Result of FASTA (omim) for
pFN21AB8360
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8360, 168 aa
1>>>pF1KB8360 168 - 168 aa - 168 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2276+/-0.000295; mu= 14.0603+/- 0.019
mean_var=81.2056+/-15.755, 0's: 0 Z-trim(118.7): 43 B-trim: 0 in 0/51
Lambda= 0.142325
statistics sampled from 31789 (31833) to 31789 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.373), width: 16
Scan time: 4.500
The best scores are: opt bits E(85289)
NP_002816 (OMIM: 162095) pleiotrophin isoform 1 pr ( 168) 1167 248.3 4.4e-66
NP_001308315 (OMIM: 162095) pleiotrophin isoform 1 ( 168) 1167 248.3 4.4e-66
NP_001308316 (OMIM: 162095) pleiotrophin isoform 2 ( 167) 1150 244.8 4.9e-65
XP_016867962 (OMIM: 162095) PREDICTED: pleiotrophi ( 167) 1150 244.8 4.9e-65
NP_001257480 (OMIM: 162096) midkine isoform a prec ( 143) 509 113.1 1.8e-25
NP_001012334 (OMIM: 162096) midkine isoform a prec ( 143) 509 113.1 1.8e-25
XP_016873253 (OMIM: 162096) PREDICTED: midkine iso ( 143) 509 113.1 1.8e-25
NP_002382 (OMIM: 162096) midkine isoform a precurs ( 143) 509 113.1 1.8e-25
NP_001012333 (OMIM: 162096) midkine isoform a prec ( 143) 509 113.1 1.8e-25
XP_011518418 (OMIM: 162096) PREDICTED: midkine iso ( 143) 509 113.1 1.8e-25
NP_001257479 (OMIM: 162096) midkine isoform a prec ( 143) 509 113.1 1.8e-25
NP_001257481 (OMIM: 162096) midkine isoform b prec ( 87) 241 57.9 4.7e-09
>>NP_002816 (OMIM: 162095) pleiotrophin isoform 1 precur (168 aa)
initn: 1167 init1: 1167 opt: 1167 Z-score: 1307.4 bits: 248.3 E(85289): 4.4e-66
Smith-Waterman score: 1167; 100.0% identity (100.0% similar) in 168 aa overlap (1-168:1-168)
10 20 30 40 50 60
pF1KB8 MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTG
70 80 90 100 110 120
130 140 150 160
pF1KB8 SLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD
::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD
130 140 150 160
>>NP_001308315 (OMIM: 162095) pleiotrophin isoform 1 pre (168 aa)
initn: 1167 init1: 1167 opt: 1167 Z-score: 1307.4 bits: 248.3 E(85289): 4.4e-66
Smith-Waterman score: 1167; 100.0% identity (100.0% similar) in 168 aa overlap (1-168:1-168)
10 20 30 40 50 60
pF1KB8 MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTG
70 80 90 100 110 120
130 140 150 160
pF1KB8 SLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD
130 140 150 160
>>NP_001308316 (OMIM: 162095) pleiotrophin isoform 2 pre (167 aa)
initn: 1130 init1: 1079 opt: 1150 Z-score: 1288.6 bits: 244.8 E(85289): 4.9e-65
Smith-Waterman score: 1150; 99.4% identity (99.4% similar) in 168 aa overlap (1-168:1-167)
10 20 30 40 50 60
pF1KB8 MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTG
70 80 90 100 110 120
130 140 150 160
pF1KB8 SLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD
:::::::::::::::::::::::::::::: :::::::::::::::::
NP_001 SLKRALHNAECQKTVTISKPCGKLTKPKPQ-ESKKKKKEGKKQEKMLD
130 140 150 160
>>XP_016867962 (OMIM: 162095) PREDICTED: pleiotrophin is (167 aa)
initn: 1130 init1: 1079 opt: 1150 Z-score: 1288.6 bits: 244.8 E(85289): 4.9e-65
Smith-Waterman score: 1150; 99.4% identity (99.4% similar) in 168 aa overlap (1-168:1-167)
10 20 30 40 50 60
pF1KB8 MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTG
70 80 90 100 110 120
130 140 150 160
pF1KB8 SLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD
:::::::::::::::::::::::::::::: :::::::::::::::::
XP_016 SLKRALHNAECQKTVTISKPCGKLTKPKPQ-ESKKKKKEGKKQEKMLD
130 140 150 160
>>NP_001257480 (OMIM: 162096) midkine isoform a precurso (143 aa)
initn: 538 init1: 333 opt: 509 Z-score: 578.1 bits: 113.1 E(85289): 1.8e-25
Smith-Waterman score: 509; 48.4% identity (72.5% similar) in 153 aa overlap (9-161:2-142)
10 20 30 40 50 60
pF1KB8 MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSG
:.: : .: .. : :. .: : ::.: .: :.:.:: :. :.:.:
NP_001 MQHRGF---LLLTLLALLALTSAVAKKKDKVKKGGPGSECAEWAWGPCTPSSK
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 DCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTG
:::.: :::: :: ::.. ::..::::::.:::.:::.:. :: :: .:. :.: :
NP_001 DCGVGFREGT-CGA---QTQRI-RCRVPCNWKKEFGADCKYKFENWGACDGGTGTKVRQG
60 70 80 90 100
130 140 150 160
pF1KB8 SLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD
.::.: .::.::.:. ..::: :: .:..: :: .::
NP_001 TLKKARYNAQCQETIRVTKPC----TPKTKAKAKAKKGKGKD
110 120 130 140
>>NP_001012334 (OMIM: 162096) midkine isoform a precurso (143 aa)
initn: 538 init1: 333 opt: 509 Z-score: 578.1 bits: 113.1 E(85289): 1.8e-25
Smith-Waterman score: 509; 48.4% identity (72.5% similar) in 153 aa overlap (9-161:2-142)
10 20 30 40 50 60
pF1KB8 MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSG
:.: : .: .. : :. .: : ::.: .: :.:.:: :. :.:.:
NP_001 MQHRGF---LLLTLLALLALTSAVAKKKDKVKKGGPGSECAEWAWGPCTPSSK
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 DCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTG
:::.: :::: :: ::.. ::..::::::.:::.:::.:. :: :: .:. :.: :
NP_001 DCGVGFREGT-CGA---QTQRI-RCRVPCNWKKEFGADCKYKFENWGACDGGTGTKVRQG
60 70 80 90 100
130 140 150 160
pF1KB8 SLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD
.::.: .::.::.:. ..::: :: .:..: :: .::
NP_001 TLKKARYNAQCQETIRVTKPC----TPKTKAKAKAKKGKGKD
110 120 130 140
>>XP_016873253 (OMIM: 162096) PREDICTED: midkine isoform (143 aa)
initn: 538 init1: 333 opt: 509 Z-score: 578.1 bits: 113.1 E(85289): 1.8e-25
Smith-Waterman score: 509; 48.4% identity (72.5% similar) in 153 aa overlap (9-161:2-142)
10 20 30 40 50 60
pF1KB8 MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSG
:.: : .: .. : :. .: : ::.: .: :.:.:: :. :.:.:
XP_016 MQHRGF---LLLTLLALLALTSAVAKKKDKVKKGGPGSECAEWAWGPCTPSSK
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 DCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTG
:::.: :::: :: ::.. ::..::::::.:::.:::.:. :: :: .:. :.: :
XP_016 DCGVGFREGT-CGA---QTQRI-RCRVPCNWKKEFGADCKYKFENWGACDGGTGTKVRQG
60 70 80 90 100
130 140 150 160
pF1KB8 SLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD
.::.: .::.::.:. ..::: :: .:..: :: .::
XP_016 TLKKARYNAQCQETIRVTKPC----TPKTKAKAKAKKGKGKD
110 120 130 140
>>NP_002382 (OMIM: 162096) midkine isoform a precursor [ (143 aa)
initn: 538 init1: 333 opt: 509 Z-score: 578.1 bits: 113.1 E(85289): 1.8e-25
Smith-Waterman score: 509; 48.4% identity (72.5% similar) in 153 aa overlap (9-161:2-142)
10 20 30 40 50 60
pF1KB8 MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSG
:.: : .: .. : :. .: : ::.: .: :.:.:: :. :.:.:
NP_002 MQHRGF---LLLTLLALLALTSAVAKKKDKVKKGGPGSECAEWAWGPCTPSSK
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 DCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTG
:::.: :::: :: ::.. ::..::::::.:::.:::.:. :: :: .:. :.: :
NP_002 DCGVGFREGT-CGA---QTQRI-RCRVPCNWKKEFGADCKYKFENWGACDGGTGTKVRQG
60 70 80 90 100
130 140 150 160
pF1KB8 SLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD
.::.: .::.::.:. ..::: :: .:..: :: .::
NP_002 TLKKARYNAQCQETIRVTKPC----TPKTKAKAKAKKGKGKD
110 120 130 140
>>NP_001012333 (OMIM: 162096) midkine isoform a precurso (143 aa)
initn: 538 init1: 333 opt: 509 Z-score: 578.1 bits: 113.1 E(85289): 1.8e-25
Smith-Waterman score: 509; 48.4% identity (72.5% similar) in 153 aa overlap (9-161:2-142)
10 20 30 40 50 60
pF1KB8 MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSG
:.: : .: .. : :. .: : ::.: .: :.:.:: :. :.:.:
NP_001 MQHRGF---LLLTLLALLALTSAVAKKKDKVKKGGPGSECAEWAWGPCTPSSK
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 DCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTG
:::.: :::: :: ::.. ::..::::::.:::.:::.:. :: :: .:. :.: :
NP_001 DCGVGFREGT-CGA---QTQRI-RCRVPCNWKKEFGADCKYKFENWGACDGGTGTKVRQG
60 70 80 90 100
130 140 150 160
pF1KB8 SLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD
.::.: .::.::.:. ..::: :: .:..: :: .::
NP_001 TLKKARYNAQCQETIRVTKPC----TPKTKAKAKAKKGKGKD
110 120 130 140
>>XP_011518418 (OMIM: 162096) PREDICTED: midkine isoform (143 aa)
initn: 538 init1: 333 opt: 509 Z-score: 578.1 bits: 113.1 E(85289): 1.8e-25
Smith-Waterman score: 509; 48.4% identity (72.5% similar) in 153 aa overlap (9-161:2-142)
10 20 30 40 50 60
pF1KB8 MQAQQYQQQRRKFAAAFLAFIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSG
:.: : .: .. : :. .: : ::.: .: :.:.:: :. :.:.:
XP_011 MQHRGF---LLLTLLALLALTSAVAKKKDKVKKGGPGSECAEWAWGPCTPSSK
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 DCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTG
:::.: :::: :: ::.. ::..::::::.:::.:::.:. :: :: .:. :.: :
XP_011 DCGVGFREGT-CGA---QTQRI-RCRVPCNWKKEFGADCKYKFENWGACDGGTGTKVRQG
60 70 80 90 100
130 140 150 160
pF1KB8 SLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD
.::.: .::.::.:. ..::: :: .:..: :: .::
XP_011 TLKKARYNAQCQETIRVTKPC----TPKTKAKAKAKKGKGKD
110 120 130 140
168 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:06:44 2016 done: Fri Nov 4 12:06:45 2016
Total Scan time: 4.500 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]