003845 (OMIM: 609391) transcription factor S ( 398) 2847 195.9 1.5e-49
XP_005246599 (OMIM: 609391) PREDICTED: transcripti ( 442) 2755 190.1 9.1e-48
XP_011509461 (OMIM: 609391) PREDICTED: transcripti ( 454) 2746 189.5 1.4e-47
NP_001313472 (OMIM: 600540) transcription factor S ( 471) 746 62.3 2.8e-09
XP_005249885 (OMIM: 600540) PREDICTED: transcripti ( 767) 746 62.6 3.8e-09
NP_001313471 (OMIM: 600540) transcription factor S ( 767) 746 62.6 3.8e-09
NP_003103 (OMIM: 600540) transcription factor Sp4 ( 784) 746 62.6 3.9e-09
NP_001017371 (OMIM: 601804) transcription factor S ( 713) 700 59.6 2.8e-08
NP_001166183 (OMIM: 601804) transcription factor S ( 778) 700 59.6 2.9e-08
NP_003102 (OMIM: 601804) transcription factor Sp3 ( 781) 700 59.6 2.9e-08
NP_001238754 (OMIM: 189906) transcription factor S ( 737) 693 59.2 3.9e-08
XP_011536998 (OMIM: 189906) PREDICTED: transcripti ( 778) 693 59.2 4e-08
NP_003100 (OMIM: 189906) transcription factor Sp1 ( 778) 693 59.2 4e-08
NP_612482 (OMIM: 189906) transcription factor Sp1 ( 785) 693 59.2 4e-08
NP_945194 (OMIM: 608306) transcription factor Sp8 ( 490) 653 56.4 1.8e-07
NP_001245177 (OMIM: 608613) transcription factor S ( 376) 649 56.0 1.8e-07
XP_006722178 (OMIM: 608613) PREDICTED: transcripti ( 376) 649 56.0 1.8e-07
NP_954871 (OMIM: 608613) transcription factor Sp6 ( 376) 649 56.0 1.8e-07
NP_874359 (OMIM: 608306) transcription factor Sp8 ( 508) 653 56.4 1.8e-07
NP_001287766 (OMIM: 606633,613849) transcription f ( 413) 605 53.2 1.3e-06
XP_011536202 (OMIM: 606633,613849) PREDICTED: tran ( 413) 605 53.2 1.3e-06
NP_001166938 (OMIM: 606633,613849) transcription f ( 431) 605 53.3 1.4e-06
NP_690599 (OMIM: 606633,613849) transcription fact ( 431) 605 53.3 1.4e-06
NP_003101 (OMIM: 601801) transcription factor Sp2 ( 613) 569 51.2 8.2e-06
XP_006722090 (OMIM: 601801) PREDICTED: transcripti ( 660) 569 51.2 8.6e-06
XP_011523444 (OMIM: 601801) PREDICTED: transcripti ( 660) 569 51.2 8.6e-06
XP_016880458 (OMIM: 601801) PREDICTED: transcripti ( 660) 569 51.2 8.6e-06
XP_016880457 (OMIM: 601801) PREDICTED: transcripti ( 660) 569 51.2 8.6e-06
XP_006722088 (OMIM: 601801) PREDICTED: transcripti ( 660) 569 51.2 8.6e-06
XP_006722089 (OMIM: 601801) PREDICTED: transcripti ( 660) 569 51.2 8.6e-06
XP_011523445 (OMIM: 601801) PREDICTED: transcripti ( 660) 569 51.2 8.6e-06
XP_006722086 (OMIM: 601801) PREDICTED: transcripti ( 667) 569 51.2 8.6e-06
XP_011523442 (OMIM: 601801) PREDICTED: transcripti ( 717) 569 51.3 9e-06
XP_011523441 (OMIM: 601801) PREDICTED: transcripti ( 727) 569 51.3 9.1e-06
XP_011523440 (OMIM: 601801) PREDICTED: transcripti ( 760) 569 51.3 9.3e-06
XP_011523439 (OMIM: 601801) PREDICTED: transcripti ( 768) 569 51.3 9.4e-06
XP_011523438 (OMIM: 601801) PREDICTED: transcripti ( 771) 569 51.3 9.4e-06
XP_011513788 (OMIM: 600540) PREDICTED: transcripti ( 711) 565 51.0 1.1e-05
XP_005249886 (OMIM: 600540) PREDICTED: transcripti ( 706) 541 49.5 3.1e-05
NP_619638 (OMIM: 609393) Krueppel-like factor 14 [ ( 323) 514 47.3 6.3e-05
NP_114124 (OMIM: 606139) Krueppel-like factor 16 [ ( 252) 501 46.3 9.6e-05
NP_057079 (OMIM: 605328,612001) Krueppel-like fact ( 288) 477 44.9 0.0003
NP_001171189 (OMIM: 603301,610508) Krueppel-like f ( 495) 476 45.1 0.00043
NP_001171187 (OMIM: 603301,610508) Krueppel-like f ( 495) 476 45.1 0.00043
NP_003588 (OMIM: 603301,610508) Krueppel-like fact ( 512) 476 45.2 0.00044
NP_001027453 (OMIM: 601878) Krueppel-like factor 1 ( 469) 465 44.4 0.00068
NP_001197 (OMIM: 602902) Krueppel-like factor 9 [H ( 244) 456 43.5 0.00069
NP_005646 (OMIM: 601878) Krueppel-like factor 10 i ( 480) 465 44.4 0.00069
XP_011525944 (OMIM: 111150,600599,613566,613673) P ( 324) 452 43.4 0.00097
NP_006554 (OMIM: 111150,600599,613566,613673) Krue ( 362) 452 43.4 0.001
>>NP_001003845 (OMIM: 609391) transcription factor Sp5 [ (398 aa)
initn: 2847 init1: 2847 opt: 2847 Z-score: 1010.7 bits: 195.9 E(85289): 1.5e-49
Smith-Waterman score: 2847; 100.0% identity (100.0% similar) in 398 aa overlap (1-398:1-398)
10 20 30 40 50 60
pF1KB8 MAAVAVLRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGAAAPPDFLQVPYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVAVLRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGAAAPPDFLQVPYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PALGSPSRLFHPWTADMPAHSPGALPPPHPSLGLTPQKTHLQPSFGAAHELPLTPPADPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PALGSPSRLFHPWTADMPAHSPGALPPPHPSLGLTPQKTHLQPSFGAAHELPLTPPADPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPPPPPPPPTCRQLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPPPPPPPPTCRQLSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 NPAPDDLPWWSIPQAGAGPGASGVPGSGLSGACAGAPHAPRFPASAAAAAAAAAALQRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPAPDDLPWWSIPQAGAGPGASGVPGSGLSGACAGAPHAPRFPASAAAAAAAAAALQRGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCRCPNCQAAGGAPEAEPGKKKQHVCHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCRCPNCQAAGGAPEAEPGKKKQHVCHV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 PGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFACPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFACPE
310 320 330 340 350 360
370 380 390
pF1KB8 CGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDARDL
::::::::::::::::::::::::::::::::::::::
NP_001 CGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDARDL
370 380 390
>>XP_005246599 (OMIM: 609391) PREDICTED: transcription f (442 aa)
initn: 2754 init1: 2754 opt: 2755 Z-score: 978.5 bits: 190.1 E(85289): 9.1e-48
Smith-Waterman score: 2755; 96.5% identity (98.0% similar) in 398 aa overlap (1-398:45-442)
10 20 30
pF1KB8 MAAVAVLRNDSLQAFLQDRTPSASPDLGKH
..: . : .. .::::::::::::::
XP_005 PTLTDHGAGRGPSDASPSHFAPASSKAGWRLSAPSSLARSARGPHVQDRTPSASPDLGKH
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB8 SPLALLAATCSRIGQPGAAAPPDFLQVPYDPALGSPSRLFHPWTADMPAHSPGALPPPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPLALLAATCSRIGQPGAAAPPDFLQVPYDPALGSPSRLFHPWTADMPAHSPGALPPPHP
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB8 SLGLTPQKTHLQPSFGAAHELPLTPPADPSYPYEFSPVKMLPSSMAALPASCAPAYVPYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLGLTPQKTHLQPSFGAAHELPLTPPADPSYPYEFSPVKMLPSSMAALPASCAPAYVPYA
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB8 AQAALPPGYSNLLPPPPPPPPPPTCRQLSPNPAPDDLPWWSIPQAGAGPGASGVPGSGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQAALPPGYSNLLPPPPPPPPPPTCRQLSPNPAPDDLPWWSIPQAGAGPGASGVPGSGLS
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB8 GACAGAPHAPRFPASAAAAAAAAAALQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GACAGAPHAPRFPASAAAAAAAAAALQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARR
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB8 CRRCRCPNCQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CRRCRCPNCQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNW
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB8 LFCGKSFTRSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFCGKSFTRSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGV
380 390 400 410 420 430
pF1KB8 KREDARDL
::::::::
XP_005 KREDARDL
440
>>XP_011509461 (OMIM: 609391) PREDICTED: transcription f (454 aa)
initn: 2746 init1: 2746 opt: 2746 Z-score: 975.3 bits: 189.5 E(85289): 1.4e-47
Smith-Waterman score: 2746; 100.0% identity (100.0% similar) in 381 aa overlap (18-398:74-454)
10 20 30 40
pF1KB8 MAAVAVLRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPG
::::::::::::::::::::::::::::::
XP_011 RLSAPSSLARSARGPHVQVAQAPKVSLGRWDRTPSASPDLGKHSPLALLAATCSRIGQPG
50 60 70 80 90 100
50 60 70 80 90 100
pF1KB8 AAAPPDFLQVPYDPALGSPSRLFHPWTADMPAHSPGALPPPHPSLGLTPQKTHLQPSFGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAAPPDFLQVPYDPALGSPSRLFHPWTADMPAHSPGALPPPHPSLGLTPQKTHLQPSFGA
110 120 130 140 150 160
110 120 130 140 150 160
pF1KB8 AHELPLTPPADPSYPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHELPLTPPADPSYPYEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPP
170 180 190 200 210 220
170 180 190 200 210 220
pF1KB8 PPPPPPTCRQLSPNPAPDDLPWWSIPQAGAGPGASGVPGSGLSGACAGAPHAPRFPASAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPPPPTCRQLSPNPAPDDLPWWSIPQAGAGPGASGVPGSGLSGACAGAPHAPRFPASAA
230 240 250 260 270 280
230 240 250 260 270 280
pF1KB8 AAAAAAAALQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCRCPNCQAAGGAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAAAAAAALQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCRCPNCQAAGGAPE
290 300 310 320 330 340
290 300 310 320 330 340
pF1KB8 AEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHL
350 360 370 380 390 400
350 360 370 380 390
pF1KB8 RTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDARDL
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDARDL
410 420 430 440 450
>>NP_001313472 (OMIM: 600540) transcription factor Sp4 i (471 aa)
initn: 705 init1: 705 opt: 746 Z-score: 287.4 bits: 62.3 E(85289): 2.8e-09
Smith-Waterman score: 758; 38.8% identity (59.9% similar) in 374 aa overlap (37-382:53-420)
10 20 30 40 50 60
pF1KB8 LRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGAAAPPDFLQVPYDPA--LG
::: :. .: .. :. .: : . :
NP_001 DTLVSSADTGQYASTSASSSERTIEESQTPAATESE-AQSSSQLQPNGMQNAQDQSNSLQ
30 40 50 60 70 80
70 80 90 100 110
pF1KB8 SPSRLFHPWTADMPAHSPG-----ALPPPHPSL--GLTPQKTHLQP-------SFGAAHE
. . . .: .. ..: :.:: .: : : : . :: . . ..
NP_001 QVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQV
90 100 110 120 130 140
120 130 140 150 160
pF1KB8 LPLTPPADPSYPYEFSPVKMLP-SSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPP--
: .: :: .. :.. .:.. : .. : . . : ..: :
NP_001 LIRAPTLTPSGQISWQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVA
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB8 --PPPPPPTCRQLSPNPAPDDLPWWSIPQAGA-GPGASGVPGS--GLSGACAGAPHAPRF
: . ::. : .: :. . :: : ..::: . ...: : .
NP_001 VAGAPITLNTAQLASVP---NLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQ
210 220 230 240 250
230 240 250 260 270
pF1KB8 PASAAAAAAAAAALQRGLV--LGPSDFAQYQSQIAALLQTKAPLAATARRCRR--CRCPN
:. : ...:.... . . ..:....: . : . ::. . ..: :: : :::
NP_001 QATIAPVTVAVGGIANATIGAVSPDQLTQVHLQQGQ--QTSDQEVQPGKRLRRVACSCPN
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB8 CQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFT
:. . : ::::::::.::. ::::::::::::.::::::::::::.:::.:::: ::
NP_001 CREGEGRGSNEPGKKKQHICHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFT
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB8 RSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDARDL
:::::::: ::::::::: ::::.:::::::::.::::::::::
NP_001 RSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDS
380 390 400 410 420 430
NP_001 SVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF
440 450 460 470
>>XP_005249885 (OMIM: 600540) PREDICTED: transcription f (767 aa)
initn: 812 init1: 705 opt: 746 Z-score: 285.2 bits: 62.6 E(85289): 3.8e-09
Smith-Waterman score: 758; 38.8% identity (59.9% similar) in 374 aa overlap (37-382:349-716)
10 20 30 40 50 60
pF1KB8 LRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGAAAPPDFLQVPYDPA--LG
::: :. .: .. :. .: : . :
XP_005 DTLVSSADTGQYASTSASSSERTIEESQTPAATESE-AQSSSQLQPNGMQNAQDQSNSLQ
320 330 340 350 360 370
70 80 90 100 110
pF1KB8 SPSRLFHPWTADMPAHSPG-----ALPPPHPSL--GLTPQKTHLQP-------SFGAAHE
. . . .: .. ..: :.:: .: : : : . :: . . ..
XP_005 QVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQV
380 390 400 410 420 430
120 130 140 150 160
pF1KB8 LPLTPPADPSYPYEFSPVKMLP-SSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPP--
: .: :: .. :.. .:.. : .. : . . : ..: :
XP_005 LIRAPTLTPSGQISWQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVA
440 450 460 470 480 490
170 180 190 200 210 220
pF1KB8 --PPPPPPTCRQLSPNPAPDDLPWWSIPQAGA-GPGASGVPGS--GLSGACAGAPHAPRF
: . ::. : .: :. . :: : ..::: . ...: : .
XP_005 VAGAPITLNTAQLASVP---NLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQ
500 510 520 530 540 550
230 240 250 260 270
pF1KB8 PASAAAAAAAAAALQRGLV--LGPSDFAQYQSQIAALLQTKAPLAATARRCRR--CRCPN
:. : ...:.... . . ..:....: . : . ::. . ..: :: : :::
XP_005 QATIAPVTVAVGGIANATIGAVSPDQLTQVHLQQGQ--QTSDQEVQPGKRLRRVACSCPN
560 570 580 590 600 610
280 290 300 310 320 330
pF1KB8 CQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFT
:. . : ::::::::.::. ::::::::::::.::::::::::::.:::.:::: ::
XP_005 CREGEGRGSNEPGKKKQHICHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFT
620 630 640 650 660 670
340 350 360 370 380 390
pF1KB8 RSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDARDL
:::::::: ::::::::: ::::.:::::::::.::::::::::
XP_005 RSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDS
680 690 700 710 720 730
XP_005 SVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF
740 750 760
>>NP_001313471 (OMIM: 600540) transcription factor Sp4 i (767 aa)
initn: 812 init1: 705 opt: 746 Z-score: 285.2 bits: 62.6 E(85289): 3.8e-09
Smith-Waterman score: 758; 38.8% identity (59.9% similar) in 374 aa overlap (37-382:349-716)
10 20 30 40 50 60
pF1KB8 LRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGAAAPPDFLQVPYDPA--LG
::: :. .: .. :. .: : . :
NP_001 DTLVSSADTGQYASTSASSSERTIEESQTPAATESE-AQSSSQLQPNGMQNAQDQSNSLQ
320 330 340 350 360 370
70 80 90 100 110
pF1KB8 SPSRLFHPWTADMPAHSPG-----ALPPPHPSL--GLTPQKTHLQP-------SFGAAHE
. . . .: .. ..: :.:: .: : : : . :: . . ..
NP_001 QVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQV
380 390 400 410 420 430
120 130 140 150 160
pF1KB8 LPLTPPADPSYPYEFSPVKMLP-SSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPP--
: .: :: .. :.. .:.. : .. : . . : ..: :
NP_001 LIRAPTLTPSGQISWQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVA
440 450 460 470 480 490
170 180 190 200 210 220
pF1KB8 --PPPPPPTCRQLSPNPAPDDLPWWSIPQAGA-GPGASGVPGS--GLSGACAGAPHAPRF
: . ::. : .: :. . :: : ..::: . ...: : .
NP_001 VAGAPITLNTAQLASVP---NLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQ
500 510 520 530 540 550
230 240 250 260 270
pF1KB8 PASAAAAAAAAAALQRGLV--LGPSDFAQYQSQIAALLQTKAPLAATARRCRR--CRCPN
:. : ...:.... . . ..:....: . : . ::. . ..: :: : :::
NP_001 QATIAPVTVAVGGIANATIGAVSPDQLTQVHLQQGQ--QTSDQEVQPGKRLRRVACSCPN
560 570 580 590 600 610
280 290 300 310 320 330
pF1KB8 CQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFT
:. . : ::::::::.::. ::::::::::::.::::::::::::.:::.:::: ::
NP_001 CREGEGRGSNEPGKKKQHICHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFT
620 630 640 650 660 670
340 350 360 370 380 390
pF1KB8 RSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDARDL
:::::::: ::::::::: ::::.:::::::::.::::::::::
NP_001 RSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDS
680 690 700 710 720 730
NP_001 SVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF
740 750 760
>>NP_003103 (OMIM: 600540) transcription factor Sp4 isof (784 aa)
initn: 812 init1: 705 opt: 746 Z-score: 285.1 bits: 62.6 E(85289): 3.9e-09
Smith-Waterman score: 758; 38.8% identity (59.9% similar) in 374 aa overlap (37-382:366-733)
10 20 30 40 50 60
pF1KB8 LRNDSLQAFLQDRTPSASPDLGKHSPLALLAATCSRIGQPGAAAPPDFLQVPYDPA--LG
::: :. .: .. :. .: : . :
NP_003 DTLVSSADTGQYASTSASSSERTIEESQTPAATESE-AQSSSQLQPNGMQNAQDQSNSLQ
340 350 360 370 380 390
70 80 90 100 110
pF1KB8 SPSRLFHPWTADMPAHSPG-----ALPPPHPSL--GLTPQKTHLQP-------SFGAAHE
. . . .: .. ..: :.:: .: : : : . :: . . ..
NP_003 QVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQV
400 410 420 430 440 450
120 130 140 150 160
pF1KB8 LPLTPPADPSYPYEFSPVKMLP-SSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPP--
: .: :: .. :.. .:.. : .. : . . : ..: :
NP_003 LIRAPTLTPSGQISWQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVA
460 470 480 490 500 510
170 180 190 200 210 220
pF1KB8 --PPPPPPTCRQLSPNPAPDDLPWWSIPQAGA-GPGASGVPGS--GLSGACAGAPHAPRF
: . ::. : .: :. . :: : ..::: . ...: : .
NP_003 VAGAPITLNTAQLASVP---NLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQ
520 530 540 550 560 570
230 240 250 260 270
pF1KB8 PASAAAAAAAAAALQRGLV--LGPSDFAQYQSQIAALLQTKAPLAATARRCRR--CRCPN
:. : ...:.... . . ..:....: . : . ::. . ..: :: : :::
NP_003 QATIAPVTVAVGGIANATIGAVSPDQLTQVHLQQGQ--QTSDQEVQPGKRLRRVACSCPN
580 590 600 610 620
280 290 300 310 320 330
pF1KB8 CQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFT
:. . : ::::::::.::. ::::::::::::.::::::::::::.:::.:::: ::
NP_003 CREGEGRGSNEPGKKKQHICHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFT
630 640 650 660 670 680
340 350 360 370 380 390
pF1KB8 RSDELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDARDL
:::::::: ::::::::: ::::.:::::::::.::::::::::
NP_003 RSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDS
690 700 710 720 730 740
NP_003 SVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF
750 760 770 780
>>NP_001017371 (OMIM: 601804) transcription factor Sp3 i (713 aa)
initn: 670 init1: 646 opt: 700 Z-score: 269.7 bits: 59.6 E(85289): 2.8e-08
Smith-Waterman score: 700; 77.6% identity (90.5% similar) in 116 aa overlap (269-382:525-639)
240 250 260 270 280 290
pF1KB8 GLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRR--CRCPNCQAAGGAPEAEPGKKKQH
.: :: : ::::. .:: .. ::::::
NP_001 SGDSTLNTNDLTHLRVQVVDEEGDQQHQEGKRLRRVACTCPNCKEGGGRG-TNLGKKKQH
500 510 520 530 540 550
300 310 320 330 340 350
pF1KB8 VCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRF
.::.:::::::::::::.::::::.:::::::::..::: :::::::::: :::::::.:
NP_001 ICHIPGCGKVYGKTSHLRAHLRWHSGERPFVCNWMYCGKRFTRSDELQRHRRTHTGEKKF
560 570 580 590 600 610
360 370 380 390
pF1KB8 ACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDARDL
.::::.::::::::::::.:::::::
NP_001 VCPECSKRFMRSDHLAKHIKTHQNKKGIHSSSTVLASVEAARDDTLITAGGTTLILANIQ
620 630 640 650 660 670
>>NP_001166183 (OMIM: 601804) transcription factor Sp3 i (778 aa)
initn: 725 init1: 646 opt: 700 Z-score: 269.3 bits: 59.6 E(85289): 2.9e-08
Smith-Waterman score: 700; 77.6% identity (90.5% similar) in 116 aa overlap (269-382:590-704)
240 250 260 270 280 290
pF1KB8 GLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRR--CRCPNCQAAGGAPEAEPGKKKQH
.: :: : ::::. .:: .. ::::::
NP_001 SGDSTLNTNDLTHLRVQVVDEEGDQQHQEGKRLRRVACTCPNCKEGGGRG-TNLGKKKQH
560 570 580 590 600 610
300 310 320 330 340 350
pF1KB8 VCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRF
.::.:::::::::::::.::::::.:::::::::..::: :::::::::: :::::::.:
NP_001 ICHIPGCGKVYGKTSHLRAHLRWHSGERPFVCNWMYCGKRFTRSDELQRHRRTHTGEKKF
620 630 640 650 660 670
360 370 380 390
pF1KB8 ACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDARDL
.::::.::::::::::::.:::::::
NP_001 VCPECSKRFMRSDHLAKHIKTHQNKKGIHSSSTVLASVEAARDDTLITAGGTTLILANIQ
680 690 700 710 720 730
>>NP_003102 (OMIM: 601804) transcription factor Sp3 isof (781 aa)
initn: 749 init1: 646 opt: 700 Z-score: 269.3 bits: 59.6 E(85289): 2.9e-08
Smith-Waterman score: 700; 77.6% identity (90.5% similar) in 116 aa overlap (269-382:593-707)
240 250 260 270 280 290
pF1KB8 GLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRR--CRCPNCQAAGGAPEAEPGKKKQH
.: :: : ::::. .:: .. ::::::
NP_003 SGDSTLNTNDLTHLRVQVVDEEGDQQHQEGKRLRRVACTCPNCKEGGGRG-TNLGKKKQH
570 580 590 600 610 620
300 310 320 330 340 350
pF1KB8 VCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRF
.::.:::::::::::::.::::::.:::::::::..::: :::::::::: :::::::.:
NP_003 ICHIPGCGKVYGKTSHLRAHLRWHSGERPFVCNWMYCGKRFTRSDELQRHRRTHTGEKKF
630 640 650 660 670 680
360 370 380 390
pF1KB8 ACPECGKRFMRSDHLAKHVKTHQNKKLKVAEAGVKREDARDL
.::::.::::::::::::.:::::::
NP_003 VCPECSKRFMRSDHLAKHIKTHQNKKGIHSSSTVLASVEAARDDTLITAGGTTLILANIQ
690 700 710 720 730 740
398 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:29:54 2016 done: Fri Nov 4 12:29:56 2016
Total Scan time: 8.730 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]